... filtered into the interior, and so reached the pipes of the Chinese. Just why the Chinese chose to obtain their supplies from India is no clearer than why, having obtained it, they smoked instead ... departure. They do not pretend, or even think, that they are not Chinese. They are somewhere in the middle. And that, in the circumstances of enormous energy in a very tight space, is exciting. It ... Peace, and other nostrums containing the drug. But working mothers paid no attention to such warnings. They had to leave their infants in the care of old women or very young children when they went...
Ngày tải lên: 11/06/2014, 14:18
Ngày tải lên: 05/09/2013, 09:08
Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx
... provided further insight into the molecular mechanism driving the formation of the covalent C115–fosfomycin adduct. A conservative exchange of K22 to arginine maintains fosfo- mycin binding, while ... lysine reduces the probability of forming the fully closed form of the protein. The results obtained with the K22V/R120K double mutant protein point toward a central role of arginine 120 in the ... uncharged valine side chain completely abolishes fosfomycin binding in the absence of UDPNAG. Clearly, UDPNAG binding creates additional favorable interactions that promote fosfomycin binding to the enzyme....
Ngày tải lên: 19/02/2014, 13:20
Tài liệu The Buccaneers in the West Indies in the XVII Century pdf
... were evidently relaxing, for in 1634 the Conde de Humanes confided to the English agent, Taylor, that there had been talk in the Council of the Indies of admitting the English to a share in the freight ... pounds sterling.[21] In view of the prevailing east wind in these regions, and the maze of reefs, cays and shoals extending far out to sea from the Mosquito Coast, the galleons, in making their course ... workmen, the increase of imposts, and the prejudice against the mechanic arts, industry was being ruined; while the increased depopulation of the realm, the mainmort of ecclesiastical lands, the majorats...
Ngày tải lên: 21/02/2014, 14:20
Báo cáo khoa học: Role of the hinge peptide and the intersubunit interface in the swapping of N-termini in dimeric bovine seminal RNase pptx
... process are located in regions different from the hinge loop 16–22. In the search for the region primarily involved in the swapping, we focused our attention on the interface between the subunits. In ... of the parent protein, and investigated the exchange kinetics of the corresponding dimers. The P19A mutation slightly increases the thermal stability of the monomer, but it does not alter the ... about 7 : 3. Kinetic analysis of the swapping pro- cess for a recombinant sample shows that it folds mainly in the MẳM form, then undergoes interconversion into the MxM form, reaching the same 7...
Ngày tải lên: 16/03/2014, 23:20
Research " AUDITING IN THE DATA PROCESSING ENVIRONMENT — THE EVOLVING ROLE OF THE INTERNAL AUDITOR " ppt
Ngày tải lên: 23/03/2014, 05:23
Alice’s Adventures in WonderlandBy Lewis Caroll (1865)Download free eBooks of classic literature, books and novels at Planet eBook. Subscribe to our free eBooks blog and email newsletter..All in the Golden AfternoonAll in the golden afternoon Full ppt
... hat,’ the King said to the Hatter. ‘It isn’t mine,’ said the Hatter. ‘Stolen!’ the King exclaimed, turning to the jury, who in- stantly made a memorandum of the fact. ‘I keep them to sell,’ the ... being run over; and the moment she appeared on the other side, the puppy made another rush at the stick, and tumbled head over heels in its hurry to get hold of it; then Alice, think- ing ... the things get used up.’ ‘But what happens when you come to the beginning again?’ Alice ventured to ask. ‘Suppose we change the subject,’ the March Hare inter- rupted, yawning. ‘I’m getting tired...
Ngày tải lên: 24/03/2014, 00:20
The Million Person Gap: The Arab Population in the West Bank and Gaza docx
... documents from the CEC and all mathematical calculations based on them are presented in their entirety in Appendix F.) Areas for Further Revision in the PCBS Forecast By changing some migration ... of the population below 18 in the West Bank and 48.3% below 18 in Gaza, the 1.3 million adult residents would indicate a total population in the Territories of 2.34 million people. cxxix (The ... delineated. If the PCBS removes these groups from its population base, its birth projections will fall into line with figures recorded by other PA agencies, including the agencies that the PCBS itself...
Ngày tải lên: 29/03/2014, 08:20
Báo cáo khoa học: Towards understanding the functional role of the glycosyltransferases involved in the biosynthesis of Moraxella catarrhalis lipooligosaccharide ppt
... irradiating each of the anomeric signals in turn to obtain the 1 H chemicals shifts of the corresponding remaining ring protons. Again, assignment of the Kdo residue was possible from examination ... to the (1 fi 4) chain and also to the (1 fi 6) chain in serotype B strains. Lgt4 (present only in serotypes A and C), then adds an a-(1 fi 2)- GlcNAc to the (1 fi 4) chain instead of Glc. Lgt2 A (in serotype ... strains, there is an a-d-GlcNAc residue with a (1 fi 2) glycosidic link- age on the (1 fi 4) chain. To further investigate the function of Lgt4 and to explore the interrelationship between the...
Ngày tải lên: 30/03/2014, 08:20
Báo cáo khoa học: Regulation of the muscle-specific AMP-activated protein kinase a2b2c3 complexes by AMP and implications of the mutations in the c3-subunit for the AMP dependence of the enzyme docx
... possible that the antibody binding itself interferes with the AMP-bind- ing properties of c3. Additionally, the low A 0.5 value characterizing the activation of a2b2c3 trimer by AMP makes the system ... Lipofectin reagent, according to the manufacturer’s instructions (Invi- trogen). Immediately prior to the lysis, the cells were sub- mitted to hyperosmotic stress by incubating them for 30 min with ... ATP, occurring in eukaryotic cells only, have an impact on the activity of the enzyme. Further studies in relevant cell systems as well as in animal models are required to investigate these issues. Experimental...
Ngày tải lên: 30/03/2014, 08:20
Báo cáo khoa học: Salt-inducible kinase-1 represses cAMP response element-binding protein activity both in the nucleus and in the cytoplasm pdf
... in bold. The basic residues in domain 3B are indicated by underlines. The similarity between SIK1 and SIK2 in domain 3A, the N-terminal half of domain 3, is higher than that in domain 3B, the C-terminal ... zipper domain (b-ZIP) minus CREB [CREB (S): (right panel)] were investigated by using the Gal4 DNA-binding domain-linked assay. Cells were transformed with the Gal4 DNA-binding domain-linked CREB ... another shuttling kinase, is involved in the regulation of translation initiation by activating p70 S6 kinase and phosphorylating eIF-4E-binding protein [52]. When FRAP was restricted to the...
Ngày tải lên: 30/03/2014, 15:20
Báo cáo khoa học: Role of the N- and C-terminal regions of the PufX protein in the structural organization of the photosynthetic core complex of Rhodobacter sphaeroides pptx
... the role of the C-terminal amino-acid residues of the LH1 a polypeptide in the organization of the LH1–RC complex [12]. In the present work, we have investigated the possible involvement of the ... PufX72* and PufX68* (Fig. 5B) could in principle either reflect an impairment in the insertion into the membrane of the shortened protein and/or in the assembly of PufX in the LH1–RC, or resides at transcriptional/post-translational level. ... the cyt bc 1 in the presence of mutated PufX protein The role of the PufX protein in facilitating the ubiquinone/ ubiquinol exchange between the Q B site of the RC and the ubiquinone pool has...
Ngày tải lên: 31/03/2014, 09:20
d. Hadn''''t it been b 41. The talks in the classroom, in the corridor and in the schoolyard do not pdf
... a 15. They …………. all kinds of sackcloth. a. produce b. do c. audit d. deposit > a 16. They used to go skiing in the mountain every winter, but for the past five years. a. they don’t ... are incorrect > b a. spends b. spend c. spent d. will spend >a 18. They don't let me take a taxi. They insist in their car. a. me to come b. on my coming c. on me coming ... find / to buy / trying / to travel b. see / wasn’t / to find / to buy / trying / to travel c. to see / wasn’t / to find / buy / trying / to travel d. seeing / am not / to find / buy / trying...
Ngày tải lên: 18/06/2014, 17:20
báo cáo hóa học: " Hypoxia silences the neural activities in the early phase of the phrenic neurogram of eupnea in the piglet" docx
... neurograms during eupnea and compared them with those of gasping in order to investigate the similarities between these patterns. Our preliminary data indicated that the patterns during early and ... during maturation. The dominant burst type activ- ities disappeared during the early phase of the phrenic neurogram although the burst activity and the continuous activity remained, but both them ... influence phrenic neurons responsible for the neural activities in the late phase of the phrenic neurogram dur- ing inspiration. In addition, it also significantly increases the duration of the...
Ngày tải lên: 19/06/2014, 10:20
Báo cáo hóa học: " The first nontrivial curve in the fučĺk spectrum of the dirichlet laplacian on the ball consists of nonradial eigenvalues" pptx
... the point (s, 0) in the (l + , l - )-plane. The first two intersections coincide with the points (l 1 , l 1 - s )and(l 1 + s, l 1 ). This fact follows from the radial symmetry of the principal ... t)u + − tu − in , u =0 on∂ holds in the weak sense. In particular, (l + , l - )=(s + t, t) Î Σ.Takingv = u in (2), one can see that the Lagrange multiplier t is equal to the corresponding critical ... in( 0,∞) . (13) Note that the functions v and ˆ v have the same zeros. Let us investigate the radial Fučík eigenvalues which lie on the line parallel to the diagonal and which passes through the...
Ngày tải lên: 20/06/2014, 22:20
báo cáo hóa học: " Mild solutions for a problem involving fractional derivatives in the nonlinearity and in the non-local conditions" ppt
... conditions is investigated. This model covers many of the existing models in the literature. It extends the integer order case to the fractional case in the sense of Caputo. A fixed point theorem is used ... strongly continuous cosine family C(t), t ≥ 0ofbounded linea r operators in the Banach space X and f, g are nonlinear functions from R + ì X ì X to X, u 0 and u 1 are given initial data in X. The functions ... different fixed point theorems and the theory of strongly continuous cosine families in Banach spaces. We refer the reader to [7,9,10] for a good account on the theory of cosine families. Fractional...
Ngày tải lên: 21/06/2014, 02:20
Báo cáo toán học: "Remarks on the singular extension in the C*-algebra of the Heisenberg group " docx
Ngày tải lên: 05/08/2014, 10:20
Báo cáo y học: " The role of the bronchial microvasculature in the airway remodelling in asthma and COPD" pps
Ngày tải lên: 12/08/2014, 11:22
Báo cáo y học: "Changes in the mechanical properties of the respiratory system during the development of interstitial lung edema" ppt
Ngày tải lên: 12/08/2014, 15:21