systemic evidence based reviews as the basis of guidelines

... research, the value of a meta-analysis is directly dependent on the validity of each of the data points In other words, the quality of the meta-analysis can only be as good as the quality of the research ... at an unbiased assessment of the best course of action Assessment of appropriate medical care should instead be derived through evidence- based process The role of the practitioner, then, is not ... the sensitivity and the specificity of the imaging test The third step is to incorporate the physician into the evaluation of the imaging intervention by evaluating the effect of the use of the...

Ngày tải lên: 30/05/2014, 23:55

... evidence- based practice, effect of organizational support for evidencebased practice on provider attitudes toward evidence- based practice, and effect of organizational support for evidence- based ... for evidence- basedagency type on Path model of evidence- based practice, effect of organizaand Path model of partial mediation effects of agency type on organizational support for evidence- based ... (one-tailed) Figure evidence- based evidence- based practice effect of provider attitudes toward partial tudes toward support for evidence- basedon provider attiorganizational evidence- based practice,...

Ngày tải lên: 11/08/2014, 05:21

... by the authors to document the proceedings of the 2007 IOM Annual Meeting   EVIDENCE- BASED MEDICINE of the national domestic agenda, the choice of EBM by the IOM Council as the theme of the ... application, as well as the prospect of new ways of meeting the need, provides the back-drop for the discussions at the 37th Annual Meeting of the Institute of Medicine (IOM) Entitled Evidence- Based ... 2006, the IOM convened the Roundtable on Evidence- Based Medicine Over the last years, the Roundtable has ex- 36 EVIDENCE- BASED MEDICINE plored, through its series of meetings and workshops on the...

Ngày tải lên: 06/03/2014, 09:20

... chronic asymptomatic disease They have a rash on their elbow and a little ringing in their ear and they’ll often consume time just unloading their frustrations If, on the other hand, there was an ... thiazides to at least one patient as a result of the intervention Their descriptions of the influence of the intervention can be broadly categorized into three themes: reinforced their existing ... inform their prescribing behavior (Table 2) Since the intervention was focused on influencing their prescribing behavior, the list of sources offered insight into the providers’ perceptions of other...

Ngày tải lên: 10/08/2014, 10:22

... chronic asymptomatic disease They have a rash on their elbow and a little ringing in their ear and they’ll often consume time just unloading their frustrations If, on the other hand, there was an ... thiazides to at least one patient as a result of the intervention Their descriptions of the influence of the intervention can be broadly categorized into three themes: reinforced their existing ... inform their prescribing behavior (Table 2) Since the intervention was focused on influencing their prescribing behavior, the list of sources offered insight into the providers’ perceptions of other...

Ngày tải lên: 11/08/2014, 05:21

... What was the content of the change at the project level, e.g., what in the system was changed to enhance, support and sustain use of an individual, targeted piece of evidence? What was the content ... the summarized findings will be used to assess each of the three RU/EBP models as to their degree of inclusiveness of key contextual elements identified by the case study These results will then ... use of a case study lies in the opportunity to collect multiple types of data enabling development of a comprehensive, in-depth picture of the influences of context on the routine use of evidence...

Ngày tải lên: 11/08/2014, 05:22

... improvement in their DAS28 The PPV of the administrative data -based effectiveness algorithm was 75%, and the NPV was 90% The sensitivity of the effectiveness algorithm was 75%, and its specificity was 90% ... disease activity scores (DAS), as assessed by physicians using the DAS28 [23] and the Clinical Disease Activity Index (CDAI) [24], as well as a bio-repository with banked DNA, serum, and plasma ... Table Varying a hypothetical response rate as measured by the algorithm from 30 and 60%, the amount of bias compared to the true response rate ranged from – 21% The results of the second sensitivity...

Ngày tải lên: 25/10/2012, 10:45

... was to present a novel laboratory method determining the hydraulic permeability of sand layer based on the capillary rise (CR) theory In nature, this method was also based on the Darcy’s law The ... when the initial filling height of sand samples was lower than 20 cm, the inhibition effect of the gas among the pores on the capillary pressure during the CR process tended to be increasing, thereby ... of 0.3-0.4mm It can be seen that at the initial stage, there was a good agreement between the measured and prediction results by the Washburn equation of h ~ t When the inflection point S was...

Ngày tải lên: 05/09/2013, 17:03

... aspirations of the educated man The opinion of the Greek mind itself as to the character of the knowledge of God, to which the thought of their race had led them at the beginning of the Christian era was ... questions within the scope of the Christian Faith The function of the age of the Councils was the formulation and definition of Christian dogma upon the admitted basis of the revelation of Jesus Christ ... those of atheism, because of their rejection of the gods of Greece and Rome; of immorality, because of the secrecy and mystery of their meetings, and cannibalism, because of their doctrine of the...

Ngày tải lên: 21/02/2014, 08:20

... grafting of the CDR loop of antilysozyme VHH functionalized NCS without denaturation, although the thermal stability was decreased and the affinity for lysozyme was weaker than in the original VHH The ... different species [23–25] The success of the series of studies shows that the stable framework structure of Fv enables the transfer of function by means of CDR replacement Barbas et al first designed ... functionalized the antibody fragments, but expression of the fragment was decreased and the binding affinity was weakened This might imply the importance of library approaches in specific local areas to...

Ngày tải lên: 06/03/2014, 11:20

... metzincin subfamily of metalloendopeptidases, the astacin family [32] The main functions of BMP1 ⁄ TLD-like metalloendopeptidases are ascribed to the proteolytic removal of C-propeptides from ... C protease as well as an activator of lysyl oxidase Therefore, an important role for hmeprina ⁄ b may be ascribed to tissue remodelling processes through the targeted regulation of ECM assembly ... metalloendopeptidases On the basis of our findings, hmeprin may be considered as a signalling protease mediating direct and indirect cleavage and signal transduction functions as well as degrading of a number...

Ngày tải lên: 07/03/2014, 06:20

... depending on the verb class they occur with Second, we believe that adjuncts can be at least as revealing of verbal meaning as complements are: many of them are not productive (in the sense that they ... determined by the semantics of the corresponding NP These cases code an other semantic role – cause – in the case of verbs of existence (Table 2) It is important to note that we not dispose of a preliminary ... p(t|v) = f (v) with f (v) being the frequency of the verb, and f (v, t) being the frequency of the verb in the frame These values have been calculated for each of the 150 verbs and 839 frame types...

Ngày tải lên: 08/03/2014, 03:20

... are based on the syntactic part of the constituent label The conversion program is the same as used for the CoNLL-2000 shared task (Tjong Kim Sang and Buchholz, 2000) Head words of chunks are assigned ... head of a chunk, or the dummy value NOFUNC for all non-heads For creating the POS -based task, all words are replaced by the goldstandard POS tags associated with them in the Penn Treebank For the ... is the number of features, is a weight for feature , and estimates the difference between the two instances’ values at the th feature The classes of the nearest neighbors then determine the class...

Ngày tải lên: 08/03/2014, 07:20

... pepper–red, strawberry–red, massage–oil, raspberry–red Table 3: A comparison of the document -based model and the log-likelihood ratio on the basis of the cue–target pairs with the largest difference ... log−likelihood statistic compound based syntax based document based q q 10 context size Figure 1: Median rank of the strong associations features of the type subject of fly covered eight syntactic ... For the syntax -based and word -based approaches, we only took into account features that occurred at least two times together with the target For the word -based models, we experimented with the...

Ngày tải lên: 08/03/2014, 21:20

... SVCs: the series of V1 to V3 and the series of V4 to V5 , because they not share their tenses The directional verb p©j ‘go’ performs as an adverb identi— fying the outward direction of the action ... determine the grammatical function (subject or object) of arbitrary np’s in (13) from the directionality (the subject on the left and the object on the right) With these reasons, I therefore adapted the ... respectively For example, the syntactic category 2< 3> s has a filler of type np on the left side and np np a gap of type np on the right side The filler 2d and the gap 3d of the same dic c rectionality...

Ngày tải lên: 08/03/2014, 21:20

... known as the Democratic Republic of Congo In these two instances the mortality rate was between 50 –90% Following those epidemics, Ebola hit Africa in many other instances the worst yet being in the ... motivation based on ideas of right and wrong when dealing with the geographical distribution of animals and plants  This concept of can be used to explain the world’s shockingly small response to the ... the September 11 bombings in the United States, the locality of this virus has become less isolated as the threat of bioterrorism looms large The Ebola virus is now on the “A” list for hopeful vaccination...

Ngày tải lên: 15/03/2014, 13:09

... independently of the ruling of law courts and of any human legislation The subject of the discussion was the lawfulness in any case at all of performing craniotomy, or of directly destroying the life of the ... following in the track of the wagon The farmer drove on faster, but they gained on him It was a desperate race to keep out of their reach At last they are just back of the wagon What can be done? The ... only for their own good, but also for the good of their patients and of the community at large The reasons are these: A The matters entrusted to their keeping are the most important of all earthly...

Ngày tải lên: 15/03/2014, 13:20

... of heat is released Thermodynamics is the science of the flow of heat and of its relationship to mechanical work The first law of thermodynamics is the principle of conservation of energy Energy ... 2003/10/30 — page 10 — #10 HEAT: THE THERMAL ENVIRONMENT 11 The magnitude of hc depends on the position of the surface, the direction of the heat flow and the velocity of the fluid For example • for ... with the mean temperature of the month, as Tn = 17.6 + 0.31 × To.av (1.7) where To.av is the mean temperature of the month (these coefficients are based on the work of Auliciems; several other...

Ngày tải lên: 29/04/2014, 15:42