the b cell response and production of antibodies

Báo cáo y học: " An association between the acute phase response and patterns of antigen induced T cell proliferation in juvenile idiopathic arthritis" ppt

... value of proliferation to the same antigen in the peripheral blood compartment (b) The proliferative responses to SLO and TT observed in the patients in the diverse group (n = 17) Responses in the ... proliferation and standard deviations of triplicate values (b) The proliferative responses to SLO and TT observed in the patients in the restricted group (n = 19) Responses in the peripheral blood differed ... for the kind gift of the Act-1 antibody We are grateful to Professor Mike Salmon and Professor Chris Buckley for critical reading of the manuscript We acknowledge the financial support of the...

báo cáo hóa học:" Characterization of the tumor marker muc16 (ca125) expressed by murine ovarian tumor cell lines and identification of a panel of cross-reactive monoclonal antibodies" docx

Danh mục: Hóa học - Dầu khí

... CAOV-3 cells (Fig 4B) The binding of 618F, 653F and VK-8 to the OVCAR-3, SKOV-3, and CAOV-3 cells was comparable Considering the demonstrable specificity of 618F and 653F for MUC16 and their ability ... were obtained with both the 618F and 653F antibodies (Fig 6c and 6d) Discussion Figure ting Identification of soluble Muc16 and MUC16 by Western blotIdentification of soluble Muc16 and MUC16 by ... Expression of cell surface and intracellular Muc16 in the four MOVCAR cell lines was determined by flow cytometry using the 618 F antibody The mean fluorescence intensity for the binding of 618F to the...

Báo cáo y học: " Ageing, autoimmunity and arthritis: Senescence of the B cell compartment — implications for humoral immunity" pptx

Danh mục: Báo cáo khoa học

... chains and Ig-α/β marks the transition to the immature B cell stage Immature B cells are the earliest cells in the lineage that express a bona fide antigen specific B cell receptor (BCR), and therefore ... individual pro -B and pre -B cells are similar between aged and young mice, but total BM RAG expression is reduced in aged animals because of reduced numbers of pre -B cells [18] Nevertheless, the relative ... gradual loss of naïve follicular B cells, but not of MZ or B1 B cells Recent studies conducted in our laboratory also suggest that reduced influx of B cells from the BM drives the selection of antigen-experienced...

Tài liệu Báo cáo khoa học: The role in the substrate speciﬁcity and catalysis of residues forming the substrate aglycone-binding site of a b-glycosidase docx

Danh mục: Báo cáo khoa học

... NPbfuc NPbglc NPbgal NPbxyl MUbglc NPbfuc NPbglc NPbgal NPbxyl MUbglc NPbfuc NPbglc NPbgal NPbxyl MUbglc NPbfuc NPbglc NPbgal NPbxyl MUbglc NPbfuc NPbglc NPbgal NPbxyl MUbglc NPbfuc NPbglc NPbgal ... inﬂuence the binding of the ﬁrst glucose unit of the aglycone On the other hand, M453 may be positioned in subsite +2 because these residues inﬂuence the binding of the second glucose unit of the ... part of the aglycone-binding site of Cpbgly [22] In order to compare the aglycone-binding sites of these b- glycosidases, the effect of the aglycone size on the binding of several alkyl b- glucosides...

Báo cáo khoa học: Degradation of chitosans with chitinase B from Serratia marcescens Production of chito-oligosaccharides and insight into enzyme processivity docx

Danh mục: Báo cáo khoa học

... of two chitosans with FA of 0.65 and 0.30 The relative intensities of the a b- anomers correspond to the equilibrium ratio between the two anomers, which is 60 : 40 at pH 45 [39] The a- and b- anomer ... of the substrate-binding groove is extended by the aromatic surface of a putative chitin-binding domain The crystal structure of ChiB further suggests that the active site cleft is partially blocked ... the glycon side of the catalytic centre The observation of longer oligomers early during the reaction may seem to contrast with the putative exo-activity of the enzyme, but can be explained by...

Báo cáo khoa học nông nghiệp " Effects of Stocking Biomass on Growth, Survival and Production of the Two Sizes of Clam Meretrix lyrata Cultured in the Intertidal Areas And Notes on Hatchery Production of Clam Spat " pot

Danh mục: Báo cáo khoa học

... uncontrollable and variable, stocking biomass becomes an important factor to increase the growth and production The objective of this research was to evaluate the effect of stocking biomass of the two ... 1993) and thus contribute to the sustainable aquaculture development Clams belong to bivalve shellfish but they are different from the others by dwelling on the bottom Researches have been conducted ... Production and quality The production of clam derived from both growth and survival There was a positive relationship of the clam production and stocking biomass although the growth and survival...

Báo cáo nghiên cứu khoa học " CLAM CULTURE DEVELOPMENT IN THE INTERTIDAL AREA: EFFECTS OF STOCKING BIOMASS ON GROWTH, SURVIVAL AND PRODUCTION OF THE TWO SIZES CLAM Meretrix lyrata " docx

Danh mục: Báo cáo khoa học

... growth and production The objective of this research was to evaluate the effect of stocking biomass of the two sizes of M lyrata on growth performance and survival to enhance the production and profit ... The estimation of the economic benefit of clam cultured in the intertidal areas is showed in table The net profit is calculated based on the output cost and input cost and price of the clam The ... However, the increasing of the biomass gained as well as final production indicated that benefit can be obtained if the appropriate stocking biomass was determined The economics of culture therefore...

Báo cáo y học: "Balance between survivin, a key member of the apoptosis inhibitor family, and its specific antibodies determines erosivity in rheumatoid arthritis" ppt

Danh mục: Báo cáo khoa học

... Double-wave reading at 450 and 570 nm was used and the difference of absorbances was calculated The obtained absorbance values were compared with the serial dilution of recombinant survivin and ... USA) The results were analysed using the CELLQuest software (Becton Dickinson) Proliferation of THP-1 cells was assessed by incubating the cell suspension with the test substance for 48 hours The ... expressed the level of survivin and antibodies against survivin in the blood, in synovial fluid samples, as well as in cell lysates as the mean ± standard error of the mean The survivin levels in the...

Báo cáo y học: "No evidence for an association between the -871 T/C promoter polymorphism in the B-cell-activating factor gene and primary Sjögren''''s syndrome" pptx

Danh mục: Báo cáo khoa học

... specific pattern of antibody secretion, including anti-SSA/SSB autoantibodies, rheumatoid factor, and serum gammaglobulin and IgG levels Likewise, the absence of genetic involvement of BAFF in RA or ... influence BAFF level Surprisingly, no correlation was observed between BAFF polymorphism and BAFF mRNA levels in patients with pSS The absence of concordance between BAFF protein and mRNA regarding the ... increased BAFF mRNA level in blood monocytes We therefore investigated the association between BAFF -871 T/C polymorphism and BAFF expression, and focused first on the correlation between BAFF polymorphism...

Báo cáo y học: " Importance of spliceosomal RNP1 motif for intermolecular T-B cell spreading and tolerance restoration in lupus" pptx

Danh mục: Báo cáo khoa học

... activate B cells to produce anti-RNP1 antibodies (Abs) These B cells then bind and process the RNP1 epitope present within RNP1+ proteins, such as U1-70K (in blue) and U1-A (in green), but also the ... proteins by antibodies from autoimmune mice and patients [[13]; and references therein] In the present study, we show that antibodies elicited after immunizing a rabbit with the peptide 131–151 of the ... antibodies Antibodies generated in outbred rabbits to peptide 131– 151 of the U1-70K protein react with the cognate protein and with other spliceosomal proteins We then questioned whether antibodies...

Báo cáo y học: "Effect of methotrexate and anti-TNF on Epstein-Barr virus T-cell response and viral load in patients with rheumatoid arthritis or spondylarthropathies" ppt

Danh mục: Báo cáo khoa học

... T -cell response Correlation between the Epstein-Barr virus viral load and Epstein-Barr virus-specific T -cell response Correlation between the number of IFNγproducing T cells and the Epstein-Barr ... least 50 SFCs/106 PBMCs and exhibited at least twofold the mean value of the background (per million PBMC) The median number of IFNγ-producing PBMCs in the presence of medium alone (background) was ... proportion of subjects with positive EBV-specific IFNγ-producing T cells in PBMCs, the mean number of SFCs or the SFC distribution Two studies have assessed the EBV-specific T -cell response in PBMCs of...

báo cáo khoa học: "MeRy-B: a web knowledgebase for the storage, visualization, analysis and annotation of plant NMR metabolomic profiles" potx

Danh mục: Báo cáo khoa học

... enlarge the MeRy -B knowledgebase by the inclusion of libraries of reference compounds from MeRy -B users or from other available libraries Conclusion MeRy -B is a web-based application and database ... contributions ADD and AM initiated the project HFD, DJ and LG designed the DB LG and DJ designed the web interface and implemented the DB and associated tools and developed the source code of the ... visualization and export of the data already stored into the database: the search Spectral Data and search Compound under the tab labeled Data consultation and the Query builder under the Tools menu The...

Báo cáo y học: " Successful long-term monotherapy with rituximab in a patient with chronic lymphocytic leukemia of the B-cell-lineage: a case report" pdf

Danh mục: Báo cáo khoa học

... pancytopenia Therapy with alemtuzumab was considered, but preference was given to rituximab because of the less severe compromise of the cellular immune system by rituximab, and because of the possibility ... cyclophosphamide and rituximab 375 and leucocyte Course of Course of hemoglobin, leucocyte and thrombocyte numbers under therapy with chlorambucil, fludarabine, cyclophosphamide and rituximab 375 and 600 ... respectively The main drawback of rituximab monotherapy observed so far is the limited response to the induction therapy in pretreated patients [5] Hainsworth and coworkers did report Page of (page number...

Báo cáo y học: "Bench-to-bedside review: Functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis" ppsx

Danh mục: Báo cáo khoa học

... initiated by binding of fragments of bacterial cell walls, and even whole bacteria, to LBP (a serum acute phase protein) Complexes of LBP and bacterial constituents may then easily bind to membrane ... hemocyte or amebocyte, at the site of local injury The amebocyte simultaneously performs the dual functions of both platelets and phagocytic cells The amebocyte will recognize the presence of bacterial ... activated by the thrombin–thrombomodulin complex The TAFIa that is generated removes basic lysine and arginine residues from the carboxyl terminus of peptides and proteins In the case of fibrin,...

Báo cáo sinh học: " Protection against the allergic airway inflammation depends on the modulation of spleen dendritic cell function and induction of regulatory T cells in mice" docx

Danh mục: Báo cáo khoa học

... from the spleen, incubated with FITC-labeled CD11c (eBioscience Inc.), PE-labeled antiCD80 (B7 -1) mAb (eBioscience Inc.), and PE-labeled antiCD86 (B7 -2) mAb (Southernbiotech) on ice for 30 min, and ... thickness of small airway walls and the number of infiltrated eosinophils around the airway increased, eosinophils appeared within the lumen of the airway, and goblet cell hyperplasia and hypertrophy ... levels of Figure Serum levels of OVA-specific IgE (A) and the number of eosinophils in bronchoalveolar lavage (BAL) fluid (B) in PBS-vaccinated mice sensitized and challenged with PBS, PBS-vaccinated...

Guide to the Secure ConfiguratGuide Configuration and Administration of Microsoft Exchange

Danh mục: An ninh - Bảo mật

... mailboxes and consists of messages sent from user to user They are accessible by the mailbox owner and others for whom access has been allowed The public store is used for newsgroups and other objects ... mailbox-by-mailbox basis, select the Recipients container and then the mailbox Select File/Properties and the “Protocols” tab Highlight HTTP (Web) and click on “settings” to enable or disable ... ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE Please keep track of the latest security patches and advisories at the Microsoft security bulletin page...

Tài liệu Báo cáo khoa học: Structural insights into the substrate speciﬁcity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria ppt

Danh mục: Báo cáo khoa học

... along the extended backbone of residues 65–64 and is partly exposed to the solvent (Fig 2B) On the other hand, the P3 moiety of E-64 in each of the of the two ervatamin-C molecules in the asymmetric ... in the study of mechanism exempliﬁed by a comparison of the catalytic-site structure and characteristics of cathepsin B and papain pH-dependent kinetics of the reactions of cathepsin B from bovine ... transfer of the proton from the catalytic Cys present at the N-terminus of the helix to the His of the dyad [19,50,51] The ﬁrst stage of catalysis is mediated by the highly active thiolate ion of the...

Tài liệu Báo cáo khoa học: "Accumulation of Lexical Sets: Acquisition of Dictionary Resources and Production of New Lexical Sets" pdf

Danh mục: Báo cáo khoa học

... in, the bigger the number becomes 2.2 Implementation of production Studying the algorithms for the categories above shows they may make use of many c o m m o n basic operations As an example, the ... Acknowledgement The author is grateful to the French Government for her scholarship, to Christian Boitet and Gilles Sdrasset for the suggestion of the theme and their help, and to the authors of the DRs ... acquire it becomes We propose here a measure for this Briefly, the structure complexity (SC) of a dictionary is equal to the sum of the number of elementary information types and the number of set...

Tài liệu Obesity guidance on the prevention, identification, assessment and management of overweight and obesity in adults and children ppt

Danh mục: Cao đẳng - Đại học

... change should be explored Possible barriers include: − lack of knowledge about buying and cooking food, and how diet and exercise affect health − the cost and availability of healthy foods and opportunities ... prevention and management of obesity should be a priority for all, because of the considerable health benefits of maintaining a healthy weight and the health risks associated with overweight and obesity ... organisations such as the NHS and local authorities, should address the prevention and management of obesity, because of the considerable impact on the health of the workforce and associated costs...

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Tài liệu YOUR GUIDE TO THE SCIENCE, HISTORY, ART AND TECHNOLOGY OF PAPERMAKING pdf

Danh mục: Tự động hóa

... into the back of the mold Then list the mold off the blotter Y paper should stick to the blotter! our Place another blotter sheet on top of the new paper and use the rolling pin to squeeze out the ... (continued) Cut the tip off Tie the bead or macaroni to the end of the string Thread the paper bell onto the string Rest the bell on the macaroni Keep tying the beads or macaroni and adding the bells till ... Then remove the paper clip hook Using masking tape, secure the top of the left tab of the sample to the table of desk edge Hang the paper clip hook through the hole as shown below Bed the tab...

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