... for {S n (B)}∞ in the stronger topology space is easily obtained (see the proof of Theorem 2.1) n=1 Furthermore, we obtain the existence of an exponential attractor in the stronger topology space ... technique tool, i.e., Theorem 2.1, which will guarantee the existence of an exponential attractor in a stronger topology space In Section 3, we prove the existence of exponential attractors in L2 (Ω ) ... our main theorem which describes our new technique to construct an exponential attractor in a stronger topology space Theorem 2.1 Assume that p q > and Ω ⊂ Rn is bounded Let {S n }∞ n=1 be a...
Ngày tải lên: 29/10/2015, 14:20
Synthesis and structure investigation of stabilized aromatic oligoamides and their interaction with g quadruplex structures 1
... areas have been broadened For example, several folded α-peptides have been revealed to display strong antibacterial and antimicrobial activity.4,5 Recently, there has been increasing interest...
Ngày tải lên: 10/09/2015, 15:49
Synthesis and structure investigation of stabilized aromatic oligoamides and their interaction with g quadruplex structures 2
... majority of these NOE intensities between interior methoxy protons and amide 28 protons are much stronger than the weak NOE contacts between amide protons and the neighboring aromatic protons ortho ... ortho to the amide bonds For example, the NOE contact between protons and in pentamer 5c is much stronger than that between protons and in the same molecule This implies that the methoxy protons ... causing the plane involving the weaker H-bonds to deviate significantly from the plane involving stronger H-bonds at the nitro end A combination of π-π interactions, the presence of amide proton...
Ngày tải lên: 10/09/2015, 15:49
Synthesis and structure investigation of stabilized aromatic oligoamides and their interaction with g quadruplex structures 3
... The amide protons resonating at low fields (9.87-10.36 ppm) are in line with the existence of strong intramolecular H-bonds in 5b.2c,2d Since the inter-atomic distances between amide and methoxy ... to a typically observed helical pitch of ~ 3.4 Å for aromatic foldamers 95 Correspondingly, a strong NOE cross peak between the end ester methyl protons and the aromatic proton 24, serving as ... hexamer, the amide protons resonate at low fields (9.71-10.15 ppm), suggesting the existence of strong intramolecular H-bonds in Furthermore, the crescent and helical structure in was probed by...
Ngày tải lên: 10/09/2015, 15:49
Synthesis and structure investigation of stabilized aromatic oligoamides and their interaction with g quadruplex structures 4
... resonating at the very low field (10.88-10.89 ppm) are a diagnostic indicator of the presence of strong H-bonding interactions, leading to the rigidification of the amide linkages and a crescent...
Ngày tải lên: 10/09/2015, 15:49
Synthesis and structure investigation of stabilized aromatic oligoamides and their interaction with g quadruplex structures 5
... typical anti-parallel structure In contrast, the CD spectrum of ODN-1 in 100 mM K+ ion showed a stronger positive band at 290nm, with a weak negative peak near 255 and 235 nm (Figure 5.4a, black), ... conformations, while cyclic pentamers folded into an almost planar disc arrangement reinforced by strong intramolecular H-bonding forces The PCR stop assay implies that good planarity found in macrocycles...
Ngày tải lên: 10/09/2015, 15:49
Synthesis and structure investigation of stabilized aromatic oligoamides and their interaction with g quadruplex structures 6
... Table 6.1 lists all the DNA-modified AuNPs AuNPs heavily loaded with linear DNA strands possess strong interparticle electrostatic repulsion, which protects the AuNPs from aggregation in the salt ... could be possibly explained by the interaction between complementary DNAs in Au-T3/Au-T4 being stronger than that between thrombin and its aptamer TBA2 6.2.4 Sensitivity of Double Aptamer Biosensors ... in the duplex approach shows that the interaction of TBA with its complementary DNA strand is stronger than that between TBA and thrombin If this is also applicable to TBA2, AuNPs should disaggregate...
Ngày tải lên: 10/09/2015, 15:49
Synthesis and structure investigation of stabilized aromatic oligoamides and their interaction with g quadruplex structures 7
... protein and its aptamer such as TBA could be specifically disrupted by small molecule capable of strong binding toward TBA Thus, the developed AuNPs screening assay allows the efficient and specific...
Ngày tải lên: 10/09/2015, 15:49
.OVER THE TOP WITH THE THIRD AUSTRALIAN DIVISIONBY G.P. CUTTRISSWITH INTRODUCTION BY ppt
... plodding along),Send all ye can of such great souls to help us,Make us and keep us triumphant and strong G.P CUTTRISS and J.W HOOD FOOTNOTES: [1] Ploegsteert 'OVER THE TOP.' From the time of our...
Ngày tải lên: 06/03/2014, 03:21
Báo cáo khoa học: Interaction of synthetic peptides corresponding to hepatitis G virus (HGV/GBV-C) E2 structural protein with phospholipid vesicles doc
... weak interaction between this sequence and negatively charged SUVs In contrast, W-E2(279–298) strongly interacted with PtdCho ⁄ PtdSer (65 ⁄ 35) vesicles, as the blue shift of Trp was 11 nm To...
Ngày tải lên: 07/03/2014, 17:20
Báo cáo khoa học: Interaction of G-rich GT oligonucleotides with nuclearassociated eEF1A is correlated with their antiproliferative effect in haematopoietic human cancer cell lines potx
... addition of increasing amounts of protein (lanes 2–4) In contrast, labelled GT was found to bind with stronger affinity to eEF1A in a manner directly proportional to protein quantities (lanes 5–7) The ... using GRO26A (lane 5) Discussion A series of guanosine-rich phosphodiester oligodeoxynucleotides strongly inhibits proliferation in a number of human tumour cell lines and the presence of FEBS Journal ... from the plasma membrane, and their biological activity correlates with binding to these proteins Strong evidence showed that one of these proteins is nucleolin, a multifunctional phosphoprotein...
Ngày tải lên: 16/03/2014, 13:20
Báo cáo khoa học: The study of G-protein coupled receptor oligomerization with computational modeling and bioinformatics doc
... tools makes their success in predicting likely dimerization ⁄ oligomerization interfaces of GPCRs strongly dependent on the number of sequences available for each family or subfamily of these proteins ... Computational Chem 19, 319–333 59 Palczewski K, Kumasaka T, Hori T, Behnke CA, Motoshima H, Fox BA, LeTrong I, Teller DC, Okada T, Stenkamp RE et al (2000) Crystal structure of rhodopsin: a G protein-coupled...
Ngày tải lên: 16/03/2014, 22:20
Nonlinear physics with mathematica for scientists and engineers r ennis, g mcguire
Ngày tải lên: 17/03/2014, 14:31
Báo cáo khoa học: Identification of three proteins that associate in vitro with the Leishmania (Leishmania) amazonensis G-rich telomeric strand pdf
Ngày tải lên: 23/03/2014, 13:20