... view of the person within the family. 53 Xiao is indeed family reverence,” but it is a different family reverence from that of the Jew, the Christian, or the Muslim Readers of the Classic of Family ... clinching their point In sum, then, the reader of the Classic of Family Reverence needs to keep in mind both the routine life of the people and the rapid pace of change and violence endemic to the ... value of the conceptions of the family and proper family relations in the three Abrahamic religions and will leave to others the question of whether the resultant familial institutions in the Western...
Ngày tải lên: 11/06/2014, 12:46
... [16] As the number of people on treatment continues to grow, there will be a need to go even further in the decentralization of care and develop models of chronic disease care outside of the formal ... triple therapy could be manufactured for less than a dollar a day This established a dynamic of global market competition that in 10 years has brought down the price of standard triple therapy ... uptake and retention Despite these major advances, there is a sense that many of the important lessons of the past decade are being forgotten In 2010, the high cost of treatment was again cited...
Ngày tải lên: 11/08/2014, 14:21
prychitko (ed.) - why economists disagree; an introduction to the alternative schools of thought (1998)
Ngày tải lên: 01/11/2014, 22:23
Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"
... purpose of this paper is to consider the potential for applying the available genetic modification (GM) technologies to the goal of achieving human germline gene therapy If germline gene therapy ... a variety of routes including pronuclear microinjection and SMGT [74, 75, 76] In the context of human germline gene therapy, such vectors offer the potential advantage of eliminating the threat ... contributed to the embryo, the resultant offspring will be chimeric (up to ca 50% of animals) The ESC contribution to a mouse can high (up to ca 80% of the cells), and will often include the germline...
Ngày tải lên: 03/11/2012, 10:01
Tài liệu Fertility, Family Planning, and Women’s Health: New Data From the 1995 National Survey of Family Growth pptx
... youngest child was 5–12 years of age, 20 percent of mothers of children 11–12 years of age allowed the child to care for her/himself at least part of the time while the mother was working For women ... percent of mothers 30–44 Family Planning and Other Medical Services Tables 70–83 show data on a number of aspects of use of family planning services and other medical services by women 15–44 years of ... The small decline in the percent receiving family planning services in the last 12 months—from 36.5 to 32.9 percent—may result from the aging of the population 15–44 years of age The number of...
Ngày tải lên: 12/02/2014, 23:20
Tài liệu Produced jointly by the British HIV Association (BHIVA), the British Association for Sexual Health & HIV (BASHH) and the Faculty of Family Planning & Reproductive Health Care doc
... 01/06/2007 06:58:00 There is limited and controversial data on the effect of HAART on the natural history of disease and so management of women should be the same whether receiving therapy or not ... with HIV/AIDS in the era of successful HIV therapy The incidence and prevalence of HIV infections continue to rise in the UK12 Due to the effectiveness of HIV treatment regimens there are now an ... testing prior to randomisation in the trial, the provision of antiretroviral therapy to those who develop HIV during the course of the study and the provision of adequate counselling advice to...
Ngày tải lên: 13/02/2014, 10:20
Tài liệu Fertility, Family Planning, and Reproductive Health of U.S. Women: Data From the 2002 National Survey of Family Growth doc
... The CDC’s Office of Women’s Health + + The Office of Planning, Research, and Evaluation of the Administration for Children and Families (ACF) + The Children’s Bureau of the ACF + The Office of ... toward the intendedness of pregnancies based on their own reports (13) + Of all births in the years before interview, 55 percent were intended by both the mother and the father (as reported by the ... 97,98) The NSFG is one of the few reliable sources of nationally representative data on the use of infertility services Earlier reports have documented the rise in use of these services through the...
Ngày tải lên: 13/02/2014, 10:20
Tài liệu Báo cáo khoa học: Molecular and cellular specificity of post-translational aminoacyl isomerization in the crustacean hyperglycaemic hormone family docx
... microscopy study of the neuronal endings in the sinus gland to determine the subcellular localization of the different epimers Taken together, these results allow a discussion of the existence of enzyme(s) ... terminal in the sinus gland, as a result of late and progressive isomerization of the Phe3 of the CHH during the migration of the secretion vesicles along the axonal tract [39,41] The immunohistochemical ... well-defined and restricted peptide family, as illustrated by a recent study of the I1-conotoxin superfamily [35] In the case of the CHH family, the occurrence of DAACPs appears to be problematic...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khoa học: Looking for the ancestry of the heavy-chain subunits of heteromeric amino acid transporters rBAT and 4F2hc within the GH13 a-amylase family ppt
... [3,11–13] Of the three GH families of the clan GH-H, it was the family GH13 that was originally established as the a-amylase family [14–17] At present it belongs to the largest families in the entire ... and S Janecek Origin of rBAT and 4F2hc within the GH13 a-amylase family Fig The CSRs of the hcHAT proteins and the GH13 a-amylase family members A list of the abbreviations of proteins and enzymes ... of the hcHAT proteins and the GH13 a-amylase family members The tree is based on the alignment of complete sequences and calculated including gaps The numbers represent the bootstrap values The...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family pptx
... to the residue in the midpoint of the respective loop, as shown in Fig To the east of the active site the 37- and 60-loops border the S2¢ pocket of the proteinase The observed differences in the ... below) The southern boundary of the active site cleft of DESC1 is formed by the 145 autolysis loop The backbone of this loop differs markedly from the other serine proteinases, making the active ... that the most similar regions of these proteinases mediate interaction of the two b-barrels, formation of the catalytic machinery and structures required for binding of the main chain of the substrate...
Ngày tải lên: 19/02/2014, 00:20
Tài liệu Báo cáo khoa học: Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family docx
... Reigstad et al endothelial growth factors (VEGF) and the family is therefore often referred to as the PDGF ⁄ VEGF family The PDGF family of growth factors The PDGF family consists of PDGF-A, -B, ... perivascular lymphoid cell infiltrates of the lung and fibrosis in the liver [110] Conclusions The novel members, PDGF-C and -D, of the PDGF subfamily of the cystine knot family of growth factors are potent ... strains developing fibrosis These findings suggest a role for the PDGF-C in the development of lung fibrosis One of the characteristics of pancreatic cancer is the overproduction of extracellular matrix...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khoa học: nsights into the reaction mechanism of glycosyl hydrolase family 49 Site-directed mutagenesis and substrate preference of isopullulanase doc
... composed of residues 25–540 The overall structure of the model of IPU and the mutated residues in this study are shown in Fig To elucidate the mechanism of the substrate recognition of IPU, two ... a-(1fi4)-linked glucose units of pullulan (Fig 4A) IPU is an anomer-inverting enzyme Comparison of the active sites of the model of IPU and Dex49A The active site structures of the model of IPU (Fig 4A) and ... compare the mechanism of hydrolysis of IPU and other GH family 49 dextranases, the anomer configuration of the hydrolysate of IPU was determined A polarimetric assay was carried out using panose as the...
Ngày tải lên: 19/02/2014, 16:20
Occupational therapy interventions and physical activity interventions to promote the mental wellbeing of older people in primary care and residential care pdf
... does the effectiveness of interventions depend on the characteristics of those delivering the intervention, the involvement of older people in their design and delivery or the involvement of family ... questions The key questions were established as part of the scope They formed the starting point for the reviews of evidence and facilitated the development of recommendations by PHIAC The overarching ... that the standards of practice for occupational therapy in the USA (American Occupational Therapy Association 2005) are consistent with the professional competency standards detailed in the post-qualifying...
Ngày tải lên: 05/03/2014, 18:20
Báo cáo khóa học: Mutational and computational analysis of the role of conserved residues in the active site of a family 18 chitinase docx
... positioned in the ÔupÕ position rows and shows that in the presence of the substrate, rotation of Asp142 towards Glu144 lowers the pKa of the latter by 0.8 pH units The calculated effects of the D140N ... for the position of residue 142 [34] The pKa calculations indicate that the only candidate for a residue determining the basic arm of the pH-activity profile of the D142N mutant is Glu144 The ... Mutation of subsets of these conserved residues in various family 18 chitinases has shown for the majority that they are important for catalysis [20,26–31] However, the mechanistic roles of several of...
Ngày tải lên: 07/03/2014, 14:20
The High Cost of High School Dropouts: What the Nation Pays for Inadequate High Schools ppt
... percentages of students who are eligible for free or reduced-price lunches (a measure of poverty).b High school students of low-income families drop out of high school at six times the rate of their ... out of high school was that they felt their classes were uninteresting and irrelevant.15 Others leave because they are not doing well academically According to the 2009 National Assessment of ... 30 percent of entering high school freshmen read proficiently,16 which generally means that as the material in their textbooks becomes more challenging, they drop even further behind The nation...
Ngày tải lên: 17/03/2014, 07:20
Fertility of Men and Women Aged 15–44 Years in the United States: National Survey of Family Growth, 2006–2010 docx
... because mothers report information for the birth registration system Not all mothers report information about the fathers of their babies, and if they do, their reports of the father’s age and other ... for the young woman and her child (1,17–19) There is debate on how much of the consequences of a teenage birth are the result of the mother’s earlier background characteristics rather than the ... women is the youngest of the three groups Although the majority of first births to black women are nonmarital, the majority are also outside of a cohabiting union These are some of the key findings...
Ngày tải lên: 22/03/2014, 11:20
Báo cáo khoa học: The proapoptotic member of the Bcl-2 family Bcl-2 / E1B-19K-interacting protein 3 is a mediator of caspase-independent neuronal death in excitotoxicity pot
... excitotoxicity BNIP3 is a BH3-only proapoptotic member of the Bcl-2 family However, unlike in other members of the Bcl-2 family, the BH3 domain of BNIP3 is not required for its death-inducing activity ... striatal areas adjacent to the site of injection (Fig 1A) High levels of BNIP3 immunostaining were found in the cytoplasm of striatal neurons affected by the KA, and almost all of the BNIP3positive neurons ... agonist for the kainate receptor (a subtype of the ionotrophic glutamate receptor) that mimics the effect of glutamate Of the 15 rats that received KA injections, five were used for preparation of brain...
Ngày tải lên: 22/03/2014, 17:20
Báo cáo khoa học: The allene oxide cyclase family of Arabidopsis thaliana – localization and cyclization ppt
... explains the impact of the protein environment on the stereoselectivity of the cyclization reaction As a result of the steric restrictions in the cavity, changes in the position of the epoxide ... stereoselectivity of the reaction (Table [23]) To further characterize the importance of the hydrophobic environment inside the binding pocket of AOC2, and to assess the role of the amino acids forming the ... double bond The delocalization of the positive charge between C13 and C16 promotes the opening of the oxirane (Fig 2A) and the cyclization reaction by the mechanism of anchimeric assistance The formed...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: In silico analysis of the adenylation domains of the freestanding enzymes belonging to the eucaryotic nonribosomal peptide synthetase-like family pot
... accession no Q7QKF0) where the Asp235 is missing In this latter case, the absence of the Asp235 can be explained in the light of the model of the interaction of the substrate with the active site (vide ... involves the formation of a salt bridge between the a-amino group of the substrate and the carboxylic group of Asp235 and a hydrogen bond to the carbonyl atom of Ser330 The d-aldehyde group of the ... the substrate a-carboxylate interacts via hydrogen bonds with the e-amino group of Lys517 The other residues of the putative specificity code line the walls of the active site In particular, the...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: The role of residues R97 and Y331 in modulating the pH optimum of an insect b-glycosidase of family 1 pdf
... As the pKa values of the catalytic residues determine the pH optima, the ionization constants (pKa) of the catalytic glutamates (E187 and E399) in the ES complex and in the free enzyme (E) of ... deglycosylation) of the hydrolysis of MUbglc by the mutant enzymes is rate-limiting, no hypothesis on the effect of R97 and Y331 on the rate constant of each step can be advanced ể FEBS 2003 Mechanism of ... result, the pH optimum of the Y331F mutant (7.0) is higher than that of the wild-type Sfbgly50 (6.2) (Fig 5) The effect of this mutation on the E399 ionization is the same as observed for the mutation...
Ngày tải lên: 23/03/2014, 15:21