the dred scott decision is important because

Ngày tải lên: 11/08/2014, 14:21

... 6]. Identification of the region causing different association characteristics The difference in association characteristics of the enzyme from the two sources was surprising because the sequence is extremely ... Biochem. 269) Ó FEBS 2002 This amino acid is located in the insert within the catalytic domain, close to the catalytic His264, and the proximity to the active site may explain the effect of oligomerization ... arge insertion between the catalytic Asp and His in TPP II. This region would, of course, be difficult to model, but as Arg252 is so close to H is2 64, where the structure is conserved, the model is still expected...

Ngày tải lên: 21/02/2014, 15:20

... [42,44]. The importance of glycosylation is highly variable, therefore, and even in cases where it is important, the effect may be either direct or indirect. In this study, we set out to explore the ... 4A). Although these results attest to the importance of N-glycosylation for the normal cellular localization of HFE, we wondered whether this was a cumulative effect or whether there are specific ... sequenced. Throughout the text and figures, the protein expressed from this construct is frequently referred as the triple mutant. Mutated HFE cDNAs were subcloned into the BglII/ SalI sites of the pEP7–GFP...

Ngày tải lên: 06/03/2014, 22:21

... conformation of the active site is not significantly changed on removal of the HBD. Because the HBD is important for sub- strate binding, the HBD may affect the interaction between the enzyme and ... alter the interaction between the sub- strate and metal ion, such that the scissile phosphate group of the substrate and the Mg 2+ ion are arranged ideally. The effect of this alteration on the coordination ... Tma-RNase HI. Likewise, the stability of Tma-W22A was not analyzed because the stability of Tma-W22A is not significantly changed even when the HBD is completely removed, and therefore it is highly likely...

Ngày tải lên: 06/03/2014, 22:21

Ngày tải lên: 31/03/2014, 08:20

Ngày tải lên: 31/03/2014, 08:20

Ngày tải lên: 11/08/2014, 11:21

Ngày tải lên: 12/08/2014, 23:22

... which they are involved? + The MODE OF DISCOURSE concerns what part the language is playing, what it is that the participants are expecting the language to do for them in that situation, the symbolic ... is thus a theory of the global distribution of the units of the grammar. The English grammatical rank scale recognized by Systemic Functional Grammar is as follows: In turn, each unit has their ... English Theme is the first element of a clause and providing what we call the departure for the starting point for the clause. By changing Theme we do not change the ideational meaning but the...

Ngày tải lên: 07/11/2012, 14:44

... hóa Việt được con người mang theo từ buổi đầu mở đất vào phương nam, do trải qua các biến cố lịch sử xã hội nên đã có những thay đổi phù hợp với hoàn cảnh mới. Theo hướng đồng đại, ngoài yếu ... Điều này sẽ được trình bày cụ thể ở mục “Nguồn gốc” của chương hai và ba luận văn. Theo quy luật ngôn ngữ, theo xu thế phát triển của xã hội Việt Nam hiện nay, việc người dân di chuyển từ nơi ... triển riêng, gắn với đặc điểm xã hội và tâm lí con người địa phương. Về nguyên tắc làm việc, theo chúng tôi, muốn xác định đó có phải từ địa phương Nam Bộ hay không, người ta phải căn cứ vào...

Ngày tải lên: 17/04/2013, 16:09

... engaging the lug of the scabbard with the slot in the bayonet, ensuring that the sharp edge of the bayonet faces away from the hook end of the scabbard. The wedge shape on the back of the blade ... muzzle of the rifle. The blade end of the handle is a release catch which secures it onto the muzzle of the rifle. The blade end of the handle can be used as a bottle opener. THE SCABBARD is normally ... British Army Infantry Weapons: Worksheet One 1. The following are the names of parts of the three main weapons used by the British Infantry. Can you put the names on the pictures below in the...

Ngày tải lên: 25/10/2013, 18:20

... Safe Senders List The Safe Senders list is part of the Junk E-mail filters. If you choose to allow external content from addresses listed in your Safe Senders list, you need to check the configuration ... select Add Sender to Safe Senders List or Add the Domain @[domain-name] to Safe Senders List. The sender's fully qualified domain name is listed in the menu selection, as shown previously ... you need to check the configuration of the list. You can add addresses and domains to the Safe Senders list directly from an email message. Click on the InfoBar or right-click in any image...

Ngày tải lên: 21/01/2014, 02:20

... quantitative real-time PCR analysis indicated that AtHELPS is mainly expressed in the vascular tissues, such as the midrib of the cotyledon, the hypocotyl, and the root vasculature (Fig. 2E), and is upregulated ... III, IV, V, and VI. The arrow marks the highly conserved residues Asp-Glu-Val-His in motif II. The detailed scheme of the conserved motifs in AtHELPS is shown on the underside. The amino acids in ... analysis of the T-DNA insertion for the helps mutant and OE lines of AtHELPS. (A) The conserved motifs of DExD ⁄ H-box RNA helicases in AtHELPS. Numbers represent the amino acid position of the AtHELPS...

Ngày tải lên: 14/02/2014, 18:20

Ngày tải lên: 18/02/2014, 04:20

... line on the right), where the 19 amino acid insertion of Rac1b is found, is disordered in the crystal. The mostly disordered structures of the switch II region are compati- ble with important ... addition. Therefore, the reason why Lys147 rather than Lys5 is the main acceptor site for ubiquitin in Rac1 remains to be elucidated. Of note, however, is that recent studies on the role of the Rab-like ... supplied by the authors. Any queries (other than missing material) should be directed to the corre- sponding author for the article. Ubiquitination of Rac1 is regulated by JNK O. Visvikis et al. 396...

Ngày tải lên: 18/02/2014, 16:20

... most other vertebrate AChEs is missing in C. intestinalis AChE, Tyr70, a member of the peripheral site, which is replaced by Ile97. The K ss of C. intestinalis AChE for ATCh is rather high and this ... intestinalis AChE is the longest in the tree; this long branch length is typical of many C. intestinalis genes and is a result of rapid evolution in the species [34,37]. This rapid evolution and the ... AChE T exon, as only one of the seven aromatic residues is preserved. It is highly unlikely that this protein is an active AChE because it is missing a member of the catalytic triad and the main aromatic...

Ngày tải lên: 18/02/2014, 17:20

... events, theater, and dance. Christie is leading the industry in developing HFR technology, and is in the process of rolling out a transition plan for exhibitors. The drive is on to make theater ... the color information must be discarded to allow the video data to move across this interface. Some observers suggest the visual impact is minimal, but it’s nonetheless a quality compromise. ... director James Cameron is working with Christie in leading the global R&D effort to make the industry ready for this big shift – from the film set and all the way to the local movieplex. HFR...

Ngày tải lên: 19/02/2014, 10:20

... 1 80 85 90 95 100 105 110 average central bank loss STR p Warsaw, November 2008 The Relativity Theory Revisited: Is Publishing Interest Rate Forecasts Really so Valuable? 0LFKDï%U]R]D%U]H]LQD Adam ... Ř 5HVXOWVRIVLPXODWLRQV  DUHGHSLFWHGLQ)LJXUHVDQG$VWKHVDPSOHOHQJWKhbea used by agents rises the central bank loss tends to be lower. This is in line with the intuition WKDWXVLQJODUJHUGDWDVHWVE\DJHQWVHQDEOHVWKHPWREHWWHUDSSUR[LPDWHWKHWUXHODZRI PRWLRQRIWKHHFRQRP\DQGWKXVORZHUFHQWUDOEDQNORVV$VUHJDUGVWKHIUDFWLRQeWKH PRUHDJHQWVKDYHWRUHVRUWWRWKHPDFURHFRQRPLFSURMHFWLRQVSXEOLVKHGE\WKHFHQWUDO EDQNWKHKLJKHUWKHYDOXHVRIFHQWUDOEDQNORVVDQGWKHKLJKHUWKHJDLQIURPGLVFORVLQJWKH LQWHUHVWUDWHSDWK2QWKHRWKHUKDQGLWLVZRUWKQRWLQJWKDWVKRZLQJWKH,6DQG3&FXUYHV WRDOODJHQWVe ... argminUHDFKHGIRUK(. $JHQWVFDQFKRRVHGLIIHUHQWVDPSOHOHQJWKVRISDVWGDWDIRUWKHSXUSRVHRIOHDUQLQJ,Q the baseline scenario it is assumed that the learning sample smplVWUHWFKHVRYHUSHULRGV \HDUVZKLFKFRUUHVSRQGV  to the perpetual learning gain K ...

Ngày tải lên: 06/03/2014, 02:21

... decreasing agonist affinity and (b) promoting the agonist-induced active conformation due to the loss of a stabilizing constraint on the ground state of the receptor. Therefore, the agonist had a lower ... than the wildtype V 1a R but once the agonist bound, the receptor was more likely to signal. This dual role suggests that binding of the agonist releases the Arg46-mediated constraint on the ground ... which the N-terminus of the OTR is replaced with the corresponding sequence of the V 1a R [10]. The role of the N-terminus has been addressed recently by alanine-scanning mutagenesis of the N-terminus...

Ngày tải lên: 07/03/2014, 21:20