... degrada- tion in the population of hemoglobin-positive cells. To the best of our knowledge, there has been no report on the promoter function of the human HO-2 Fig. 7. Characterization of the human ... degradation of the HO-2 mRNA. Functional analysis of the HO-1 and HO-2 gene promoters under hypoxia To address the question of whether hypoxia influences the promoter activity of the human HO-1 ... Taken together, these results indicate that hypoxia reduces the expression levels of HO-2 mRNA and protein in five out of six cell lines, with the exception of KG1 myeloid cells. Hypoxia decreases the...
Ngày tải lên: 19/02/2014, 06:20
... for the majority of cells to contain sub2N DNA. Furthermore, the Ymin (minimum response of the dose response curve) and the T = 0 values (the number of cells at Time zero) were determined from the ... be Figure 3 The response profile of GSK1070916 for cell lines with a primary diploid chromosome number (<50).Thepercentageof polyploidy within subpopulations of these cells is provided on the y ... to the sensitivity observed in these cell lines. Comparison of the two response phenotypes for modal chromosome number, using a chromosome count of (3n) as the cutoff, showed a difference in the response...
Ngày tải lên: 18/06/2014, 22:20
o cáo hóa học:" High Chromosome Number in hematological cancer cell lines is a Negative Predictor of Response to the inhibition of Aurora B and C by GSK1070916" ppt
... for the majority of cells to contain sub2N DNA. Furthermore, the Ymin (minimum response of the dose response curve) and the T = 0 values (the number of cells at Time zero) were determined from the ... to the sensitivity observed in these cell lines. Comparison of the two response phenotypes for modal chromosome number, using a chromosome count of (3n) as the cutoff, showed a difference in the response ... GSK1070916. Ymin values represent the bottom of theresponsecurveanddefinethelargesteffectofthe compound. These Ymin values are evaluated relative to the number of cells at time zero using a Ymin/T0...
Ngày tải lên: 20/06/2014, 04:20
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