the discovery and conquest of mexico by bernal diaz

Anecdotes of the Habits and Instinct of Animals, by R. Lee potx

Ngày tải lên : 28/06/2014, 19:20

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Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx

Ngày tải lên : 15/02/2014, 13:20

... re-evaluation of the role of BCG vaccination in the prevention and control of TB in the United States. CDC, the Advisory Council for the Elimination of Tuberculosis (ACET), and the Advisory Committee ... Control and Prevention. The role of BCG vaccine in the prevention and control of tuberculosis in the United States: a joint statement by the Advisory Council for the Elimination of Tuberculosis and ... of the protective efficacy of BCG vaccines might have been affected by the methods and routes of vaccine administration and by the environments and characteristics of the populations in which BCG...

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Tài liệu Báo cáo khoa học: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid ppt

Ngày tải lên : 16/02/2014, 09:20

... or lysed and analysed for caspase 3 activity by measuring degradation of the Ac-DEVD-pNA peptide (right panel). The graphs represent average cell survival as a percentage of the control and the average ... The Authors Journal compilation ª 2010 FEBS 1325 The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the ... [16,17]. The BH3 domain-only proteins are a subfamily of the Bcl-2 family involved in the initiation of apoptosis through the mitochondrial pathway. The key event in the mitochondrial pathway is the...

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Báo cáo khoa học: Structure of the atrial natriuretic peptide receptor extracellular domain in the unbound and hormone-bound states by single-particle electron microscopy ppt

Ngày tải lên : 07/03/2014, 03:20

... in the absence of crystal Fig. 5. Overlay of the single-particle reconstructions in the absence (blue mesh) and presence (gold surface) of ANP. The reconstructions are rendered at 70% of the ... limited the resolution of the reconstruction to 22 A ˚ . Therefore, the reconstruction was low-pass-ﬁltered at this resolution. The hand- edness of the reconstructions was determined by comparison ... that the hh dimers, but not the tt dimers, represent the physiological structures. On the other hand, it has been proposed that the hh dimer and tt dimer structures both occur, and represent the...

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Báo cáo khoa học: Discovery and characterization of a Coenzyme A disulﬁde reductase from Pyrococcus horikoshii Implications for the disulﬁde metabolism of anaerobic hyperthermophiles doc

Ngày tải lên : 07/03/2014, 17:20

... reduction of the S. aureus enzyme there is loss of roughly 50% of the absorbance at 452 nm. In that case, the loss of absorbance is attributed to an asymmetric reduction of the dimeric enzyme, with the ... to determine the extinction coefﬁcient of the enzyme-bound FAD, the FAD was released from the holoenzyme by trichloroacetic acid (TCA) precipi- tation of the protein. The e 460 of the enzyme-bound FAD ... during addition of the ﬁrst equivalent of NADPH, while an increase is observed during the addition of the second and subsequent equivalents of NADPH. With the exception of the expected increase...

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Báo cáo khoa học: Investigation of the kinetics and order of tyrosine phosphorylation in the T-cell receptor f chain by the protein tyrosine kinase Lck potx

Ngày tải lên : 08/03/2014, 02:20

... tyrosine by assaying the transfer of 32 P by recombinant Lck on to each of the peptides. The rates of phosphorylation were found to depend on the location of the tyrosine, leading to the pro- posal ... exhibit the same kinetics as those located on the intact protein. Therefore, determination of the kinetics of phosphorylation of these peptides allows the order of phosphorylation of the six ... structure. The two groups of peaks at 6.85 and 7.15 p.p.m. correspond to the aromatic resonances of the seven tyrosines in the protein, and the inset 2D expansion of the 1 H- 1 H COSY shows that the...

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Project Gutenberg’s Philosophy and Fun of Algebra, by Mary Everest Boole This eBook is for the use pdf

Ngày tải lên : 15/03/2014, 00:20

... any energetic and continued action of one tends more or less to suppress the action of the others, for the time being, by drawing the blood from the organs which are the seat of them; and then, when ... meets the ANSI Standard Z39.48-1984. The production of this volume was supported in part by the Commission on Preservation and Access and the Xerox Corporation. 1990. BOUGHT WITH THE INCOME OF THE SAGE ... ounds of sugar at 3d. a pound. You multiply the six by the three. That is not because of any property of sugar, or of the copper of which the pennies are made. You would have done the same if the...

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The Wit And Humor Of America Volume Ii By Various, Marshall P. Wilder pdf

Ngày tải lên : 16/03/2014, 15:20

... stern worship of the unknown God, and acknowledged the deities of Athens. But the seal of their shame is their own smile at their early dreams, and the high hopes of their boyhood, their sneering ... pageant, and they are dragged hither and thither in it, are bled of their golden blood, and forced into a position they do not covet and which they despise. Then there are the inheritors of wealth. ... explained. They had been boys once, all of them, fresh and frank-hearted, and full of a noble ambition. They had read and pondered the histories of great men; how they resolved, and struggled, and...

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Báo cáo khoa học: A steady-state competition model describes the modulating effects of thrombomodulin on thrombin inhibition by plasminogen activator inhibitor-1 in the absence and presence of vitronectin ppt

Ngày tải lên : 23/03/2014, 17:21

... part of the reactive center loop of PAI-1 in the small cleft formed by the 60-loop and VR1 loop can be envisioned. The kinetics of the interaction of thrombin and TM were shown to be governed by ... stimulator of thrombin inhibition by these serpins, in line with the cofactor effect of TM on protein C activation. The exclusive function of the VR1 loop is now further supported by the results ... part of the effect of thrombin on the proliferation and migration of vascular SMC [4,34]. In the context of the vessel wall, TM might therefore function as a regulator of PAI-1 inactivation by...

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Updates in the Diagnosis and Treatment of Vasculitis Edited by Lazaros I. Sakkas and Christina Katsiari pptx

Ngày tải lên : 30/03/2014, 18:20

... VEGF and/ or Th17 and the extravasation and deposition of IgA by IL-6, TNF-α, VEGF, and Th2. The development of HSN could be related to the prevalence of underglycosylated polymeric IgA1, the effect ... glomerulonephritis. These reports represented key advances in our understanding of the pathogenesis of au‐ Updates in the Diagnosis and Treatment of Vasculitis34 cations for the amplification of the inflammatory ... state of the host contributes to the development of renal failure and injury of the inflamed tissue further modu‐ lates the inflammatory state of the host. One of the greatest obstacles to effective...

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Updates in the Understanding and Management of Thyroid Cancer Edited by Thomas J. Fahey doc

Ngày tải lên : 30/03/2014, 22:20

... in the thyroid gland. The effect of age is such significance in behavior and prognosis, that both the histologic diagnosis and the age of the patient are included in the staging system for these ... current understanding of the role of Insulin-like growth factors (IGFs) and their receptors in the pathogenesis of thyroid cancer and how expression of pIGF-IR may be an indicator of their clinical ... alters the mobility of the fluorescently labeled DNA and as such, affects the polarity of the emitted light by the fluorophor. Heterologously expressed p53 protein forms (wild-type and truncated)...

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ASSESSMENT OF THE ENVIRONMENTAL AND SOCIAL IMPACTS CREATED BY THE VLRC INDUSTRIAL RUBBER PLANTATION AND PROPOSED ENVIROMENTAL AND SOCIAL PLANS ppt

Ngày tải lên : 31/03/2014, 09:21

... affected by the Project. Loss of land and access to land The 33 villages impacted by the Project were found to have lost 83% of their agricultural lands. This major loss of land, and the loss of ... were harvesting their fields and some people were working at the VLRC at the time of the interview. The main topics of the consultations and interviews were about the land, and their different ... from the 28 th of September to the 7 th of October 2006 and was undertaken by a team of 5 persons in the 33 villages impacted by the Project. The second consultation took place from the 26 th ...

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Báo cáo Y học: The processivity and ﬁdelity of DNA synthesis exhibited by the reverse transcriptase of bovine leukemia virus pot

Ngày tải lên : 31/03/2014, 21:21

... chemotherapy of AIDS [2,10,11]. Targeted drug d esigns rely on a better understanding of the structure and function of retroviral RT. Therefore, the investigation of RT of other retroviruses should expand ... no further extension by misincorporating A opposite to G. This is in contrast with the pattern of elongation observed here with HIV-1 and MLV RTs (Fig. 3) and previously by these RTs and the RTs of ... sets of primer-extension reactions were carried out and analysed. In each case, we used increasing concentrations of a single dNTP, thereby determining the standing-start rate of synthesis of the correct...

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believing by faith an essay in the epistemology and ethics of religious belief may 2007

Ngày tải lên : 11/06/2014, 05:31

... with the aim of ‘disambiguating’ either for or against theism. Fifth, the question arises whether stepping outside the mainstream by accepting evidential ambiguity requires the defender of the ... truth in their practical reasoning will then influence their action and the decision-theoretic apparatus using the notion of expected utility is a way of making precise the operation of this influence. ... as best they can of the moral probity of their ventures in faith, reflective believers will therefore need to integrate those commitments with their best theories of how the world both is and morally...