... highly twisted as a result of the conserved flexible Gly5 followed by the bulky side chain of lysine and the disulfide-paired Cys7, which pulls the strand towards Structure and dynamics of an antifungal ... the present study, we report the 3D structure and backbone dynamics of PAF by 2D homonuclear and 3D 15 N resolved heteronuclear NMR spectroscopy and demonstrate the functional importance of the ... 10. The electrostatic surface potential of AFP (left) and PAF (right) structures representing the orientation of the side chain lysine resi- dues. Lys9, Lys35 and Lys38 of PAF and Lys9, Lys32 and
Ngày tải lên: 29/03/2014, 23:20
... modules, CCP1 and CCP2, of C1r in their free form, as well as their tandem-linked construct, CCP1CCP2, to characterize their solution structure, conformational dynamics and cooperativity. The structures ... to the termini of the module, which define the two apices of the some- what ellipsoidal protein. CCP structures are highly variable, with the invariant parts comprising mainly the b-strands. The ... CCP1 single and CCP2 single modules and probably reflects the complex interdependence of the modules in terms of internal dynamics and may also be a consequence of the large anisotropy (devia- tion from the
Ngày tải lên: 15/03/2014, 23:20
Báo cáo y học: "Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species" docx
... have an effect on the estimated value of the mutation rate and on the branch length of the phylogenetic tree However, they not affect the structure of the tree and the estimates of the recombination ... tree obtained using the SNPs of the core genome of the 44 strains of S pneumoniae, strains of S mitis and strain each of S oralis and S infantis For clarity the clade containing the S pneumoniae ... genes, and the genome of the common ancestor of S pneumoniae and S mitis encoded 2,039 genes For comparison, the average number of genes of S pneumoniae is 2,104, and the average number of genes
Ngày tải lên: 09/08/2014, 22:23
Báo cáo hóa học: " Effect of thermal treatment on the growth, structure and luminescence of nitride-passivated silicon nanoclusters" pptx
... While the properties of this luminescence have been observed to depend on the size of the Si-ncs, difficulties arise in the understanding of these materials from the effects related to the Si-nc/dielectric ... secondary electrons and fluorescence photons at the absorption edges probed. Information on the bulk of the film was provided by the TEY spectra at the Si K-edge and the FLY spectra at the Si L 3,2 ... increased. There appear to be at least two competing mechanisms in the Si-nc growth dynamics related to the growth of existing Si-ncs due to diffusion of silicon ato ms in the film and the formation and
Ngày tải lên: 21/06/2014, 05:20
The intellectual structure and substance of the knowledge utilization field: A longitudinal author co-citation analysis, 1945 to 2004 pdf
... context, and differences in the nature of the producers and users of the knowledge as well as the particular goals each holds within their con- text. In the health arena, the consequences of not ... of scientific work (publications) and the actual processes of forming knowledge [106]. Merton is cited in this decade for the first and revised editions of his book: " ;Social Theory and Social ... sociometric methods, the latter with bibliometric methods. The emergence or strengthening of an invisible college on one hand or the weakening or loss of one altogether on the other, signal important
Ngày tải lên: 11/08/2014, 05:21
báo cáo khoa học: " The intellectual structure and substance of the knowledge utilization field: A longitudinal author co-citation analysis, 1945 to 2004" potx
... context, and differences in the nature of the producers and users of the knowledge as well as the particular goals each holds within their con- text. In the health arena, the consequences of not ... diffusion paradigm; rather, there is a spread of the paradigm to other fields and areas of specialization We do see, however, from the titles of the articles of the most-cited ... of scientific work (publications) and the actual processes of forming knowledge [106]. Merton is cited in this decade for the first and revised editions of his book: " ;Social Theory and Social
Ngày tải lên: 11/08/2014, 16:21
ab initio investigation of the thermochemistry, spectroscopy and dynamics of reactions between mercury and reactive halogen species
... generally accepted, the mechanism of the MDEs and the ultimate fate of the mercury is still very uncertain One of the complications in elucidating the mechanism is that some of the observed MDEs ... (ag) and angles of the mercury hypohalites computed at the CCSD(T)/aVQZ level of theory Harmonic vibrational frequencies (em”) of the mercury hypohalites computed at the MP2/aVTZ level of theory ... leading to the formation of XHgOY are barrierless These results support the hypothesis of Calvert and Lindberg”! that the mercury hypohalite species could be a major component of RGM The MCSCF and linear
Ngày tải lên: 14/11/2014, 13:35
genomic insights into the population structure and history of the irish travellers
... iii) estimate the time of divergence between the Travellers and settled Irish, and iv) the levels of autozygosity within the Irish Traveller population Results Population Structure of the Irish Travellers. ... context of Britain and Ireland, not the full structure found within Britain and Ireland The results are presented in Fig. 1 in the form of a principal component analysis of fineStructure’s haplotype-based ... segments of different length intervals using the theory of ref 17, and found the parameters of the demographic model that best fitted the data (see Supplementary Data 1.3, Fig. 5B, and Table 1) The
Ngày tải lên: 04/12/2022, 10:35
Impacts of social networks on consumers’ trust and behavior in the Vietnamese retail sector
... Abstract: The goal of the study is to analyze social networking related factors influencing consumers’ trust and intent to purchase online via social networks in the Vietnamese market The model of social ... application of ratings and reviews Customers can access the websites of suppliers to read reviews and ratings of their friends and other customers Reading these ratings and feedback from other buyers is ... in purchasing and selling via social networks [17] Useful, simple, and easy-tounderstand information on the social network of sellers increases online trust and therefore increases the purchasing
Ngày tải lên: 27/09/2020, 17:37
Impacts of social networks on consumers’ trust and behavior in the vietnamese retail sector
... Abstract: The goal of the study is to analyze social networking related factors influencing consumers’ trust and intent to purchase online via social networks in the Vietnamese market The model of social ... application of ratings and reviews Customers can access the websites of suppliers to read reviews and ratings of their friends and other customers Reading these ratings and feedback from other buyers is ... in purchasing and selling via social networks [17] Useful, simple, and easy-tounderstand information on the social network of sellers increases online trust and therefore increases the purchasing
Ngày tải lên: 17/03/2021, 20:26
Báo cáo khoa học: Structure and topology of the transmembrane domain 4 of the divalent metal transporter in membrane-mimetic environments docx
... represent the NMR structures The quality of the final structures was accessed using the program of PROCHECK-NMR [35] Further analysis and visualization of the conformers including calculation of root ... structures of DMT1-TM4 in both SDS (pH 6.0) and TFE were chosen to represent the solution structures of the peptide, as shown in Fig The quality of the final structures was assessed using the program ... disappearance of the cross-peaks of Ala13 in the TOCSY spectrum (Fig 6B), a significant reduction in intensities of the cross-peaks of Leu9 and Phe16, and a moderate reduction in intensities of the cross-
Ngày tải lên: 16/03/2014, 16:20
Báo cáo khoa học: Effect of mutations in the b5–b7 loop on the structure and properties of human small heat shock protein HSP22 (HspB8, H11) pptx
... However, the overall structures of aB-crystallin and HSP27 predicted by these two models are very similar, and the positions of the b-strands correlate well with the corresponding positions of the ... sHsp The primary structure of the a-crystallin domain of human sHsp is very conservative and the loop connecting the b5 and b7 strands is shorter than the corresponding loop connecting the b5 and ... and in the N-terminal part of the b7 strands destabilize the structure of HSP22 Limited trypsinolysis of the wild-type HSP22 and its K137E and K137,141E mutants Fig Far-UV CD spectra of the wild-type
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: Solution structure and stability of the full-length excisionase from bacteriophage HK022 pot
... between the two a-helices), these structures can be superposed with a backbone RMSD of 0.71 A ˚ . The statistics of the final structure calculation are summarized in Table 2. The global structure of ... between b-strands 3 and 4. The b-strands 2 (residues Ile30–Phe31) and 5 (residues Val48–Lys49) form the second b-sheet. The Fig. 4. Identification of the IsoAsp66–Gly67 connectivity. (A) The deamidation of ... as the DNA-binding domain of the Mu repressor [21]. Third, the backbone atoms of the region comprising the ÔwingÕ b-sheet (residues 2–4, 35–36 and 41–44 of HK022 Xis and residues 16–18, 47–48 and 58–61
Ngày tải lên: 23/03/2014, 15:21
Báo cáo khoa học: H NMR study of the molecular structure and magnetic properties of the active site for the cyanomet complex of O2-avid hemoglobin from the trematode Paramphistomum epiclitum pdf
... from the heme normal (z¢ axis), a is the angle between the projection of the tilt of the z axis on the x¢, y¢ plane (defined direction of tilt of z and the x¢ axis), and j % a + c defines the location ... ligated water molecule The two structures of WT metHb and rWT metHbH2O, exhibit significant differences in the interaction of the FG loop with the heme and in the position of the B-helix, with ˚ ... of WT and the other of rWT metHb, exhibit differences that include important portions of the protein that we have characterized above Thus parts of the FG corner move away from the heme and the
Ngày tải lên: 23/03/2014, 17:22
Báo cáo khoa học: Structure and function of the 3-carboxy-cis,cis-muconate lactonizing enzyme from the protocatechuate degradative pathway of Agrobacterium radiobacter S2 pdf
... in the mutant First, there is an increase in the negative charge in the active site and, second, breaking the salt bridge would alter the quaternary structure of the protein and therefore the ... in the ArCMLE1 structure The figure was created from the coordinates of the P212121 structure of ArCMLE1 and of PpCMLE (Protein Data Bank code 1RE5) (B) Water cavity below the active site The ... competitive 0.98 and 121 versus noncompetitive 0.99 and 58 Site-directed mutagenesis of ArCMLE1 From the crystal structure of the P putida CMLE [6] and sequence comparisons with other members of the fumarase
Ngày tải lên: 30/03/2014, 10:20
Báo cáo khoa học: Structure and activity of the atypical serine kinase Rio1 doc
... with the uncomplexed protein. Com- parisons of the structure of Rio1 with the previously determined structure of the Rio2 kinase defined the minimal RIO domain and the distinct fea- tures of the ... Asp99 and Phe102, Met104 and Ile107, and Ser108 and Glu111, which marks the start of aC. The entire flexible loop packs between the N-terminal portion of aC and part of the C-lobe (Figs 2A and 3A). The ... part of the adenine ring of ATP (Fig. 2B). No equivalent fea- ture was seen in the structure of Rio2 or in any other kinase structures that we examined. As a result of the presence of the flap, the
Ngày tải lên: 30/03/2014, 20:20
Environment and health risks: a review of the influence and effects of social inequalities pptx
... on the environmental risk and the “risk group” considered, the magnitude of inequality varies largely. The realization of the social pattern in risk exposure has resulted in the adoption of ... better understanding of the impact of social inequalities on the distribution of environmental risks, this report presents a compilation of European evidence on the impact of social determinants ... residences ) and according to the land price, which favours the creation of social “ghettos,” the rich and the poor living in very different locations In terms of sources of air
Ngày tải lên: 28/06/2014, 23:20
Báo cáo lâm nghiệp: "Structure and development of forest stands on permanent research plots in the Krkonoše Mts" pdf
... erentiation of the forest stand Table 1 gives overview of all three structural in- dices used in the study. The horizontal structure of the forest stand was from the first year of ob- servation ... erentiation of the forest stand Table 3 gives overview of all three structural in- dices used in the study. e horizontal structure of the forest stand was from the fi rst year of obser- vation random; ... years the stand tends to more aggregation, after 2022 clumped structure of the stand is predicted. e spatial diversity of the stand is medial with slight increase as result of higher ratio of
Ngày tải lên: 07/08/2014, 10:21
Báo cáo khoa học: Eukaryotic class 1 translation termination factor eRF1 ) the NMR structure and dynamics of the middle domain involved in triggering ribosome-dependent peptidyl-tRNA hydrolysis pptx
... superimpo- sition of five-residue segments of the crystal structure on the equivalent segments of each member of the family of the solution structure of the M domain of human eRF1. The resulting rmsd ... S4. A comparison of part of the protein backbone structure of the representative solution structure of the human eRF1 M domain and the Ca trace in the crystal structure of RF1 in the whole ribosome ... simi- larity to the crystal structure of the M domain of the same protein [3], but it is far from identical (Fig. 2A). The rmsd of the superposition of the heavy backbone atoms (Ca, N, O and C) of the family...
Ngày tải lên: 07/03/2014, 05:20
Cambridge.University.Press.Fearing.Others.The.Nature.and.Treatment.of.Social.Phobia.Mar.2007.pdf
... examine the validity of the measures devised to ascertain and quantify social anxiety, as this is most relevant to social phobia. Examination of the validity both of the construct and of the methods assessing ... comparison to the normal, the social phobic response is exaggerated, over-generalized, and chronic. The issues raised by these incompatible points of view attending the inception of the notion of social ... heightened sense of propriety and blushing were expressions of shame. Social anxiety is evoked socially The Genealogy of Social Phobia 19 To my wife and to the memory of my mother À who taught...
Ngày tải lên: 21/09/2012, 10:54