... disorders, cancer and atherosclerosis [5,6], as a result of its antiproliferative, anti-inflammatory and anti-oxidant effects [7–9] DHEA is a powerful inhibitor of carcinogenesis, in the early- and late-progression ... 25 and 55 years old, and it is the second most common cause of death from cancer among Mexican women [21] Therefore, the aim of this work was to evaluate the effect of pharmacological doses of ... and late apoptosis than C33A cells (Table 2) These results indicate that DHEA can induce early and late apoptosis and also necrosis Discussion DHEA is an intermediate in the biosynthesis of androgen...
Ngày tải lên: 16/03/2014, 00:20
... monomers and acidic organelles When the extrameiotic products (Fig 2A) and the parental macronucleus (Fig 2C and D) began to degenerate, they were stained in yellow (merged colour of green and orange), ... (lanes 6, 7, and 8, respectively), and 0.1, 1, and mM ZnCl2 (lanes 9, 10, and 11, respectively) were assayed at 30 °C for 120 A standard reaction (S) was performed with 50 mM Mops (pH 6.5) and ... requirement of the mitochondrial nuclease activity Reaction mixtures that contained 50 mM Mops (pH 6.5) and 10 mM KCl, together with 1, 5, and 10 mM MgCl2 (lanes 3, 4, and 5, respectively), 1, 5, and...
Ngày tải lên: 20/02/2014, 03:20
Báo cáo khoa học: Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide attenuate the cigarette smoke extract-induced apoptotic death of rat alveolar L2 cells ppt
... upstream of, the apoptotic cascade and loss of membrane integrity Thus, it has been shown that the stimulation of inflammatory-related enzymes and caspases is involved in the cytotoxicity of CSE, and ... to play an important role in the toxicity and in the effects on inflammatory-immune processes of cigarette smoke There are many ROS inducers among these toxic components, and they cause the oxidative ... significantly the CSE-evoked activation of both MMPs and caspase-3 Furthermore, it has been suggested that the deactivation of CSE-stimulated MMPs and caspase-3 was one of the possible mechanisms...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: Soluble recombinant CD69 receptors optimized to have an exceptional physical and chemical stability display prolonged circulation and remain intact in the blood of mice doc
... CD69NG70 (lanes and 5), CD69NV82 (lanes and 7) CD69NS84 (lanes and 9), rat CD69 (lanes 10 and 11) and mouse CD69 (lanes 12 and 13) was performed under nonreducing (even lanes) and reducing (odd lanes) ... in the solubility and stability among these proteins and allow us to select the human protein containing amino acids Gly70 to Lys199 (and the rat and mouse orthologs) as the most physically and ... Moreover, the exclusion of the protein in urine and faeces, and uptake by the liver, was relatively low On the other hand, the least stable human CD69NS84 protein displayed a rapid plasma clearance...
Ngày tải lên: 16/03/2014, 04:20
The Last Judgment: Michelangelo and the Death of the Renaissance
... course of humanity, the rabble who could never understand his feelings and who projected their own prejudices on others, because they could not understand the glory of the human soul and the majesty ... ghosts of men, and all they cared about was food, wine, women, and gold The emperor’s army attacked Rome from the west, between the walls of the Vatican and the Janiculum hill, just south of the ... all the news He stayed in the house of Gianfrancesco Aldrovandi, a lover of Florentine culture Aldrovandi made Michelangelo read from Petrarch and Dante every night before he fell asleep, and the...
Ngày tải lên: 16/03/2014, 11:21
the accidental death of an anarchist
... important political themes and performance techniques to both entertain and inform his audience Accidental Death of an Anarchist creatively uses a comic, grotesque and satirical style to avoid any ... By breaking down the fourth wall, the audience becomes co-conspirators, and part of the political conspiracy Through the Maniac's exaggerated and comic view of the court system, the responder also ... slaps and kicks the police officers This is an unexpected thing for the audience to see and so it adds to the humour Fo also uses satire in real situations and characters to present his view of the...
Ngày tải lên: 21/03/2014, 22:52
Cinema and Soviet Society from the Revolution to the Death of Stalin potx
... Aleksandr Serafimovich (the future author of The Iron Flood) and Maiakovsky tried their hand at working for movies, but they had little experience and understanding of the special needs of the ... on the basis of the work of a few outstanding directors but on the basis of the films of dozens of others, many of whom were talented and able people, but less ambitious and innovative that the ... sorcerer The child dies and the unhappy couple break up By contrast, the other family, which observes the advice of the doctor and appreciates the importance of cleanliness have a healthy child and the...
Ngày tải lên: 30/03/2014, 14:20
death of a generation how the assassinations of diem and jfk prolonged the vietnam war
... Debian, the real heart and soul behind Debian is the community These men and women spend their free time working on the code with an understanding that the software is shared freely around the ... MATERIALS THE ACCURACY AND COMPLETENESS OF THE INFORMATION PROVIDED HEREIN AND THE OPINIONS STATED HEREIN ARE NOT GUARANTEED OR WARRANTED TO PRODUCE ANY PARTICULAR RESULTS, AND THE ADVICE AND STRATEGIES ... Stopping the System Using the reboot, halt, and poweroff commands Using the shutdown command Working with the Filesystem and Related Commands Mounting drives...
Ngày tải lên: 01/06/2014, 00:39
Welcome to the Creative Age - Bananas, Business and the Death of Marketing
... research? The brand and the snake-oil salesmen Problem 1: brand gets in the way of the real problems Problem 2: the claims made for the importance of the brand are overblown Problem 3: the brand ties ... and ‘strategy’; endless incantation of the mantra of brands, branding and brand values Hours are spent dissecting the nuances of focus groups and tracking studies6 – looking for indications of ... for the offer and its acceptance and how the acceptance becomes another offer and so on Exhilarating! Sit in your next meeting and listen for the offers And watch what happens when you take them...
Ngày tải lên: 06/06/2014, 08:44
Báo cáo khoa học: "The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation" pot
... contributed to the design of the study VJ performed conception and design of the study and substantially contributed to interpretation of data, drafting and critical revision of the manuscript and final ... chemotherapy and radiotherapy, these lipophilic drugs target cellular membranes and interfere with membrane lipid composition and the formation of lipid second messengers, thereby affecting the ... the results from the WST-1 test and flow cytometry may be due to the high standard deviations in the WST-1 test that would preclude the detection of a small combination effect On the other hand,...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo y học: " b-Lapachone induces heart morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafish embryo" docx
... Cheng for their helpful discussions and advice The authors thank Ms Wun-Hsiang Yu for her maintenance of the fish room We thank the Core Facility of the Institute of Cellular and Organismic Biology, ... treatment induces the death of erythrocytes and endocardium Embryos at 24 hpf were treated with either DMSO or blapachone for h and then fixed at 30 and 48 hpf to analyze the presence of erythrocytes ... system Materials and methods Fish maintenance and collection of embryos Adult zebrafish (Danio rerio) were raised at the zebrafish facility of the Institute of Cellular and Organismic Biology,...
Ngày tải lên: 10/08/2014, 10:20
Báo cáo y học: " Chitosan can stop or postpone the death of the suckling mice challenged with foot-and-mouth disease virus" docx
... 0.1 ml of the chitosan granules (contain 0.5 mg) and 0.1 ml of O/ CHN/99 strain at the same time, and other ten suckling mice were only injected 0.1 ml of O/CHN/99 strain as the control The death ... immunostimulants 20 years ago due to its harmless, biodegradable, biocompatible, abundant and anti- antimicrobial And now, chitosan is widely used in human and veterinary medicine [4] The data showed ... particles of chitin and chitosan (but not their soluble analogues) increase the generation of active oxygen species in mouse (Mus musculus L.) alveolar macrophages and induce the synthesis of γ-interferon...
Ngày tải lên: 12/08/2014, 04:20
Báo cáo y học: "Alterations of alveolar type II cells and intraalveolar surfactant after bronchoalveolar lavage and perfluorocarbon ventilation. An electron microscopical and stereological study in the rat lung" pdf
... conception of the study and the data interpretation, and revised the manuscript critically MO has made substantial contribution to the conception and design of the study; organized, performed and supervised ... the analysis and interpretation of the data WB contributed to the conception and design of the study, performed the animal experiments and revised the manuscript carefully RRW contributed to the ... calculated the data and made substantial contribution to the analysis and interpretation of the data LK performed the histological analysis, calculated the data and made substantial contribution to the...
Ngày tải lên: 12/08/2014, 15:20
Báo cáo y học: "Steppingstones to the implementation of an inhospital fracture and dislocation registry using the AO/OTA classification: compliance, completeness and commitment" docx
... fractures of the pelvic ring and the acetabulum, fractures and dislocations of the face, head, neck, complex fractures of the hand and some of the fractures of the thoracic and lumbar spine) The primary ... accuracy of the register and contributed to data extraction and writing KH made the operation planning program; ORPlan and contributed to the data extraction AJA contributed in the planning and participated ... to the implementation of an inhospital fracture and dislocation registry using the AO/OTA classification: compliance, completeness and commitment Scandinavian Journal of Trauma, Resuscitation and...
Ngày tải lên: 13/08/2014, 23:20
bryce - pipe dreams; greed, ego and the death of enron (2003)
... Prohibition and the Ku Klux Klan In 1912, he and a prominent Houston oilman, Joseph Cullinan, formed the American Anti-Klan Association in an effort to force the KKK to disband It was a remarkable stand ... huge sums of money and did investment banking for the company, but their executives invested in Enron's off -the- balance-sheet partnerships And the same bankers employed a gaggle of analysts who, ... and Calhoun borrowed from a series of New York and Baltimore banks The two men used most of the money to acquire 800,000 acres of forestland, which Kirby and Calhoun believed might hold oil The...
Ngày tải lên: 01/11/2014, 19:11
the life and death of a pharaoh
... please the gods He made all the laws, and was also commander-inchief of the army Above all, the pharaoh had to maintain ma’at (harmony and order) and hold the regions of Upper and Lower Egypt together ... represented both the rebirth of the land through the Nile floods, and the rebirth of the body in the afterlife BOOK OF THE DEAD This Hall of Judgement picture comes from the tomb of Hunefer, a scribe ... linen, first the head, then each toe and finger, then the arms and legs, and finally the trunk were painstakingly wrapped The bandages were kept tight and coated with resin to stiffen them was covered...
Ngày tải lên: 14/11/2014, 08:59
Developing an integrated quantity and quality approach for improving the performance of multistage manufacturing systems
... results from the analytical model and simulation 51 3.6 The best sampling plans of cases and 54 3.7 The best sampling plans of Cases 19 and 20 56 4.1 Balance equation ... business environment, thereby pressurizing manufacturers to enhance manufacturing performance for financial survival (Anand and Kodali, 2009) In the past decades, manufacturers of many industries have ... critical to manufacturing industries, and losses of quality may significantly undermine profit and competitiveness of manufacturers (Colledani and Tolio, 2006) For instance, the number of automobile...
Ngày tải lên: 09/09/2015, 17:58
Social media and the perfect crime towards the death of reality, representation and the murder of resistance
... the theory of the steering of the possible planning and arrangement of human labour Cybernetics transforms language into an exchange of news The arts become regulated-regulating instruments of ... unified the field of control and communication theory, and defined it with the same title as his book: as the study of control and communication in the animal and the machine The study of messages, ... through these quantifiable objectives, that the goals of the organization can be fulfilled, for every employee understands the vision of these goals and objectives and thus the end goal of a smoothly...
Ngày tải lên: 30/09/2015, 10:12
Tài liệu Title: The Death of Lord Nelson ppt
... and ADAIR, Lieutenant ROTELY of the Marines, and some of the Midshipman on the Victory's poop, for some time afterwards At length one of them was killed by a musket-ball: and on the other's then ... suffer, and now and then a Commander be picked off: but it never can decide the fate of a general engagement; and a circumstance in many respects similar to that of the Victory's running on board of ... chosen for the reception of the Body; which, after the hair had been cut off, was stripped of the clothes except the shirt, and put into it, and the Cask was then filled with brandy.[23] In the evening...
Ngày tải lên: 21/02/2014, 20:20