... filtered into the interior, and so reached the pipes of the Chinese. Just why the Chinese chose to obtain their supplies from India is no clearer than why, having obtained it, they smoked instead ... by simply eating or drinking the drug. Thereafter wherever the Chinese went, to railroad construction sites in Nevada and canal digging in Panama, they carried the technique with them. To smoke ... Peace, and other nostrums containing the drug. But working mothers paid no attention to such warnings. They had to leave their infants in the care of old women or very young children when they went...
Ngày tải lên: 11/06/2014, 14:18
Ngày tải lên: 05/09/2013, 09:08
Tài liệu Central bank rates, market rates and retail bank rates in the euro area in the context of the recent crisis docx
... Conversely, in the case of the model estimated using the OIS, both the increase and decrease in the retail interest rate are principally due to the shock to the retail rate, which indicates ... is insuf- ficient for explaining the events during the crisis. The savings deposit interest rate is particularly important in Belgium, because it includes the interest rate applied to savings ... overnight interbank lending in the euro area. Under normal circumstances, this is the rate that the ECB seeks to in uence. In the years preceding the crisis, the market interest rates likely to be the...
Ngày tải lên: 15/02/2014, 05:20
Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx
... provided further insight into the molecular mechanism driving the formation of the covalent C115–fosfomycin adduct. A conservative exchange of K22 to arginine maintains fosfo- mycin binding, while ... lysine reduces the probability of forming the fully closed form of the protein. The results obtained with the K22V/R120K double mutant protein point toward a central role of arginine 120 in the ... uncharged valine side chain completely abolishes fosfomycin binding in the absence of UDPNAG. Clearly, UDPNAG binding creates additional favorable interactions that promote fosfomycin binding to the enzyme....
Ngày tải lên: 19/02/2014, 13:20
Tài liệu The Buccaneers in the West Indies in the XVII Century pdf
... pounds sterling.[21] In view of the prevailing east wind in these regions, and the maze of reefs, cays and shoals extending far out to sea from the Mosquito Coast, the galleons, in making their course ... workmen, the increase of imposts, and the prejudice against the mechanic arts, industry was being ruined; while the increased depopulation of the realm, the mainmort of ecclesiastical lands, the majorats ... between the Virginian Capes and the Bermudas to about 38°, in order to recover the strong northerly winds, and then east to the Azores. In winter the galleons sometimes ran south of the Bermudas,...
Ngày tải lên: 21/02/2014, 14:20
Báo cáo "Evolution of holocene depositional environments in the coastal area from the Tien river to the Hau river mouths " pot
... rate of 75m/year. This means that sea-level rising during the Holocene was not the same. During the Early Holocene sea-level rose slower than in the Middle Holocene (7Ky-5Ky). From 5Ky to 1.5Ky ... progradation from delta front into delta plain. Due to these sand ridges delta plain in study area has a typical wave relief with the ages younger seaward. Sands in these sand ridges always are ... clay, coming from the Mekong river. A depositional balance in the Early Holocene and excess of sediment supply in the Late Holocene had proved that in all time deposit supplied by the Mekong...
Ngày tải lên: 05/03/2014, 16:20
Báo cáo khoa học: Role of the hinge peptide and the intersubunit interface in the swapping of N-termini in dimeric bovine seminal RNase pptx
... located in regions different from the hinge loop 16–22. In the search for the region primarily involved in the swapping, we focused our attention on the interface between the subunits. In a previous ... J. Biochem. 270) Ó FEBS 2003 Role of the hinge peptide and the intersubunit interface in the swapping of N-termini in dimeric bovine seminal RNase Carmine Ercole 1 , Francesca Avitabile 1 , ... a recombinant sample shows that it folds mainly in the MẳM form, then undergoes interconversion into the MxM form, reaching the same 7 : 3 equilibrium ratio. To investigate the role of the regions...
Ngày tải lên: 16/03/2014, 23:20
Research " AUDITING IN THE DATA PROCESSING ENVIRONMENT — THE EVOLVING ROLE OF THE INTERNAL AUDITOR " ppt
Ngày tải lên: 23/03/2014, 05:23
Alice’s Adventures in WonderlandBy Lewis Caroll (1865)Download free eBooks of classic literature, books and novels at Planet eBook. Subscribe to our free eBooks blog and email newsletter..All in the Golden AfternoonAll in the golden afternoon Full ppt
... hat,’ the King said to the Hatter. ‘It isn’t mine,’ said the Hatter. ‘Stolen!’ the King exclaimed, turning to the jury, who in- stantly made a memorandum of the fact. ‘I keep them to sell,’ the ... being run over; and the moment she appeared on the other side, the puppy made another rush at the stick, and tumbled head over heels in its hurry to get hold of it; then Alice, think- ing ... going to begin again, it was very pro- voking to nd that the hedgehog had unrolled itself, and was in the act of crawling away: besides all this, there was generally a ridge or furrow in the...
Ngày tải lên: 24/03/2014, 00:20
The Million Person Gap: The Arab Population in the West Bank and Gaza docx
... documents from the CEC and all mathematical calculations based on them are presented in their entirety in Appendix F.) Areas for Further Revision in the PCBS Forecast By changing some migration ... of the population below 18 in the West Bank and 48.3% below 18 in Gaza, the 1.3 million adult residents would indicate a total population in the Territories of 2.34 million people. cxxix (The ... delineated. If the PCBS removes these groups from its population base, its birth projections will fall into line with figures recorded by other PA agencies, including the agencies that the PCBS itself...
Ngày tải lên: 29/03/2014, 08:20
Báo cáo khoa học: Towards understanding the functional role of the glycosyltransferases involved in the biosynthesis of Moraxella catarrhalis lipooligosaccharide ppt
... irradiating each of the anomeric signals in turn to obtain the 1 H chemicals shifts of the corresponding remaining ring protons. Again, assignment of the Kdo residue was possible from examination ... to the (1 fi 4) chain and also to the (1 fi 6) chain in serotype B strains. Lgt4 (present only in serotypes A and C), then adds an a-(1 fi 2)- GlcNAc to the (1 fi 4) chain instead of Glc. Lgt2 A (in serotype ... strains, there is an a-d-GlcNAc residue with a (1 fi 2) glycosidic link- age on the (1 fi 4) chain. To further investigate the function of Lgt4 and to explore the interrelationship between the...
Ngày tải lên: 30/03/2014, 08:20
Báo cáo khoa học: Regulation of the muscle-specific AMP-activated protein kinase a2b2c3 complexes by AMP and implications of the mutations in the c3-subunit for the AMP dependence of the enzyme docx
... Lipofectin reagent, according to the manufacturer’s instructions (Invi- trogen). Immediately prior to the lysis, the cells were sub- mitted to hyperosmotic stress by incubating them for 30 min with ... as we and others have not been able to detect any c3 mRNA or protein in this tissue [23,25]. In addition, it is possible that the antibody binding itself interferes with the AMP-bind- ing properties ... fold activation of the enzyme by 200 lm AMP remained unchanged in compari- son to the wild-type complex. The mutations in the C-terminal Bateman domain of c3 (H453R and R454G), on the other hand, substantially reduced...
Ngày tải lên: 30/03/2014, 08:20
Báo cáo khoa học: Salt-inducible kinase-1 represses cAMP response element-binding protein activity both in the nucleus and in the cytoplasm pdf
... in bold. The basic residues in domain 3B are indicated by underlines. The similarity between SIK1 and SIK2 in domain 3A, the N-terminal half of domain 3, is higher than that in domain 3B, the C-terminal ... zipper domain (b-ZIP) minus CREB [CREB (S): (right panel)] were investigated by using the Gal4 DNA-binding domain-linked assay. Cells were transformed with the Gal4 DNA-binding domain-linked CREB ... another shuttling kinase, is involved in the regulation of translation initiation by activating p70 S6 kinase and phosphorylating eIF-4E-binding protein [52]. When FRAP was restricted to the...
Ngày tải lên: 30/03/2014, 15:20
Báo cáo khoa học: Role of the N- and C-terminal regions of the PufX protein in the structural organization of the photosynthetic core complex of Rhodobacter sphaeroides pptx
... the role of the C-terminal amino-acid residues of the LH1 a polypeptide in the organization of the LH1–RC complex [12]. In the present work, we have investigated the possible involvement of the ... protein–protein hydrophobic interactions are made by the Pu fX N-terminus. In the case of the longest N-terminal deletion (strain PufXD 2)26 ), the PufXD 2)26 protein i s not detectable in the core ... the cyt bc 1 in the presence of mutated PufX protein The role of the PufX protein in facilitating the ubiquinone/ ubiquinol exchange between the Q B site of the RC and the ubiquinone pool has...
Ngày tải lên: 31/03/2014, 09:20
d. Hadn''''t it been b 41. The talks in the classroom, in the corridor and in the schoolyard do not pdf
... a 15. They …………. all kinds of sackcloth. a. produce b. do c. audit d. deposit > a 16. They used to go skiing in the mountain every winter, but for the past five years. a. they don’t ... find / to buy / trying / to travel b. see / wasn’t / to find / to buy / trying / to travel c. to see / wasn’t / to find / buy / trying / to travel d. seeing / am not / to find / buy / trying ... c. in order to d. so that b 14. the monthly salary, he has no income. a. Leaving aside b. Not counting c. Let alone d. Apart from d 15. There has been so much media of the coming...
Ngày tải lên: 18/06/2014, 17:20
báo cáo hóa học: " Hypoxia silences the neural activities in the early phase of the phrenic neurogram of eupnea in the piglet" docx
... neurograms during eupnea and compared them with those of gasping in order to investigate the similarities between these patterns. Our preliminary data indicated that the patterns during early and ... influence phrenic neurons responsible for the neural activities in the late phase of the phrenic neurogram dur- ing inspiration. In addition, it also significantly increases the duration of the ... during maturation. The dominant burst type activ- ities disappeared during the early phase of the phrenic neurogram although the burst activity and the continuous activity remained, but both them...
Ngày tải lên: 19/06/2014, 10:20
báo cáo hóa học: " Mild solutions for a problem involving fractional derivatives in the nonlinearity and in the non-local conditions" ppt
Ngày tải lên: 21/06/2014, 02:20
Báo cáo toán học: "Remarks on the singular extension in the C*-algebra of the Heisenberg group " docx
Ngày tải lên: 05/08/2014, 10:20