superficial x ray therapy of hand eczema

... of the structure of AII in solution with the X- ray structure of AII complexed to the Fab131 mAb In Fig 7A, a sequence alignment is represented of the backbone of the conformational ensemble of ... side chains of Val3 and Pro7) (a) with the the X- ray structure of AII in the Fab131–AII complex [30] (b) exclude solvent by filling the cavity The most buried residues of AII are of the central ... between the X- ray structure of AII and the ensemble of 13 AII calculated structures Superposition is based on sequence and structure alignment Residue number range in the X- ray structure of AII Fig...

Ngày tải lên: 20/02/2014, 23:20

... an rmsd of approxi˚ mately 1.6 A from that of MtPpiA, when the Ca atoms are ˚ compared using a cut-off of 3.5 A (with  88% of the Cas matching) This is significantly larger than the rmsd of ˚ 0.05 ... the presence of a hexa-peptide of sequence HAGPIA derived from the HIV capsid protein sequence [14] The expected site for binding the hexa-peptide is indicated using a superposition of the human ... Ramachandran plot [35] Using the parameters of Engh and Huber [36] strongly anisotropic Inspection of a number of criteria at various stages of the solution and refinement (including Rfree, figure of...

Ngày tải lên: 16/03/2014, 18:20

... values of 17% and 22% (Table 1) Electron density was observed for all except residues 1–2 and 308–309 of the complete sequence in both molecules of the asymmetric unit The structure is composed of ... first helices of domains and 2, respectively The EF -hand- like calcium site of domain was described earlier, and tight binding of the ion was shown to contribute to the integrity of the protein ... cut-off of 0.5 A, it is seen that there is a very small (1.5°) difference in their relative orientations A nearly perfect twofold axis (179°) relates the two molecules, ˚ with 750 A2 on domain of...

Ngày tải lên: 23/03/2014, 04:21

... the group of experts, (2) assess the metric properties of the items, (3) reduce the number of questions to a maximum of three per dimension and (4) obtain evidence of the validity of the instrument ... point, the expert panel generated an initial pool of questions about the following aspects of drug treatment of skin conditions of the hand: overall satisfaction, effectiveness, convenience of application, ... properties of the final version Feasibility The results of the factor analysis of the reduced scale (see Table 4) suggested the presence of four to six dimensions The goodness -of- fit test for the maximum...

Ngày tải lên: 12/08/2014, 01:21

... index nor the chest x- ray score of pulmonary edema correlates with markers of oxygenation, severity of illness or PICU length of stay Page of 11 Key messages • Extravascular lung water index measured ... correlate with a chest x- ray score of pulmonary edema • Extravascular lung water in critically ill children does not correlate with parameters of oxygenation • A chest x- ray score of pulmonary edema ... http://ccforum.com/content/14/3/R105 Figure Example of chest x- rays and related variables in four children with the lowest and highest chest x- ray score Page of 11 Lemson et al Critical Care 2010,...

Ngày tải lên: 13/08/2014, 20:22

... http://ccforum.com/content/14/4/430 Page of Table Patient characteristics per patient Diagnosis Length of PICU stay (days) Ventilator days Probability of death PRISM II % 14.0 Near Drowning 19 ... 85 Patient Age Weight number Gender (months) (kg) F 24 Probability of death PIM % Outcome 60 survived F 83 18.0 Reconstruction of pulmonary artery 18 16 survived F 23 14.0 Abdominal surgery 78 ... survived F 4.8 Arterial switch operation 13 10 39 survived F 7.1 Tetrology of Fallot repair 16 14 18 survived F 6.5 Reconstruction of pulmonary artery 2 survived M 4.4 VSD repair 13 26 survived 10 M...

Ngày tải lên: 13/08/2014, 21:21

... medium The surface brightness of an extended source S X is defined as the flux ( fX ) per solid angle (Ω) Hence, fX Ω (2.16) LX Ω 4πD2L (2.17) SX = =⇒ S X = =⇒ S X = =⇒ S X = A dA Ω dV V (2.18) Ω ... the analysis of spectra of low-mass galaxy groups X- ray data of galaxy clusters gives an excellent insight into the density and temperature distribution of the cluster In the next two subsections ... brightness profile of the ICM The density of the X- ray emitting gas is closely related to the X- ray surface brightness of the galaxy cluster which is demonstrated here Starting from the radial galaxy density...

Ngày tải lên: 26/11/2015, 10:18

... section of the phantom shows the maximal fluctuation of the CBCT numbers is ± 35 Hounsfield unit (HU), which translates to a fluctuation of approximately 1% in electron density values Conversion of ... Descovich M, Xia P, Pouliot J: Dose calculation using megavoltage cone-beam CT Int J Radiat Oncol Biol Phys 2007, 67:1201-10 Ding GX, Duggan DM, Coffey CW: Characteristics of kilovoltage x- ray beams ... differences of the dose to tumor and some normal tissues were within 1% and 3.2%, respectively The difference of maximal dose in tumor is 0.49% and in normal structures are 3.15% Five out of six patients...

Ngày tải lên: 09/08/2014, 08:23

... diagnosis using scattered X- rays J Synchrotron Rad 2000; 7: 348-352 Malden CH, Speller RD, et al A CdZnTe array for the detection of explosives in baggage by energy dispersive X- ray diffraction signatures ... it is expected different peak positions will exist for carcinoma and fibrocystic changes Our results confirmed this expectation The peak position of fibrocystic change was close to that of carcinoma ... Keyrilainen et al Conclusion Measurements of coherently scattered X- ray photons can be used to identify breast disease In this study using diffraction profiles from EDXRD, distinct peak positions were...

Ngày tải lên: 02/11/2012, 11:08

... II melt of Form II Form I to Form II melt of Form II loss of water melt of Form I Form I to Form II melt of Form II loss of water melt of Form III melt of Form VI loss of water melt of amorphous ... Figure 30 DSC of mixture of hydrated Forms I and IV (sample 8) Figure 31 DSC of mixture of Form III monohydrate and Form IV hydrate (sample 56) Figure 32 Superimposed XRPD of mixture of Form III ... loss of water melt of Form III? loss of water melt of Form III Form I to Form II melt of Form II loss of water melt of Form III Form I to Form II melt of Form II Form I to Form II melt of Form...

Ngày tải lên: 14/02/2014, 03:20

... pantoate-bound form of nPS using X- ray crystallography, as described below A Solution and refinement of the structure using X- ray crystallography B The crystal structure of the pantoate–nPS complex was solved ... this stretch of residues was therefore not rebuilt X- ray crystallographic structure of nPS bound to pantoate Fig The absolute value of deviation in chemical shift (p.p.m.) of residues of nPS upon ... consists of two water molecules The backbone carbonyl oxygen of Phe56 is also hydrogenbonded to the O4 atom of pantoate via one of the water molecules in the same network The phenolic oxygen of Tyr71...

Ngày tải lên: 16/02/2014, 09:20

... crystal structures of these Ec-RNase HI variants, the position of His124, which corresponds to His126 of So-RNase HI, varies for different proteins, because of the intrinsic flexibility of the loop containing ... Destabilization mechanism of So-RNase HI A combination of the six thermostabilizing mutations increases the stability of So-RNase HI by 28.8 °C in Tm and 27.0 kJÆmol)1 in DG(H2O) Five of the six substituted ... the aIII and aIV Fig Stereoview of the three-dimensional structure of 6·-RNase HI The structure of molecule D of 6·-RNase HI (gold) is superimposed on the structure of the wild-type protein (green)...

Ngày tải lên: 18/02/2014, 13:20

... in the X- ray structures of CBM4 and CBM17 complexed with cellopentaose and cellohexaose, respectively [13,23] The involvement of the tyrosine residues in the stabilization of the complex cannot ... relaxation) of cellohexaose resonances upon addition of CtCBM11 In general, a progressive line broadening of all the cellohexaose protons was observed during titration with increasing amounts of ... Fig Line broadening studies (I) Spectral assignment of 1H NMR cellohexaose resonances (II–IV) Series of spectral regions of a solution of cellohexaose 0.787 mM in D2O, corresponding to protons aa1,...

Ngày tải lên: 18/02/2014, 17:20

... concentration range of 30–150 lM (1.3–6.5 mgÆmL)1), 90 lL of arrestin solution was mixed with 10 lL of 10 mM peptide solution to yield a final peptide concentration of mM For higher concentrations of arrestin ... Determination of binding constants from forward scattering The intensity of Ôforward scatteringÕ, or I(0), is the X- ray solution scattering that is parallel to the incident beam, and was determined by extrapolation ... Because of the changing oligomeric state of arrestin in these experiments, Guinier analysis was preferred over the use of the distance distribution function, which requires a prior estimation of the...

Ngày tải lên: 22/02/2014, 07:20

... states of the CTXS-Xyl2-Me complex were not detected with [S-Xyl2-Me]initial ẳ 5200 lM) Protein (modications) Inhibitor Mexp (Da)a TRX I (none) None S-Xyl2-Me S-Xyl3-Me S-Xyl4-Me S-Xyl5-Me None S-Xyl2-Me ... calorimetry of both domains decreased in the series b-d-xylohexaose (Xyl6) > b-d-xylopentaose (Xyl5) > b-d-xylotetraose (Xyl4) > b-d-xylotriose (Xyl3), with no detectable afnity for b-d-xylobiose (Xyl2), ... the expected m z for any charge state of CTXS-Xyl2-Me complex were not detected within [S-Xyl2-Me]initial ẳ 5200 lM) Protein Inhibitor Ka ã 10)3 (M)1) TRX I S-Xyl2-Me S-Xyl3-Me S-Xyl4-Me S-Xyl5-Me...

Ngày tải lên: 07/03/2014, 17:20

... concentrations of % lm were used Peroxidase activity was assayed using hydrogen peroxide and guaiacol (O-methoxyphenol, Sigma) The synthesis of the fourfold oxidized product of guiacol, 3,3¢-dimethoxy-4,4¢-biphenoquinone ... R Worrall et al X- ray and unfolding studies of cyt c-550 Fig Close up of the heme binding pocket of (A) wt and (B) the M100K(rt) variant of ferricyt c-550, with the positions of the buried water ... unfolding of the M100K variant involves the breaking of the Lys-Nf-iron bond coupled with the dynamic process of ligand exchange It thus seems likely that the mechanism of release of the axial ligand...

Ngày tải lên: 07/03/2014, 17:20

... Foundation of China We are grateful to Prof Li-Wen Niu, Prof Mai-Kun Teng and Dr Xue-Yong Zhu of the University of Science and Technology of China for their support and help with the X- ray data ... hydroxyl group However, the crystal structure of the Phe35fiTyr mutant shows that the ˚ hydroxyl oxygen atom of the side chain of Tyr35 is 3.21 A away from the atom CHB of the pyrrole group of the ... conformation of this residue The shift of the Ca atom of Tyr35 of the Phe35fiTyr mutant from that of Phe35 of the ˚ wild-type cyt b5 is 0.21 A, within the error limit The side chain of Tyr35 of the...

Ngày tải lên: 08/03/2014, 10:20

... Biochem 269) are grouped in a superfamily of metzincin which exhibits some typical structural features, such as the Met-turn and active-site consensus HExxHxxGxxH sequence [15–17] Some organisms and ... carbonyl oxygen of Asn107 (c) The C-terminal carbonyl oxygens of these residues are hydrogen-bonded to the N-terminal nitrogen of Ile109 In addition, the side chain of Lys residue also contacts extensively ... potencies of pEWN and pEWK (Table 3) Structural comparison of pENW-(TM-3) with the peptidic inhibitor-complexes of atrolysin C, TACE and HNC Fig Diagram of the active-site structure of TM-3 complexed...

Ngày tải lên: 08/03/2014, 23:20

... complexes with phospholipids that have the properties of a quasicrystalline phase [26,27] We have undertaken an examination of the phase behaviour of ternary mixtures containing representatives of ... changes observed in the SAXS ⁄ WAXS profiles are consistent with a progressive replacement of a gel phase of brainSM and the disappearance of a small proportion of a coexisting highly disordered ... concluded from analysis of the behaviour of this ternary mixture that the properties of the major constituent of the mixture, namely, long N-acyl chain molecular species of sphingomyelin, tend...

Ngày tải lên: 15/03/2014, 23:20

... the binding of the thiol sulfur of HS-CoM to the zinc atom of MtaA in a way that it replaces one of the nonsulfur ligands, possibly the oxygen of coordinated H2O or hydroxide EXAFS of two MtaA ... EXAFS oscillations of Fig Fourier transforms (FT) of k3-weighted EXAFS spectra of wildtype MtaA and of two MtaA mutants (Cys239 Ala, His237 Ala) in the absence and presence of coenzyme M Experimental ... ligated to the zinc of MtaA increases upon formation of the MtaAcoenzyme M complex explainable by ligation of the thiol sulfur of coenzyme M to the active-site zinc We simulated the experimental spectra...

Ngày tải lên: 17/03/2014, 23:20