test a spy was called with a specific set of arguments

... amino acids offset) and probed with patient sera Each arginine containing peptide was synthesized as three variants, one with natural arginine (R), one with symmetrical dimethylarginine (sDMA) ... dimethylated arginine residues for epitopes assay Assay performance characteristics of the anti-SmD3 peptide (SMP) assay (a) Intra-assay and interassay variability, (b) linearity, and (c) receiver operating ... extensions of both polypeptides were synthesized with an offset of two amino acids (13 amino acid overlap) Each arginine-containing peptide was synthesized as three variants, one with natural arginine,...

Ngày tải lên: 09/08/2014, 06:22

... view of focus of attention a word is treated as having a static semantics However metaphor can make the semantic type of objects more flexible By using a verb that only applies to humans, as above, ... terms of a moving vehicle at the same time emphasizing the effort that it takes to leave (as in section 3.3) A party can be described, via "is -a" links of the abstraction hierarchy, as a human process ... level of abstraction, where the key role (termination) is specified, we can search for a candidate metaphorical domain that shares this ancestor There are several possible metaphorical domains that...

Ngày tải lên: 31/03/2014, 06:20

... Genetech, San Francisco, CA), anti-TNFa (Humira, Abbott, Abbott Park, IL), anti-IL-1b (clone AB-206-NA, Abcam, Cambridge, MA), anti-IL-6 (clone AB-201-NA, Abcam), anti-GM-CSF (clone BVD2), anti-TGFb ... 3:721-732 Matsusaka T, Fujikawa K, Nishio Y, Mukaida N, Matsushima K, Kishimoto T, Akira S: Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, ... MDSC samples (4-998 osteogenic sarcoma, DU 145 prostate carcinoma, CAKI-1 renal cell carcinoma, SKOV-3 ovarian carcinoma, and SW 608 and SW 732 colorectal adenocarcinoma cell lines), we analyzed...

Ngày tải lên: 18/06/2014, 19:20

... DMSO before irradiation on ice and sample preparation Alternatively, cells were incubated for repair prior to lysis Data analysis involved quantification of the fraction of total DNA mass in electrophoretically ... MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks Proc Natl Acad Sci USA 2008, 105:11200-11205 19 Ayoub N, Jeyasekharan AD, Bernal JA, Venkitaraman AR: HP1-β ... breaks repair only at low levels of DNA damage Cell Cycle 2006, 5:1116-1122 41 Nazarov IB, Smirnova AN, Krutilina RI, Svetlova MP, Solovjeva LV, Nikiforov AA, Oei SL, Zalenskaya IA, Yau PM, Bradbury...

Ngày tải lên: 09/08/2014, 09:20

... such that a ↓ a ' and a ≠ a ' ; (ii) for any a, b ∈ F and a ≠ b, we have a ↓ a ' and b ↓ b ' where a ', b ' ∈ F and a ' ≠ b ' In 28 Chapter Tile Set Formation other words, each patch placed at the ... patches are rotated and arranged, with a small amount of overlap, as a diamond shape block, to cut a Wang tile from its center along four diagonals of the patches such as the one shown 15 Chapter Previous ... part C of O to obtain an ω-tile We adapt Kwatra et al [KSET03] to derive C Very briefly, their work computes a cutting path for a given pair of patches I and O that overlap at some pixels as a...

Ngày tải lên: 05/10/2015, 19:02

... ngữ Nam Bộ Như vậy, không gian đ a lí tiếng miền Nam, phương ngữ miền Nam hay phương ngữ Nam tác giả xác đònh rộng Không gian đ a lí phương ngữ Nam Bộ xác đònh hẹp Ranh giới PNNB trùng với ranh ... (từ thû ấy/ đến nay), thû (từ thû ấy/ đến giờ) V a rút gọn v a đảo trật tự câu nghi vấn tính chất, đặc điểm: bao cao (cao bao nhiêu), bao dai (dài bao nhiêu), bao lớn (lớn bao nhiêu)… Rút gọn, ... Long An, Tiền Giang, An -18- Giang, Kiên Giang, Cà Mau, Sóc Trăng, Bạc Liêu, Đồng Tháp, Bến Tre, Hậu Giang, Vónh Long, Trà Vinh thành phố Cần Thơ Vò trí đ a lí Nam Bộ: ph a bắc tây - bắc giáp Cam-pu-chia,...

Ngày tải lên: 17/04/2013, 16:09

... a general set of data that consists of 53 A- mutants, with 28 of them having near wildtype stability (128) and the remainder being mutants with reduced stability (2953) This set of data was randomly ... mathematical models These statistical analyses were carried out using the statistica software package [77] Forward stepwise was xed as the strategy for variable selection in the case of LDA and LMR analysis ... fractional side-chain solvent accessibility, with changes in buried surface area, with average side-chain B-factors, and with the number of side-chain atoms or total atoms within A of the atoms...

Ngày tải lên: 29/03/2014, 09:20

... following additional data are available with the online version of this manuscript Additional data file provides supporting figures Additional data file provides supporting tables Additional data file ... analyzed Although using curated databases results in a more accurate set of conserved pairs, this analysis is limited to a small (and sometimes biased) set of genes In addition, the binary assignment ... response and circadian rhythm Materials and methods Assigning cyclic status to genes We applied a probabilistic graphical model to combine microarray expression data and sequence data for identification...

Ngày tải lên: 14/08/2014, 08:20

... (11) AA6 244 50 (15) AA9 252 50 (11) Population code AA10 APPAL Appaloosa W USA 84 29 AB Arab-Barb W Morocco 71 38 AR Arab W France 1267 50 ARD Ardennais D France 645 50 AUX Auxois D France 130 ... those groups according to the proportion of foreign genes that can be found from genealogical analysis: AA6 and AA9 are considered as pure AA, whereas AA5 and AA10 can have ancestors from another ... the gene pool of these sub-populations Within the AA breed, AA5 and AA6 populations appeared distinct from AA9 and AA10 populations and close to the PS breed This was in agreement with the studbook...

Ngày tải lên: 14/08/2014, 13:21

... or gain of total diversity when the breed is removed; Ci = contribution of the breed to optimise GDT Table 2: Corrected Table Three Breed code Nb of breeding animals in 2005 Males AA AR ARD AUX ... JL: Aggregate diversity: New approach combining within- and between-breed genetic diversity Livest Prod Sci 2005, 95:247-254 Caballero A, Toro MA: Analysis of genetic diversity for the management ... for disseminating the results of biomedical researc h in our lifetime." Sir Paul Nurse, Cancer Research UK Your research papers will be: available free of charge to the entire biomedical community...

Ngày tải lên: 14/08/2014, 13:21

... be maintained between the maternal and paternal genomes Remarkably, of the 190 genes that are associated with CNEs in humans and have orthologs in C elegans, 60 have orthologs that are also associated ... high-quality databases: DBD, a database of computationally predicted transcription factors through homology to known DNA-binding domains [29]; and wTF2.0, a compendium of computationally and manually ... intercals (CI) and p-values were calculated using the R statistical package [55] (according to a two-tailed test) The p value threshold at the 5% false discovery rate (FDR) cut-off was calculated according...

Ngày tải lên: 14/08/2014, 17:22

... Han CG, Ohtsubo E, Nakayama K, Murata T, Tanaka M, Tobe T, Iida T, Takami H, Honda T, Sasakawa C, Ogasawara N, Yasunaga T, Kuhara S, Shiba T, Hattori M, Shinagawa H: Complete genome sequence of ... O157 characterizations, culture, and DNA isolations, and analyzed 454 GS FLX and MALDI-TOF results Additional data files The following additional data are available with the online version of this ... O157:H7 strains in cattle Proc Natl Acad Sci USA 1999, 96:13288-13293 Ohnishi M, Terajima J, Kurokawa K, Nakayama K, Murata T, Tamura K, Ogura Y, Watanabe H, Hayashi T: Genomic diversity of enterohemorrhagic...

Ngày tải lên: 14/08/2014, 21:20

... Bering, Marburg, Germany; equivalent to about TU of PPD-S) was injected intradermally into the volar aspect of the forearm and transverse induration diameter was measured 72 hours later Individuals ... between the date of entry to Germany and the date of contact tracing was 535.4 ± 394 weeks, with a range from 39 to 1601 weeks The mean age of the contacts was 28.5 ± 10.5 years (range 14–53) and there ... analysis CL and MF participated in the design of the study and the data interpretation KM recruited patients, obtained medical data and assessed results All authors read and approved the final manuscript...

Ngày tải lên: 12/08/2014, 16:20

... incubated with various concentrations of IAA for days, and cell viability was determined by MTT assay IC50 was calculated as the concentration of drug which inhibited cell growth by 50% Data were ... the treated animals to measure the biochemistry markers including alanine transaminase (ALT), aspartate aminotransferase (AST), blood urea nitrogen (BUN) and creatine (Cr) using commercial kits ... determined *Statistical analyses were conducted with one-way ANOVA for all the parameters P values less than 0.05 were considered statistically significant Xu et al Journal of Translational Medicine...

Ngày tải lên: 18/06/2014, 19:20

... Dutta P, Bhattacharya SK, Krishnan T, Kobayashi N, Naik TN: Genetic variability of human rotavirus strains isolated from Eastern and Northern India J Med Virol 2004, 72:156-161 Rahman M, Sultana ... 2001:1747-1785 Martella V, Ciarlet M, Baselga R, Arista S, Elia G, Lorusso E, Banyai K, Terio V, Madio A, Ruggeri FM, Falcone E, Camero M, Decaro N, Buonavoglia C: Sequence analysis of the VP7 and VP4 ... nucleotide mutation at the 3' end of the primer binding site Arch Virol 1997, 142:1881-1887 Taniguchi K, Wakasugi F, Pongsuwanna Y, Urasawa T, Ukae S, Chiba S, Urasawa S: Identification of human and bovine...

Ngày tải lên: 20/06/2014, 01:20

... incubated with various concentrations of IAA for days, and cell viability was determined by MTT assay IC50 was calculated as the concentration of drug which inhibited cell growth by 50% Data were ... the treated animals to measure the biochemistry markers including alanine transaminase (ALT), aspartate aminotransferase (AST), blood urea nitrogen (BUN) and creatine (Cr) using commercial kits ... determined *Statistical analyses were conducted with one-way ANOVA for all the parameters P values less than 0.05 were considered statistically significant Xu et al Journal of Translational Medicine...

Ngày tải lên: 20/06/2014, 03:20

... F, Vieta E, Martínez-Arán A, Garcia-Garcia M, Reinares M, Torrent C, Goikolea JM, Banús S, Salamero M: Spanish version of a scale for the assessment of mania: validity and reliability of the ... Juan José Uriarte, and Fermín Mayoral for their contribution in the linguistic validation Author details Department of Psychiatry, Hospital Universitario de Salamanca, Salamanca, Spain 2Department ... distribution of data Reliability The internal consistency of the questionnaire was analysed using Cronbach’s a Test- retest reliability of the scores was also examined by computing the intraclass correlation...

Ngày tải lên: 09/08/2014, 01:21

... destruction in RA in a phasic manner In our study, the association of the 1G- 5A haplotype with radiographic damage was comparable with that of the SE In addition, our data indicate that this association ... investigator (RR) who was unaware of the results of the genetic analyses At the Rheumaklinik Ratingen, radiographs of both hands and feet are routinely obtained for all RA patients at disease onset and ... It evaluates 38 joints separately (all proximal interphalangeal and metacarpophalangeal joints, four sites in the wrists, interphalangeal joints of the great toes, and metatarsophalangeals to...

Ngày tải lên: 09/08/2014, 01:23

... three years back He had no previous or family history of depression He was first diagnosed with RA fourteen years back and was treated with sulfasalazine and diclofenac for six years He gradually ... this strain of mice, suggesting that serotonergic pathways play an important role in modulating inflammatory pain, compared with mechanistic pain Antidepressants have anti-inflammatory and analgesic ... started him on escitalopram, a serotonin -specific reuptake inhibitor, at 10 mg/day, and risperidone, an antipsychotic with a serotonin dopamine antagonist action at mg/day Risperidone was started,...

Ngày tải lên: 11/08/2014, 00:23