the cause of the war of spanish succession in 1701 was
The Female Brain is one of the most-talked-about books of the year. ppt
Ngày tải lên :
08/03/2014, 23:20
... obsessed about
scoring in games, and in the backseat of a car. At the point when
boys and girls begin deciding the trajectories of their careers, girls
start to lose interest in pursuits that ... response. The girls will think that if they do
it just right, they’ll get the reaction they expect. It’s the same kind of
instinct that keeps a grown woman going after a narcissistic or other
-
wise ... to the brain, and the brain does all the
interpreting. A good conk on the head in the right place can mean that
you won’t be able to smell or taste. But the brain does more than that.
It profoundly...
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Báo cáo khoa học: Interaction of the E2 and E3 components of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus ppt
Ngày tải lên :
16/03/2014, 18:20
... 119–171) of the B. stearothermophilus
E2p polypeptide chain with the dimer of a protein
domain (E3int) representing the interface domain (resi-
dues 343–470) of B. stearothermophilus E3. The use of
the ... domains, followed by a peri-
pheral subunit-binding domain (PSBD) responsible for
binding E3 in the majority of organisms. In icosahe-
dral complexes, the PSBD is also involved in the bind-
ing of ... close to the twofold axis of E3
preventing the association of a second PSBD [28,29].
The interaction occurs at the C
2
-axis of symmetry in
the E3 dimer, chiefly with the interface domain of E3,
which...
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Tài liệu THE HISTORY OF THE RISE, PROGRESS, AND ACCOMPLISHMENT OF THE ABOLITION OF THE SLAVE-TRADE pdf
Ngày tải lên :
15/02/2014, 09:20
... this uneasiness continued till he was assured that the
introduction of them in this capacity into his foreign dominions was the readiest way
of converting them to the principles of the Christian ... examining it in three points of view. First, as it has been proved to arise on
the Continent of Africa, in the course of reducing the inhabitants of it to slavery.
Secondly, in the course of ... presume the reader will
not be a little interested and entertained, in viewing with me the course of the abolition
of the Slave Trade, in first finding its source, and then in tracing the different...
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Tài liệu Đề tài " Asymptotic faithfulness of the quantum SU(n) representations of the mapping class groups " pdf
Ngày tải lên :
16/02/2014, 05:20
... consequence of Corollary 1.
In this paper we have initiated the program of using of the theory of
Toeplitz operators on the moduli spaces in the study of TQFT’s. The main
insight behind the program is the ... get that the norm of the Reshetikhin-Turaev quan-
tum invariant for all k and n =2(n = 3 in the genus 2 case) can separate the
mapping torus of the identity from the rest of the mapping tori ... invariants, resulting
in interesting topological conclusions, including very strong knot theoretical
corollaries. Writeup of these further developments is in progress.
It is also an interesting...
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Tài liệu Báo cáo khoa học: Characterization of the interaction between the plasma membrane H+-ATPase of Arabidopsis thaliana and a novel interactor (PPI1) doc
Ngày tải lên :
19/02/2014, 07:20
... or by
FC-induced binding of 14-3-3s.
Results
The C-terminus of isoform 1 of the PM H
+
-ATPase
of A. thaliana (AHA1) interacts with the first 88 amino
acids of PPI1 [22], indicating that the PM ... suggested by
the parallel increase of the number of FC-binding
sites [18–20]. As to auxin, a soluble auxin receptor has
been reported to bind and activate the PM H
+
-ATPase,
but the site of binding has ... fusion protein, containing
the PPI1 protein devoid only of the last 24 amino
acids, a putative transmembrane domain (PPI1
588
His
6
);
the His-tag was fused to the protein C-terminus, to
minimize...
- 8
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- 0
BURN THE FAT FEED THE MUSCLE Fat Burning Secrets of the World’s Best Bodybuilders & Fitness Models pdf
Ngày tải lên :
06/03/2014, 01:22
... powerful fat burning principles on Earth. The proof as
they say, is in the pudding!
Be patient in the beginning – all the information in the early chapters will come
together in the end
It ... mind has two components: The conscious and the subconscious. The
conscious mind is the rational, logical, analytical, thinking part of the mind. The
conscious mind is constantly taking in information ... visualization in many ways: they visualize
their workouts or they see themselves successfully completing a lift or performing aerobic
training. They also see pictures of their bodies the way they want them...
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Báo cáo khoa học: Structural mobility of the monomeric C-terminal domain of the HIV-1 capsid protein pptx
Ngày tải lên :
07/03/2014, 06:20
... peptides, other regions of
the Gag protein, or even other proteins). In the first
three examples, the second helix (as in CACW40A) was
the main element of secondary structure affected; in the
last ... deposited
structure: the first a-helix is in blue; the second one in green; and
the last a-helix is shown in yellow. The single turn of a 3
10
-helix at
the N-terminus of the protein is shown in red.
Dynamics of ... vectors
are independent of the overall rotational movement of
the molecule). Furthermore, the internal motions of
each bond vector are independent of each other, but the
rotational diffusion of the molecule...
- 13
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- 0
Báo cáo khóa học: Disruption of the interaction between the Rieske iron–sulfur protein and cytochrome b in the yeast bc1 complex owing to a human disease-associated mutation within cytochrome b potx
Ngày tải lên :
07/03/2014, 15:20
... discussed in greater detail below.
Instability of the mutant enzyme
Further analysis of the kinetic parameters of the G167E
mutant was hindered by rapid inhibition of the activity of
the bc
1
complex ... substrate
and the inherent partioning of quinol into the Q
o
site. The
Fig. 3. Steady-state level of the iron–sulfur protein (ISP) in G167E.
Immunoblots of denaturing gels, loaded with 40 lg of protein ... unstable
under the conditions of the assay. This was confirmed by
monitoring the sensitivity of the activity of the bc
1
complex
to detergent. The mutant enzyme was inactivated by a 2 min
incubation...
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- 0
Báo cáo khoa học: Solution structure of the active-centre mutant I14A of the histidinecontaining phosphocarrier protein from Staphylococcus carnosus ppt
Ngày tải lên :
07/03/2014, 16:20
... Ala19. In addition, the C-terminus
folds back onto the core of the protein thereby allowing the
side chain of Leu86 to partly fill the hole created by the
removal of Ile14. Due to these changes other ... into the active-centre loop. They lead to a dis-
placement of the ring system of His15 and a distortion of the
N-terminus of the first helix, which supports the histidine
ring. In ad dition, the ... The replacement of I le14 by Ala causes a slight
longitudinal compression of the mutant protein (Fig. 4). At
its N-terminal end, helix a displays a kink towards the
interior of the protein. The...
- 10
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- 0
Adventurers of the Far North A Chronicle of the Frozen Seas doc
Ngày tải lên :
08/03/2014, 15:20
... were
off again, the river winding and turning in its course but heading for the north-west. Here and there on the
banks they saw traces of the Eskimos, the marks of camp fires, and the remains of ... Franklin did the best he {98}
could; he read to them the creed of the Church of England in French. In the leisure part of the day a bundle of
London newspapers was perused again and again.
The winter ... made in the middle of the night, but at this season of the
year the whole {60} scene was brilliant with the light of the midnight sun. The Indians stole to within two
hundred yards of the place indicated...
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- 0
Báo cáo khoa học: b-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins pot
Ngày tải lên :
15/03/2014, 10:20
... [38,39], the
enzymes involved in APLP1 ectodomain cleavage are
less well defined [40,41]. Irrespective of the identity of
the enzymes involved, ectodomain shedding of APP,
APLP1 and APLP2 results in the ... produc-
tion of ICDs for all three proteins was not decreased by loss of BACE1
activity. These results indicate that BACE1 is involved in regulating ecto-
domain shedding, maturation and trafficking of the ... r.p.m. The resulting suspen-
sion was then centrifuged at 175 000 g and 4 °C for 30 min,
and the upper 75% of the supernatant was collected. Protein
content was assessed using a bicinchoninic acid...
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Báo cáo khoa học: Structure–function analysis of the filamentous actin binding domain of the neuronal scaffolding protein spinophilin pot
Ngày tải lên :
16/03/2014, 06:20
... studies of the
actin binding domain of spinophilin. We demonstrate that the spinophilin
actin binding domain is intrinsically unstructured, and that, with increasing
C-terminal length, the domain ... of the spinophilin constructs, as this has been
shown to shift the activity of other proteins between
F-actin bundling and crosslinking [39].
Spinophilin is a pointed-end capping protein
In the ... high
degree of disorder in the ABDs of spinophilin and
neurabin. On the basis of these analyses, spinophilin
and neurabin ABDs were predicted to be intrinsically
unstructured proteins (IUPs).
Spinophilin...
- 10
- 437
- 0
Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot
Ngày tải lên :
18/03/2014, 01:20
... result-
ing in a chimeric protein designated gp130c.Inorderto
investigate the role of the membrane-proximal domains of
gp130 in receptor activation, the FNIII-domain deletions
were introduced into the ... domain in the membrane-proximal part of gp130
leads to a shift of the receptor areas involved in ligand
binding closer to the membrane, resulting in the inability of
the receptor chains to form ... membrane-proximal
domains of gp130 is limited to ensure the correct spacing
between the CBM and the membrane, each of the domains
was replaced by the corresponding domain of the GCSFR.
The replacement...
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