... be of interest to compare the performance of selected lines in other olfactometers, especially those permitting optomotor anemotaxis, the normal mechanism used by Drosophila in responding to distant ... summarised in table The results indicate a bidirectional response to selection for both the males and females Lines selected for unresponsiveness differ from controls in the to 10 generation interval ... (1976, 1978) for geographic strains and chromosome II lines was also odorant specific Selection for ethanol did not result in a change in response to acetaldehyde (and vice-versa for acetaldehyde),...
Ngày tải lên: 09/08/2014, 22:23
... response in patients undergoing PCI, the data for aspirin response in this context remains limited being restricted to retrospective data suggesting a role for poor response to aspirin in PCI patients ... assays for the assessment of aspirin response 1.4 Comparison of methods to assess the response to aspirin The introduction of new point-of-care assays to assess the response to aspirin has rekindled ... pronounced in males than females led early investigators to look into the variation in antiplatelet effects of aspirin (31) Further interest in measuring this variation in response in stroke patients...
Ngày tải lên: 22/12/2014, 21:54
báo cáo hóa học:" Validation of a HLA-A2 tetramer flow cytometric method, IFNgamma real time RT-PCR, and IFNgamma ELISPOT for detection of immunologic response to gp100 and MelanA/MART-1 in melanoma patients" doc
... 10, and 20 μL) was performed and the use of 10 μL was found to be optimal Long term performance of the tetramer was monitored to achieve optimal binding and to assure longitudinal assay performance ... equivalent to 1/8000–1/ 10,000) Studies were also performed using TIL1520 spiked into TIL1143 stained for gp100 and TIL1143 spiked into TIL1520 stained for MART-1 Assay sensitivity was 1/1000 to 1/2000 ... preparation, staining methods, machine setting, gating during acquisition and data analysis Percent CV
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: "Clinically important improvement in the WOMAC and predictor factors for response to non-specific non-steroidal anti-inflammatory drugs in osteoarthritic patients: a prospective study" docx
... predictors in one of the other models, were included to the model and stayed in the model To examine whether disease severity is a predictor for response the WOMAC global baseline score was included ... corticosteroid or intra-articular hyaluronic acid joint injection within weeks before randomization, a known allergy of indomethacin or diclofenac and history of abuse use of alcohol or drug use within year ... Clinically important improvement in the WOMAC and predictor factors for response to non-specific non-steroidal anti-inflammatory drugs in osteoarthritic patients: a...
Ngày tải lên: 21/06/2014, 19:20
Báo cáo y học: "A mathematical model for LH release in response to continuous and pulsatile exposure of gonadotrophs to GnRH" ppt
... Janovick JA, Lin X, Conn PM: Simultaneous and independent visualization of the gonadotropin-releasing hormone receptor and its ligand: evidence for independent processing and recycling in living cells ... of each individual pulse and, as in [1],, α = nM-1 and β = min-1 In response to GnRH, calcium is released from the ER into the cytoplasm with a rate constant ERR and is pumped back into the ER ... released in minute intervals in the original model and the present model in response to continuous administration of nM GnRH In both models there is an initial large pulse of LH released However, in...
Ngày tải lên: 13/08/2014, 22:22
Tài liệu New Jnches Sustainability Issues Working Group An Insider’s Guide to Finance and Accounting in Higher Education docx
... struggling to understand these statistics, speak to your finance director or planning team An Insider’s Guide to Finance and Accounting in Higher Education Costing and pricing Without going into too ... necessary to reflect financing and infrastructure costs An Insider’s Guide to Finance and Accounting in Higher Education Hedging HEIDI Higher Education Information Database for Institutions Internal ... adequate and working This in turn is reported to the principal funding body Ensuring the independence of the audit committee is a key task for the governing body An Insider’s Guide to Finance and...
Ngày tải lên: 18/02/2014, 01:20
Sexual and Reproductive Health, Rights, and Realities and Access to Services for First Nations, Inuit, and Métis in Canada docx
... determine and develop priorities and strategies for exercising their right to development In particular, indigenous peoples have the right to be actively involved in developing and determining ... offered in a culturally safe Sexual and Reproductive Health, Rights, and Realities and Access to Services for First Nations, Inuit, and Métis in Canada way and tailored to the specific needs and interests ... have the right to their traditional medicines and to maintain their health practices, including the conservation of their vital medicinal plants, animals and minerals Indigenous individuals also...
Ngày tải lên: 05/03/2014, 17:20
Báo cáo khoa học: BRCA1 accumulates in the nucleus in response to hypoxia and TRAIL and enhances TRAIL-induced apoptosis in breast cancer cells pdf
... proteins involved in various cellular processes, including inhibition of apoptosis Hypoxia has been reported to inhibit apoptosis induced by tumor necrosis factor-related apoptosisinducing ligand ... selectively induces apoptosis in malignant, but not nonmalignant, cells [16] TRAIL binds to death receptors, DR4 and DR5, and recruits Fas-associated death domain protein to the receptors Caspase-8 ... BRCA1 or induce apoptosis in a cell line expressing mutated BRCA1 The data in Figs and suggest that TRAIL can alter BRCA1 localization and induce apoptosis in breast cancer cells Therefore, we...
Ngày tải lên: 30/03/2014, 03:20
báo cáo hóa học:" A decade of modelling research yields considerable evidence for the importance of concurrency: a response to Sawers and Stillwaggon" potx
... network inference and simulation This group recognized that the existing tools did not allow for the kinds of rich modelling needed for this and other questions of STI epidemiology to be explored in ... Presupposing nefarious intents for those doing so is counterproductive In contrast to Sawers and Stillwaggon, I end with a call to leave open all promising areas Page of of research in trying to solve one ... therein It incorporates observed levels and patterns of concurrency from a Zimbabwe data set [32], including gender asymmetry, and distinguishes between counts of cohabiting and non-cohabiting...
Ngày tải lên: 20/06/2014, 08:20
Báo cáo lâm nghiệp: "Water relations of cork oak (Quercus suber L.) seedlings in response to shading and moderate drought" ppt
... mechanisms to withstand environmental conditions in sun and shade-grown seedlings Osmotic and elastic adjustments are found to help cork oak seedlings to maintain turgor during moderate water stress and ... Values of F statistic and results of fitting the functions for the HL and LL groups are shown in Table III For both light groups, Ψπ100 and Ψπ0 values in seedlings submitted to a moderate water ... and morphological responses to shade and drought in two contrasting ecotypes of Prunus serotina, Tree Physiol 10 (1992) 343–355 [5] Aranda I., Gil L., Pardos J.A., Effects of thinning in a Pinus...
Ngày tải lên: 08/08/2014, 00:22
Báo cáo lâm nghiệp:"Growth and biomass partitioning of Fagus sylvatica L. and Quercus robur L. seedlings in response to shading and small changes in the R/FR-ratio of radiation" pot
... variable, Z1 is for oak and –1 for beech, Z2 is –1 for the shading treatments and for the control, Z3 is –1 for the green net and for the black net Z1Z2, Z1Z3, Z1Z2Z3 refer to interactions between ... petraea and an increasing length growth of these branches with increasing Response of beech and oak to shading 167 Figure Growth components measured on seedlings of oak and beech exposed to full ... Z1 and Z2 for RHG and RGDS in the second part of the growing period as well as in the total period indicates that the difference between the control and the shade treatments in height growth and...
Ngày tải lên: 08/08/2014, 01:21
Báo cáo toán học: "SIMWAL: A structural-functional model simulating single walnut tree growth in response to climate and pruning" docx
... closely, radiation being the main factor driving photosynthesis and consequently tree development in the model In spring C was preferentially incorporated into leaves and new GUs During this period ... and branching order) which are in turn split into growth units (GUs; see figure 2), internodes and nodes bearing a bud and a leaf Each organ is positioned in the 3D space by its coordinates and ... Branching rules for walnut and variability in crown development are taken into account by computing the probability of budburst Pb for each bud j according to the bud position in the tree and GU...
Ngày tải lên: 08/08/2014, 14:22
Báo cáo khoa học: "The behavior of oaks in response to natural and induced exposure to the surfactant ABS" potx
... Variation in and natural selection for air pollution tolerances in trees In: Genetic Effects of Air Pollutants in Forest Tree Populations (Scholz F, Gregorius HR, Rudin D, eds) Springer-Verlag, Berlin, ... considerably shorter in damaged trees than in the ’healthy’ individual tested, but there was no difference in tube length be- germination was containing no lower in tween the windward and leeward sides ... of ABS to the culture reduced germination in all trees The extent of reduction increased with increasing doses, until 0% germination was reached at mg/l for the ’healthy’ tree and mg/l for the...
Ngày tải lên: 08/08/2014, 19:21
Báo cáo khoa học: "Early prediction of response to radiotherapy and androgen-deprivation therapy in prostate cancer by repeated functional MRI: a preclinical study" pptx
... weights, representing the interneuron synapses in the brain Further, the BPNN architecture is divided into three layers; input, hidden and output layers The input layer feeds information into the network, ... training, testing and validating the network showed curve flattening after a few training epochs, this indicated that no overtraining occurred However, if such a model is to be applied on clinical ... sessions, and together with volumes and PSA measurements, these parameters were independently and combined used as inputs to a BPNN in order to explore their feasibility of predicting treatment response...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo y học: "Human meniscus cells express hypoxia inducible factor-1α and increased SOX9 in response to low oxygen tension in cell aggregate culture" ppsx
... from the outer region In order to determine whether these differences in expression in vivo were reflected in different responses inherent in the cells present in inner and outer meniscus, we ... particular interest, because the action of HIF-1α is modulated at the post-translational level Furthermore, HIF-1α has been shown to bind to CREB (cAMPresponse element-binding protein)-binding protein/p300, ... susceptible to transcriptional control by HIF-1α in low oxygen tension [52] We therefore investigated the link between HIF-1α and P4Hα(I) by using the HIF-1α inhibitor YC-1 [53,54] In monolayer...
Ngày tải lên: 09/08/2014, 10:20
báo cáo khoa học: "Individualized therapies in colorectal cancer: KRAS as a marker for response to EGFR-targeted therapy" docx
... has tyrosine kinase activity EGFR binds soluble ligands, including epidermal growth factors (EGFs) and transforming growth factor-alpha, and the ligand/receptor complex then signals the formation ... predictive value of KRAS in determining response to cetuximab-containing regimens may be improved by combining it with other predictive factors [15] determined the KRAS mutation status and mRNA expression ... in combination with standard-regimen irinotecan compared with standard-dose cetuximab for patients with grade 0/1 skin reactions To determine whether dose escalation was also able to induce response...
Ngày tải lên: 10/08/2014, 22:20
báo cáo khoa học: "The grapevine guard cell-related VvMYB60 transcription factor is involved in the regulation of stomatal activity and is differentially expressed in response to ABA and osmotic stress" ppt
... modulates physiological responses in guard cells, leading to the possibility of engineering stomatal conductance in grapevine, reducing water loss and helping this species to tolerate drought under ... stomatal opening and enhanced tolerance to dehydration [10] Guard cell-specific MYB genes are thus focal points in understanding stomatal regulation in plants and represent molecular targets to ... analysis of GUS expression in pVvMYB60:GUS leaves in response to ABA (H) GUS staining of stomata in a control leaf (I), GUS staining of stomata following hours of exposure to 100 μM ABA Galbiati...
Ngày tải lên: 11/08/2014, 11:21
Báo cáo y học: " Mutations in the E2-PePHD region of hepatitis C virus genotype-3a and correlation with response to interferon and ribavirin combination therapy in Pakistani patients" pptx
... domain in breakthrough responders with PePHD domain of genotype made it a more efficient candidate for binding to and inhibiting PKR This leads HCV to persist by evading antiviral activity of interferon ... from PePHD binding to PKR and inhibiting antiviral activity of IFN alpha, other factors might also be involved in establishing the response rates to anti-viral treatment Additional investigations ... treatment response Hepatology 2000, 31(6):1360-1370 Lo S, Lin HH: Variations within hepatitis C virus E2 protein and response to interferon treatment Virus Res 2001, 75(2):107-112 Saito T, Ito T, tto...
Ngày tải lên: 11/08/2014, 21:21
báo cáo khoa học: " PR genes of apple: identification and expression in response to elicitors and inoculation with Erwinia amylovora" doc
... genes related to several model plants, especially, Arabidopsis thaliana [2], and members of the Solanaceae family, including tomato and tobacco [6,7] In order for SAR to develop in these, plants ... protein can account for 1% of the total leaf protein in TMV-infected tissue [9] In cucumber, PR-8 is robustly induced following treatment with SA or the related, but less phytotoxic compound INA ... share sequence similarity to proteins involved in innate immunity in the animal kingdom [16,17] We undertook this study in an attempt to identify markers for the SAR pathway in apple Specifically,...
Ngày tải lên: 12/08/2014, 05:20
Báo cáo khoa học: " Endocrine and Ovarian Changes in Response to the Ram Effect in Medroxyprogesterone Acetate-primed Corriedale Ewes" ppsx
... Endocrine and ovarian changes in response to the ram effect 39 Fig Fourteen ewes were isolated from contact with rams for 30 days and primed for days with an intravaginal sponge containing 60 ... (for review see Walkden-Brown et al 1999) In ewes, the ram effect has been extensively used to induce out-of-season estrus in order to obtain births during autumn (Martin et al 1986) Introducing ... examination, blood samples were collected by jugular venipuncture and allowed to clot for h at room temperature before being 35 centrifuged for 10-20 min, and stored at -20°C until assayed for...
Ngày tải lên: 12/08/2014, 15:21