... discussed in this paper, there is also evidence that diabetes can induce or aggravate ER stress and thereby affect the complications of diabetes, such as renal disease, retinopathy and vascular ... degradation (ERAD), and degraded by the proteasome As a major intracellular calcium storage compartment, the ER also plays a critical role towards maintenance of cellular calcium homeostasis In addition, ... and (3) activation of the ER localized cysteine protease, caspase 12 Caspase 12 is activated by m-Calpain in the cytoplasm Activation of m-Calpain is a consequence Ca2? efflux out of the ER upon
Ngày tải lên: 02/11/2022, 09:29
... that indicates the quality of a certain set of vocational activities is of interest, rather than a mere test score Assessment Design The design of a vocational learning progression requires either ... (group 2) Theoretical and Educational Significance Vocational development on an aggregate level in the economic domain largely depends on a combination of two aspects: the acquisition of a set of principles ... globally active industrial enterprise having their head office in Aachen, Germany The company is involved in the production of ceramic goods, such as china and porcelain for tableware and vases
Ngày tải lên: 02/11/2022, 14:24
def (digestive organ expansion factor) is a crucial gene for the development of endoderm derived organs in zebrafish (danio rerio
... 1140311408. Kawakami, K., Takeda, H., Kawakami, N., Kobayashi, M., Matsuda, N., and Mishina, M. (2004). A transposon-mediated gene trap approach identifies developmentally regulated genes in zebrafish. ... in the major pathway of beta-cell formation in the pancreas. Development 127, 5533-5540. Sawa, C., Yoshikawa, T., Matsuda-Suzuki, F., Delehouzee, S., Goto, M., Watanabe, H., Sawada, J., Kataoka, ... Identification of a functional transposase of the Tol2 element, an Ac-like element from the Japanese medaka fish, and its transposition in the zebrafish germ lineage. Proc Natl Acad Sci U S A 97, 1140311408.
Ngày tải lên: 11/09/2015, 16:06
báo cáo hóa học: " Cognitive interviewing methodology in the development of a pediatric item bank: a patient reported outcomes measurement information system (PROMIS) study" docx
... the conceptualization and operationalization of this research prior to his death. This work was funded by the National Institutes of Health through the NIH Roadmap for Medical Research, Grant ... the clarity and ration- ale of the directions, the meaning of the items, the appro- priateness of the response choices, and overall comments on the relevance and complexity of the questionnaire ... years could respond to items and talk about all aspects of their health and well-being in meaningful ways. They are able to comprehend varying response options on a categorical scale, and can accurately
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học: " The development of postural strategies in children: a factorial design study" doc
... values and standard deviation is shown Statistical Analysis All PPs were analyzed through a two-way ANOVA, with vision (EO vs EC) and age as factors Each condition was then separately analyzed ... experimental evidence, i.e the behaviour of parameters object of the analysis Using the Mean Amplitude as an example, Figure shows how, after Tset, the actual value of the parameter does not remarkably ... on the force plate is crucial: the majority of the parameters used to define the postural ability are summary measures, and their application is based on the assumption of stationarity, in that
Ngày tải lên: 19/06/2014, 10:20
báo cáo hóa học: " TLR3 signaling is either protective or pathogenic for the development of Theiler''''s virus-induced demyelinating disease depending on the time of viral infection" docx
... 5’-CAACGAGCCACATATGCGGATTAC-3’); IL-1β, (5’-TCATGGGATGATAACCTGCT-3’ and 5’-CCCATACTTTAGGAA- GACACGGAT-3’); IFN-α, (5’-ACCTCCTCTGACCCAGGAAG -3’ and 5’-GGCTCTCCAGACTTCTGCTC-3’); IFN-β, (5’-CCCTATGGAGATGACGGAGA-3’ ... (5’-CCCTATGGAGATGACGGAGA-3’ and 5’-CTGTCTGCTGGTGGAGTTGA-3’); IFN-γ, (5’-ACTGGCAAAAGGATGGTGAC-3’ and 5’-TGAGCTCATTGAATGCTT GG-3’); IL-10, (5’-GCCAAGCCTTATCGGAAATGATCC-3’ and 5’-AGACACCTTGGTCTTGGAGCTT-3’); ... (5’-CTGTGAAGGGAATGGGTGTT-3’ and 5’GGTCACTGTCCCAGCATCTT-3’); IL-6, (5’-AGTTGCCTTCTTGGGACTGA-3’ and 5’TCCACGATTTCCCAGAGAAC-3’); IL-17, (5’-GGGGATCCATGAGTCCAGGGAGAGC-3’ and 5’-CCCTCGAGTTAGGCTGCCTGGCGGA-3’);
Ngày tải lên: 19/06/2014, 22:20
Báo cáo y học: "The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus" ppt
... erythematosus (SLE) is a disease characterized by the production of a variety of auto-antibodies against ubiquitous intracellular and cell surface antigens Detailed analysis of these autoantibodies ... units (AEU) relative to a standard positive sample that was assigned a value of 100 AEU The data are presented as mean ± standard error of the mean Statistics were performed comparing autoantibody ... in the level of circulating DNA was observed in ash.DNase I transgenic mice These data demonstrate that the therapeutic use of a recombinant actin-resistant, salt-resistant and hyperactive DNase
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Looking through the ''''window of opportunity'''': is there a new paradigm of podiatry care on the horizon in early rheumatoid arthritis" pot
... to the application of specialist skills to manage localised, residual disease activity and associated functional impairments. Here we describe a new paradigm of podiatry care in early RA. This ... guidelines for the management of early rheumatoid arthritis [72] Multidisciplinary team care Podiatry is part of the multidisciplinary team Podiatry is part of the multidisciplinary team Full-time ... School of Health, Glasgow Caledonian University, Cowcaddens Road, Glasgow G4 0BA, UK Full list of author information is available at the end of the article Woodburn et al. Journal of Foot and Ankle
Ngày tải lên: 10/08/2014, 21:24
báo cáo khoa học: "Is the involvement of opinion leaders in the implementation of research findings a feasible strategy?" doc
... General practitioners Ischaemic heart disease Practice nurses Ischaemic heart disease Practice managers N /A Secondary care Physicians Ischaemic heart disease Surgeons Laparoscopic surgery Medical ... Please read each of the paragraphs and write in the names of up to three colleagues that best fit the description of each characteristic. The same person may be named for more than one characteristic. ... many years, the traditional approach to dissemination has been the publication of research findings in journals (or other media), which the target audience is likely to read, in the belief that
Ngày tải lên: 11/08/2014, 05:21
Báo cáo y học: " The development of a knowledge test of depression and its treatment for patients suffering from non-psychotic depression: a psychometric assessment" ppt
... episode of clinical depression, there is an increased risk of a second episode a The risk is very minimal c Maintenance treatment can reduce the chances of relapse b The risk is between 15% and ... conceived of the study and participated in its design and coordination AG administered the instruments and collected the data CV directed and oversaw the statistical analysis which was conducted ... Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary AB T2N 4N1, Canada Email: Adel Gabriel* - gabriel@ucalgary.ca; Claudio Violato - violato@ucalgary.ca * Corresponding author
Ngày tải lên: 11/08/2014, 17:20
Báo cáo y học: " Role of lysophosphatidic acid receptor LPA2 in the development of allergic airway inflammation in a murine model of asthma" potx
... 5'-AAGCTGAGTAACGGGCAGAC-3' LPA3 Forward: 5'-ATTGCCTCTGCAACATCTCG-3' Reverse: 5'-ATGAAGAAGGCCAGGAGGTT-3' LPA4 Forward: 5'-ACTGCGTTCCTCACCAACAT-3' Reverse: 5'-CGATCGGAAGGGATAGACAA-3' LPA5 Forward: ... supports the notion of LPA as a chemotaxis factor of inflammatory cells in allergic inflammation The source of LPA accumulation and mechanism(s) of LPA generation in the lung after allergic inflammation ... 5'-GCTCCAGTGCCCTGACTATC-3' Reverse: 5'-CAGAGCGTTGAGAGGGAGAC-3' COX-2 Forward: 5'-CCCCCACAGTCAAAGACACT-3' Reverse: 5'-GGCACCAGACCAAAGACTTC-3' Page of 12 (page number not for citation purposes) Respiratory
Ngày tải lên: 12/08/2014, 14:20
Báo cáo y học: " Construction of doxycyline-dependent mini-HIV-1 variants for the development of a virotherapy against leukemias" pps
... Center of the University of Amsterdam, Amsterdam, The Netherlands Email: Rienk E Jeeninga - r.jeeninga@amc.uva.nl; Barbara Jan - janbarbara@hotmail.com; Henk van den Berg - h.vandenberg@amc.uva.nl; ... AAA GGA CCA GCA AAG CTC CTC TGG AAA GGT 3') and WS3 (5'TAG AAT TCA AAC TAG GGT ATT TGA CTA AT). The same PCR was per- formed on DNA from a vpU-deletion construct [pDR2484, [39]]. The ... MEPVDPRLEPWKHPGSQPKTACTTCYCKKCCFHCQVCFTTKALGISYGRKKRRQRRRPPQGSQTHQVSLSK NL4-3 N M AH.N A HIV-rtTA A rtTAΔ6 A N M AH.N A rtTAΔ7 A A M AH.N A rtTAΔ6 B N M AH.N A rtTAΔ7 B A M AH.N A U3nefvpUvpRviftatTAR ΔΔΔΔΔ+- rtTAΔ6 A rtTAΔ6 B A B 26 711 ΔΔ-ΔΔ+-
Ngày tải lên: 13/08/2014, 09:20
Báo cáo y học: "The specificity and the development of social-emotional competence in a multi-ethnic-classroom" pptx
... Disap- pearance, The Departure, The Return of the Parents, The Lost Key, The Exclusion, The Mother's Headache, Three is a Crowd, and The Sand Castle. The warm up story is a beginning of a ... in the classroom differed in moral reasoning at the beginning of the kindergarten year. A moral approach was utilized the most by the Latin- American children and the least by the Asian-American ... emotions in their narratives than at the begin- ning of the kindergarten year. The Asian-American chil- dren increased and the Latin-American children decreased the avoidance of conflicts over the course
Ngày tải lên: 13/08/2014, 18:21
Báo cáo y học: "Lack of recovery in monocyte human leukocyte antigen-DR expression is independently associated with the development of sepsis after major trauma" ppsx
... multivariate logistic regression analysis indicated that low mHLA-DR expression was independently associated with the development of sepsis, whereas all the other parameters included in the analysis ... Utility of activated partial thromboplastin time waveform analysis for identification of sepsis and overt disseminated intravascular coagulation in patients admitted to a surgical intensive care ... Belgium) was used to perform the sta- tistical analyses. Results Patients’ characteristics A total of 536 consecuti ve patients in the early stages of trauma were admitted to the trauma ro om between
Ngày tải lên: 14/08/2014, 07:21
the evolution of banking; a study of the development of the credit system (1915)
... as the crop harvested the present year (1914) was the largest in our The failure of the State Banks before war was caused primarily by the inability of the banks to redeem their ... circulating notes in gold and silver on demand as agreed It was not caused b}^ the redundancy of the notes history the as is so often... the earth was flat and stationary But the Copernican ... Copernican theory of the revolution of the earth upon its axis each twenty-four hours, and its yearly, journey around the sun, cleared away the mists of ignorance that surrounded the
Ngày tải lên: 05/11/2014, 10:07
Thai Literature at the Crossroads of Modernity Advancing a Critique of Neo-liberal Development through the Writings of Khamsing Srinawk and Chart Korbjitti
... frequently repeated mantra that to be Thai is to trust in nation, religion, and monarchy (chaat, satsanah, mahakaset) The traditional values of Thai. .. breakdown of the traditional family ... what ways do the writings of Khamsing and Chart provide insight into the shortcomings of globalization and/or the failings of Thailand’s development agenda that are not apparent in the statistical ... Globalisation, and Crisis: The Case of Thailand (2000), Laird compiles a list of the effects of neo-liberal policies worldwide and in Thailand: capitalists to make huge profits
Ngày tải lên: 14/05/2015, 12:09
Application of PEEC modeling for the development of a novel multi gigahertz test interface with fine pitch wafer level package
... capacitance is evaluated for different geometries and material properties Then transmission characteristics of a multilayered coupled micro-strip filter are analyzed The treatment of ... NATIONAL UNIVERSITY OF SINGAPORE 2005 APPLICATION OF PEEC MODELING FOR THE DEVELOPMENT OF A NOVEL MULTI-GIGAHERTZ TEST INTERFACE WITH FINE PITCH WAFER LEVEL PACKAGE BY JAYASANKER JAYABALAN ... simultaneously the set of Equations (D.9) and (D.14) using equations (D.10-D.14), we can calculate the Fermi energy and then W(EF). The capacitance C is represented by that of a “needle” in the shape of a
Ngày tải lên: 11/09/2015, 14:24
Tài liệu RESULTS BASED MANAGEMENT IN THE DEVELOPMENT CO-OPERATION AGENCIES: A REVIEW OF EXPERIENCE docx
... agency, as well as the donor country’s parliament and taxpayers. Within the implementing agency, as the level of management changes, the level of detail of the indicators may change. A field manager, ... indicators of development results and provide space for explanation and justification of the ratings. The information from these forms are entered into a central database and analyzed in the Bank’s ... of the new areas of work identified was performance management systems. The DAC Secretariat agreed to lead and co-ordinate the work. The topic of performance management, or results based management,...
Ngày tải lên: 21/02/2014, 11:20
Báo cáo " The development of financial systems of ASEAN-5 and Vietnam: A comparative analysis " potx
... As far as the development of financial scale is concerned, the ASEAN-5 financial systems were about ten times as large, with the total financial assets of 80% of GDP on average. In Vietnam, ... paper looks at the development of the financial systems of ASEAN-5 countries and Vietnam. By making a comparison between factors that foster the financial development of ASEAN-5 and Vietnam, ... by the Basel I ratios of regulatory capital to risk-weighted assets and the ratio of market capital to risk-adjusted assets) could reflect the financial position of banks. As regards the capital...
Ngày tải lên: 14/03/2014, 17:20
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