systems for controlled release of bioactive agents
Evaluation of advanced paclitaxel drug delivery implants for controlled release post surgical treatment against glioblastoma multiforme in the brain
Ngày tải lên :
05/10/2015, 21:33
... reported release profile suggested a form of delayed release where little or no drug was released for 30 days before a gradual controlled release was observable thereafter The objective of this ... control of the rate of polymer degradation can be achieved thereby changing rate of release of the drug Our study focuses on developing controlled releases implants in the form of discs for Paclitaxel ... step-by-step approach in the analysis of the use of foams for controlled release of Paclitaxel as implants within the brain for the post-surgical treatment of glioblastoma multiforme through combining cell...
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Báo cáo hóa học: " Probabilistic polynomial dynamical systems for reverse engineering of gene regulatory networks" docx
Ngày tải lên :
21/06/2014, 03:20
... and consists of two Gröbner cones of equal sizes (volumes) Each one of the two coordinate polynomials for f1, for instance, corresponds to of the total size of the Gröbner fan Therefore, under ... expense of having to compute the entire Gröbner fan of the ideal of points For small networks the computation of the fan is feasible but as the number of network nodes increases, the complexity of ... coefficient of in(g) in g is for each g ∈ G 2.3 Ideals of points Given a set of points, it is often necessary to find all the polynomials that vanish on it Such a set of polynomials forms an ideal...
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báo cáo hóa học:" Research Article Automatic Speech Recognition Systems for the Evaluation of Voice and Speech Disorders in Head and Neck Cancer" pdf
Ngày tải lên :
21/06/2014, 20:20
... of “very good normal speech.” For the four raters of the OC patients there was no need to alter the Likert scale For both databases the mean score of all perceptual evaluations was computed for ... scores of the raters and the WR even though both scales differ in their order of magnitude Comparisons of the mean values were performed using Student’s T-test The test for normal distribution of ... computed for each of the raters using the respective other raters as reference, that is, the mean of the four other raters for the LE group and the three other raters for the OC group For the...
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Báo cáo hóa học: " Strategies for Controlled Placement of Nanoscale Building Blocks" doc
Ngày tải lên :
22/06/2014, 18:20
... American Institute of Physics.) forming ordered 2D QD arrays can be utilized to form 3D QD crystals through stacking of 2D QD arrays Formation of 3D QD crystals was demonstrated for InAs/GaAs QDs ... demonstrated for an array of 100 electrode pairs They attributed this controlled placement of single MWNTs to a combined result of a dielectrophoretic force, an electrophoretic force, and a mechanical ... sign of surface charges, etc.) have also been assembled using capillary force driven placement Xia and co-workers demonstrated the formation of asymmetric dimers composed of two different kinds of...
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Báo cáo khoa học: "Techniques for controlled synthesis of the Douglas-fir - Laccaria laccata ectomycorrhizal symbiosis" docx
Ngày tải lên :
08/08/2014, 23:22
... Sci For 35, 1-18 Shemakanova NM (1962) Mycotrophy of woody plants In: Academy of Science of the USSR (Transl Israel Program for Scientific Transl, Jerusalem, 1967) Available from US Dept of Commerce, ... propagules (determi- nation of colony forming units by spreading ml of suspension on a 6-cm Petri dish with nutrient agar) The viability of the suspension does not decrease before weeks at °C Vermiculite-peat ... are supplied by (La Ménitré, 49250 Beaufort-enVallée, France) All the aseptic experimental systems presented here are designed for studying the dynamics of symbiosis establishment between the...
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báo cáo khoa học: "Enzymatic- and temperature-sensitive controlled release of ultrasmall superparamagnetic iron oxides (USPIOs)" pdf
Ngày tải lên :
11/08/2014, 00:23
... irreversible return of the R2 values to the baseline levels prior to the formation of the clusters The rate of de-clustering is expected to be controlled by the relative concentrations of the enzyme ... USPIO clusters for the detection of matrix metalloproteinase activity in tumors Methods General Figure Controlled release of USPIO micelles by environmental triggers (A) Self-assembly of EcoRV-sensitive ... excess of DBU, without significant risk of the DBU leading to side products during the polymerization process (Figure 1) Injection of a stoichiometric amount of the propylene sulfide monomer forms...
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Báo cáo khoa hoc:" Correction: Enzymatic- and temperature-sensitive controlled release of ultrasmall superparamagnetic iron oxides (USPIOs)" potx
Ngày tải lên :
11/08/2014, 08:20
... Giorgio, T D (2011) Enzymatic- and temperature-sensitive controlled release of ultrasmall superparamagnetic iron oxides (USPIOs) Journal of Nanobiotechnology 9, ... *Corresponding author Correction: After publication of this work [1], we found an error in the figure legend for Figure two In Figure twoA, GPC chromatograms of the synthesized co-polymers were shown, ... Correction: Enzymatic- and temperature-sensitive controlled release of ultrasmall superparamagnetic iron oxides (USPIOs) Shann S Yu1,2, Randy L Scherer2,3,...
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Controlled release of anticancer drugs, proteins and liposomes by polymeric microspheres
Ngày tải lên :
17/09/2015, 17:20
... efficiency of liposomes in LIMs 41 In vitro release 41 2.18.1 In vitro release of paclitaxel from microspheres 41 2.18.2 In vitro release of HSA from microspheres 42 2.18.3 In vitro release of liposomes ... CONTROLLED RELEASE OF ANTICANCER DRUGS, PROTEINS AND LIPOSOMES BY POLYMERIC MICROSPHERES BY RUAN, GANG (M Eng.) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHYLOSOPHY DEPARTMENT OF CHEMICAL ... analysis of HSA Figure 4.11 Effect of polymers on encapsulation efficiency of HSA in microspheres Figure 4.12 Effect of polymers on in vitro release of HSA from microspheres Figure 4.13 Effect of additives...
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Robotic systems for inspection surveillance of civil structures
Ngày tải lên :
24/02/2016, 10:27
... Accepted by the Faculty of the Graduate College, The University of Vermont, in partial fulfillment of the requirements for the degree of Master of Science specializing in Mechanical ... the thoroughness of these inspections The application of robotic systems for structural health monitoring may provide a successful means of improving the efficiency and accuracy of structural integrity ... assisting human efforts This work describes the development of an autonomous robotic system for the inspection of steel bridge girders This system serves as a mobile platform for structural health...
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A063 precast concrete pier systems for rapid construction of bridges in seimic regions
Ngày tải lên :
31/10/2016, 21:34
... 10.1: 10.2: 10.3: Comparison of Performance of Reinforced Concrete and Hybrid Frames .205 Sensitivity of Performance, Reinforced Concrete Frames 207 Sensitivity of Performance, Hybrid Frames ... Details for Complete Opening Connection for Reinforced Concrete Frames 33 Column and Cap-Beam for Complete Opening Connection for Reinforced Concrete Frames 34 Elevation of ... Reinforced Concrete Frames 24 Cap-Beam Details for Slotted Opening Connection for Reinforced Concrete Frames 29 Column and Cap-Beam for Slotted Opening Connection for Reinforced...
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Báo cáo y học: "Improved methods for the mathematically controlled comparison of biochemical systems" docx
Ngày tải lên :
13/08/2014, 22:22
... representation offers two key advantages in the performance of controlled comparisons First, S -systems have a form that allows for the algebraic determination of the system's steady state by solution of ... margin of local stability are easily determined and often form the basis of functional performance measures used in controlled comparisons Logarithmic gains represent the change Page of 18 (page ... framework provides for a straightforward mapping of biochemical pathway maps into systems of equations The pathway and equations for cases A and B differ only in the feedback inhibition of the first...
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Composite controlled release system of nitric oxide for cardiovascular tissue engineering application
Ngày tải lên :
10/09/2015, 09:08
... COMPOSITE CONTROLLED RELEASE SYSTEM OF NITRIC OXIDE FOR CARDIOVASCULAR TISSUE ENGINEERING APPLICATION ZHANG QINYUAN B.Eng (Hons), National University of Singapore A THESIS SUBMITTED FOR THE DEGREE OF ... main isoform classes with different regulation and activities [133, 144] One main class is the constitutive class, which is made up of the neuronal isoform (nNOS) and the endothelial isoform (eNOS) ... a trend to make use of nanoparticles in controlled release of NO Fumed silica nanoparticles and gold nanoparticles have been modified to release NO through derivatisation of the particle’s surface...
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Controlled release alginate based microparticulate systems for drug delivery and chemoembolization
Ngày tải lên :
13/09/2015, 20:39
... successful formulation of a stable and effective dosage form therefore depends on the careful selection of excipients The use of polymers in the formulation of controlled drug delivery systems has over ... employed to solve the problem of rapid drug release A key consideration in the modification of drug delivery systems is the controlled release of drug at the site of action For example, additives such ... 1995) C3 Drug release mechanisms of controlled release delivery system Drug release mechanisms depend on the properties of the polymeric carrier, drug and additives present The release of drug from...
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The evaluation of bioactive polycaprolactone scaffolds as protein delivery systems for bone engineering applications
Ngày tải lên :
15/09/2015, 17:10
... is submitted for the degree of Doctor of Philosophy in the Department of Oral & Maxillofacial Surgery at the National University of Singapore under the supervision of Associate Professor Ho Kee ... evaluation of PCL-TCP composites as delivery systems for platelet-rich plasma Journal of Controlled Release 2005; 107(2): 330-342 Y Lei, B Rai, K.H Ho and S.H Teoh In vitro degradation of novel bioactive ... scaffolds showed sustained release of the growth factors and total release was not achieved, whereas total release was realized for PBS-soaked scaffolds Only release profiles for SBF-soaked scaffolds...
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Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"
Ngày tải lên :
26/10/2012, 10:04
... IC50 values of 30 µM for hSGLT1 and 10 µM for hSGLT2, while thioglycoside VII showed IC50 values of 15 µM for hSGLT1 and 88 µM for hSGLT2 These data confirm the strong inhibitory effects of thioglycoside ... notion of using SGLT inhibitors as a means to control circulating levels of glucose The selective inhibition of hSGLT2 by thioglycoside I, which is responsible for most of the reabsorption of glucose ... used to determine the amount of ATP in mg of protein measured from the number of cells per well After 24 h, the microtiter plate was taken for scintillation counting of radioactive [14C]AMG using...
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Release of anti-cyanobacterial allelochemicals from aquatic and terrestrial plants applicable for artificial floating islands
Ngày tải lên :
05/09/2013, 09:38
... Hishikaki, Japan) Confirmation of the release of anti-cyanobacterial allelochemicals In order to confirm the release of anti-cyanobacterial allelochemicals, the culture solution of each plant was subjected ... of M aeruginosa by 50% of the control, denoted as EC50, was > 10 mg/L for VA, mg/L for PCA, and 1.0 mg/L for GA This indicates that VA, PCA, and GA can contribute to the allelopathic effect of ... compounds For example, Quayyum et al (2000) confirmed growth inhibition of rice (Oryza satives) seedlings by water extracts of C rotundus and leachate of its leaves, and found the existence of phenolic...
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Diffusion of photovoltaic systems for rural electrification in Thailand
Ngày tải lên :
05/09/2013, 16:10
... three main formats according to the informants One format of the interview guide is for officers from eight governmental agencies who are the subjects of the overall case The second format aims ... Office of the Basic Education Commission (OBEC); iv Office of the Non-formal and Informal Education (ONIE); v Vocational Education Commission (VEC); NSTDA (2008) Memorandum of understanding for ... is that the transformation to sustainable forms of energy in rural areas of developing countries may take time and need a lot of efforts Even if the energy is provided for free of charge, there...
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22 global optimization for parameter estimation of dynamic systems lin chinese 2005
Ngày tải lên :
12/01/2014, 22:03
... can be used to estimate the parameters of dynamic systems • A validated solver for parametric ODEs is used to construct bounds on the states of dynamic systems • An efficient constraint propagation ... Construct Taylor models of the states using a new validated solver for parametric ODEs (VSPODE) (Lin and Stadtherr, 2005) – Compute the Taylor model Tφ of the objective function – Perform constraint ... where, S is the interval bound of other terms by direct evaluation Taylor Models - Constraint Propagation • Goal – to reduce part of domain not satisfying c(x) ≤ • For some i = 1, · · · , m bi...
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Global optimization for parameter estimation of dynamic systems lin chinese 2005
Ngày tải lên :
12/01/2014, 22:16
... can be used to estimate the parameters of dynamic systems • A validated solver for parametric ODEs is used to construct bounds on the states of dynamic systems • An efficient constraint propagation ... Construct Taylor models of the states using a new validated solver for parametric ODEs (VSPODE) (Lin and Stadtherr, 2005) – Compute the Taylor model Tφ of the objective function – Perform constraint ... where, S is the interval bound of other terms by direct evaluation Taylor Models - Constraint Propagation • Goal – to reduce part of domain not satisfying c(x) ≤ • For some i = 1, · · · , m bi...
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