systemic treatment of breast cancer

... Systemic Treatment of Malignant Melanoma IX Systemic Treatment of Renal Cell Carcinoma X Systemic Treatment of Lung Cancer XI Systemic Treatment of Gastric Cancer XI1 Systemic Treatment ... XVI Systemic Treatment of Brain Tumors XVII Systemic Treatment of Neuroblastoma XVIII Systemic Treatment of Prostate Carcinoma XIX Systemic Treatment of Carcinoma of the Uterine ... Treatment of Myelomatosis Systemic Treatment of Kaposi's Sarcoma Systemic Treatment of Soft Tissue Sarcomas 119 134 141 146 149 152 vi i CONTENTS VII Systemic Treatment of Osteosarcomas...

Ngày tải lên: 20/01/2016, 03:47

... to improve the effectiveness of systemic chemotherapy The novel strategy that I propose here to improve the effectiveness of systemic chemotherapy in the treatment of malignant brain tumors is ... limit of pore size in the BBTB of the microvasculature of early, less mature and smaller malignant brain tumor colonies is to nanometers lower than that of the BBTB of the microvasculature of late, ... randomized trial of surgery in the treatment of single metastases to the brain New England Journal of Medicine 1990, 322:494 Jellinger K, Volc D, Grisold W: Multimodality treatment of malignant gliomas...

Ngày tải lên: 18/06/2014, 15:20

... I is Professor of Clinical Psychology in the Department of Psychology at the University of Montreal Fearing Others The Nature and Treatment of Social Phobia Ariel Stravynski University of Montreal ... disruptive social anxiety are features of the lives of many thousands of people But exactly what is social phobia? What causes it? What is its nature and what kinds of treatments can improve it? Using ... and ways of testing them 81 5.3 Reliability: agreeing about the entity of social phobia 86 5.4 Predictors of response to treatment 95 5.5 Social phobia in the family 99 5.6 Association of social...

Ngày tải lên: 21/09/2012, 10:54

... avoiding Page of 10 (page number not for citation purposes) proarrhythmic drugs Reduction of the systemic inflammatory state is tempting but is of course always the purpose of ICU treatment The ... by insufficient treatment of AF or, on the contrary, is caused by adverse effects of the treatment, however, is too realistic to be ignored All we have stated about the treatment of AF in MICU ... disease and other nosocomial complications Can treatment of atrial fibrillation improve survival? There are few data on the effect of treatment of AF on mortality in ICU patients A meta-analysis...

Ngày tải lên: 25/10/2012, 10:35

... Antipsychotics [29] Initiation of Treatment First Year of Treatment Duration of Treatment • Baseline fasting glucose level • Fasting glucose level every 3–4 months • Observe for signs of hyperglycemia • ... of our patients develop renal disease, psychiatrists must be aware of the effects of psychotropics on the kidneys, as well the effects of decreased renal functioning on the pharmacokinetics of ... bioavailability of free, active highly protein-bound drugs Accumulation of active hydroxylated metabolites of carbamazepine may lead to symptoms of drug toxicity despite therapeutic drug levels [70] Of all...

Ngày tải lên: 25/10/2012, 10:51

... mind, in the presence of adherent scars, after having infiltrated the whole area with a solution of Lidocaine 0.5% and Epinephrine 1:200,000 very close to one of the two edges of the scar, a small ... that brings great improvement to the treatment of depressed scars AUTHORS' CONTRIBUTIONS FI: participated in the surgical treatment and in the follow-up of this patient MT: drafted the manuscript ... literature FMA: participated in the surgical treatment and in the follow-up of this patient MM: participated in the design of this case study and in the follow-up of this patient ADI: revised the literature...

Ngày tải lên: 25/10/2012, 11:00

... Position of Occlusion Begnning of the CCA Begnning of the CCA Begnning of the ICA Left cavernous sinus part of the ICA, right beginning of the ICA Begnning of the ICA Symptom Other aeurysms SAH PCA SAH ... sclerosis of the CCA PCA VA→ECA→IC A Present case 2010 69/F Arterio- Begnning SAH sclerosis of the ICA No No Year Age/ Cause gender 41/F aortitis 63/M Position of Occlusion Begnning of the CCA ... arteries The angiograph of the vertebral artery showed no delay in the blood flow of anterior circulation The saccular aneurysm with a diameter of 3.2 mm was observed at the apex of the basilar artery...

Ngày tải lên: 25/10/2012, 11:04

... Different methods of decompressive craniectomy in the treatment of TBI Different methods of decompressive craniectomy have been developed for, or applied to, decompression of the brain at risk ... most authors.11, 26 The temporary removal of a piece of skull followed by loose closure of the dura and skin layers presumably allows for expansion of the edematous brain into a durotomy “bag” ... comes down to the floor of the middle cranial fossa, at the root of the zygoma; this ensures adequate lateral decompression of the temporal lobe, allowing it to “fall out” of its usual calvarial...

Ngày tải lên: 25/10/2012, 11:40

... indication of techniques for the treatment of this kind of surgical complication Spontaneous healing of to mm openings can occur, while untreated larger defects are connected with the pathogenesis of ... attention for the presence of sporadic intraoral drainage in posterior left maxilla The discomfort was of a few years duration and had its origin following an endodontic treatment of tooth 2.6 provided ... characteristics of OAC/OAF; the apexes of tooth 26 were in extremely close approximation to the maxillary sinus, and an area of periapical rarefaction was evident (Fig 1) After the failure of the endodontic...

Ngày tải lên: 25/10/2012, 11:48

... restraints of the surgery RESULTS A total of 174 people (77 women, 97 men; mean age 64, range 22-89) were included Length of follow-up was at least years with a maximum of years Location of facet ... the treatment of low back syndrome Pain 1977;3:257-63 Savitz MH Percutaneous radiofrequency rhizotomy of the lumbar facets: ten years' experience Mt Sinai J Med 1991;58:177-8 Schaerer JP Radiofrequency ... elsewhere as treatment prior to considering the endoscopic option The facet injections in these 72 patients gave 50 to 100% relief of their pain in 86% of the patients with a median relief period of months...

Ngày tải lên: 26/10/2012, 09:32

... objectives adaptation and the development of new forms of treatment are necessary This team is composed of the lymphologist or professional trained in the treatment of lymphedema, psychologists, nutritionists, ... was developed for the treatment of the lower extremities by producing dorsoflexion of the foot and allows treatment sessions of hours or more daily with losses of as much as 20 cm in circumference ... research of lymphedema with excellent results attending the necessities of patients from distant localities This option of simple and feasible treatment can change the lives of millions of people...

Ngày tải lên: 26/10/2012, 09:39

... adhered to the dosing schedule less than 75% of the time Method of assigning patients to treatment groups Patients were assigned to treatment groups (order of treatments) using computer-generated randomization ... ingredients Use of concomitant prohibited medication (narcotics, oral NSAIDs, topical NSAIDs) within four weeks of randomization Use of acetaminophen or ibuprofen within days of randomization ... thus compromising the quality of life of millions of Americans In addition, OA costs the North American economy approximately $60 billion per year Current treatment of OA includes exercise, heat/cold...

Ngày tải lên: 26/10/2012, 09:48

... efficient treatment option even for deep wound infections The most important advantages of this system are an increased localised blood flow, the reduction of tissue bacterial counts, elimination of ... facilitated, which leads to a significant reduction of the bacterial count The efficacy of the V.A.C therapy has been 245 proven in the treatment of wound infections Fleischmann et al could show ... arthroplasty by means of the conventional V.A.C.-system at a mean follow-up of 21 months [6] Kirr et al showed good results in cases by using the V.A.C.-Instill® system in the treatment of early infections...

Ngày tải lên: 26/10/2012, 09:53

... order to avoid fracture of the cement spacer [27] The implantation of an ALC spacer shortens the duration of systemic antibiotic therapy which lessens the likelihood of systemic toxicity and may ... time of reimplantation and allow delivery of the antibiotics of choice according to sensitivities [23,36] The disadvantage of a static spacer is that it does not allow physiological motion of the ... substantial impairment of patients’ normal daily activities during the prolonged course of treatment Another drawback of the static spacer is bone loss attributed to migration of the block spacer...

Ngày tải lên: 26/10/2012, 09:53

... of soft-tissue shortening and provision of sufficient infection therapy is the usage of temporary, antibiotic-loaded cement spacers [5, 7, 14, 24] Although their indication in the treatment of ... the diagnosis of an osteomyelitis of the femoral head Table 1: Patients’ data, surgical procedures, and causative organisms at the site of hip spacer implantation in the treatment of coxitis and ... Fig 2: Evaluation of the hip joint function by the Merle d’ Aubigne score at the site of spacer implantation in the treatment of proximal femur infections Fig 3: Evaluation of the hip joint function...

Ngày tải lên: 26/10/2012, 09:53

... retrospective evaluation of the patients’ records did not allow any differentiation of the particular cause of the renal failure, respectively (antibiotic-impregnation of the spacer, systemic antibiotics, ... properties of gentamicin-loaded hip spacers after insertion of Kirschner wires [31] Stress experiments showed an average failure load of 1.6 kN The insertion of the K-wires prevented any dislocation of ... review of the literature South Med J 2007; 100: 712-6 Cabrita HB, Croci AT, Camargo OP, Lima AL Prospective study of the treatment of infected hip arthroplasties with or without the use of an...

Ngày tải lên: 26/10/2012, 09:53

... with endoscopic laminoforaminoplasty via a small incision, of less than one inch Materials and Methods Twelve patients were treated with endoscopic laminoforaminoplasty (ELFP) of the thoracic spine ... small study group Conflict of Interest The authors have declared that no conflict of interest exists References Kunogi J, Hasue M Diagnosis and operative treatment of intraforaminal and extraforaminal ... neural structures increases the risk of adverse events with invasive approaches Open surgical correction is the current standard of care for foraminal stenosis of cervical and lumbar vertebrae Open...

Ngày tải lên: 26/10/2012, 09:57

... viral loads baseline The lack of EVR is equally predictive of NR (98%) allowing a decision to stop treatment if this criteria is not met [15] Cirrhotics Treatment of non-decompensated cirrhotics ... phase of the some of the maintenance studies Furthermore, some trials now define non-responder as early as 12 or even weeks modifying treatment with either stronger treatment or longer treatment ... consensus interferon 15 ug daily for months followed by 15 ug TIW for the remainder of treatment for a total of 15 months of treatment RNA negativity at 12, 24 and 48 weeks was 23, 31 and 43 % SVR was...

Ngày tải lên: 02/11/2012, 09:48

... reduction of the platelet count with at least 50 % of the baseline value, and treatment failure (F) as a reduction of the platelet count with < 50 % of the baseline value Here, and for the purpose of ... of TPO, the major cytokine involved in the regulation of megakaryocyte and platelet growth and release, was raised at six months of anagrelide treatment; concomitantly there was a reduction of ... model of action of TPO with its receptor on target cells It is well established that serum levels of TPO are regulated by the binding of the ligand to the receptor and the endocytosis of the...

Ngày tải lên: 03/11/2012, 10:52

Ngày tải lên: 03/11/2012, 11:01