... prevent the appearance of the released forms of MMP-9 from the complex The arrowhead shows the border between the stacking and separating gels, and the arrow shows the position of the 72 kDa form of ... the gelatinase, as well as the cABC degradation of the CS-chains of the PG The presence of 4.5 M urea in the proMMP-9/CSPG preparation had no effect on the position of the two main gelatinase bands ... shows the border between the stacking and the separating gel Due to the high glycosylation of the proMMP-9/CSPG complex, the proteins migrate as if they initially are distributed to the edges of the...
Ngày tải lên: 17/03/2014, 10:20
... well as of the full core oligosaccharide of P syringae pv phaseolicola GSPB 711 (Fig 5) The structure of the P syringae LPS core is similar but not identical to that of other members of the genus ... result of the anisotropy of the carboxyl carbon of KdoIII The data obtained suggested that OSNaOH-II has the structure shown in Fig The structures of the alkaline degradation products were further ... [25] The following correlations in the ROESY spectrum of OSNaOH-I were observed between the anomeric protons of the outer core monosaccharides and the protons at the linkage carbons of the neighboring...
Ngày tải lên: 23/03/2014, 13:20
The core competence of the corporation
... most of their cash under their mattresses The benefits of competencies, like the benefits of the money supply, depend on the velocity of their circulation as well as on the size of the stock the ... at the risks they are running Companies that judge competitiveness, their own and their competitors’, primarily in terms of the price/performance of end products are courting the erosion of core ... compressors But these are not just components They are core products that contribute to the competitiveness of a wide range of end products They are the physical embodiments of core competencies...
Ngày tải lên: 03/07/2015, 19:53
báo cáo khoa học: " Female heterozygotes for the hypomorphic R40H mutation can have ornithine transcarbamylase deficiency and present in early adolescence: a case report and review of the literature" docx
... previously obtained from the patients and/or their parents for the original publication of the case discussed in the literature review Acknowledgements The authors would like to thank the families included ... strongly suggest this conclusion Manifestations of OTCD are highly variable and depend upon the severity of the mutation and sex of the individual The classic presentation is males with hemizygous ... stress, the postpartum period [12], and certain drugs, notably sodium valproate [13] The diagnosis can be made on elevated serum ammonia with high urinary orotate The aim of treatment of episodes of...
Ngày tải lên: 11/08/2014, 02:22
Báo cáo y học: " Profiles of family-focused adverse experiences through childhood and early adolescence: The ROOTS project a community investigation of adolescent mental health" doc
... and 14% of the overall sample (c = 46.3, 6df, p
Ngày tải lên: 11/08/2014, 15:22
Báo cáo y học: " the Value of Serum Biomarkers (Bc1, Bc2, Bc3) in the Diagnosis of Early Breast Cancer"
... since none of them alone is useful for the majority of the BC and none of them is specific for cancer or breast tissues No biomarker has been suggested to date for the early diagnosis of BC (24) ... evaluate the actual performance of these markers Jinang Li, from the John Hopkins Hospital, is the first to explore proteomics in early diagnosis of BC, who also enabled the advance of proteomics ... Med Sci 2011, The results of the present study and the other three studies did not fully confirm each other Several hypotheses may be suggested to explain these differences First of all, Li’s...
Ngày tải lên: 25/10/2012, 11:15
Báo cáo y học: " Vacuum-assisted closure in the treatment of early hip joint infection"
... components of the immune system to the infected area is facilitated, which leads to a significant reduction of the bacterial count The efficacy of the V.A.C therapy has been 245 proven in the treatment ... reduction, the V.A.C.-system is not often used in the treatment of prosthesis – related infections Currently, there exist only four reports about the use of the V.A.C – system in the infection ... means of the V.A.C.-therapy at the site of an early hip joint infection We believe that the careful patients’ selection as well as the modified technique is responsible for the good outcome In the...
Ngày tải lên: 26/10/2012, 09:53
Báo cáo y học: "PKC and PKA Phosphorylation Affect the Subcellular Localization of Claudin-1 in Melanoma Cells"
... active PKC may exist in the nucleus of melanoma cells, and the presence of active PKC isoforms in the nuclei of many cell types has been confirmed (10-12) Staining of the G361 cells with antibodies ... signal (CLDN1-NLS), there is increased expression of claudin-1 in the nucleus, but there are still large amounts of claudin-1 in the cytoplasm as well B) All of the claudin-1 in the nucleus can be ... expressed in the nucleus, PKA causes its translocation to the cytoplasm It is unclear what the significance of claudin-1 in the nucleus may be It is known that the nuclear expression of other tight...
Ngày tải lên: 03/11/2012, 11:17
Tài liệu The New Generation of Microsoft Certifications: What’s at the Core? pdf
... Microsoft currently offers two Professional series credentials, the Microsoft Certified IT Professional (MCITP) and the Microsoft Certified Professional Developer (MCPD) Microsoft Certified IT Professional ... Microsoft Office Live Communications Server 2005 • Technology Specialist: Microsoft Windows Mobile 5.0 Applications The Professional Series (MCITP/MCPD) The Professional Series credentials are the ... certifications So, what are these all about and why is there a new generation of credentials? One of the problems today is that there are an abundance of credentials in the IT world, making it increasingly...
Ngày tải lên: 17/01/2014, 06:20
Tài liệu The New Generation of Microsoft Certifications: What’s at the Core? pptx
... Microsoft currently offers two Professional series credentials, the Microsoft Certified IT Professional (MCITP) and the Microsoft Certified Professional Developer (MCPD) Microsoft Certified IT Professional ... Microsoft Office Live Communications Server 2005 • Technology Specialist: Microsoft Windows Mobile 5.0 Applications The Professional Series (MCITP/MCPD) The Professional Series credentials are the ... certifications So, what are these all about and why is there a new generation of credentials? One of the problems today is that there are an abundance of credentials in the IT world, making it increasingly...
Ngày tải lên: 17/01/2014, 09:20
Tài liệu The Early Detection Research Network: Investing in Translational Research on Biomarkers of Early Cancer and Cancer Risk docx
... strongly to early detection of cancer coupled with appropriate therapy Yet, there are no validated molecular biomarker tests for the early detection of any cancer (see Table I) Among the list of Food ... to the effectiveness of early detection in reducing cancer mortality Since the introduction of Pap test screening, the incidence of cervical cancer in the United States decreased 70% While early ... and release mucus and other fluids) Definition of rectal cancer: Cancer that forms in the tissues of the rectum (the last several inches of the large intestine before the anus) Estimated new...
Ngày tải lên: 14/02/2014, 21:20
Tài liệu Báo cáo khoa học: Ionic strength and magnesium affect the specificity of Escherichia coli and human 8-oxoguanine-DNA glycosylases pdf
... sharply than on the 8-oxoG:C Whereas in the absence of KCl and MgCl2 in the reaction mixture, the activities on these substrates were at least of the same order of magnitude and the opposite-base ... [19,20] The results of the fluorescence titration experiments are summarized in Fig In the absence of MgCl2, the affinity of Fpg for the THF:C ligand was 1.6-fold higher than for the THF:A ligand The ... proteins may be affected by ionic strength, the concentration of divalent cations such as Mg2+, the nature of the buffering agents, the presence of competing polyamines and other small molecules,...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu The Economic Promise of Investing in High-Quality Preschool: Using Early Education to Improve Economic Growth and the Fiscal Sustainability of States and the Nation pptx
... rapid growth in the size of the labor force In the coming years, labor force growth will slow sharply as the baby boom generation retires Furthermore, improving the quality of the labor force ... status Well-off families know the value of high-quality preschool programs, and 70 percent of high-income families send their children to preschool (see Figure 2) At the other end of the income ... whatever quality of program they can afford and/or is offered in their neighborhood In 43 states, the average cost of full-day early education and care for four-yearolds exceeds the cost of attending...
Ngày tải lên: 20/02/2014, 20:20
Tài liệu The Basis of Early Christian Theism ppt
... because of their rejection of the gods of Greece and Rome; of immorality, because of the secrecy and mystery of their meetings, and cannibalism, because of their doctrine of the partaking of the ... hoi theoi, to theion} and {ta theia} They never conceive of their {theos} as anything more than a rather larger and more majestic member of the innumerable family of the divinities of which the ... existence of the former of these, it is true, as of the latter, may be obscured and nearly obliterated by sin and the consequent disorganization; for in the teaching of the Fathers, as in that of their...
Ngày tải lên: 21/02/2014, 08:20
Tài liệu The Conquest of the Old Southwest: The Romantic Story of the Early Pioneers into Virginia, The Carolinas, Tennessee, and Kentucky 1740-1790 pot
... fertility of the land, the healthy temperature of the air and the mildness of the climate, the plenty of hunting, fishing and fowling, the facility of trade with the Indians and the vast convenience of ... Fort in the midst of their towns at their own Request." The fort thereupon begun must have stood near the mouth of the South Fork of the Catawba River, as Dobbs says it was in the "midst" of their ... COLONIZATION OF THE CUMBERLAND XVIII KING'S MOUNTAIN XIX THE STATE OF FRANKLIN XX THE LURE OF SPAIN THE HAVEN OF STATEHOOD THE CONQUEST OF THE OLD SOUTHWEST Chapter I The Migration of the Peoples...
Ngày tải lên: 21/02/2014, 14:20
SURVEY OF GYNECOLOGICAL PROBLEMS DURING CHILDHOOD AND EARLY ADOLESCENCE IN A ACADEMICCENTER ppt
... changes further Lengthening of the corpus is followed by an increase in the width and thickness of both the corpus and cervix By the end of puberty the cervix-corpus ratio is 1:2 Gradually the endometrium ... tumors In the first two decades of life the incidence of epithelial tumors varies from 4% to 13% (Hunt et al 1979) The epithelial tumors presenting in the first two decades of life are usually of low ... salpingooophorectomy is the treatment of choice The course is benign in 70–95% of cases and the mortality rate low, 7% (Cronje et al 1999) The stage at the time of diagnosis and mitotic activity of the tumor...
Ngày tải lên: 05/03/2014, 13:20
Báo cáo khoa học: C fi G base mutations in the CArG box of c-fos serum response element alter its bending flexibility Consequences for core-SRF recognition potx
... single and double mutations affect binding of the proximal core- SRF subunit to the first half-site of the CArG box As a matter of fact, the structure of the (A ⁄ T) domain of the three oligonucleotides ... reveals that core- SRF modulates the inducible conformational properties of SRE [23,24] The origin of the adequate conformational deformation of the CArG boxes lies in the polymorphism of the (A ⁄ ... the role of the base sequence at the border of the A ⁄ T track in the specific complex assembly and functional organization How mutations affect binding of the core- SRF and generate a lack of defined...
Ngày tải lên: 07/03/2014, 09:20
Báo cáo khoa học: Local changes in the catalytic site of mammalian histidine decarboxylase can affect its global conformation and stability pptx
... radius of the protein, as the major diameter of the dimer is predicted to be given by the distance between the carboxy termini of both monomers (from the lower left to the upper right of Fig ... postulated the hypothesis that the observed high degree of rotation of the torsion angle v induced by the presence of the substrate could produce a remarkable conformational change in the whole ... is the final product of the reaction with HisOMe In fact, after min, the spectra of the HisOMe-treated samples had stabilized with the 390-nm peak as the major and final one In the reaction in the...
Ngày tải lên: 08/03/2014, 08:20
CORE PRINCIPLES OF MEDIA LITERACY EDUCATION in the UNITED STATES potx
... critically It expands the boundaries of the field to encompass not only what we teach but also how we teach, thereby distinguishing these as Core Principles of "media literacy education" rather than solely ... consistent with their own values 6.2 MLE helps students become aware of and reflect on the meaning that they make of media messages, including how the meaning they make relates to their own values ... of the Core Principles primarily addresses classroom teachers in the United States The “Implications for Practice” section is written with them in mind Our intention is that future versions of...
Ngày tải lên: 08/03/2014, 19:20