systemic lupus erythematosus scleroderma and polymyositis dermatomyositis

... Increased T-lymphocyte apoptosis/necrosis and IL-10 producing cells in patients and their spouses in Icelandic systemic lupus erythematosus multicase families Lupus 2002, 11:435-442 Herrmann M, Voll ... GC: Abnormal T cell signal transduction in systemic lupus erythematosus Arthritis Rheum 2002, 46:1139-1154 Walport MJ: Complement and systemic lupus erythematosus Arthritis Res 2002, (Suppl):S279-S293 ... Isenberg DA: Cytokines and systemic lupus erythematosus Ann Rheum Dis 2000, 59:243251 Ytterberg SR, Schnitzer TJ: Serum interferon levels in patients with systemic lupus erythematosus Arthritis...

Ngày tải lên: 09/08/2014, 01:21

... germinal centre (GC) A and GC B, and B-cell clusters C and D were derived Groups of sequences were deemed to be clonally related when they used the same V, D, J and CDR3, and differed only by base ... from each of the systemic lupus erythematosus splenic germinal centres and Bcell clusters GC A GC B (a) Location GC/cluster Total VH Segment Framework VH5-51 VH2-5*02 10 CDR1 and CDR2 a b a A ... subjects and patients with systemic lupus erythematosus Int Arch Allergy Immunol 2000, 123:36-45 27 de Wildt RMT, Tomlinson IM, van Venrooij WJ, Winter Ga, Hoet RMA: Comparable heavy and light...

Ngày tải lên: 09/08/2014, 01:21

... erythematosus patients systemic TNF stimulation on gene expression in healthy individuals Effect of TNF stimulation on gene expression in healthy individuals and and systemic lupus erythematosus patients ... mononuclear cells (PBMCs) from six systemic lupus erythematosus (SLE) patients and three healthy individuals (HI) were isolated and stimulated for 24 hours in the absence and presence of 20 ng/ml TNF ... interleukin-12 and other Th1-type cytokines in patients with recent-onset systemic lupus erythematosus Arthritis Rheum 1998, 41:838-844 Liu TF, Jones BM: Impaired production of IL-12 in system lupus erythematosus...

Ngày tải lên: 09/08/2014, 01:22

... Prevalence and risk factors of carotid plaque in women with systemic lupus erythematosus Arthritis Rheum 1999, 42:51-60 Salmon JE, Roman MJ: Accelerated atherosclerosis in systemic lupus erythematosus: ... asymptomatic patients with systemic lupus erythematosus Am J Med 1984, 77:286-292 Shome GP, Sakauchi M, Yamane K, Takemura H, Kashiwagi H: Ischemic heart disease in systemic lupus erythematosus A retrospective ... cardiovascular risk factors in systemic lupus erythematosus J Musculoskel Med 1998, 15: 42-52 El-Magadmi M, Ahmad Y, Wajed J, Bruce IN: The bimodal mortality pattern in systemic lupus erythematosus Curr...

Ngày tải lên: 09/08/2014, 01:22

... classification of systemic lupus erythematosus [letter] [see comments] Arthritis Rheum 1997, 40:1725 32 Trysberg E, Nylén K, Rosengren LE, Tarkowski A: Neuronal and astrocytic damage in systemic lupus erythematosus ... M, Hardin JG, Michalski JP: Systemic lupus erythematosus and dementia Psychol Rep 1998, 83:1034 Jonsson H, Nived O, Sturfelt G: Outcome in systemic lupus erythematosus: a prospective study of ... CY: The study of anticardiolipin antibodies and interleukin-6 in cerebrospinal fluid and blood of Chinese patients with systemic lupus erythematosus and central nervous system involvement Autoimmunity...

Ngày tải lên: 09/08/2014, 01:23

... criteria for the classification of systemic lupus erythematosus Arthritis Rheum 1982, 25:1271-1277 16 Jonsson H, Nived O, Sturfelt G: Outcome in systemic lupus erythematosus: a prospective study ... et al.: The development and initial validation of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index for systemic lupus erythematosus Arthritis ... patients with systemic lupus erythematosus: association with clinical symptoms Arthritis Rheum 1998, 41:1181-1189 25 Sturfelt G, Hellmer G, Truedsson L: TNF microsatellites in systemic lupus erythematosus- a...

Ngày tải lên: 09/08/2014, 01:24

... a candidate chromosome region to human systemic lupus erythematosus J Clin Invest 1997, 99:725-31 Lander ES, Kruglyak L: Genetic dissection of complex traits: guidelines for interpreting and ... Arthritis and Rheumatism Campaign References Block SR, Winfield JB, Lockshin MD, D’Angelo WA, Christian CL: Studies of twins with systemic lupus erythematosus: A review of the literature and presentation ... revised estimate of twin concordance in systemic lupus erythematosus Arthritis Rheum 1992, 35:311-318 Arthritis Research 10 11 12 13 14 15 Vol No Barton and Worthington Vyse TJ, Todd JA: Genetic...

Ngày tải lên: 09/08/2014, 03:24

... of systemic lupus erythematosus Arthritis Rheum 1982, 25:1271-1277 Petri M, Magder L: Classification criteria for systemic lupus erythematosus: a review Lupus 2004, 13:829-837 Rekvig OP, Andreassen ... of systemic lupus erythematosus N Engl J Med 2003, 349:1526-1533 18 Isenberg DA, Ravirajan CT, Rahman A, Kalsi J: The role of antibodies to DNA in systemic lupus erythematosus – a review and ... Andreassen K, Moens U: Antibodies to DNA – towards an understanding of their origin and pathophysiological impact in systemic lupus erythematosus Scand J Rheumatol 1998, 27:1-6 Kaliyaperumal A, Mohan...

Ngày tải lên: 09/08/2014, 06:22

... cells and the different subpopulations Data are given for healthy individuals (con) and for each of the patient groups analyzed: osteoarthritis (OA), rheumatoid arthritis (RA) and systemic lupus erythematosus ... The percentages of CXCR5+ and CXCR3hi B cells are given for healthy controls (con) and patients with osteoarthritis (OA), rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) 0.2 0.1 ... concentrations in sera Sera of healthy controls and of sera patients with rheumatoid arthritis, systemic lupus erythematosus and osteoarthritis were tested in a standard ELISA test A D450 of 0.06 corresponds...

Ngày tải lên: 09/08/2014, 06:23

... populations Materials and methods Mice and sera Female NZW and male BXSB mice were purchased, respectively, from Bomholtgard Breeding and Research Center (Ry, Denmark) and The Jackson Laboratory ... Anti-NPM-antibody-positive systemic lupus erythematosus (SLE) sera yielded homogeneous nuclear and nucleolar staining (e) The nucleolar staining was abrogated when the mAb and sera from mouse (b,d) ... antibody systemic lupus erythematosus (SLE) (a) and a male WB mouse (c) using a 2D PAGE-separated HL-60 cell protein map as the substrate (b,d) Mass spectra of the proteins bound by the SLE (b) and...

Ngày tải lên: 09/08/2014, 07:20

... staining and flow cytometry for ICOS expression Percentages of ICOS+ cells (panels c and d) and MFIs of ICOS+ cells (panels e and f) are shown CD4+CD45RO+ (panels c and e) and CD8+CD45RO+ (panels d and ... cells and CD8+CD45RO+ICOS+ cells, respectively, were as follows: active SLE, 1.80 and 1.25; inactive SLE, 0.45 and 0.40; and normal control individuals, 1.10 and 0.50 *P < 0.05, **P < 0.01, and ... pathogenesis of systemic lupus erythematosus In Dubois' Lupus Erythematosus Edited by: Wallace DJ, Hahn BH Baltimore, MA: Williams & Wilkins; 1997:69-76 Rekvig OP, Nossent JC: Anti-double-stranded DNA...

Ngày tải lên: 09/08/2014, 07:20

... response to DNA in murine systemic lupus erythematosus Scand J Immunol 2003, 57:525-533 Izui S, Lambert PH, Fournie GJ, Turler H, Miescher PA: Features of systemic lupus erythematosus in mice injected ... Stephan H, Mannherz HG, Moroy T: Features of systemic lupus erythematosus in Dnase1-deficient mice Nat Genet 2000, 25:177-181 Walport MJ: Lupus, DNase and defective disposal of cellular debris Nat ... (rhDNase) in patients with lupus nephritis Lupus 1999, 8:68-76 Macanovic M, Sinicropi D, Shak S, Baughman S, Thiru S, Lachmann PJ: The treatment of systemic lupus erythematosus (SLE) in NZB/W...

Ngày tải lên: 09/08/2014, 07:20

... the data and helped to draft the manuscript YA obtained consent from patients and collected the samples and patient data for the study, and participated in the coordination of the study and writing ... SLE: effects of interleukin-2 and transforming growth factor-beta Lupus 1999, 8:95-102 Bruce IN, Gladman DD, Urowitz MB: Premature atherosclerosis in systemic lupus erythematosus Rheum Dis Clin ... factor beta in atherosclerosis: novel insights and future perspectives Curr Opin Lipidol 2002, 13:523-529 Hahn BH: Systemic lupus erythematosus and accelerated atherosclerosis N Engl J Med 2003,...

Ngày tải lên: 09/08/2014, 08:22

... lanes Ki and rP/Ki/his) and U1snRNP-A (U1-A, lanes nRNP and Ku/nRNP), RPA70 co-migrates with Ku p70 (lanes Ku/nRNP and Ku), and RPA14 co-migrates with histone H4 (lanes rP/Ki/his, Histones, and BM6.5) ... included 276 patients with SLE, 43 with polymyositis/ dermatomyositis (PM/DM), 47 with scleroderma (systemic sclerosis (SSc)), 35 with rheumatoid arthritis (RA), and 40 with SjS Diagnosis was established ... components of RPA; of the remainder, one reacted with RPA70 and RPA32, one reacted with RPA14 only, and one was negTable Systemic lupus erythematosus criteria of cases with anti-RPA Criterion Case...

Ngày tải lên: 09/08/2014, 08:22

... SLEDAI, Systemic Lupus Erythematosus Disease activity index; SLICC, Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index for systemic lupus erythematosus ... pre-selected systemic lupus erythematosus group with and without Box plot of the optical density (OD) of α-actinin binding in patients from pre-selected systemic lupus erythematosus group with and without ... Rekvig OP, Andreassen K, Moens U: Antibodies to DNA– towards an understanding of their origin and pathophysiological impact in systemic lupus erythematosus Scand J Rheumatol 1998, 27:1-6 Hernando M,...

Ngày tải lên: 09/08/2014, 08:23

... organs [6] and is inducible by cells of myeloid origin (monocytes, macrophages, neutrophils, and dendritic cells) and also by osteoclasts (reviewed by Ng and colleagues [3] and Dillon and colleagues ... cytokine levels and B-cell frequency (a) Two patients with systemic lupus erythematosus (SLE) (S5 and S14) representing the frequency relation of B-cell frequency (left y-axis in diagrams) and cytokine ... design, acquired, analysed and interpreted data, prepared the manuscript, and performed statistical analysis MH and IG selected and collected samples and interpreted and provided clinical data...

Ngày tải lên: 09/08/2014, 08:23

... Groningen, The Netherlands) and CD133 (Miltenyi Biotec, Utrecht, The Netherlands) Cells were washed and resuspended in PBS Measurements were performed on the FACSCalibur and CellQuest software ... of patients and participated in design and drafting of the manuscript MH participated in the design and coordination of the study and helped to draft the manuscript All authors read and approved ... infarction and angina in women with systemic lupus erythematosus: comparison with the Framingham Study Am J Epidemiol 1997, 145:408-415 23 24 Ward MM: Premature morbidity from cardiovascular and cerebrovascular...

Ngày tải lên: 09/08/2014, 10:20

... patients with systemic Lupus erythematosus A study of 60 cases Eur J Obstet Gynecol Reprod Biol 1999, 83:137-142 Johns KR, Morand EF, Littlejohn GO: Pregnancy outcome in systemic lupus erythematosus ... records in their possession, and these were used to validate clinical criteria and medical history Ascertainment of women without systemic lupus erythematosus For each case, randomly chosen households ... AE, Gordon C, Palmer RG, Bacon PA: The prevalence and incidence of systemic lupus erythematosus in Birmingham, England Relationship to ethnicity and country of birth Arthritis Rheum 1995, 38:551-558...

Ngày tải lên: 09/08/2014, 10:22

... enhanced in patients with systemic lupus erythematosus and is associated with arterial and renal disease manifestations Arthritis Rheum 2005, 52:192-200 Wu R, Nityanand S, Berglund L, Lithell ... Hayem G, Nicaise-Roland P, Palazzo E, de Bandt M, Tuback F, Weber M, Meyer OI: Anti-oxidized low-density lipoprotein (OxLDL) antibodies in systemic lupus erythematosus with and without antiphospholipid ... lipoproteins (HDLs) isolated from healthy controls (left column) and patients with systemic lupus erythematosus (SLE) (middle column) and rheumatoid arthritis (RA) (right column) Numbers below 1.0...

Ngày tải lên: 09/08/2014, 10:23

... disease activity and lupus nephritis in patients with systemic lupus erythematosus Arthritis Rheum 2006, 54:2951-2962 Crow MK: Interferon pathway activation in systemic lupus erythematosus Curr ... interferon-inducible gene transcripts and dendritic cell maturation in systemic lupus erythematosus Clin Immunol 2005, 117:238-250 51 Crow MK, Kirou KA: Interferon-alpha in systemic lupus erythematosus Curr Opin ... DR antigen expression in systemic lupus erythematosus Clin Exp Rheumatol 1984, 2:131-137 57 Banchereau J, Pascual V: Type I interferon in systemic lupus erythematosus and other autoimmune diseases...

Ngày tải lên: 09/08/2014, 10:23