the diagnostic gold standard of the viral
báo cáo hóa học:" Of gastro and the gold standard: evaluation and policy implications of norovirus test performance for outbreak detection" ppt
Ngày tải lên :
18/06/2014, 15:20
... identification of NVG as the etiology of an outbreak may contribute to the understanding of the burden and epidemiology of these infections, pinpoint the outbreak source, and rule out other AGE etiologies ... In summary, the absence of a traditional "gold standard" for the evaluation of test characteristics in the identification of NVG outbreaks does not preclude rational evaluation of the test characteristics ... for a gold standard test; this approach should provide unbiased estimates of test characteristics for, as stated by Pepe, "the definition of disease is not dependent on the results of the diagnostic...
- 9
- 449
- 0
báo cáo hóa học:" Is tension band wiring technique the "gold standard" for the treatment of olecranon fractures? A long term functional outcome study" docx
Ngày tải lên :
20/06/2014, 01:20
... minimal loss of physical capacity The technique remains the "gold standard" for the treatment of displaced and minimally comminuted olecranon fractures despite the introduction of new Page of (page ... Page of (page number not for citation purposes) Journal of Orthopaedic Surgery and Research 2008, 3:9 Statistics The microsoft excel program was used for the creation of the graphs and the SPSS ... osteosynthesis was achieved with the insertion of two parallel 1.8 mm Kirschner wires from the tip of the olecranon and a 18 gauge wire in a figure -of eight fashion Major intraoperative goal was the...
- 6
- 492
- 0
METFORMIN – MORE THAN ‘GOLD STANDARD’ IN THE TREATMENT OF TYPE 2 DIABETES MELLITUS
Ngày tải lên :
12/07/2015, 15:49
... MORE THAN GOLD STANDARD IN THE TREATMENT OF TYPE DIABETES MELLITUS DISCOVERY OF METFORMIN The work of Dr Jean Sterne, a French clinician and his colleagues led to the discovery of metformin ... glucose levels by further 5%, raising the incidence of gastrointestinal side effects The risk of hypoglycemia was low, almost the same as in the placebo group (8) Lactic acidosis is the most dangerous ... on insulin therapy compared with intensification of the insulin dose by 20% resulted in lower body weight, lower body mass index, insulin dose and HbA1c at the end of the study in the metformin...
- 10
- 420
- 0
Tài liệu Báo cáo khoa học: Glycomics-based analysis of chicken red blood cells provides insight into the selectivity of the viral agglutination assay docx
Ngày tải lên :
14/02/2014, 19:20
... measurement of various concentrations of solutions can then be used to quantify viral titer Additionally, the introduction of antisera capable of neutralizing a viral strain reduces the ability of virus ... cRBCs Defining the glycans present on the surface of cRBCs will allow either for the design of strategies to optimize the agglutination assay or the design of alternative strategies for the detection ... by the label and independent of the attributes of the glycan to which it is attached Accordingly, we aimed to determine the amount of individual cRBC glycans by HPLC through the use of a standard...
- 14
- 811
- 0
Báo cáo khoa học: "A Comprehensive Gold Standard for the Enron Organizational Hierarchy" potx
Ngày tải lên :
07/03/2014, 18:20
... G to be the set of pairs in the gold standard such that the people involved in the pair in T communicate with each other These are precisely the dominance relations in the gold standard which ... calculate the degree centrality of every node in the email exchange network, and then rank the nodes by their degree centrality Recall that the degree centrality is the proportion of nodes in the network ... directionality of the dominance relation of people given they are in a hierarchical relation,1 the random baseline for our task performs at 50% We have 13,724 such pairs of people in the gold standard...
- 5
- 443
- 0
Báo cáo khoa học: Binding of the viral immunogenic octapeptide VSV8 to native glucose-regulated protein Grp94 (gp96) and its inhibition by the physiological ligands ATP and Ca2+ Ming Ying and Torgeir Flatmark pot
Ngày tải lên :
30/03/2014, 11:20
... 2C), and the response isotherm gave a [A]0.5 of 168 lm Although Grp78 ⁄ BiP and Grp94 are the two major recipients of the pool of ATP translocated into the lumen of ER [24] the effects of ATP binding ... equilibrium-binding isotherms obtained in the absence of ATP ⁄ Ca2+ (d), in the presence of 500 lM ATP (.) and in the presence of 500 lM Ca2+ (s) in the flow buffer FEBS Journal 273 (2006) 513–522 ª 2006 The Authors ... Mr,ligand are the relative molecular mass of the analyte and ligand, respectively; n is the number of analyte-binding sites on the protein; (A) is the fraction of active sites on the immobilized...
- 10
- 304
- 0
MORAL PREJUDICE AND AESTHETIC DEFORMITY: REREADING HUME''''S "OF THE STANDARD OF TASTE" pptx
Ngày tải lên :
30/03/2014, 16:20
... that in the case of works from alien cultural contexts, the true judge adopts the point of view of the intended audience, making allowance for their prejudices However, in the final pages of the ... not of the urgency of what I interpret as Hume’s attempt, in the final pages of the essay, at a taxonomy of prejudices, or so I shall now argue III A TAXONOMY OF PREJUDICE In the final pages of the ... with the demands of the here and now, hence the cultural relativism of these concluding remarks in his essay.”20 Each of these readings is unsatisfying First, the fact that the paradox of taste...
- 13
- 436
- 0
Báo cáo hóa học: " Abstract Despite new additions to the standard of care therapy for high grade primary malignant brain tumors, the prognosis for patients with this disease is still poor." ppt
Ngày tải lên :
18/06/2014, 16:20
... that the overall number of open trials is encouragingly higher However, while the number of cellular therapy trials remained the same, the clear trend was towards an increase in the number of vaccine ... and quality of life to become integrated into the standard of care regime [5,52-54] The number of slots open for patient accrual to the immunotherapy protocols contained in our list of open trials ... accompanying support by the National Institutes of Health will be critical Furthermore, standardization of the immunologic monitoring endpoints would also help advance the immunotherapy field Centralized...
- 10
- 589
- 0
The Impacts of Farmer Cooperatives on the Standard of Living Of Cocoa Producing Villages in Côte d’Ivoire and Ghana pptx
Ngày tải lên :
27/06/2014, 15:20
... from the regional cooperative office Although they had had a substantial amount of beans on their own, which represented the majority of the sales of coca in the whole society, they had to take their ... column the number of households who responded to the variable in question Column then reports the "mean value" of such responses; and column the absolute variability in the form of the "standard ... cooperative in the whole region, was founded in 1968 Since 1991, they renamed themselves the Union of Cooperatives because there are so many separate units below them The members of the cooperative...
- 88
- 1.8K
- 0
Báo cáo sinh học: "India''''s ''''gold mine'''' of ancestral bacilli and the looming TB-HIV pandemic" potx
Ngày tải lên :
08/08/2014, 19:20
... to muster the support of several scientific organizations, attention of the policy makers, and finally of politicians before his idea of European CDC was approved in April 2004 under the new European ... and support Research in the laboratory of Niyaz Ahmed is supported through CDFD core grants (from the Department of Biotechnology, Government of India), Indian Council of Medical Research (Indo- ... Control and Prevention (CDC), of the USA A European equivalent of CDC has been recently shaped in Stockholm, thanks to the efforts championed by Michel Tibayrenc, from the IRD in Montpellier, France...
- 2
- 271
- 0
Báo cáo y học: " Does the viral subtype influence the biennial cycle of respiratory syncytial virus?" pptx
Ngày tải lên :
12/08/2014, 04:20
... principally in the structure of the G or N proteins of the virus We undertook this study to determine if the circulation of different subtypes might explain the biennial pattern of RSV epidemics ... than 12 months of age than in females of the same age, while the frequency of infection with the two subtypes became equal in the two genders after 12 months of age Our previous study of RSV activity ... as part of the scientific project #0005002, approved by the ethics committees of the Croatian National Institute of Public Health (CNIPH), the University Children's Hospital Zagreb and the University...
- 7
- 321
- 0
Báo cáo khoa học: " Does the viral subtype influence the biennial cycle of respiratory syncytial virus?" potx
Ngày tải lên :
12/08/2014, 04:20
... principally in the structure of the G or N proteins of the virus We undertook this study to determine if the circulation of different subtypes might explain the biennial pattern of RSV epidemics ... than 12 months of age than in females of the same age, while the frequency of infection with the two subtypes became equal in the two genders after 12 months of age Our previous study of RSV activity ... as part of the scientific project #0005002, approved by the ethics committees of the Croatian National Institute of Public Health (CNIPH), the University Children's Hospital Zagreb and the University...
- 7
- 214
- 0
Báo cáo khoa học:" Effective suppression of Dengue fever virus in mosquito cell cultures using retroviral transduction of hammerhead ribozymes targeting the viral genome" docx
Ngày tải lên :
12/08/2014, 04:21
... stability of the hRz within the cellular environment, (ii) colocalization of the hRzs to the target RNA [22,23] and (iii) accessibility of the hRzs to the cleavage site within the context of RNA ... determine the level of specificity of the ribozyme In this study, the length of each arm ranges from 5–10 bp The sequences of hRz templates, positions of the triplets on DENV genome, and the specific ... expression and translocation of the hRzs to the cytoplasm, and a stretch of 60As is attached to the 3' end of the hRz sequence for recruitment of RNA helicase Page of 17 (page number not for citation...
- 17
- 233
- 0
Báo cáo y học: " Efficacy of salmeterol/fluticasone propionate by GOLD stage of chronic obstructive pulmonary disease: analysis from the randomised, placebo-controlled TORCH study" ppsx
Ngày tải lên :
12/08/2014, 14:20
... about the effectiveness of these agents in patients with GOLD stage II COPD, with the robustness of any clinical conclusions drawn being limited by the relatively small size of the subgroups reported ... report, May 2009 Data on file] and the demographics of the TORCH GOLD stage II population is also similar to that of the UPLIFT clinical trial [10] The majority of patients were also sufficiently ... the use of ICS-containing therapy [2] and whilst this was observed, the probability of pneumonia with SFC in GOLD stage II patients was lower than that observed in the overall population Further...
- 9
- 332
- 0
Báo cáo y học: " Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR" pdf
Ngày tải lên :
13/08/2014, 05:20
... for the addition/removal of covalent modifications on the histone tails [35-37] In the case of retroviruses, the integration of proviral DNA into the genome of an infected cell requires the manipulation ... "off" of the HIV-1 LTR Therefore, future experiments will determine the rate and type of Tat methylation on the LTR and in the presence of TAR RNA Although we have shown that the lysine 51 of ... transactivation [55-59] The acetylation of these residues is of great interest as a target for inhibition therapies; the prevention of acetylation would ensure only a low level of viral DNA is transcribed...
- 13
- 113
- 0
Báo cáo y học: "Recovery of fitness of a live attenuated simian immunodeficiency virus through compensation in both the coding and non-coding regions of the viral genome" pot
Ngày tải lên :
13/08/2014, 05:22
... in the of leader RNA secondary structure SIVSL1 and position of the SD2RNA secondary structure of SL1 and position of the SD2-nucleotide deletion in the SIV leader Secondary structure of the ... cells Mutant viral RNA was extracted from aliquots of the supernatants of these transfections and normalized on the basis of p27-CA To assess relative packaging efficiency, mutant viral RNAs were ... we tested the ability of the two NC mutations to rescue vRNA dimerization Figure 3C shows that the SD2 variant did have slightly increased levels of dimeric RNA in the presence of either E18G...
- 10
- 213
- 0
Báo cáo y học: "Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway" pot
Ngày tải lên :
13/08/2014, 06:20
... stimuli [11-13] However, in spite of the relevance of these reservoir cells in the control of viral persistence, the mechanisms responsible of apoptosis resistance of persistently-infected cells ... independent of the magnitude of viral replication Apoptosis resistance is independent of the magnitude of viral replication A) Jurkat and J1.1 cells were incubated in the presence or absence of 1000 ... independent of the magnitude of viral replication Apoptosis resistance of HIV persistenly-infected cell lines involves modulation of the mitochondrial pathway In order to dissect the mechanisms...
- 12
- 250
- 0
Báo cáo y học: " Trans-inhibition of HIV-1 by a long hairpin RNA expressed within the viral genome" pps
Ngày tải lên :
13/08/2014, 09:20
... inhibition, the use of both approaches as therapeutic antiviral is limited because of the rapid emergence of HIV-1 escape mutants [9-11] Strategies to reduce the chance of viral escape include the simultaneous ... 93 nt deletion in the 5' region of Nef and a 300 bp inverted repeat within the Nef gene (Fig 1) The construction of the HIV-lhNef mutant and the generation of molecular clones of HIV-lhNef escape ... in a dramatic drop of the viral transduction titer, possibly also due to self-targeting of Nef/LTR sequences in the vector genome Unlike the non-replicating lentiviral vector, the HIV-lhNef virus...
- 14
- 348
- 0
Báo cáo y học: "Use of a multi-virus array for the study of human viral and retroviral pathogens: gene expression studies and ChIP-chip analysis" pot
Ngày tải lên :
13/08/2014, 13:20
... listing the identity of the PCR primers used for the production of the amplicons, their exact coordinates on the genomes, the sizes of the probes generated and the success of the amplification Also ... to amplicons of other viruses, only two (proviral LTR and nef) of the 11 spotted regions of the HIV-1 genome hybridized to the DNA sample The G/C content of the entire coding region of HIV is 42% ... both the experimental and control and the ratio of these was used as a scaling factor to adjust the values of all fluorescence measures for the viral genes represented on the array For the expression...
- 15
- 376
- 0