... Radiolabeled somatostatin receptor antagonists are preferable to agonists for in vivo peptide receptor targeting of tumors Proc Natl Acad Sci USA 103, 16436–16441 Storch D, Behe M, Walter MA, ... Roosterman et al directs SST-14 to lysosomal degradation This transient interaction of the receptor with arrestins is indicative of a class A receptor, and our data are in line with data in [16] and ... Spaziante R, Saveanu A, Jaquet P, Culler MD, Bianchi F, Rebora A et al (2007) Rapid pituitary tumor shrinkage with dissociation between antiproliferative and antisecretory effects of a long-acting...
Ngày tải lên: 16/03/2014, 06:20
... age of transition from juvenile to mature wood in a study of radiata pine The age of transition from juvenile to mature wood in radiata pine can be estimated only with reference to a particular ... volume) for each ring from pith to bark The first and last annual rings of each sample were rejected because they were too narrow for densitometry analysis For each annual ring, earlywood and latewood ... profile from pith -to- bark of latewood Therefore, transition age was estimated for latewood density only 2.5 Genetic analyses Single-site analyses of variance components for diallel data were carried...
Ngày tải lên: 07/08/2014, 16:20
practical markers of the transition from aerobic to anaerobic metabolism during exercise
... commonly operationalized as a threshold in blood lactate accumulation or gas exchange, may be a more appropriate point of reference compared to general percentages of maximal capacity (e.g., ... that accompany the aerobic –anaerobic transition are related to perceptions of exertion Furthermore, the lactate and ventilatory (gas exchange) thresholds have been shown to correspond to stable ... afferents from baroreceptors, chemoreceptors, mechanoreceptors, and interoceptors in the viscera and muscles, reach areas of the brain linked to affective responses [19] Therefore, it was hypothesized...
Ngày tải lên: 12/06/2014, 11:18
Báo cáo y học: " Avoiding the ‘twilight zone’: Recommendations for the transition of services from adolescence to adulthood for young people with ADHD" pot
... familial ADHD may further challenge families who, faced with unclear pathways for transition to adult care, have to navigate through a quagmire of healthcare bureaucracy to find appropriate adult ... simple, and clear transition pathway that, regardless of whether the young person comes from a paediatric or CAMHS team, provides age-appropriate assessment, triage and transition as required to adult/GP ... SY, DC and CM made revisions and edits to subsequent drafts All authors read and approved the final manuscript Authors’ information More information about ADHD, educational forums and training...
Ngày tải lên: 11/08/2014, 16:20
báo cáo khoa học: " Cold- and light-induced changes in the transcriptome of wheat leading to phase transition from vegetative to reproductive growth" pot
... 3, and weeks; b) a comBar diagram of TaVRN1 transcript abundance: a) a comparison of array data of the three varieties at 3, and weeks; b) a comparison of qRT-PCR data of vernalised Solstice and ... varieties4at of and data (normalised intensity) of the three comparison of Ent-kaurene Bar diagram3, 5array9 weeksoxidase transcript abundance: a Bar diagram of Ent-kaurene oxidase transcript abundance: ... Figure parison of qRT-PCR data of vernalised Solstice a comparison of array data at and 12 weeks Bar diagram of TaVRN1 transcript abundance: a) and non-vernalised controls of the three varieties at...
Ngày tải lên: 12/08/2014, 03:20
Tài liệu Báo cáo khoa học: Crystal structure of importin-a bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4 ppt
... cargo The average atomic B factors for importin -a in the structure are ˚ ˚ 32.1 A2 for main-chain atoms, 35.7 A2 for side-chain ˚ overall (3244 atoms) For the pepatoms and 33.8 A tide, B factors ... normalized B factor, Bi is the B factor of atom i, lj is the mean B factor (excluding water molecules and peptide atoms) and rj is the standard deviation of B factors The normalized B factors have a zero ... factor-2 pathway is normally used for the nuclear import of RanGDP [28], but nuclear transport factor-2 can also interact with cargo complexes [29] The nuclear transport of CLIC4 may therefore...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu The King''''s Post Being a volume of historical facts relating to the Posts, Mail Coaches, Coach Roads, and Railway Mail Services of and connected with the Ancient City of Bristol from 1580 to the present time pdf
... but, taking into account that the annual salary was £200 for expenses 'incident' to the office, the remaining £300 was not more than adequate payment for the constant and laborious duties attached ... lived Ralph Allen, 1727-1764," Lord Londonderry said that there was probably not one of the great men who had been associated with Bath who was more of a benefactor to his town, as well as to the ... later, postmaster of Bath, to a position of great affluence, and of friendship with many of the great men of his time Among those friends was Lord Chatham It was twenty years after Allen's death...
Ngày tải lên: 17/02/2014, 02:20
Tài liệu Báo cáo khoa học: Reversible tetramerization of human TK1 to the high catalytic efficient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration ppt
... nucleotide or phosphate compound for h at °C, and stored for at least weeks at )80 °C before use for kinetic and molecular mass analyses The activity at saturating conditions was similar before and after ... molecular mass markers were purchased from Sigma-Aldrich (Copenhagen, Denmark) Materials for cloning, PCR, DNA sequencing and assays were standard commercially available products Enzyme preparation ... light of these effects, the complex regulatory and structural properties of hTK1 may be important for maintaining a balanced supply of the DNA precursor This underlines the importance of elucidating...
Ngày tải lên: 18/02/2014, 12:20
Tài liệu Báo cáo khoa học: Temperature and phosphate effects on allosteric phenomena of phosphofructokinase from a hibernating ground squirrel (Spermophilus lateralis) pptx
... hibernator PFK allostery J A MacDonald and K B Storey Fig Effects of pH and inorganic phosphate concentration on the activity of S lateralis phosphofructokinase at °C Activities are expressed relative ... probably due to temperature alone Sensitivity to adenylates (ATP inhibition, AMP and ADP activation) was reduced when the enzyme was assayed at °C, a temperature characteristic of hibernation, as ... with the addition of allosteric activators (F1,6P2, F2,6P2, AMP, inorganic phosphate, or NH4+) or a rise in pH value to near [17–19] As would be predicted for an activator, the addition of 10 mm...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: Quantitative estimation of channeling from early glycolytic intermediates to CO2 in intact Escherichia coli pdf
... electroporated to facilitate entry of 3H-labeled aminoacyl-tRNA and 14C-labeled free amino acids The quantities of [14C]aminoacyl-tRNA (made in the pathway from 14C-labeled amino acids), [3H]aminoacyl-tRNA, ... these data allowed us to calculate the fraction of the total flux to CO2 that was channeled We used an E coli 3261 Quantitation of channeling in intact E coli G Shearer et al mutant that was engineered ... result in data that could be used to calculate the quantitative importance of channeling in a specific pathway They used Chinese hamster ovary cells in studies of channeling of aminoacyl-tRNA for protein...
Ngày tải lên: 19/02/2014, 18:20
Tài liệu Chronicle of London from 1089 to 1483 pdf
... Clyfford at Hawardyn, and sclowe and tok manye of his mene, and beseged the castell of Flynt and Rothelan, and tok the toun of Claupautern[13] and caste adowe the walles [Footnote 13: "Lambatre vanc" ... parlement was at Northt'; and there was Kirkeby drawe and hanged for the deth of a marchaunt of Jene, and a whit frere was punysshed for wordes that they hadde seyde be the duke of Lancastre And ... kyng and his barons, and the bysshop of Hereford was taken and lad into Walys into a castell Also in that discord Elianore the quene was foule repreved and almost sclayn upon London bregge: and after...
Ngày tải lên: 20/02/2014, 08:20
Tài liệu Worst To First Or A ‘Shock’ing Tale of Women’s Basketball in Motown pdf
... included Natasha Anderson, Laura Baker, Leslie Brown, Laurie Byrd, Claudia Maria das Neves, Latasha Dorsey, and Oksana Zakaluzhnaya On May 7, the first few cuts were made, and sadly one of the players ... Ndiaye-Diatta once again was in top form, as were Wendy Palmer and Edwina Brown Despite all that, the Storm was able to prevail by a final of 74-69 It was on to Phoenix, and one more tough break for the ... was also a member of both the 1996 Olympic team and the 1998 world championship squad From Bulgaria via Florida came Gergana Branzova, all six foot four of her She played for the national team...
Ngày tải lên: 21/02/2014, 17:20
Tài liệu The History of England from the First Invasion by the Romans to the Accession of King George the Fifth Volume 8 docx
... to aspire to office, and commands and honours, to form cabals against their competitors, and to distract the attention of the monarch by their importunity or their complaints They contained among ... was taken by the parliamentary forces Hamilton's brother Lanark was also forbidden to appear at court; and, having received advice that he would be sent to the castle of Ludlow, made his escape ... quarter the most remote from danger; but it was an army better adapted to the purpose of predatory invasion than of permanent warfare Occasionally it swelled to the amount of several thousands:...
Ngày tải lên: 22/02/2014, 04:20
Tài liệu Báo cáo Y học: Binding of gelsolin domain 2 to actin An actin interface distinct from that of gelsolin domain 1 and from ADF/cofilin pptx
... 1381–1385 Bamburg, J.R (1999) Proteins of the ADF/cofiln family: Essential regulators of actin dynamics Ann Rev Cell Dev Biol 15, 185–230 Hatanaka, H., Ogura, K., Moriyama, M., Ichikawa, S., Yahara, I ... hydrolysate used alone Each assay was conducted in triplicate and the mean value plotted after subtraction of nonspecific absorption The binding parameters (apparent dissociation constant Kd and the ... using alkaline phosphatase-labelled anti-IgG antibodies (1 : 1000) or alkaline phosphatase-labelled streptavidin (1 : 1000) Control assays were carried out in wells saturated with gelatin and gelatin...
Ngày tải lên: 22/02/2014, 07:20
Tài liệu Báo cáo Y học: Trehalose-based oligosaccharides isolated from the cytoplasm of Mycobacterium smegmatis Relation to trehalose-based oligosaccharides attached to lipid docx
... acetate, 2,3, 4-trimethylgalactitol acetate and 2,3,4,6-tetramethylgalactitol acetate As the amount of CO6 available for characterization was too low for NMR analysis, additional characterization ... stachyose); lane 2, a- galactosidase treatment of CO5; lane 3, a- galactosidase treatment of CO6; lane 4, a- glucosidase digestion of CO5; lane 5, a- glucosidase digestion of CO6 After chromatography and ... homologs of trehalose may be analogous to synthesis of raffinose and stachyose from sucrose [9] In that case the donor of galactose to sucrose to form raffinose is galactinol, i.e galactosyl myoinositol,...
Ngày tải lên: 22/02/2014, 07:20
Tài liệu Transfer of Skills from Spanish to English: A Study of Young Learners doc
... year of data, we will examine the data with a different analytical approach—structural equation modeling The advantage of this approach is that it will enable us to define our variables—for example, ... phonology test and a phonemic segmentation task (phonological awareness); a letter, word, and pseudoword naming task (word reading); and tests of cognate awareness and morphological awareness (word knowledge) ... collecting data on home language use and family reading practices from parent questionnaires, and data on schooling history from school records Using these data as one of the variables in our analysis...
Ngày tải lên: 24/02/2014, 18:20
TEXTBOOK OF Hepatology From Basic Science to Clinical Practice doc
... James M Crawford MD PhD Lluís Donoso MD Multiorgan Transplant Program Toronto General Hospital Toronto, ON, Canada Professor and Chair Department of Pathology, Immunology and Laboratory Medicine ... presentation It has particularly to be remembered that the anatomical appearance of the liver, as for every organ, is subject to wide variability Internal anatomy Although the external aspect of ... TS, Sakagami S, Ito H (1989) Intrahepatic territory of the accessory hepatic artery in the human Acta Anat 136, 34 –37 19 Skandalakis JE, Skandalakis LJ, Skandalakis PN et al (2004) Hepatic surgical...
Ngày tải lên: 06/03/2014, 09:21
The Cavalier Songs and Ballads of England from 1642 to 1684 Edited doc
... James In A Summer's Day INTRODUCTION The Cavalier Ballads of England, like the Jacobite Ballads of England and Scotland at a later period, are mines of wealth for the student of the history and ... loyalty Valued at a higher rate He that bears a sword Or a word against the throne, And does profanely prate To abuse the state, Hath no kindness for his own What tho' painted plumes and prayers ... rout again; Fly like light about, Face to the right-about, Charge them home again When they come on again; SING TANTARA RARA, BOYS, TANTARA RARA, BOYS, This is the life of an Old Cavalier Ballad:...
Ngày tải lên: 06/03/2014, 13:20
An Illustrated History of Ireland from AD 400 to 1800 potx
... Leabhar buidhe Mhic Murchadha, or Yellow Book of Mac Murrach; the Leabhar Arda Macha, or Book of Armagh (quoted by Keating); the Leabhar ruadh Mhic Aedhagain, or Red Book of Mac Aegan; the Leabhar ... materials for early Roman history, and those for the early history of that portion of the Celtic race which colonized Ireland We have no trace of any historical account of Roman history by a ... of each brave province, From a cantred up to a great chieftaincy From this valuable extract we obtain a clear idea of the importance and the subject of the famous Saltair, and a not less clear...
Ngày tải lên: 08/03/2014, 12:20