the critical appraisal of structures
Báo cáo y học: "A critical appraisal of guidelines for the management of knee osteoarthritis using Appraisal of Guidelines Research and Evaluation criteria" doc
... clinicians There has, however, been increased scrutiny of the quality of guidelines in recent years This emphasis is in part related to the relatively recent work of the Appraisal of Guidelines ... related to the weaker evidence regarding the effectiveness of these interventions The role of these interventions should be specified in future guidelines AGREE evaluation of guidelines The AGREE ... and design of the study, in the acquisition and interpretation of data, and in the revision of the manuscript All authors read and approved the final manuscript SP additionally drafted the manuscript...
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báo cáo khoa học: "R-CHOP versus R-CVP in the treatment of follicular lymphoma: a meta-analysis and critical appraisal of current literature" ppt
... important to assess the relative efficacy of the two treatments Our first analysis reviewed the studies of frontline treatment of patients with FL using either R-CVP or R-CHOP There are no published ... of those met all inclusion criteria as studies of frontline or re-treatment Two of those four met the criteria for the first analysis (frontline treatment alone) Outcome The primary goal of the ... Combining the studies, there were 439 patients, and over 98% of these were late-stage Treatment efficacy The main characteristics of the four studies are shown in table 3, where it is seen that the...
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Báo cáo y học: "Systematic review: Intra-aortic balloon counterpulsation pump therapy: a critical appraisal of the evidence for patients with acute myocardial infarction" doc
... those in the Randomized IABP Trial Critical appraisal of randomized clinical trials of IABP therapy in AMI patients Thorough critical appraisal involves determining the validity of the study ... determining the validity of a therapeutic article, we ask whether the results represent an unbiased estimate of the treatment effect [13] First, we ask if the assignment of patients was randomized? In the ... single measure of its desirability from an efficiency perspective Critical appraisal of the economic analysis of IABP therapy in AMI patients The factors which we consider when critically appraising...
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Báo cáo y học: "Dialysis dose in acute kidney injury: no time for therapeutic nihilism – a critical appraisal of the Acute Renal Failure Trial Network study" ppt
... finding and the investigators should be congratulated for their efforts Nevertheless, because of the landmark nature of the trial, a critical analysis is certainly in order The purpose of the present ... comparison with the results of prior studies, and provide potential explanations for the different results Finally, we discuss the implications of the ATN results for clinical practice Design of the Acute ... supporting the overall high level of illness severity in the study is the high percentage (78%) of patients who were oliguric In accordance with the baseline cSOFA score, CRRT or SLED was the initial...
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The Critical Period of American History docx
... the highlands separating the Atlantic watershed from that of the St Lawrence, should follow these highlands to the head of the Connecticut River, and then descend the middle of the river to the ... the forty-fifth parallel, thence running westward and through the centre of the water communications of the Great Lakes to the Lake of the Woods, thence to the source of the Mississippi, which was ... intercourse;] The Americans retained the right of catching fish on the banks of Newfoundland and in the Gulf of St Lawrence, but lost the right of drying their fish on the Newfoundland coast On the other...
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The Gospels in the Second Century An Examination of the Critical Part of a Work Entitled ''''Supernatural Religion'''' pptx
... will then remain the specifying of Arabia as the home of the Magi, the phrase [Greek: kathezomenos] used of John on the banks of the Jordan, the two unparallelled sentences, and the cave of the ... be the adoration of the Magi, the slaughter of the innocents, the flight into Egypt, the conjunction of the foal with the ass in the entry into Jerusalem All these are strong evidence for the ... notices of the miracles in general, the healing of the lame and the paralytic, of the maimed and the dumb, and the raising of the dead not only did they include several discourses, such as the reply...
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Báo cáo khoa học: " Interactions between Scots pine, Ips acuminatus (Gyll.) and Ophiostoma brunneo-ciliatum (Math.): estimation of the critical thresholds of attack and inoculation densities and effects on hydraulic properties in the stem" pdf
... both in the phloem and the sapwood in response to bark inoculation They may therefore, together with the development of the fungus, have a negative impact on the water conducting ability of the sapwood, ... Impact of the density of inoculations with Ophiostoma brunneo-ciliatum into bark of young Scots pine trees on: (a) the length of the induced reaction zones in the bark tissues; (b) the fraction of ... potential The most striking result was the significant but nonlinear relationship between the amount of damage and the loss of conductivity; the latter increasing much faster then the former Loss of...
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Báo cáo toán học: "A Note on the Critical Group of a Line Graph" doc
... consequence of the matrix-tree theorem that the number of elements of the sandpile group with sink w∗ is equal to κ(G, w∗ ) For a basic exposition of the properties of the sandpile group, the reader ... Further, in the case in which the out-degree of each vertex of G is a fixed integer k, we show the kernel of this surjection is the k-torsion subgroup of K(LG, e∗ ) These results appear as Theorem ... = (w∗ , v∗ ), then κ(G, w∗ ) divides κ(LG, e∗ ) under the hypotheses of our Theorem This leads him to ask the natural question as to whether K(G, w∗ ) is a subgroup or quotient of K(LG, e∗ )...
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Báo cáo y học: "The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin" ppsx
... one of approximately 1.5 kb and the other of approximately kb The 1.5 kb fragment contained CDR2 and CDR3 of the IgG VL region and also part of the downstream expression vector containing the ... cDNA, while the kb fragment contained CDR1 and the rest of the vector The kb fragment derived from one VL expression vector was ligated with the 1.5 kb fragment derived from the other The resulting ... pairs from the beginning of VL, but does not cut the expression vector outside the insert Pvu I cuts the vectors at a single site approximately kb downstream of the insert Each vector was therefore...
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The economic appraisal of investment projects at EIB
... Bank The Economic Appraisal of Investment Projects at the EIB rate of return (FRR), i.e the discount rate that yields a zero net present value of the cash flow over the lifetime of the project The ... adequate indicator for the This introduction builds partly on the note to the Board of Directors of 2008 The Economic Appraisal of Projects: An Overview of the Approach within the Bank” 08/580 prepared ... associated to the intrinsic quality of the asset, the operation and maintenance policies, the use of the asset and the environmental conditions The PJ team will also assess the probability that the economic...
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Báo cáo y học: " Introducing the Critical Care Forum’s ongoing review of medical statistics"
... Critical Care February 2002 Vol No Whitley and Ball that cover the ideas presented in this series, and more, in considerably greater detail [1–4] However, even these might frequently ... these might frequently not be sufficient and it is vital that researchers recognise their own limitations and seek professional advice whenever it is needed, if only for reassurance Medical statistics ... role only after years of training and practical experience Most academic departments, and also many clinical departments, include properly qualified medical statisticians and they should be consulted...
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Tài liệu CCNA v2.0 Review Critical Concepts of the 640-802 CCNA Exam ppt
... receives BPDUs from the Root If multiple BPDUs are received, then there must be a loop in the network The BPDU with the lowest cost is the best path to the Root • The goal of every non-root bridge/switch ... protocol is the protocol being mapped across the frame relay cloud, such as IP or IPX • destination-IP is the IP address of the frame relay interface at the other end of the PVC • local-DLCI is the local ... called the “last mile” • Normally not more than a few miles Demarcation Point (Demarc) • The line between the customer site and the provider network • Inside of the demarc is the CPE • Outside of the...
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Tài liệu University Oars Being a Critical Enquiry Into the After Health of the Men Who Rowed in the Oxford and Cambridge Boat-Race, from the Year 1829 to 1869, Based on the Personal Experience of the Rowers Themselves pdf
... rows in the race ought to live till the age of 60; and if all the members of the Oxford 1829 crew had lived till the 10th of June, 1869, the 40th anniversary of the race, and then died, their lives ... Matches came off, in which 32 crews competed In the case of each of these crews I have calculated the probable duration of life of the different Oarsmen of whom they were composed: the following ... expectation of life of each one of them, according to Dr Farr's Tables, would then be 14 years, the value of the five lives together being 70 years On adding these 70 years of estimated life to the years...
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Tài liệu Báo cáo khoa học: Crystal structures of the regulatory subunit of Thr-sensitive aspartate kinase fromThermus thermophilus pdf
... of the structure are not seen on the map, probably owing to disorder of these regions The overall geometry of the model according to the procheck program [21] is of good quality, with 95.4% of ... to elucidate the mechanism of the elevated thermostability of TtAKb In this article, we describe the crystal structures of TtAKb in two forms, Thr-bound and Thr-free, and discuss the regulatory ... regulatory mechanism of Thr and the structural features responsible for the high thermostability of TtAKb Results and Discussion Model quality The crystal structure of the Thr-bound form of TtAKb ˚ (TtAKb-Thr)...
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Tài liệu Báo cáo khoa học: The most C-terminal tri-glycine segment within the polyglycine stretch of the pea Toc75 transit peptide plays a critical role for targeting the protein to the chloroplast outer envelope membrane ppt
... targeting of Toc75 remains unknown In this report, we extended the analysis of the polyglycine stretch of the Toc75 transit peptide in order to better understand the targeting mechanism of the chloroplast ... frequently in these regions Together they account for 17% of residues within this stretch We replaced the critical tri-glycine within the pea Toc75 transit peptide with repeats of these three FEBS ... considered the possibility that the difference between AAG and the other two mutants might be due to kinetics of the import; i.e., AAG precursor might be imported into the stroma more slowly than other...
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Tài liệu Báo cáo khoa học: Critical roles of Asp40 at the haem proximal side of haem-regulated phosphodiesterase from Escherichia coli in redox potential, auto-oxidation and catalytic control doc
... differences in the spectral maxima in the visible region of the Fe(III) species, spectra of the Asp40 mutants were essentially similar to that of the wild-type protein Additionally, spin states of the Fe(III), ... significantly affect the binding of exogenous ligands, such as the cyanide anion, to the Fe(III) complex [17], and O2 and CO to the Fe(II) complex [18] However, the PDE activities of these mutants are ... binding provide valuable information on the haem distal structure of Ec DOS PAS [17] As the structure of the cyanide-bound complex of FixL is similar to that of its oxygen-bound complex [10], a cyanide...
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Tài liệu Báo cáo khoa học: Models and mechanisms of O-O bond activation by cytochrome P450 A critical assessment of the potential role of multiple active intermediates in oxidative catalysis doc
... intermediate [11] The sum of these ndings points at the involvement of more than one active oxidant in the diverse types of P450-catalyzed substrate processing [1215] The goal of the present perspective ... which small alterations in the environment can cause drastic changes in the reactivity of the active species [76] Further support in favour of the idea of the involvement of a high-valent iron-oxene ... alignment of the CYP19 sequence with the known crystal structures of bacterial P450s, E302 was postulated to be essential to activation of the 19-oxo group of the substrate for attack by the peroxo-iron...
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Tài liệu Hiring and Performance Appraisal of the Executive Director ppt
... important It is the blending of the roles of the board and the executive director that moves the organization towards its missions and vision When the differences in the roles of the two are clearly ... of the reporting The committee coordinates the information from the external feedback sources Working with the executive director, the committee sets the schedule for the appraisal meeting, the ... on the working relationships between the executive director and the staff Step 4: Gather Documentation The information that the committee needs to gather for the performance appraisal of the...
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