the brain in its direction

MANAGING WITH THE BRAIN IN MIND doc

MANAGING WITH THE BRAIN IN MIND doc

... pain. Those people who felt the most rejected had the highest levels of activity in this region.” In other words, the feeling of being excluded provoked the same sort of reaction in the brain ... from the blood, they are diverted from other parts of the brain, including the working memory function, which processes new information and ideas. This impairs analytic thinking, creative insight, ... But in the brain, the ability to feel trust and empathy about others is shaped by whether they are perceived to be part of the same social group. This pattern is visible in many domains: in sports...

Ngày tải lên: 06/03/2014, 19:20

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The Bible in its Making The most Wonderful Book in the World docx

The Bible in its Making The most Wonderful Book in the World docx

... to them again, explaining that they must wait in patience, quietly doing their daily work, and earning their own bread, as he and his companions had done whilst living in Thessalonica. (2 Thessalonians iii. ... learn the Law and serve God in His Temple. Matthew, therefore, was very learned in the books of the Law, and in the writings of the old prophets. As you all know, the Lord Jesus chose Matthew ... 'writing in pictures.' This was a very special kind of writing in ancient Egypt, and generally kept for important occasions. The lines in the middle give the same words, but in the ordinary...

Ngày tải lên: 16/03/2014, 15:20

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Báo cáo y học: "ntravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head"

Báo cáo y học: "ntravenous transplantation of allogeneic bone marrow mesenchymal stem cells and its directional migration to the necrotic femoral head"

... distributed in the right hip joint. Subse- quently, MSCs migrated into almost all organs, and were uniformly distributed in the brain, lungs, heart, kidney, intestine, hip joints and other organs ... tissues including brain, lungs, heart, kidneys, intestine and bilateral hip joints of nude mice. In rabbits, at 6 w after intravenous transplantation, GFP labeled MSCs were noted in the lungs, ... present, there are a lot of labeling methods including GFP la- beling, Lacz labeling, BrdU labeling, Y chromosome labeling and DiI labeling. GFP protein is stable. GFP gene can be transfected into...

Ngày tải lên: 25/10/2012, 11:18

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Tài liệu Báo cáo khoa học: Characterization of human deoxyribonuclease I gene (DNASE1) promoters reveals the utilization of two transcription-starting exons and the involvement of Sp1 in its transcriptional regulation ppt

Tài liệu Báo cáo khoa học: Characterization of human deoxyribonuclease I gene (DNASE1) promoters reveals the utilization of two transcription-starting exons and the involvement of Sp1 in its transcriptional regulation ppt

... related proteins, as shown in Fig. 1B. To evaluate whether the Sp1-binding site in the DNASE1 distal promoter is crucial for expression, a mutated binding site was introduced into the )197H construct, resulting ... site, and the numbers in parentheses below the diagram show the position of the corresponding nucleotides relative to the transcription start site in exon 1. In the expression vector ex-pDN, the Kozak ... supershifted the DNA– protein complex in association with reduction in the amount of the complex (lane 9), suggesting that Sp1 binds to the putative site in the region from )90 to )51 relative to the...

Ngày tải lên: 19/02/2014, 06:20

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Tài liệu Báo cáo khoa học: A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action docx

Tài liệu Báo cáo khoa học: A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action docx

... thus blocking protein synthesis and leading cells to death. The current model proposed for the mechanism of antitumour action of BS-RNase is based on the ability of the protein to resist the neutralizing ... with the protein disulfides are located in the plasma membrane. Furthermore, they show that, as proposed in the hypothesis above, the RNase monomers are linked through disulfides to the cell membrane, ... hypothesize that the cytotoxic activity of the latter monomers was due to the presence in these proteins of disulfide bonds, with their potential chemical instability. It is well known that in the...

Ngày tải lên: 20/02/2014, 11:20

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Tài liệu Báo cáo khoa học: Key role of the loop connecting the two beta strands of mussel defensin in its antimicrobial activity docx

Tài liệu Báo cáo khoa học: Key role of the loop connecting the two beta strands of mussel defensin in its antimicrobial activity docx

... molecule comprising Ôresidues in the protruding domain consisting of the type VI b-turn and the first part of b-strand 3Õ (i.e. the b-hairpin loop and part of the adjoining b-sheet) and Ôresidues in the loop ... in two discrete domains, led to the hypothesis that the positive cluster could initially dock the molecule onto the phospholipids and that the surrounding hydrophobic cluster could initiate the ... using the CLUSTAL X (1.8) algorithm on the PFAM arth- ropod defensin family. The boxed parts indicate the sequences com- prised between the half-cystines forming the b-strand loop of defensins. Characters...

Ngày tải lên: 20/02/2014, 11:20

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THE BUSINESS CAREER IN ITS PUBLIC RELATIONS potx

THE BUSINESS CAREER IN ITS PUBLIC RELATIONS potx

... Nearly all the individual works in the collection are in the public domain in the United States. If an individual work is in the public domain in the United States and you are located in the United ... going into business, let it be borne in mind that there are scientific principles underlying every branch of law, medicine, and the ministry in the list of the professions; that is to say, in ... are finding out and admitting the demand that present-day conditions impose, and are training many men in the pursuit of modern science, while they are training many others in the understanding...

Ngày tải lên: 05/03/2014, 16:20

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Báo cáo khoa học: Binding of cGMP to the transducin-activated cGMP phosphodiesterase, PDE6, initiates a large conformational change involved in its deactivation ppt

Báo cáo khoa học: Binding of cGMP to the transducin-activated cGMP phosphodiesterase, PDE6, initiates a large conformational change involved in its deactivation ppt

... [ 3 H]cGMP binding with a K d  50 nM and Pc inhibits the [ 3 H]cGMP binding. Binding of cGMP to Pabc is suppressed during its formation, implying that cGMP binding is not involved in Pabcc activation. ... mutant in which 18 amino acids in the N-terminus were deleted), N22del (a Pc mutant in which 22 amino acids in the N-terminus were deleted), C18Sub (a Pc mutant in which 18 amino acids in the C-terminus ... homogenates are incubated with GTPcS, the Pab content in membranes is increased 20–30% by binding of the Pab ⁄ Pc com- plex existing in the soluble fraction [13]. Therefore, binding of the Pab ⁄ Pc...

Ngày tải lên: 06/03/2014, 00:21

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Dynamic Planet Mercury in the Context of Its Environment docx

Dynamic Planet Mercury in the Context of Its Environment docx

... determining the moments of inertia of the principal axes. If a liquid layer, such as an outer core, decouples the inner core from the crust, then the moment of inertia of the crust may be determined ... and Figure 2-2. Mariner 10 spacecraft, illustrating the spacecraft design described in the text: The instrument package, including cameras boom mounted instruments, including the magnetometer, ... sensors were mounted on the tips of the solar panels. Simple thermal protection strategies involved: insulating the interior of the spacecraft, top and bottom, using multi-layer thermal blankets and...

Ngày tải lên: 06/03/2014, 19:20

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The Green House - New Directions in Sustainable Architecture pdf

The Green House - New Directions in Sustainable Architecture pdf

... 4 9 !NEXCEPTIONTOTHATRULEIS"ATTERY0ARK#ITY O NEOF.EW9ORKSMOSTPRO G RESSIVEURBANPLANNIN G VENTURESINT H EPASTT H REE D ECA D ES"UI L TONACRES OF LAND ẵ LLCREATEDBYEXCAVATINGTHE7ORLD4RADE # ENTERSITEINTHESTHEMIXEDUSEDEVELO P MENT H U GG IN G THESOUTHWESTERNED G EOF-ANHATTAN H ASFUNCTIONEDASALABORATOR Y FORANEWAPPROACH T OUR B AN L IVINGONET H ATCOM B INESPROXIMITYTO C UL T U REAN D COMMERCEWIT H AMENITIESAVAI L A BL E T O F EW.EW9ORKER S HARBORVIEWSAMARINAAND ẵ NEL Y LANDSCAPEDPARKSEMBELLISHEDWITHPUBLIC A RT/NEOFITSBOLDESTEXPERIMENTSWASESTABLISHING INASETO F ENVIRONMENTALGUIDELINESREQUIRING A LLNEWHOUSIN G TOBEAPPRECIABLYAHEADO F CURRENTSTANDARDSAND P RACTICESFORDEVELO P MENT 4HE3OLAIREASTORYAPARTMENTBUILDIN G AT T HESOUTHERNTIPO F THEDEVELOPMENTISTHE ẵ RST RESI D ENTIA L TOWERIN.EW9OR K TOSYSTEMATICA LL Y EMBRACESUSTAINABLEDESI G NANDTHE ẵ RSTTO COMPREHENSIVELYSATISFY"ATTERY0ARK#ITYS G REEN GUI D E L INES )THINKOFTHE3OLAIREASAGREATBIGGUINEAPIG ENTHUSESPROJECTARCHITECT2A F AEL0ELLIAPRINCIPALAT # ESAR0ELLI!SSOCIATES)TWILLEDUCATEANINDUSTRY A CROSSABI G SECTORANDEDUCATIONISAHU G EPART OF BRINGINGSUSTAINABLEBUILDINGPRACTICESINTOTHE MAINSTREAM 0 ELLIWHO G REWUPWATCHIN G HISFATHERARCHITECT # ESAR0ELLIDESI G NTHEMASTERPLANANDSEVERAL BUILDINGSFOR"ATTERY0ARK#ITYANDHISMOTHER L AN D SCAPEARC H ITECT$IANA"A L MORICREATEPAR K S ANDURBAN G ARDENSDEVELOPEDANEARLYINTERESTIN S USTAINABLEDESI G N!FTERJOININ G HISFATHERS.EW (AVEN#ONNECTICUTBASED P RACTICEINHE OPENEDTHEẵRM S.EW9ORK#IT Y OFẵCEIN4HE 3OLAIRECOMMISSIONALSOCAMEIN F OLLOWINGTHE ANNOUNCEMENTOFTHENEW G UIDELINES &ROMTHESTARTONEOFTHEBI GG ESTCHALLEN G ES FOR0ELLIANDHISTEAMWASTRANSLATINGWHATTHEY KNEWASGENERALPRINCIPLESO F SUSTAINABLEBUILDING M ETHODSINTOSPECIẵCDESI G NDECISIONS4HEREISA HU G E G APBETWEENTHETECHNOLO G YTHATEXISTSAND W HATISACTUALL Y AVAILABLEFROMMANUFACTURERS S A Y S0E LL I&OREXAMP L ET H EP H OTOVO L TAICCE LL ST H AT ẵ TTHEBUDGETCAMEONLYINBLUENOTTHEORIGINALLY S PECI ẵ EDCHARCOALCOLOR5LTIMATELY0ELLIEMBRACED THEBLUETILESTHEIRLIVELYLI G HTREắECTIN G SURFACES C REATEASTIPP L E D QUA L IT Y T H ATWOR K SWE LL WIT H T H E BUILDING STAUTSKINFACADE/THERDECISIONSWERE D ICTATEDBYTHETEAMSSELFIMPOSEDCOMMITMENT TOWORKIN G WITHLOCALMANUFACTURERS HALFOFALL M ATERIALSUSEDINTHECONSTRUCTIONWERE P ROCURED LOCALL Y ANDANOTHER ẵF THHADTOBEMANU F ACTURED W IT H IN MI L ES 0ELLISTEAMWENTTO G REATLEN G THSTOMAKE THERI G HTENVIRONMENTALCHOICESATEVERYSTA G E -ATERIA L SAN D SYSTEMSWERETESTE D AN D D ESIGNS R EVISEDACCORDINGLY!PLAN F ORBAMBOO ắ OORING W ASSCRAPPEDWHENTHEADHESIVEBACKIN G WAS D ETERMINEDTOBETOXIC.EWINSULATIONWASADDED A FT E R A N E L A B O R A T E W A LLM ODEL BUILTFULLSCALE ANDTESTEDINAWINDTUNNELATTHEDEVELOPER S E XPE N S E INDICATEDTHATONEEXTRALAYERO F SEALANT C OULDMAKEAHU G EDI FF ERENCEINTERMSO F LIMITIN G AIRINẵLTRATION )TTURNEDOUTTOBEASIM P LE S O LU TIO N ONEGUYWIT H AGOOPGUNGOESINAN D THEWHOLETHINGISTAKENCAREOF0ELLISAYS"UT W ITHOUTTHOSESTUDIESWEWOULDNEVERHAVEKNOWN I TWASNECESSARY )NCORPORATIN G ALON G LISTOFSUSTAINABLE TEC H NO L OGIEST H E3O L AIRESURPASSESA LL CURRENT E NVIRONMENTALGUIDELINESINE FF ECTIN.EW9ORK)T I SPERCENTMOREEFẵCIENTTHANTHE3TATE%NER G Y #ODEREQUIRES4HETOWER G ENERATESPERCENTO F I TSENERGYWITHTHEHELPOFSQUAREFEETO F 7HILETHE-ANHATTANSKYLINEIS F ULLO F INSTANTLYRECO G NIZABLE ICONSTHEDAYSWHENTHE"I G !PPLESTOODATTHE F ORWARDED G E O F ARCHITECTUREARELAR G ELYINTHEPAST4HETALLESTSKYSCRAPERS ARENOWRISIN G IN! SIAANDTHELATESTTECHNICALEN G INEERIN G INNOVATIONSAREMORELIKEL Y TOBEREALIZEDIN%UROPE5NTIL THEREDEVELOPMENTAT'ROUND:EROPROMPTEDARECENTSUR G E O F PUBLICINTERESTINARCHITECTUREANDURBANDESI G NBOTTOM LINEPRESSURESANDPRESERVATIONSTRU GG LESTENDEDTODOMINATE DISCUSSIONSABOUTARCHITECTUREIN.EW9ORK#IT Y :< & ACIN G WESTACROSST H E ( U D SON2IVERATT H ESOUT H ERNTI P OF -ANHATTAN THE3 OLAIREHAS EM B E DD E D PH OTOVO L TAIC P ANE L S TH ATCAPTURESUN L IG H TT H ROUG H OUT T HEDAYANDEVENATDUSKABOVE A SITBOUNCESOFFTHEWATER LO CATI O N N ew ... Design #ANADATHE5NITED3TATES*APANAND!USTRALIA RESIDENTIALARCHITECTSARECOMBININGEYECATCHING CONTEMPORARYARCHITECTUREWITHSUSTAINABILITY&ORA BOOKTHATWEBELIEVEISTHEẵRSTOFITSKINDWESETOUT TOSELECTTHEẵNESTEXAMPLESOFTHISNEWCONắUENCE ANDEXPLAINHOWEACHOFTHEMCAMEINTOBEINGWHO COMMISSIONEDTHESEHOUSESANDAPARTMENTBLOCKS HOWTHEIRDESIGNSEVOLVEDANDHOWTHEIRARCHITECTS ANDBUILDERSMANAGEDTOBALANCEENVIRONMENTAL ANDAESTHETICCONCERNSSOEFFECTIVELY 4HEMOREWEBEGANTOSEARCHFORSUCHPROJECTS THEMOREWEREALIZEDNOTJUSTHOWMANYAREOUT THEREINDEEDWEENDEDUPWITHMOREQUALIẵED PROJECTSTHANWEHADPAGESTOSHOWTHEMONBUT THEREMARKABLEREGIONALANDARCHITECTURALVARIETY THEYREPRESENT'REENHOUSESNOWRISEFROMTIGHTLY PACKEDCITYSTREETSASWELLASFROMLUSHHILLSIDESAND ROCKYSEASHORES4HEYARESINGLEFAMILYDWELLINGS ANDSUBSIDIZEDAPARTMENTSPRIMARYRESIDENCES ANDWEEKENDGETAWAYS4HEYARESHEATHEDIN GLASSINBAMBOOINSYNTHETICPANELSMADEFROM RECYCLEDNEWSPAPER4HEYTAKETHEIRAESTHETICCUES FROMPRIMITIVEDWELLINGSFROMORGANICFORMS ANDSIGNIẵCANTLYFROMARCHITECTURALPREDECESSORS WHOINCLUDETHEFOUNDERSOFTHE"AUHAUSASSURELY AS0AOLO3OLERIOR&RANK,LOYD7RIGHT)NFACTITIS BECOMINGIMPOSSIBLETOIGNOREHOWMANYGREEN HOUSESARENOWBEINGDESIGNEDINTHESLEEK ORNAMENTFREESTYLETHATHASONCEAGAINBECOMETHE PREVAILINGARCHITECTURALAPPROACHAMONGHIGHEND ARCHITECTSPARTICULARLYYOUNGERONESIN!MERICA AND%UROPE&ORTHEẵRSTTIMEINTHEHISTORYOFTHE GREENDESIGNMOVEMENTSUSTAINABILITYISBEING EMBRACEDBYTHEVERYSAMEARCHITECTSWHOSETTHE ẵELDSSTYLISTICANDTHEORETICALAGENDAS )NADDITIONTO$IETRICH3CHWARZSCORNEROF 3WITZERLANDOURSEARCHFORTHEHOUSESTHATẵLLTHE FOLLOWINGPAGESTOOKUSTOLOCATIONSALLAROUND THEWORLD/NTHEEDGEOF,AKE7ASHINGTONNEAR 3EATTLEWEDISCOVEREDANEWHOUSEBYTHEWELL KNOWN0ACIẵC.ORTHWESTẵRM/LSON3UNDBERG +UNDIG!LLEN)TSDESIGNISANCHOREDBYACURVING USHAPEDWALLTHATISANENGAGINGSCULPTURAL ELEMENTANDBECAUSEITBOTHCONDUCTSCOOLAIR INTHESUMMERANDBOUNCESSUNLIGHTBACKINTO THEINTERIORINWINTERTHEKEYTOITSREMARKABLE ENERGYEFẵCIENCY$OWNTHECOASTIN-ARIN#OUNTY #ALIFORNIAWEMET-ICHELLE+AUFMANNWHOHAD RECENTLYLEFTAJOBIN&RANK'EHRYSOFẵCETOSTART HEROWNẵRM+AUFMANNHASDESIGNEDTHEMODULAR 'LIDE(OUSETHEẵRSTMASSPRODUCEDGREENHOME )TCANBECUSTOMORDEREDANDTHENTRUCKEDDIRECTLY TOABUILDINGSITETOBECONSTRUCTEDINAMATTEROF WEEKSITISALREADYONTHEMARKETFORROUGHLY PERSQUAREFOOTABARGAINGIVENTHEHIGHQUALITY OFITSMATERIALSANDDESIGN !LITTLEFURTHERSOUTHWEWENTTOSEE#OLORADO #OURTAFORTYFOURUNITLOWINCOMEAPARTMENT COMPLEXIN3ANTA-ONICADESIGNEDBYTHEWELL REGARDEDẵRM0UGH3CARPA/NTHEOPPOSITE COASTWEFOLLOWEDTHEPROGRESSOF2AFAEL0ELLIS GREENAPARTMENTTOWERIN-ANHATTAN4HE3OLAIRE ISTHEẵRSTSUSTAINABLERESIDENTIALPROJECTOFITS SIZEORAMBITIONINAN!MERICANCITY!NDACOUPLE HOURSNORTHOF.EW9ORK#ITYWEDISCOVEREDTHAT 3TEVEN(OLLAMUCHLAUDEDARCHITECTWHOSENAME HASRARELYIFEVERBEENMENTIONEDINCONNECTION WITHGREENDESIGNHADDESIGNEDANADDITIONTO HISOWNWEEKENDHOMETHATINCLUDESALONGLIST OFSUSTAINABLEELEMENTSFROMSOLARPANELSTOAN INVENTIVENATURALVENTILATIONSYSTEM )N%UROPEWEFOUNDSUSTAINABLEDWELLINGS WITHALEVELOFARCHITECTURALANDENVIRONMENTAL SOPHISTICATIONTHATPUTSMOSTGREENBUILDINGSIN THE5 NITED3TATESTOSHAME)TISWELLKNOWNTHAT MANY%UROPEANCOUNTRIESHAVEBUILDINGCODES THATPAYSIGNIẵCANTLYMOREATTENTIONTOISSUES OFSUSTAINABILITYTHANTHOSEINTHE5NITED3TATES ,ESSREMARKEDUPONATLEASTINTHE!MERICAN PRESSHASBEEN%UROPESSUBSTANTIALINVESTMENTIN NEWHOUSINGTHATMEETSSTRINGENTSUSTAINABILITY BENCHMARKS#ITIESLIKE(ELSINKIAND3TOCKHOLM HAVEDEDICATEDHUGEANDVALUABLESWATHSOFLANDTO GREENDEVELOPMENTSSOMEOFWHICHCONTAINSEVERAL THOUSANDUNITSOFHOUSING .OTALLTHE%UROPEANPROJECTSTHATẵLLTHESE PAGESAREPUBLICLYSUBSIDIZEDTOBESURE/NA STEEPHILLSIDEOVERLOOKING3TUTTGARTWETOUREDTHE JAWDROPPING2ASTEELANDGLASSBOXDESIGNED BYTHE'ERMANENGINEER7ERNER3OBEKASHIS FAMILYRESIDENCE3INCETHEDAYSOF-IESVANDER 2OHES&ARNSWORTH(OUSEIN0LANO)LLINOISANDITS SEETHROUGHSIBLINGIN.EW#ANAAN#ONNECTICUT BY0HILIP*OHNSONBOTHẵNISHEDAROUND THEGLASSHOUSEHASSTOODASTHEEPITOMEOFTHE MODERNISTAESTHETICUNFORTUNATELYSUCHDWELLINGS HAVEOFTENBEENBOTHUNCOMFORTABLETOLIVEINTOO HOTINSUMMERTOOCOLDINWINTERANDWITHTHEIR HIGHHEATINGANDCOOLINGBILLSANDINSENSITIVITYTO SITEHARDLYKINDTOTHEENVIRONMENTEITHER3OBEK SETHIMSELFTHESTIFFCHALLENGEOFSTARTINGWITH THEFAMOUSTYPOLOGYOFTHEGLASSHOUSEANDTHEN MAKINGITSUPREMELYENERGYEFẵCIENT(ISDESIGN HASCERTAINLYBEENASUCCESSINTHATREGARDDURING 2BY7ERNER3OBEK ... EXPOSEDSTEELBEAMSCORRU G ATED M ETALDECKIN G ATTHECEILIN G SANDSMOOTHCONCRETE ắOORSTHATDOWNPLAYTHEBUILDING SENVIRONMENTAL AGENDA7HENTHEIRWALLSIZEALUMINUM F RAMED G LASS G ARA G EDOORSAREROLLEDUPTHELO F TSTYLE I NTERIORSTAKEONTHEFEELOFACOVEREDTERRACE 3MALLBALCONIESANDALAR G EROOFTOP G ARDENPROVIDE A DD ITIONA L O U T D OORACCESS 4 HE%AST5NION3TREETPROJECTISPARTO F A G ROWIN G TRENDTHATISLURIN G SUBURBANITESBACKTO THECITY4HEBUILDIN G ALSOREPRESENTSANEFFORTON THEPARTOFTHEDEVELOPERTOBRINGSOMEOFTHEBEST %UROPEAN D ESIGNI D EASTOT H E5NITE D 3TATES&OR E XAM P LESINCETHES Q UARE F OOT P ARCELWAS TOOSMALLTOACCOMMODATETHEEI G HTPARKIN G SPACES R EQUIREDBYTHENUMBEROFHOUSIN G UNITSINTHE B UI LD INGT H EARC H ITECTSINSTA LL E D H Y D RAU L ICPAR K ING LI F TSTHATALLOWTWOMEDI U MSIZECARS TH ESPACE I SINTENTIONALLYTOOSMALL F OR356S TOBESTACKED VERTICALLYINASIN G LESPACE%QUALLYIN G ENIOUSIS THEUSEOFTHEROOFASOUTDOORSPACE#ONẵGURED ASASERIESO F DECKSANDACCESSEDB Y METALSPIRAL S TAIRCASESTHEROO F O FF ERS P ANORAMICVIEWSO F 0U G ET3OUNDANDTHE/LYMPIC-OUNTAINS : 4 HEẵVESTORYMIXEDUSELOFT B UILDIN G IN3 EATTLE S0IKE0INE A REAHASALIMITE D N U MBERO F P AR K INGSPACESAN D ISWIT H IN WALKINGDISTANCEO F ALIGHTRAIL STATION 7HEN F ORMERHI G HTECHEXECUTIVE,IZ$UNNDECIDEDTOSTART ANEWCAREERSHEREVISITEDHEROLDDREAMO F BECOMIN G AN ARCHITECT! F TERTAKIN G A F EWCLASSESINARCHITECTUREURBAN PLANNIN G ANDREALESTATEDEVELOPMENTATTHE5NIVERSITY O F 7ASHIN G TONSHEEMBARKEDONANAMBITIOUSPROJEC T AREALESTATEVENTURETHATWOULDBLENDHI G HARCHITECTURAL ASPIRATIONSWITHENVIRONMENTALRESPONSIBILIT Y !LREAD Y ACOMMITTEDENVIRONMENTALACTIVISTSHEWASPARTICULARL Y CONCERNEDABOUTTHECULTURALCAUSESO F ENVIRONMENTAL DE G RADATIONESPECIALLYTHETENDENCY F ORSUCCESS F UL EXECUTIVESLIKEHERSEL F F OREXAM P LETOCOMMUTETOWORK DAIL Y F ROM$ISNE Y ESQUE-C-ANSIONSOUTSIDE3EATTLE LO CATI O N Seattle,...

Ngày tải lên: 14/03/2014, 17:20

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Báo cáo khoa học: The properties of phosphodiesterase 11A4 GAF domains are regulated by modifications in its N-terminal domain pptx

Báo cáo khoa học: The properties of phosphodiesterase 11A4 GAF domains are regulated by modifications in its N-terminal domain pptx

... small-molecule- binding domains that have been identified in > 3000 proteins throughout all taxonomic kingdoms [5,6]. The acronym GAF is derived from the proteins in which these domains were initially ... regulating the cGMP affinity of the PDE11A4 tandem GAF domain and thus allosterically affect PDE11 activity. The role of the N-terminus of the PDE11A4 GAF tandem domain The N-termini that precede the ... N-ter- mini of GAF-domain-containing PDEs that might contribute to intramolecular signalling in a similar manner. Another point merits discussion. Irrespective of phosphomimetic mutations or N-terminal...

Ngày tải lên: 16/03/2014, 06:20

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Báo cáo khoa học: Intermonomer cross-linking of F-actin alters the dynamics of its interaction with H-meromyosin in the weak-binding state ppt

Báo cáo khoa học: Intermonomer cross-linking of F-actin alters the dynamics of its interaction with H-meromyosin in the weak-binding state ppt

... produce an increase in rotational motion in the environment of the Cys374 site of actin [8]. In a recent publication the authors argue that in the weak binding state of myosin to actin the heads interact ... myosin and actin combine in a tight-binding state [24–26]. The transition from the intermediate weak-binding state to the strong-binding state requires a conformational change, an intramolecular motion ... restriction of the flexibility in cross- linked filaments. In the copolymers, subdomain 1, where the spin probe is attached, is not directly involved in the intermonomer cross-link, because one of the cross-linking...

Ngày tải lên: 16/03/2014, 13:20

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EVERYTHING IN ITS RIGHT PLACE: FOUCAULT AND THE ''''IDEOLOGY OF THE AESTHETIC'''' pptx

EVERYTHING IN ITS RIGHT PLACE: FOUCAULT AND THE ''''IDEOLOGY OF THE AESTHETIC'''' pptx

... eminently clear by the intertwining of these themes in the writing collected in the Essential Works. 32 Osborne's analysis of the conditions under which art criticism might be reimagined ... of the present establishes both the inadequacy of the 'art as aesthetics' thesis, and the ineliminability of the aesthetic dimension of artworks. Eagleton's The Ideology of the ... articulating aesthetic 29 Ibid., 311. 30 Ibid., 312. 31 Ibid., 315. 32 The interrelation of these domains is evident not least in the blurring of lines across the three volumes of the Essential...

Ngày tải lên: 16/03/2014, 18:20

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Báo cáo khoa học: Amino acid residues on the surface of soybean 4-kDa peptide involved in the interaction with its binding protein potx

Báo cáo khoa học: Amino acid residues on the surface of soybean 4-kDa peptide involved in the interaction with its binding protein potx

... & Tager, H.S. (1987) Role of the COOH- terminal B-chain domain in insulin–receptor interactions: identification of perturbations involving the insulin mainchain. J. Biol. Chem. 262, 12054–12058. 20. ... to the solvent. This suggests that the aromatic residue, Phe28, plays a vital role in maintaining the hairpin-b during interaction with solvent. Interaction of insulin with the 43-kDa protein Similarly ... of insulin–insulin receptor interaction, the area consisting of Ile25, Val29, Phe31 and Ile33 in the 4-kDa peptide should play a critical role in the interaction with the 43-kDa protein. These...

Ngày tải lên: 17/03/2014, 03:20

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The Fungal Community Its Organization and Role in the Ecosystem Third Edition docx

The Fungal Community Its Organization and Role in the Ecosystem Third Edition docx

... can then be tied to process level mechanisms. In addition to determining the interface between resources and organisms, it is also essential to determine the location of the substrate and the ... function in soil systems. Measurements of hyphal lengths can indicate the presence of a fungus at some time in the past, or they can indicate the presence of an active fungus, depending on the techniques ... dynamics are not important to the organization and structure of terrestrial systems. Exploring the interactions of fungi within the fungal community and their role in determining plant communities, especially...

Ngày tải lên: 23/03/2014, 01:20

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