... further analysis ofthe magnitude ofthe demand differences between products consumed today andthe potential demand for organic products in the Transkei andthe Ciskei is presented in Figure and ... was drawn randomly from rural and urban locations in the two main regions ofthe Eastern Cape, namely the former Transkei homeland area andthe former Ciskei homeland area By means of structured ... that (i) They are healthy and nutritious (83.1% of consumers); (ii) They are good for the management of illness (35.4% of consumers); (iii) They have a better appearance and taste (30.8% ofthe consumers)...
... disease, the primary pathology is in the kidney [1], the major site of Gb3 synthesis in man [11], and in the heart, possibly due to the association of Gb3 synthesis with the microvasculature GSL synthesis ... v) per 100 lL of plasma and then partitioned against ⁄ volume of water The lower phase was dried under a stream of nitrogen gas and then the residue was dissolved in chloroform The sample was ... considered that the increased renal Gb3 ofthe Fabry mouse might extend to the glomerulus to provide a model ofthe human disease In the cortex of wild-type kidney, subpopulations of renal tubules...
... Commissioner at the time, Margaret Hamburg, drew upon the strong political will ofthe mayor and others to gather resources and mobilize a comprehensive response to the resurgence of TB in the city The city ... become the principal operating agency of both the National Academy of Sciences andthe National Academy of Engineering in providing services to the government, the public, andthe scientific and ... represent the formal positions ofthe planning committee, the Forum, the IOM, INSA, or ICMR; however, they have provided valuable input to the Forum and to the IOM andthe workshop contributors as they...
... filter’’ based on the lower two quartiles ofthe CO and C2Cl4 mixing ratios was employed to mitigate the effect of pollution Figure shows the CO mixing ratios as a function of latitude and their frequency ... close to the limit of detection ($30 ppt at 2s for 5-min averages) and in part due to the homogeneity ofthesourcesand sinks in the UT This north – south latitudinal behavior for these gases ... interpret these in light of present measurements Given the great paucity of available data, many assumptions and extrapolations are necessary and are noted Estimates ofthe global sourcesof OVOC...
... and their specific implications on land use and other pressures, and their contribution to the solution ofthe problem of climate change The Working Group on Decoupling provides a rationale and ... resources, their processing into materials and products andthe subsequent use and discarding ofthe products The figure emphasizes the coherence ofthe production consumption chain and illustrates ... specific resources, i.e metals, a more detailed understanding ofthe anthropogenic flows and stocks and their potential scarcity The Working Group on Biofuels focuses on the specific topic of biofuels,...
... PT thermal energy management The experiences ofthe pinch analysis are incorporated in the Green Brewery Concept The concept calculates a generic list of heat sourcesand heat sinks based on the ... profile are the parameters that influence thechoiceof new supply equipments to the largest extent 3.1 Results and Discussion Description ofthe case studies Figure shows a general flowsheet of ... need to be entered The calculation ofthe thermal energy demand is done on a process level based on the production data and technologies to allow for a detailed energy balance ofthe status quo in...
... ofthe phosphate donor in the dNK family, there is a domain in hTK1 and Uu-TK that contains a structural zinc atom and lasso-like loop In the feedback inhibitor complexes of Uu-TK and hTK1, the ... dotted lines The tight binding site for the 2¢ position between the main chain of Lys180-Ile181 and Met21 Any substitution at the 2¢ position hinders proper closure ofthe lasso, and thereby weakens ... substrates and have the highest activities The iodo atom has the same van der Waals radius as the methyl group of thymine, andthe corresponding analogue has an activity comparable to that of dT The...
... and their specific implications on land use and other pressures, and their contribution to the solution ofthe problem of climate change The Working Group on Decoupling provides a rationale and ... resources, their processing into materials and products andthe subsequent use and discarding ofthe products The figure emphasizes the coherence ofthe production consumption chain and illustrates ... specific resources, i.e metals, a more detailed understanding ofthe anthropogenic flows and stocks and their potential scarcity The Working Group on Biofuels focuses on the specific topic of biofuels,...
... and risks of usual care versus the expected benefits and risks ofthe trial after pooling all arms, and that the decision point always comes before randomization and hence is independent ofthe ... and not upon the value of any single arm The principle of ‘equal uncertainty between the arms ofthe RCT’ must be replaced with the principle of a reasonable ‘expected value’ for the participant ... amounts of data about the drug, and has eliminated the least promising agents before the design process for randomized controlled trials occurs Design bias Design bias, on the other hand, occurs...
... insight into the relative importance of barriers to the implementation of change, andthe trade-offs people make between barriers on the one hand and facilitators on the other hand DCE therefore ... number of choices Each choice consists of two or more hypothetical profiles, and for each choice, people are asked which profile they would choose Forcing people to make choices and trade-offs ... Although there is no 'gold standard' for prioritising potential barriers and facilitators to the implementation of change, theoretically, DCE would be the method ofchoice However, the feasibility of...
... insight into the relative importance of barriers to the implementation of change, andthe trade-offs people make between barriers on the one hand and facilitators on the other hand DCE therefore ... number of choices Each choice consists of two or more hypothetical profiles, and for each choice, people are asked which profile they would choose Forcing people to make choices and trade-offs ... Although there is no 'gold standard' for prioritising potential barriers and facilitators to the implementation of change, theoretically, DCE would be the method ofchoice However, the feasibility of...
... with the effects ofthe dictatorship of 1976 - 1983 During the dictatorship, thousands of youth and adults were disappeared and, in many cases, tortured and/ or killed Their family members were often ... Questions were asked about a number of substances they used and their routes of administration These included the age of first use, and data on frequency of use “ever” and for last months, for: cannabis, ... stable jobs anddrug users who sleep during the day The small number of IDUs in the study limits what we can conclude about them The fact that the sample is not a probability sample andthe known...
... increasing knowledge and awareness of HCV risk behaviours andthe consequences of HCV infection, introducing the rationale and structure ofthe intervention to the subject, and assessing the individual's ... contributed to the protection ofthe validity ofthe Trial and maximising the quality ofthe data included the written protocol that was followed, the manual-guided treatment interventions, and quality ... session of EPC of those followed-up Table illustrates the number of completed sessions of EPC There was a significant difference between the two groups in terms of their engagement with the therapy...
... HIV-1 virus and whether the C-terminal region of RT played a role in the emergence ofthe Q151M MDR complex The emergence and presence of mutations in DNA pol domain, connection subdomain and RNase ... initiation of therapy, even though the viral load had been relatively high at earlier time points This raises the possibility of suboptimal use ofthe drugs contributing to the emergence ofthe Q151M ... mutations andthe sequential acquisition ofthe Q151M MDR mutations suggested that they could be facilitating the emergence ofthe Q151M MDR complex This notion is further supported by the observation...
... our demand-side intervention, the government is the social planner and hence maximizes the total social welfare, which is the sum ofthe utilities of all individuals andthe profit ofthe manufacturer.7 ... highlights the interaction between the demand-side and supply-side inefficiencies We find that the value of supply-side intervention depends on the infectiousness ofthe disease whereas the value of demand-side ... respectively Figures 2.4a and 2.4b illustrate these entities as a function ofthe coefficient of variation ofthe yield distribution ¯ (CV ) andthe infectiousness ofthe disease (R0 ), respectively,...
... Conventional drugs andthe pathways they influence have been the subject of immense interest to biologists, and there has been some headway in understanding the signal transduction pathways these drugs ... Accordingly, the great and urgent need presently is to investigate the role of each ofthe plenitude of genes and proteins important in the progression of cancer NUCLEAR RECEPTORS The nuclear ... Pervaiz, Professor, Department of Physiology, Yong Loo Lin School of Medicine, NUS Their encouragement and guidance and their critique has been of paramount importance in directing the course of the...
... compared to the alternative E1 and they should thus select E2 Let the size ofthe alignable assortment be increased to three with the inclusion ofthe brand variant E3 in the assortment The alignable ... information The aim ofthe promotion focused consumers is to maximize the presence of positive attributes and minimize the absence of positive attributes in their chosen brand variant The three brand ... feature There were two alignable features in the brand variants - one contributing to the alignability ofthe assortment along the positive scale andthe other one contributing to the alignability of...
... coined the phrase, ‘download IT to the field’, which captured our push to get IT professionals out of their cubicles and into the call centres, the trucks andthe business offices to truly understand ... over the way they use technology in their work 38 The consumerisation of IT and proliferation of easy-to-use technology services have reduced the need for centralised control of IT resources 26 The ... 34 The consumerisation of IT and proliferation of easy-to-use technology services have reduced the need for centralised control of IT resources 32 The consumerisation of IT and proliferation of...