... of the skill employed, of the genius evinced in the composition.'' He further explained, ``After perusal of the one class, we think solely of the book ± after reading the other, chie¯y of the ... compares the sound of the maelstro m with that of the buffalo moaning, and the story ends with the setting moon, an analogue for the setting sun The old Norwegian guide who survives his brothers ... author The former class leads to popularity ± the latter to fame In the former case, the books sometimes live, while the authors usually die; in the latter, even when the works perish, the man...
Ngày tải lên: 01/11/2013, 09:20
The State and the Novel
... allusions with her political theme The most obvious of these is the dynamic of the thriller, which leaves Grace’s fate unclear until the The State and the Novel 35 final page The other is an extended allusion ... of the media; a sequence of stock-market scandals; the poisoning of the food chain in the pursuit of profit; and the displacement of aesthetic values in the art world The chief villains are the ... upper and middle class, the husband, the father, and the male generally’.29 Were either of these assumptions beyond question, the satirical thrust of Malcolm Bradbury’s The History Man (1975)...
Ngày tải lên: 01/11/2013, 10:20
... Vrp1p [23] We therefore asked whether using the same technique to anchor C-Vrp1p364)760 (CABS) to membranes would restore function in the absence of the LBD C-Vrp1p364)760 was tagged at the C-terminus ... C-Vrp1p760)817 (which contains the LBD only) could not (data not shown) Because the LBD is rather short, comprising 57 residues, we then fused the DNA encoding the LBD inframe to sequences encoding ... proteins, but we expect that the relative expression level of the tagged proteins is indicative of that of the equivalent untagged proteins To assess the function of these proteins in endocytosis...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Characterization of the interaction between the plasma membrane H+-ATPase of Arabidopsis thaliana and a novel interactor (PPI1) doc
... H+-ATPase in the PM and stimulate its activity [22], suggested that the site of interaction with the PM H+-ATPase was localized in the N-terminus of PPI1 To further characterize the biological ... downstream of the first 88 amino acids of PPI1 may participate in the interaction with the H+-ATPase and makes PPI1588His6 a suitable tool to study the mechanism of action of PPI1 The analysis of the pH ... restriction sites The resulting plasmid was transferred into E coli strain XL10 and the frame and the identity of the cloned fragment verified by sequencing The construct with the N-terminal portion...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khoa học: Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family docx
... sequence identity The four PDGFs are inactive in their monomeric forms They share the same receptors; the PDGF receptor-a and -b These receptors dimerize when the dimeric PDGF binds The receptors ... the cytoplasm and nucleus, a feature also described for PDGF-B [31,32] The function of these two PDGFs in the nucleus is unclear The region N-terminal of the CUB domain in PDGF-C and PDGF-D The ... as the growth factor domain Although the four growth factor superfamilies have a common topology, they differ in the number of disulfide bonds, the interfaces used to form the dimers, and the...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo Y học: Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation ppt
... h with the indicated NAMI-A concentration (NAMI-A) Cells were then stimulated for h with medium M199 containing either 100 nM PMA (B) or 10% fetal bovine serum (C), in the presence of the indicated ... expression To establish whether the decrease in c-myc mRNA expression elicited by NAMI-A might have occurred at the transcriptional level, we assessed the rate of transcription of the c-myc gene by using ... the immunoblotting analysis correspond to c-myc immunoreactivity are shown in the panel B ECV304 cells and that such a condition plays a key role in the alteration of the growth behavior of these...
Ngày tải lên: 21/02/2014, 01:21
Báo cáo khoa học: Purification and structural analysis of the novel glycoprotein allergen Cyn d 24, a pathogenesis-related protein PR-1, from Bermuda grass pollen pot
... sequences of Cyn d 24 The numbers on the right of the figure indicate the positions of the nucleotide sequence The numbers on the left of the figure indicate the positions of the deduced amino acid ... to the N-terminal portion of the allergen Based on this partial sequence, two specific primers were designed and used together with the anchor primer AP2 to obtain the 5¢ and 3¢ portions of the ... has been suggested to be the result of degradative reactions, rather than imperfect biosynthesis [13] Of the plant allergens listed in the official allergen database of the IUIS, about 25% belong...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans ppt
... cross-talk between the EGFR and the androgen receptor in prostate carcinoma cells [50] The interplay between decorin and the EGFR is further underscored by osteosarcoma cells which escape the decorin-suppressing ... of these transformed cells are not dependent on TGFb for their growth, it was hypothesized that another receptor system had to be involved, insofar as decorin is a soluble proteoglycan One of the ... unique features such as the organization of disulfide bonds at their N- and C-termini, with the cysteine residues following a class-specific topology, and on the basis of their genomic organization,...
Ngày tải lên: 15/03/2014, 23:20
Báo cáo khoa học: Differential expression pattern of the novel serine⁄threonine kinase, STK33, in mice and men doc
... rather reflects synchrony to other events of the spermatogenesis For instance, the mechanisms unleashing the pass of the haploid germ cells through the tight junctions from the adluminal to the ... has been argued that the germ cells themselves may signal the Sertoli cells their entry to meiosis, triggering their transport through the blood–testis barrier [43] On the other hand, apoptotic ... for the negative controls The resolution varied between and lmÆpixel)1 depending on the size of the section of the image The Adobe photoshop program was used to produce merged images in the double-staining...
Ngày tải lên: 16/03/2014, 23:20
of mice and men a comprehensive comparision of the novel and
... than the novel for several reasons The novel gave good descriptions of the characters but I learned more about them and the story form the film because I was watching and listening to them, rather ... to be the character I had envisioned Overall, the casting and photography was excellent Another reason why I liked the film better was because of its dramatic conclusion At the end of the novel ... George has Carlson's gun and then we know what is going to happen At the end of the film, we don't know George has the gun and we can't see that he is holding the gun to the back of Lennie's head...
Ngày tải lên: 21/03/2014, 22:48
the chamber a look into the novel and film
... was the minor but Cano-4highly significant changes of the plot In the novel, the first three chapters of the book describe the events leading up to the bombing in detail The movie starts with the ... than the film The film basically focused on the relationships between the characters which left out much of the novel's detailed plot The major part of the novel's detail which was left out of the ... differences between themselves in the novel and the film The melodramatic film takes away from the novel's descriptive plot The first major difference I noticed was in the level of detail The novel seemed...
Ngày tải lên: 21/03/2014, 22:53
princeton university press the novel volume 1 history geography and culture may 2006
... with the other cultures that derive from the ancient sources of the Near Eastin other words, the Bronze Age cultures with their invention of writing.31 For example, the earliest example of the ... for both the contending parties in the struggle, the Fulani and the Bambara Each time the griots are playing to a specic but varying audience They live by the responses of that audience; they travel, ... repeated by the audience of neophytes and members (their guides), and then the whole process is repeated twice yet again by other Speakers The time taken varies with the Speaker and the degree...
Ngày tải lên: 11/06/2014, 16:27
báo cáo khoa học: "Bilateral adrenocortical carcinoma in a patient with multiple endocrine neoplasia type 1 (MEN1) and a novel mutation in the MEN1 gene" potx
... account the severity of the PHPT symptoms, the circulating PTH and calcium levels, the presence of MEN1-associated endocrinopathies, especially the Zollinger-Ellison syndrome (ZES) and the patient’s ... between 10 and 60% [13], while their symptoms depend on the type and the amount of the pituitary hormone secretion and/or the compression effects due to the size of the tumour [26] Pituitary tumours ... Athens, Athens, Greece BioGenomica Genetic Tests Center, Athens, Greece Authors’ contributions JG performed the operation and contributed to the preparation of the manuscript; ND assisted to the...
Ngày tải lên: 09/08/2014, 01:24
Báo cáo y học: " Ancient, independent evolution and distinct molecular features of the novel human T-lymphotropic virus type 4" pot
... and HTLV-3 [27] The absence of PDZ suggests that the HTLV-4 Tax may be more phenotypically similar to the HTLV-2 than the HTLV-1 Tax Furthermore, the high amino acid identity of the Tax4 and Tax2 ... either with or without the enforcement of the global clock constraint with the program PAML [72] The PTLV evolutionary rate assuming the global molecular clock model was estimated by using the ... [18-20,23,31,34,35] The distal 21-bp repeat element found in HTLV-1 and HTLV-2 is absent from the HTLV-4(1863LE) genome (Fig 7) Others have shown that deletion of the middle, rather than the distal 21-bp...
Ngày tải lên: 13/08/2014, 05:21
logico-semantic relations and their realization in chapter 5 white fang and the indians in the novel white fang by jack london
... of the study The study is organized around parts: Part A states the reasons for choosing the topic, the aim, research questions, the scope, data collection, the methods of the study, and the ... eliminates the meanings possible to that context other than those the form can signal: the context eliminates from consideration the meanings possible in the form other than those the context ... to the nature of the participants, their statuses and roles: what kind of role relationships of one kind or another, both the types of speech role that they are taking on in the dialogue and the...
Ngày tải lên: 02/03/2015, 14:32
Logico-semantic relations and their realization in chapter 5 White fang and the Indians in the novel White fang by Jack London
... INTRODUCTION Rationale Aim of the study and Research questions Scope of the study Data collection Methods of the study Design of the study PART B: DEVELOPMENT CHAPTER THEORETICAL BACKGROUND 1.1 ... CHAPTER “WHITE FANG AND THE INDIANS” IN THE NOVEL “WHITE FANG” BY JACK LONDON 2.1 Introduction 28 2.2 The context of the chosen text 28 2.3 Contextual configuration of the text 29 2.3.1 Field ... CONCLUSION Recapitulation 43 Implications of the study 43 Suggestions for further study 44 REFERENCES 46 APPENDICES References Bloor, Thomas & Meriel (1995), The Functional Analysis of English, Oxford...
Ngày tải lên: 10/08/2015, 19:51
The novelty and surface to volume ratio dependent electron band structure in semiconductor nanowire
... direction are the most stable They also found that the cage-like nanowires have better electrical conducting properties Getting these results, we have the ideas that the contributions of the surface ... area A (in nm2) and the number of atoms N in the supercell in our calculations The dimension D is defined as the largest distance between the terminating hydrogen atoms in the cross section plane ... bond), as the linking molecules to the SiNW.[4] In Ref [5], N Lorente, et al studied the SiNW grown along the direction with a bulk Si Core using the density-functional calculations They found...
Ngày tải lên: 09/09/2015, 18:55
The NR4A orphan nuclear receptors are target genes of the novel drug c1 in cancer cells and potential mediators of drug induced apoptosis
... regulation of the MOMP In the first model, a ’pore’ is formed by the ANT in the inner mitochondrial membrane and the VDAC in the outer mitochondrial membrane and cyclophilin D in the matrix (Green ... nuclear receptors on the other hand respond to dietary lipids, and the concentration of these lipids is not under a well governed feedback control Also these receptors bind their lipid ligands ... the upstream caspase caspase which can then cleave downstream caspases like caspase The extrinsic pathway may also recruit the mitochondrial pathway by cleaving the BH3-only protein BID and the...
Ngày tải lên: 14/09/2015, 14:04
The dynamics of literary representation and interpretation in a multilingual environment a study of selected malaysian and singaporean novels in english
... meanings are possible In other words, the choice of the text depends very much on the dialogic quality of its language The theoretical basis for the discussion of the text will be the notion of heteroglossia ... lekas! … (152) The question in the mind of the reader would be ‘In what language did they interact?’ The utterance “‘Baik-lah, lekas!’” gives the reader the answer The chances are the heiho spoke ... example is The Dark Backward (1958) by Eric Lambert: The voices spoke again Someone said in Malay: “They will take the right hand track on the other side of the estate.” The estate is free of the Hantu...
Ngày tải lên: 16/09/2015, 08:30