the acute respiratory distress syndrome

... volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome The Acute Respiratory Distress Syndrome Network N Engl J Med 2000, 342:1301-1308 ... Adult respiratory distress syndrome in neutropenic patients Am J Med 1986, 80: 1022-1026 Chollet-Martin S: Polymorphonuclear neutrophil activation during the acute respiratory distress syndrome ... Pattishall EN: Aerosolized surfactant in adults with sepsis-induced acute respiratory distress syndrome Exosurf Acute Respiratory Distress Syndrome Sepsis Study Group N Engl J Med 1996, 334:1417-1421...

Ngày tải lên: 12/08/2014, 20:20

... Pulmonary hypertension The immunology of ARDS  Endothelial injury results in increased capillary permeability and the influx of protein-rich fluid into the alveolar space  Injury to the alveolar lining ... 2007 The theoretical answer: Promote alveolar recruitment  The Problem: a uniformly applied positive insufflating pressure/breath only opens some alveoli during a timed respiratory cycle  The ... collapse The immunology of ARDS the development of ARDS also involves…  Tumor necrosis factor (TNF) and other cytokines  Leukotrienes  macrophage inhibitory factor, platelet factors, and others...

Ngày tải lên: 28/10/2016, 20:23

... pathways, the p44/42 MAPK pathway and the PI 3-kinase pathway [8,10] In the present study, we investigated the signaling pathways that mediate the inhibitory effects of insulin on the expression of the ... µg/ml) The level of transcription in control cells at the 4hour time-point was made equal to one The data are the results of three experiments expressed as the mean ± SD (standard deviation of the ... autophosphorylation of the β-subunit of the receptor [8] The protein kinase domain of the β-subunit then phosphorylates tyrosine residues in insulin receptor substrate (IRS)-1, IRS-2, IRS-3, or Shc, which then...

Ngày tải lên: 12/08/2014, 18:20

... the complex network of these molecules and their inhibitors in ARDS or at risk for ARDS and their value as predictive factors Abbreviations ALI = acute lung injury; ARDS = acute respiratory distress ... know if there is a critical value over time that could predict the course of the disease in these patients However, the most interesting finding of this study is that the serum levels of the measured ... fluid (BALF) and serum levels (pg/ml) of the measured cytokines and adhesion molecules in acute respiratory distress syndrome patients (group A) whether or not they survived BALF Serum Survivors (n...

Ngày tải lên: 12/08/2014, 18:20

... of SAPS II Proning may benefit the most seriously ill subset of patients with acute respiratory distress syndrome Those in the quartile with the highest Simplified Acute Physiology Score II (SAPS ... injury and the acute respiratory distress syndrome N Engl J Med 2000, 342:1301-1308 Douglas WW, Rehder K, Beynen FM, Sessler AD, Marsh HM: Improved oxygenation in patients with acute respiratory ... invokes the standard responses of an advocate of a therapy when the clinical trial results are different than the results he had expected It is impossible to conclusively prove the negative hypothesis...

Ngày tải lên: 12/08/2014, 18:21

... December 2004 Vol No Reutershan and Ley volumes for acute lung injury and the acute respiratory distress syndrome The Acute Respiratory Distress Syndrome Network N Engl J Med 2000, 342:1301-1308 ... through the endothelium (inset C1: transendothelial migration), interstitial space, and epithelium (inset C2: transepithelial migration) to reach the alveolar space The requirement of AMs for the ... mechanism to explain the systemic consequences of ventilator-induced lung injury in patients with ARDS Anesthesiology 2002, 97:1426-1433 45 The Acute Respiratory Distress Syndrome Network: Ventilation...

Ngày tải lên: 12/08/2014, 20:20

... Care Med 2001, 27:1699-1717 Spragg RG, Lewis J: Surfactant therapy in the acute respiratory distress syndrome In Acute Respiratory Distress Syndrome Lung Biology and Health and Disease Series Volume ... 31(4 Suppl):S324-S328 Ware LB, Matthay MA: The acute respiratory distress syndrome N Engl J Med 2000, 342:1334-1349 The Acute Respiratory Distress Syndrome Network: Ventilation with lower tidal ... J, the Multicenter Oscillatory Ventilation for Acute Respiratory Distress Syndrome Trial (MOAT) Study Investigators: High-frequency oscillatory ventilation for acute respiratory distress syndrome...

Ngày tải lên: 12/08/2014, 23:22

... Figure respiratory analysis of independent transfusion risk factor for acute Multivariatedistress syndrome (ARDS) respiratory distress syndrome (ARDS) After covariates were adjusted for, the amount ... transfusion is an independent risk factor for the development of acute respiratory distress syndrome (ARDS) in the intensive care unit population 10 The association of allogeneic blood exposure ... predictors of the adult respiratory distress syndrome Am J Surg 1982, 144:124-130 Fowler AA, Hamman RF, Good JT, Benson KN, Baird M, Eberle DJ, Petty TL, Hyers TM: Adult respiratory distress syndrome: ...

Ngày tải lên: 13/08/2014, 03:21

... volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome The Acute Respiratory Distress Syndrome Network N Engl J Med 2000, 342:1301-1308 ... gas and tissue in acute respiratory distress syndrome III Consequences for the effects of positive end-expiratory pressure CT Scan ARDS Study Group Adult Respiratory Distress Syndrome Intensive ... taught us about the acute respiratory distress syndrome? Am J Respir Crit Care Med 2001, 164: 1701-1711 Papadakos PJ, Lachmann B: The open lung concept of mechanical ventilation: the role of recruitment...

Ngày tải lên: 13/08/2014, 10:20

... recognize the primary mechanism underlying the effects of shunt A low cardiac output or a high metabolic rate augments the venous content of carbon dioxide, and thereby the effect on shunt on PaCO2 The ... inspiration is another; dead space can also be reduced by selecting a mode of inspiration that lengthens the mean distribution time during which the alveolar tidal volume is present in the respiratory ... Vdphys is the physiological dead space, Vdaw is the airway dead space, and VdAVQ is the part of alveolar dead space that is caused by alterations in the ventilation/perfusion relationships other than...

Ngày tải lên: 13/08/2014, 10:20

... (Crs) during respiratory distress syn-endance of the respiratory system (Crs) during a decremental positive endexpiratory pressure (PEEP) trial after acute respiratory distress syndrome (ARDS) ... collected the data during the experiments BL and PG analysed the data and performed the statistical analysis VD participated in the design and the coordination of the study and helped to draft the ... compliance of the respiratory sysand static compliance of the respiratory system (Crs) conditions of the present study, but may not be warranted in the clinical setting It could be argued that the effects...

Ngày tải lên: 13/08/2014, 11:22

... [5] Several studies focused on the effects of IAH on other organ systems, especially the respiratory system [1,5] The World Society of the Abdominal Compartment Syndrome (WSACS) [6] has published ... ACS after PEEP 12 cmH2O In the literature (Table 2) there is some controversy about the effect of mechanical ventilation and the use of PEEP on IAP The heterogeneity of the observed differences ... between the different studies (Table 2) may be explained in part by the differences in the patient populations Sussman and colleagues [8] was the first to look at the effects of PEEP on IAP and in their...

Ngày tải lên: 13/08/2014, 21:21

... THƯƠNG TỔN PHỔI CẤP TÍNH (ACUTE LUNG INJURY : ALI) LÀ GÌ ? Các định nghĩa truyền thống ARDS không bao gồm bệnh nhân với cớ thương tổn phổi cấp tính mức độ nhẹ hay xảy sớm Theo đó, tiêu chuẩn sau ... (disseminated intravascular coagulopathy)  viêm tụy tạng  hội chứng nghẽn mạch mỡ (fat embolism syndrome)  bắt cầu tim-phổi (cardiopulmonary bypass) NHỮNG NGUYÊN NHÂN CHÍNH  Choáng tuần hoàn ... NHỮNG BỆNH NHÂN VỚI ARDS BỊ CHẾT ?  10% tử vong bệnh nhân bị ARDS suy hô hấp giảm oxy mô (hypoxic respiratory failure)  hầu hết tử vong xảy vòng 72 chấn thương khởi thủy  sau 72 tỷ lệ tử vong...

Ngày tải lên: 26/07/2014, 19:20

... (Figure 2) Therapy with amikacin, ceftazidime, G-CSF and voriconazole was started Within a few hours, her clinical condition deteriorated and the patient developed Acute Respiratory Distress Syndrome ... resistance on the return part of the circuit caused a massive thrombosis in the oxygenator The entire circuit and the cannula were immediately changed and ECMO restarted within hours Following the development ... and interpreting the patient’s data during the ICU admission and has been involved in drafting the manuscript for the part concerning the ICU admission He gave final approval of the version to...

Ngày tải lên: 11/08/2014, 17:21

... with the management of this case while in hospital and have equally contributed to the design, drafting and editing of the article submitted The authors also acknowledge the contribution of other ... Sulfasalazine) [6], chemotherapy, radiotherapy [7] and connective tissue disorders However the potential benefit of timely corticosteroid therapy in patients with BOOP may justify the added risk of ... with normal fibrinogen levels The aetiology of acute coronary syndrome in association with BOOP remains unclear Competing interests 10 11 12 13 The authors declare that they have no competing interests...

Ngày tải lên: 11/08/2014, 23:21

... et al Respiratory Research 2011, 12:32 http:/ /respiratory- research.com/content/12/1/32 the S-S bond near the surface of the epithelial cell membrane, KL-6 can diffuse into pulmonary epithelial ... Briefly, the probe was inserted into the channel and gently advanced While the outer sheath was set at the target in the subsegmental bronchus, the inner probe was advanced slowly into the peripheral ... abbreviations ALI: acute lung injury; ANOVA: analysis of variance; ARDS: acute respiratory distress syndrome; AUC: area under the curve; BALF: bronchoalveolar lavage Kondo et al Respiratory Research...

Ngày tải lên: 12/08/2014, 13:22

... MA: The Acute Respiratory Distress Syndrome New Engl J Med 2000, 342:1334-1349 Gattinoni L, Chiumello D, Cressoni M, Valenza F: Pulmonary computed tomography and adult respiratory distress syndrome ... characterize the system, namely the total mass in the system (Mtot = M1 + M2), the mean residence time of molecules entering the system from alveoli or lung tissue (MRT1, MRT2), defined as the sum of the ... regarding the site of degradation of surfactant The present results agree with the view that, in ARDS, only a fraction of the lung is accessible to exogenous surfactant In fact, the decrease of the...

Ngày tải lên: 12/08/2014, 15:20

... volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome The Acute Respiratory Distress Syndrome Network N Engl J Med 2000, 342:1301-1308 ... thirty-day mortality in the Acute Respiratory Distress Syndrome (ARDS) in an adult ICU Anaesth Intensive Care 2004, 32:317-329 Ware LB, Matthay MA: The acute respiratory distress syndrome N Engl J ... acquiring the data WS was involved in the design of the study and contributed to the writing of the manuscript with comments AG conceived the study, participated in the design and helped drafting the...

Ngày tải lên: 12/08/2014, 15:21

... Acknowledgements 18 The authors thank Dr Liliane Bodin, Dr Pierre Kalfon and Dr Pascale Poète for their contribution to the study; the nurses of the Surgical Intensive Care Unit and the technicians of the Department ... the use of innovative therapies in sepsis Crit Care Med 1992, 20:864-874 Bernard GR, Artigas A, Brigham KL: Report of the AmericanEuropean Consensus Conference on acute respiratory distress syndrome: ... (Pop), static respiratory compliance (Crs) calculated as the slope of the curve between 500-1000 ml, and quasi-static respiratory compliance (Cqs), obtained by dividing the VT by the corresponding...

Ngày tải lên: 12/08/2014, 18:20

... occurrence of the first particle and all the following particles The product of CO and MTT is the volume between the site of injection and the site of detection The DST can be derived from the extrapolated ... dilution curve The MTT is composed of the appearance time ATi, which is the time until the first indicator particle has arrived at the point of detection, and the mean time difference between the occurrence ... way that they were unable to trigger the ventilator When necessary, they were also paralysed with pancuronium The ventilator settings were unchanged during the experiments At the start of the study...

Ngày tải lên: 12/08/2014, 18:21