synthesis of zsm 5 in the absence of any organic compound
Báo cáo khoa học: A single EF-hand isolated from STIM1 forms dimer in the absence and presence of Ca2+ ppt
Ngày tải lên :
07/03/2014, 00:20
... shown in Fig 1B, the distance between the two termini of the inserted Ca2+-binding sites in the model structure of the EF-hand of STIM1 is within ˚ 15 A Accordingly, a total of six glycine linkers ... subtracting the contribution of the baseline slope using logarithmic fitting The Tb3+-binding affinity of the protein was obtained by fitting normalized fluorescence intensity data using the equation: f ¼ ð½PT ... Ca2+-coordinating loop positions and was introduced to perturb the Ca2+-binding ability of the grafted EF-hand of STIM1 (B) Modelled structure of the engineered protein with the grafted EF-hand Ca2+-binding...
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Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot
Ngày tải lên :
08/03/2014, 23:20
... ATP into contact in the absence of ATP, curcumin is then able to bind to the ATPase (possibly at the hinge region) locking the two domains together and therefore precluding ATP binding (i.e inhibiting ... the ATPase on Lys5 15 within the ATP binding pocket of the nucleotide binding domain, also precluding ATP binding [ 15, 43] Therefore if curcumin affects this conformationally induced fluorescence ... concentrations of curcumin ( 25 mM ) the Km for the catalytic site is also possibly increased In order to further assess the possibility of curcumin affecting the interaction of ATP binding to the ATPase,...
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Báo cáo khoa học: Catalytic mechanism of the primary human prostaglandin F2asynthase, aldo-keto reductase 1B1 – prostaglandin D2 synthase activity in the absence of NADP(H) pptx
Ngày tải lên :
14/03/2014, 23:20
... for with lM 1-[14C]PGH2 in the absence of NADPH or NADP+ at pH 8 .5, and, for PGFS activity, in the presence of 0 .5 mM NADPH at pH 5. 5 to be 6.19 ± 0. 05 by nonlinear fitting of Eqn (1) (see Materials ... catalyzed the reduction of the 9,11-endoperoxide group of PGH2 to produce PGF2a in the presence of NADPH, which was defined as the PGFS activity, and the isomerization of PGH2 to PGD2 in the absence of ... PGD2 in the absence of NADPH or NADP+ and as an acid to generate PGF2a in the presence of NADPH Thus, this is the first report demonstrating the proton donor ⁄ acceptor function of His110 during the...
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Báo cáo khoa học: A steady-state competition model describes the modulating effects of thrombomodulin on thrombin inhibition by plasminogen activator inhibitor-1 in the absence and presence of vitronectin ppt
Ngày tải lên :
23/03/2014, 17:21
... PAI-1/VN complexes, suggests the involvement of the chondroitin sulphate of rl-TM in the binding of PAI-1/VN Indeed, both in the absence and presence of PAI-1, the interaction of rl-TM with immobilized ... binding of TM by thrombin Binding of the carboxy-terminal part of the reactive center loop of PAI-1 in the small cleft formed by the 60-loop and VR1 loop can be envisioned The kinetics of the interaction ... demonstrated in this study, binding of TM does sterically hinder PAI-1 binding to thrombin (–VR1tPA) Therefore, the binding of PAI-1 to thrombin either involves a small part of the VR1 loop that...
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Báo cáo khóa học: Protein assembly of photosystem II and accumulation of subcomplexes in the absence of low molecular mass subunits PsbL and PsbJ pdf
Ngày tải lên :
30/03/2014, 13:20
... complex of spinach Biochim Biophys Acta 977, 3 15 321 Shen, J.-R., Burnap, R.L & Inoue, Y (19 95) An independent role of cytochrome c -55 0 in cyanobacterial photosystem II as revealed 51 52 53 54 55 56 ... always hold true In rapidly expanding young leaves in particular, some of the PSII core proteins and all of the OEC proteins can accumulate in thylakoids in the absence of any assembly of PSII, as ... Dynamic interaction between the D1 protein, CP43 and OEC33 at the lumenal side of photosystem II in spinach chloroplasts: evidence from lightinduced cross-linking of the proteins in the donor-side...
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Báo cáo sinh học: " Clearance of low levels of HCV viremia in the absence of a strong adaptive immune response" pptx
Ngày tải lên :
18/06/2014, 18:20
... show the sum of SI values of the proliferation assay and the sum of specific interferon-gamma spots (spots in the presence of antigen – spots in the medium control) against individual HCV proteins ... cases (Table 1) We also investigated reactivity against single HCV proteins by the INNO-LIA HCV III assay A faint band against the C2 protein was found once in one of the four anti-HCV negative ... Table 5: Sequences of peptides used for the ELISPOT-screen in the Vienna laboratory at Intercell AG ID HCV antigen 1798 1799 1624 154 7 1827 1829 1846 1 754 18 35 1 855 1843 1844 1818 1838 155 7 NS4...
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Báo cáo hóa học: " Clearance of low levels of HCV viremia in the absence of a strong adaptive immune response" potx
Ngày tải lên :
20/06/2014, 01:20
... show the sum of SI values of the proliferation assay and the sum of specific interferon-gamma spots (spots in the presence of antigen – spots in the medium control) against individual HCV proteins ... cases (Table 1) We also investigated reactivity against single HCV proteins by the INNO-LIA HCV III assay A faint band against the C2 protein was found once in one of the four anti-HCV negative ... Table 5: Sequences of peptides used for the ELISPOT-screen in the Vienna laboratory at Intercell AG ID HCV antigen 1798 1799 1624 154 7 1827 1829 1846 1 754 18 35 1 855 1843 1844 1818 1838 155 7 NS4...
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Báo cáo y học: "Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells" ppsx
Ngày tải lên :
09/08/2014, 01:24
... the clone M2139 binding to the J1 epitope (amino acids 55 1 56 4) and an IgG2a antibody of the clone CIIC1 binding to the C1I epitope (amino acids 358 –363) was found to be more arthritogenic [5] , ... cells again did not affect the initiation phase of the disease; instead, the effect was noted in the more chronic phase of the disease Still, co-transfer of T cells into MMC mice resulted in an ... have important roles either during the initiation phase of arthritis or in the perpetuation and exacerbation of the disease after the onset, or they might simply maintain immunity to CII and...
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Báo cáo khoa học: "Pancreatic insulinoma co-existing with gastric GIST in the absence of neurofibromatosis-1" pot
Ngày tải lên :
09/08/2014, 04:21
... an insulinoma in the absence of NF-1 The GIST tumour was only incidentally discovered by the operating surgeon during enucleation of the insulinoma in our case The literature contains only published ... like the initial one in our case, are usually an incidental surgical finding, while large tumours are usually symptomatic In our case, following resection of the insulinoma and the small incidental ... simple excision of the gastric lesion with minimal dissection as was done The other unique message in our case is the observed rapid recurrence of the GIST following the resection of the primary...
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Báo cáo y học: " Effector mechanisms of interleukin-17 in collagen-induced arthritis in the absence of interferon-γ and counteraction by interferon-γ" pot
Ngày tải lên :
09/08/2014, 14:22
... as the percentage of swelling (i.e 100 × the difference between the increase of thickness of the left and the right ears, divided by the thickness of the right ear) at the indicated time points ... of ELR+ CXC chemokines in RA synoviocytes, especially in the presence of TNF-α, highlighting its role in neutrophil recruitment into the joint [49] Furthermore, IL-17 induces the production of ... PBS in the right ear DTH response was calculated as the percentage swelling (the difference between the increase of thickness of the left ear and the right ear, divided by the thickness of the...
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Báo cáo y học: "Candida albicans genome sequence: a platform for genomics in the absence of genetics" potx
Ngày tải lên :
09/08/2014, 20:20
... particular interest to those interested in fungus-host interactions, because many might play roles in the infection process The genome of the closely related species Candida dubliniensis is now being ... genes in the agglutinin-like sequence (ALS) gene family, thought to be involved in adhesion to and interaction with host surfaces [ 15] Nevertheless, over half of the What can be gleaned from the ... SilvaHutner at the Department of Dermatology, Columbia College of Physicians and Surgeons (New York, USA) The original isolate number was 17 75 and the strain is identical with strain NYOH#4 657 in the New...
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Báo cáo y học: "Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2" pptx
Ngày tải lên :
12/08/2014, 18:21
... PAS-staining As shown in Fig 4A, there was minimal PAS staining in the airway epithelium of control mice In contrast, Aspergillus-antigen-treated mice from all three groups showed accumulation of ... JA: IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling J Immunol 2002, 168:2 953 -2962 Hao H, Cohen DA, Jennings CD, Bryson ... development of prominent infiltrates in peribronchovascular spaces and scattered infiltrates in the lung parenchyma (Fig 2A and 2B) The inflammatory infiltrates consisted of numerous eosinophils...
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Bóa cáo y học: "The incidence and outcome of septic shock patients in the absence of early-goal directed therapy" pdf
Ngày tải lên :
12/08/2014, 23:23
... selecting all patients who died in the ED, required care in the ICU (including all patients who died in the ICU), required care in the high dependency unit (HDU; including all patients who died in ... lower These findings are relevant to other institutions considering the application of EGDT and to the powering of future randomized controlled trials It must be borne in mind that this (like the ... started in the ED in 35 (70%) patients Mechanical ventilation was commenced in the ED in 12 (24%) patients Another three patients subsequently required mechanical ventilation in the ICU Of these 52 ...
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Báo cáo y học: "Mechanical ventilation using non-injurious ventilation settings causes lung injury in the absence of pre-existing lung injury in healthy mice" pdf
Ngày tải lên :
13/08/2014, 11:23
... Haarlem, the Netherlands; KMA) Induction of anaesthesia was performed by injecting 7 .5 l/g of induction KMA mix (consisting of 1.26 ml ketamine, 0.2 ml medetomidine and ml atropine) To maintain anaesthesia, ... behind VILI and the contribution of MV to lung injury in the absence of pre-existing lung injury Competing interests The authors declare that they have no competing interests Page of 11 (page number ... either an inspiratory pressure of 10 cmH2O (resulting in VT of about 7 .5 ml/kg; low VT (LVT)) or an inspiratory pressure of 18 cmH2O (resulting in VT of about 15 ml/kg; high VT (HVT)) In C57Bl/6...
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Báo cáo sinh học: "Mapping of a milk production quantitative trait locus to a 1.056 Mb region on bovine chromosome 5 in the Fleckvieh dual purpose cattle breed" pps
Ngày tải lên :
14/08/2014, 13:21
... found on the BTA5 Two hundred and forty of these covered the region most likely containing the QTL in the distal part of BTA5 and were used in the present study We performed SNP genotyping in two ... to insert the newly designed marker (LMU 050 5) with the build option of the CRI-MAP program The resulting final map (Table 1) was used for all the following analyses QTL fine mapping LDL mapping ... an increased frequency of the minor QTL allele Using these subsets, we succeeded in Page 10 of 11 refining the map position of the previously detected QTL for milk production traits on BTA5 to...
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Securities Trading in the Absence of Dealers:Trades, and Quotes on the Tokyo Stock Exchange
Ngày tải lên :
31/10/2014, 12:51
... One hypothesis involves the size of the order It was noted in the discussion of the institutional features of the TSE that the display terminal at a member’s lead, office shows the size of the orders ... article investigates the properties of intraday trades and quotes on the TSE In comparison with most of the worlds other principal equity markets, the TSE is distinctive in the absence of dealers In ... neither order arrives, the warning quote may remain at ¥ 155 0 possibly for the remainder of the trading session) Alternatively, the saitori may successively revise the warning offer down to the...
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Chemical evolution of volatile organic compounds in the outflow of the Mexico City Metropolitan area potx
Ngày tải lên :
28/03/2014, 20:20
... (217) ( 155 ) (273) (1707) T1 24-h 2. 05 500 3001 3206 3688 16 53 6 1092 21 05 6093 53 4 84 57 1407 946 113 75 49 65 46 35 114 52 1 153 81 46 43 1 95 697 624 413 54 2 05 79 75 198 89 57 7 18 75 174 151 58 77 ... altitude upon return into the MCMA The higher mixing ratios of MTBE at the beginning and the end of the flights were obtained during transects over the city In addition to the identification with ... further reduction of the boundary layer height in the morning together with some contribution from traffic and industry during the early morning before the boundary layer has expanded During the...
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Occurrence and fate of semivolatile organic compounds (SVOCs) in the tropical atmosphere
Ngày tải lên :
11/09/2015, 10:15
... 4.18 4 .57 4 .54 5. 22 5. 18 5. 91 5. 86 5. 80 6.00 6.04 6 .50 6 .58 6. 75 N.A 6 .51 6.33 6.79 7.60 7.71 8.87 8.81 10.28 10.29 11.33 11.36 11 .55 12 .54 12.42 12 .58 48.8 15. 7 1.1 6.4 2.6 1.8 6.6 × 10-1 2 .5 × ... better understanding of the distribution of SVOCs among the different compartments in the tropical environment in order to provide more insights into the transport of these selected compounds under ... SVOCs in the Marine Environment of Singapore 34 2.7.1 Usage and Emission of Selected SVOCs in Singapore 34 2.7.2 Occurrence of Selected SVOCs in the Environment of Singapore 35 Chapter...
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Development of new methodologies for the synthesis of enantiomerically enriched compounds
Ngày tải lên :
16/09/2015, 08:30
... Enantioselective Allyl Transfer / Olefin Ring-Closing 159 Metathesis 5. 5 Tandem Enantioselective Allyl Transfer / Olefin Cross 166 Metathesis 5. 6 Enantioselective Synthesis of Syn-2,6-disubstituted-4-halo- ... illustrations for the synthesis of the cis-linear regioisomer Herein, an effective and unusual approach towards the synthesis of enantiomerically cis-linear homoallylic alcohols using commercially ... published their innovation on the Lewis acid mediated reaction of crotyltins with aldehydes that produces the syn-homoallylic alcohols regardless of the geometry of the double bond of the allylic tins...
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Tài liệu Characterization of the Polymorphic Behavior of an Organic Compound Using a Dynamic Thermal and X-ray Powder Diffraction Technique pptx
Ngày tải lên :
14/02/2014, 03:20
... 25 1 25 25 1 25 25 150 25 150 30 75 155 1 85 200 100 end (°C) 1 25 25 1 25 25 150 30 150 30 75 155 1 85 200 100 30 rate (°C/min) –1 –1 –2 –2 10 10 –10 –2 hold (min) 10 10 10 10 0 0 Figure 30 DSC of ... 13 -2 45 24 174 181 231 248 36 14 10 53 38 174 179 231 248 36 190 198 20d 239 250 57 45 22 52 2 25 100 111 194 2 05 16 2 05 218 12 52 26 55 313 99 103 159 166 188 202 14 56 116 56 e 171 1 85 190 201 ... Form I hydrate involved either stirring the Step wetcake in 95/ 5 (v/v) acetone/water at ambient temperature for more than 10 h or heating the Step wetcake in 95/ 5 acetone/water below the reflux temperature...
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