temporal graph based language for querying collections of patient histories

... effectiveness of medications for rheumatoid arthritis (RA) due to the lack of a validated algorithm for this outcome We created and tested a claims -based algorithm to serve as a proxy for the clinical ... objective was to derive and test a claims -based algorithm to serve as a proxy for the effectiveness of medications for RA patients Materials and methods Eligible patient population After Institutional ... claims data To test the performance of the effectiveness algorithm and to see whether it was similar for non-biologic RA treatments, we performed a separate analysis of RA patients enrolled in VARA...

Ngày tải lên: 25/10/2012, 10:45

... Q-value of the previous state and the performed action according to the reinforcement and the value of the next state The agent receives a constant negative reinforcement for each action it performs ... expected sum of future reinforcement In Q-learning, a look-up table of Q-values is stored in memory, one Q-value for each state–action pair The Q-value is the expected amount of reinforcement if, ... the minimum number of actions A sensed state consists of a discretized position and force measurement, as described below A value is stored in a look-up table for each pair of state and Fig Learning...

Ngày tải lên: 28/03/2014, 14:20

... correctness of the transfer process is Assured ing Generalizations in Unification -based Grammar Formalisms" Proceedings of the Fourth Conference of the European Chapter of the Association for Computational ... knowledge the first formalization and implementation of a type of rule and control regime intended for use in situations where it is desired to produce the effect of transforming one feature ... argument of aimer to the first argument of nager by means of a re-entrancy The set of rules given below together establish a transfer relation between (3) and (4): s Applications of the Formalism...

Ngày tải lên: 01/04/2014, 00:20

... model of disc degeneration, intradiscal implantation of cell-free PGA/HA nucleusimplant facilitates the formation of superior nucleus pulposus repair tissue and the reduction of the loss of disc ... Thus, minimal removal of bone and articular structures was achieved Nucleotomy was performed after scalpel inci- Page of (page number not for citation purposes) Journal of Orthopaedic Surgery ... http://www.josr-online.com/content/4/1/25 Figure Statistical analysis of ROM Statistical analysis of ROM Statistical analysis of ROM of intact disc specimen, after nucleotomy and after implantation of the PGA-HA nucleus-implant using...

Ngày tải lên: 20/06/2014, 04:20

... To visualize intracellular uptake of the f-HNT -based- ASODN complex, fluorescence FAM- Page of labeled ASODNs were used for the complex formation A TEM image of HeLa cells after incubation with ... photoluminescence [PL] spectra were used to observe the formation of f-HNT-ASODN complexes After adsorption of ASODNs, the surface zeta potential of the f-HNT -based complexes decreased to a less positive ... promise in a range of applications as a nanoscale container for the encapsulation of biologically active molecules (e.g., biocides, enzymes, and drugs), as a support for immobilization of catalyst molecules,...

Ngày tải lên: 20/06/2014, 23:20

... http://www.nanoscalereslett.com/content/6/1/461 Page of Modification and coupling of superparamagnetic nanoparticle Determine of cutoff value and validation of QDs and superparamagnetic nanoparticle -based hybridization 3-Aminopropyl-trimethoxysilane ... assay on the basis of the cutoff value Detection of HPV-16 with QDs and superparamagnetic nanoparticle -based hybridization The rationale of QDs and superparamagnetic nanoparticle -based hybridization ... Approximately 50 mg of APTMS-modified Fe3O4 nanoparticles was added into 10 mL of 0.05 mg/mL of EDAC and sonicated for 25 at 4°C After being separated with a NdFeB magnet, 50 nmol of streptavidin...

Ngày tải lên: 21/06/2014, 01:20

... Q-value of the previous state and the performed action according to the reinforcement and the value of the next state The agent receives a constant negative reinforcement for each action it performs ... expected sum of future reinforcement In Q-learning, a look-up table of Q-values is stored in memory, one Q-value for each state–action pair The Q-value is the expected amount of reinforcement if, ... the minimum number of actions A sensed state consists of a discretized position and force measurement, as described below A value is stored in a look-up table for each pair of state and Fig Learning...

Ngày tải lên: 27/06/2014, 18:20

... nonhealth professionals, and, to a more limited extent, health professionals The distribution of the responsibilities for LTCM between groups of involved actors outside of the immediacy of the health ... The advantages of using a broad definition of networks is that it offers a means to explore the functions and limitations of different types of support and affinities between types of illness-related ... well-being for themselves and for others (see Figure patient- focused outcomes) 2) Illness management and types of work The scope of the potential involvement of different providers of illness management...

Ngày tải lên: 10/08/2014, 10:23

... sample Interpretation of Cut off value (RLU of specimen/mean RLU of PC) Cut-off ratio of to 0.99 is negative for HR HPV; Cutoff ratio greater than 1.0 positive for HR HPV The cut off ratio at 1.0 ... intensity of HPV infection This ratio of any specimen represents empirically a relative measure of the viral load in it Cut off value (RLU of specimen/ mean RLU of PC) was 1.0 pg/ml of sample ... of HPV viral load Ratio of relative light unit (RLU) of the sample/mean of RLU of three positive controls (PC) were taken as an estimate of approximate viral load which relates to the index of...

Ngày tải lên: 12/08/2014, 01:22

... key differences and allow for a comparison of the effect of a system structure on outcome Patient variables Patient variables should describe the patients' conditions before the intervention, specifically ... relating to patient safety and the reduction of adverse incidents We therefore think that such a template needs to be based on a consensus process supported by a geographically dispersed group of experts ... elements of the Theoretical Model of Factors in Patient Outcome published by the International Liaison Committee on Resuscitation, the so-called Utstein formula of survival [18] It has therefore...

Ngày tải lên: 13/08/2014, 23:21

... process for developing theory- and evidence -based intervention programs [13] and consists of six different steps: 1) needs assessment, 2) formulation of change objectives, 3) selection of theory -based ... areas) and negotiate for the improvement of neighbourhood safety Module 1: Establishment of the community platform Module 3: Short and a long term perspective for the prevention of childhood obesity ... 10 of 15 Table Examples of possible actions that could be undertaken by the stakeholders of the community platform (module 3) MODULE 3: SHORT AND A LONG TERM PERSPECTIVE FOR THE PREVENTION OF...

Ngày tải lên: 14/08/2014, 08:20

... and population 2, respectively [10] The lnRH test is based on the calculation of the logarithm of the ratio of H for each locus for a pair of populations as follows ⎛ ⎜ ⎜ − H pop1 ln RH = ln ⎝ ... Results Page of 14 also shows matrices of LD significance levels for all possible locus combinations of the loci on BTA1 or BTA20 in their chromosomal order Of the 120 pairwise comparisons of the 16 ... tests consider lnRθ of several linked loci for the inference of selection While the single-locus lnRθ-test is largely independent of the demographical past, the additional power of linked loci is...

Ngày tải lên: 14/08/2014, 13:21

... targets OxyR Cofactor synthesis RNA modification ATPases Heat shock response Figure Expression profiles of top-scoring classes for drug treatments Expression profiles of top-scoring classes for drug ... clustering methods performed poorly, with a false positive and false negative rate of about 50% The SA performed consistently well in identifying a subset of profiles (three out of seven profiles tested), ... eigenvector of the expression profile matrix for that class Analysis of simulated class data A simulated class dataset was generated by randomizing arrays in the expression profiles of SOS genes; 70% of...

Ngày tải lên: 14/08/2014, 16:21

... release profile of Dex from the nanofibers was investigated 3) The efficacy of the Dex-loaded PLLA nanofibers in the osteogenic differentiation of MSCs was evaluated 1) PLLA/Col nanofibers were ... funding and support for my Ph.D study at National University of Singapore I also would like to thank to my TAC members, Prof Teoh Swee Hin and A/Prof Li Jun, for their efforts in helping me complete ... acid nanofibers for bone graft materials Proceedings of International Conference for Micro & Nanotechnologies for Biosciences, 16 18/11/2009, Switzerland Poster presentation iv Table of Contents...

Ngày tải lên: 09/09/2015, 10:07

... nanomedicine for multimodality treatment of cancer? 38 2.4.3 Examples of nanomedicine for multimodality treatment of cancer 41 2.5 Approaches of nanomedicine for multimodality treatment of cancer ... The limitation of this method is that the light is hard to pass through more than one-third of an inch of tissue Therefore, PDT is often less effective for large 13 tumors It is often used to ... dacarbazine for treatment of patients with metastatic melanoma L19-IL2 was composed of an antibody fragment specific to the EDB domain of fibronectin and of human interleukin-2 Among 29 patients,...

Ngày tải lên: 10/09/2015, 09:24

... other sources of information that may be useful for function prediction As these sources of information can differ substantially in nature and representation, I propose a graph- based framework ... them for protein function prediction Each source of information is transformed into an undirected weighted graph A unified weighting scheme is proposed to assign weights to the edges of these graphs ... for function prediction np is the no of known functions of protein p; mp,β is the no of functions predicted for protein p at threshold β; and kp,β is the no of functions predicted correctly for...

Ngày tải lên: 12/09/2015, 08:18

... CORRELATION -BASED METHOD FOR DIRECTION FINDING OF MULTIPATH SIGNALS IN FREQUENCY HOPPING SYSTEMS PENG NINGKUN (M Eng, Huazhong University of Science and Technology) A THESIS SUBMITTED FOR THE DEGREE OF ... Convergence figures of FHC method for Stationary Case ………………57 4.5 Convergence figures of FHC method for Slow Moving Case …………62 4.6 Convergence behavior of stationary case for FHML method ………………… ... 4.7 Convergence behavior of slow moving case for FHML method ……………… 69 4.8 Variances of converged values of θ vs SNR…………………………………… 70 v List of Tables 4.1 An example of hop sequence…………… ………………………………………51...

Ngày tải lên: 15/09/2015, 22:51

... terms of some preconceived categories of emotions This technique is primarily intended for recording of emotions in infants and therefore is based on eight different categories of emotions often ... 134 6.6b Confusion matrix for second level of classification of Category A 134 6.6c Confusion matrix for second level of classification of Category C 134 6.7 Results for Cloud basis function network ... regions (a) for primary dataset and (b) for Half-face dataset 149 7.1 A summary of overall performance of different types of classification systems using test image database 163 xiv List of Tables...

Ngày tải lên: 16/09/2015, 17:11

... advantages of the transition -based strategy, the integrated algorithm we are looking for has to be transition -based at the top level The advantages of the graph- based approach – a more globally informed ... Nivre, 2010) o ı Since we use the scoring model of a graphbased parser, we briefly review releated work on graph- based parsing The most well known graph- based parser is the MST (maximum spanning tree) ... applies in this very type of situation: whenever information is added in the transition -based parsing process, the scores of all the histories stored in the beam are recalculated based on a scoring...

Ngày tải lên: 17/03/2014, 22:20

... dependency language model by extending the model of McDonald et al (2005) 3.1 Graph- based parsing model The graph- based parsing model aims to search for the maximum spanning tree (MST) in a graph ... the set of all the subgraphs of Gx that are valid dependency trees (McDonald and Nivre, 2007) for sentence x The formulation defines the score of a dependency tree y ∈ T (Gx ) to be the sum of the ... TYPE refers to one of the types:PL or PR , h pos refers to the part -of- speech tag of xh , h word refers to the lexical form of xh , ch pos refers to the part-ofspeech tag of xch , and ch word...

Ngày tải lên: 23/03/2014, 14:20