... maneuvers can open and maintain open ≥ 95% of the lung This required the use of high peak airway pressure (40 to 60 cmH2O) with high PEEP levels (25 to 45 cmH2O) and the careful selection of the optimal ... PN: Lung recruitment and lung volume maintenance: A strategy for improving oxygenation and preventing lung injury during both conventional mechanical ventilation and high- frequency oscillation ... hemodynamically stable and have no indication of existent barotrauma or an increased likelihood of developing barotrauma Post-recruitment, the key to sustaining the lung open is the identification of the optimal...
Ngày tải lên: 13/08/2014, 03:20
... of the active species [76] Further support in favour of the idea of the involvement of a high- valent iron-oxene in P450 catalysis came from experiments with metalloporphyrin models [5,6,77] Of ... discounted in view of the high selectivity of DNA strand breakage [239] Also, density functional theory (DFT) calculations of the electronic structure of an optimized geometric model of activated BLM ... Roles of proximal ligand in heme proteins: replacement of proximal histidine of human myoglobin with cysteine and tyrosine by sitedirected mutagenesis as models for P-450, chloroperoxidase, and...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot
... form of b strand [18] The positive bands at » 1675 cm)1 in the amide I region of the ROA spectra of b- and j-casein, which originate mainly in the peptide C O stretch, are characteristic of disordered ... spectra of all these proteins are very similar to those of disordered poly(Lglutamic acid) at high pH and poly(L-lysine) at low pH [18,19] Accordingly, the ROA spectra of disordered poly(Llysine) and ... types of loops and turns A negative ROA band in the region » 1238±1253 cm)1 appears to be a reliable signature of b strand, individually or within b sheet, so the well-de®ned negative band at...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo khoa học: High resolution structure and catalysis of O-acetylserine sulfhydrylase isozyme B from Escherichia coli pot
... to PLP and not mobile (Fig 5), although it participates in the induced fit (Fig 4) The mobility distributions of CysM(K268A), wildtype CysM and CysM(salmo), and those of subunits B and D of CysM(RKE), ... defines the thiol position of TNB to a small region above the plane of the acrylate double bond As a result of this constraint and of the spacious active center pocket of CysM, TNB was placed rather ... into an average of the closely related subunits B and D and the equally well-related subunits A and C observed asymmetry should reflect a general property of CysM The asymmetry of CysM(RKE) is...
Ngày tải lên: 07/03/2014, 05:20
SITUATION MODELS AND LEVELS OF COHERENCE: Toward a Definition of Comprehension potx
... SITUATION MODELS AND LEVELS OF COHERENCE Toward a Definition of Comprehension SITUATION MODELS AND LEVELS OF COHERENCE Toward a Definition of Comprehension Isabelle Tapiero University of Lyon University ... Coherence: Situation Models as Retrieval Structures 140 PART IV: CONTRIBUTION OF THE READER’S KNOWLEDGE AND THE MULTIDIMENSIONAL ASPECT OF SITUATION MODELS: IMPORTANCE OF CAUSALITY AND EMOTION 149 ... understanding comprehension Nevertheless, more rigorous, complete models of comprehension processes that satisfy strict standards of formal modeling are needed for the future development of text and...
Ngày tải lên: 24/03/2014, 02:20
high resolution separation and analysis of biological macromolecules, part a
... the analysis of enzymatically derived mixtures of peptides and also for the analysis of synthetically derived peptides An example of the high- resolution analysis of a tryptic digest of bovine growth ... time of a nonretained solute The development of high resolution separations of peptides and proteins involves the separation of sample components through manipulation of both retention times and ... reversed-phase ligand is also a crucial step for the full experimental validation of the predictions of the solvophobic model and also to advance our understanding of the mechanism of peptide and protein...
Ngày tải lên: 11/04/2014, 09:46
high resolution separation and analysis of biological macromolecules, part b
... elution time of Mb, cyanogen bromide fragments of Mb and the live synthetic peptide standards Peptide standards 1, 2.3, 4, and contain 10, 20, 30, 40, and 50 residues, respectively, and their sequences ... Fig 1, the standards have been employed to illustrate nonideal and ideal SEC behavior on a silica-based column Figure shows elution profiles of peptide standards 1,2, and (10, 20, and 50 residues, ... sequences of standards 1, 2, and (10, 20, and 50 residues and + 1, +2, and +5 net charge, respectively) are shown in Table The arrows denote the elution time for the total permeation volume of Ihe...
Ngày tải lên: 11/04/2014, 09:46
thomas and patnaik-serial correlation in high-frequency data and the link with liquidity
... horizon of a day, we may observe agents taking time to react as patterns of forecastability in intra-day high- frequency data For example, one class of models explaining the behaviour of intra-day ... issue of the frequency at which to analyse the data How to concatenate returns across days The problem of higher volumes/volatility at the start and at the end of every trading day 2.1 Choice of frequency ... construct the spread and the impact cost of a trade size of Rs.10,000 at each of these times for each of the stocks We use the average impact cost as a measure of intra-day liquidity of the stocks We...
Ngày tải lên: 24/04/2014, 00:23
shillor m., sofonea m., telega j.j. models and analysis of quasistatic contact. variational methods (lnp 655, springer, 2004)(isbn 3540229159)(272s)
... the motion of tectonic plates and, in particular, on earthquakes The engineering literature deals with many aspects and facets of the functioning and operation of machines, mechanisms and structures ... questions of optimal control and of system parameter identification can be addressed These are of considerable theoretical and applied interest Moreover, optimal M Shillor, M Sofonea, J.J Telega: Models ... Rochdi and Sofonea [30] and Han and Sofonea [31], respectively Although it is customary in engineering and certain mathematical publications to consider the normal compliance as an approximation of...
Ngày tải lên: 24/04/2014, 16:49
SITUATION MODELS AND LEVELS OF COHERENCE pptx
... SITUATION MODELS AND LEVELS OF COHERENCE Toward a Definition of Comprehension SITUATION MODELS AND LEVELS OF COHERENCE Toward a Definition of Comprehension Isabelle Tapiero University of Lyon University ... Coherence: Situation Models as Retrieval Structures 140 PART IV: CONTRIBUTION OF THE READER’S KNOWLEDGE AND THE MULTIDIMENSIONAL ASPECT OF SITUATION MODELS: IMPORTANCE OF CAUSALITY AND EMOTION 149 ... understanding comprehension Nevertheless, more rigorous, complete models of comprehension processes that satisfy strict standards of formal modeling are needed for the future development of text and...
Ngày tải lên: 28/06/2014, 21:20
Báo cáo y học: "High resolution discovery and confirmation of copy number variants in 90 Yoruba Nigerians" pdf
... RR and GF conceived the experiments and designed the genome-scan arrays HM and GF designed the typing array PW and GF prepared samples and hybridized the arrays PW, GF, and HM ran PCRs HM and ... matches The number of observed or reported events in the common Yoruba, and the percentage of these events that were matched and compared, give an indication of the extent of missed events in ... McCarroll et al [14] and Wang et al [15] studies, provided an assessment of false-positive and false-negative rates of event detection Although slightly higher, the specificity of event detection...
Ngày tải lên: 09/08/2014, 20:20
Báo cáo y học: " Correction: Frequency, course and correlates of alcohol use from adolescence to young adulthood in a Swiss community survey" ppt
... Correction: Frequency, course and correlates of alcohol use from adolescence to young adulthood in a Swiss community survey BMC Psychiatry 2010 10:15 Submit your next manuscript to BioMed Central and ... presentation of the figure might have caused Received: December 2009 Accepted: 18 February 2010 Published: 18 February 2010 References Steinhausen H-C, Eschmann S, Heimgartner A, Winkler Metzke C: Frequency, ... References Steinhausen H-C, Eschmann S, Heimgartner A, Winkler Metzke C: Frequency, course and correlates of alcohol use from adolescence to young adulthood in a Swiss community survey BMC Psychiatry...
Ngày tải lên: 11/08/2014, 16:22
báo cáo khoa học: " Frequency, type, and distribution of EST-SSRs from three genotypes of Lolium perenne, and their conservation across orthologous sequences of Festuca arundinacea, Brachypodium distachyon, and Oryza sativa" ppt
... NV#20F1-39, and F6 from three different genotypes Random sequencing of cDNA libraries leads to a high proportion of redundant ESTs In this study, both the redundant and non-redundant dataset of EST-SSRs ... EST-SSRs but only in 1.4% and 1.2% of the respective EST-SSRs in the genotypes NV#20F1-30 and NV#20F1-39 In silico analysis of allelic and genotypic SSR motif polymorphisms A total of 521 contigs containing ... NV#20F1-30, NV#20F1-39, and F6, and for the combined dataset NV#20F1-30 Total number of sequences examined: Total size of examined sequences (bp): Total number of identified SSRs: Number of SSR containing...
Ngày tải lên: 12/08/2014, 05:20
Báo cáo y học: "Frequency, stability and differentiation of self-reported school fear and truancy in a community sample" doc
... school grades, and the types of school and formed the basis of the Zurich Epidemiological Study of Child and Adolescent Psychopathology (ZESCAP) A full description of details of the sampling ... Frequency and Stability of School Absenteeism The frequency of school fear was 6.9% at time and 3.6% at time The stability of school fear is shown in figure The number of subjects showing this behaviour ... fear and truancy across three years of time in a large community survey, and (2) the identification of differential features of these two forms of school absenteeism with respect to emotional and...
Ngày tải lên: 13/08/2014, 18:21
Báo cáo y học: "Application of methods of identifying receptor binding models and analysis of parameters" potx
... error and statistical criteria in the design and analysis of experiments for discrimination between rival kinetic models Metods Enzymol 1982, 87:370-390 Gurevich KG: Definition of equilibrium, and ... binding parameters and for analysis of non-equilibrium binding Regression methods can be found for the measurement of ligand-receptor interaction constants [11] As a matter of fact, these procedures ... (7) Numerical solution of equations (5–7) was carried out to determine [RL]u Random error assuming the normal distribution law was superimposed on the magnitude of [RL]u, and was calculated at...
Ngày tải lên: 13/08/2014, 22:22
fracture mechanics of concrete concepts, models and determination of material properties
... crack band model, nonlocal strain-softening models, etc.) are described and random particle simulation o f aggregate microstructure is discussed The principles o f implementation of these models ... safety and economy o f design, but also pave the way for safer and more efficient use of high- performance concretes and permit design extrapolations beyond the range o f previous experiments and ... humidity and temperature, as well as the effect o f cyclic loading Chapter is devoted t o the effect of reinforcing bars and their bond slip on fracture propagation, and t o fracture of fiber-reinforced...
Ngày tải lên: 24/10/2014, 21:58
Modelling, simulation and behaviour of sloshing liquid tank ship coupled system
... OF DOCTOR OF PHILOSOPHY DEPARTMENT OF CIVIL ENGINEERING NATIONAL UNIVERSITY OF SINGAPORE 2008 To my parents, Acknowledgements First of all, I would like to thank my supervisors, Associate Professor ... Effect of number of containers on the moving ship 113 5.5.2 Effect of coupled interaction on responses of containers 118 iv 5.5.3 Effect of location of containers 123 5.5.4 Effect of liquid ... Mitigation of liquid sloshing using baffles 161 6.4.1 Effect of location of single baffle 162 6.4.2 Effect of size of single baffle 166 6.4.3 Effect of thickness of single baffle...
Ngày tải lên: 14/09/2015, 14:01
Measurement and behaviour of heavy metals in the marine environment of singapore
... and healing of wound and the sense of taste and appetite Chromium is necessary for the proper utilization of sugars and other carbohydrates by optimizing the production and effects of insulin ... 2002): Mining and processing ores: Digging a mine, removing ore from it, and extraction and processing of the minerals may destroy habitats, farmland, and homes; produce soil erosion; and pollute ... are one of the major anthropogenic sources of specific heavy metal pollution depending on the profile of a specific industry Agricultural runoff: The metal content of agriculture runoff originates...
Ngày tải lên: 10/11/2015, 12:34
Báo cáo khoa học: "Efficient Unsupervised Discovery of Word Categories Using Symmetric Patterns and High Frequency Words" ppt
... fragments ‘book and newspaper’, ‘newspaper and book’, ‘book and note’, ‘note and book’ and ‘note and newspaper’ In this case the three words are assigned to a category Note that a pair of nodes connected ... is fully unsupervised, requiring no corpus annotation or manually provided patterns or words Pattern candidates are discovered using meta-patterns of high frequency and content words, and symmetric ... Discovery of Patterns Our first step is the discovery of patterns that are useful for lexical category acquisition We use two main stages: discovery of pattern candidates, and identification of the...
Ngày tải lên: 23/03/2014, 18:20
báo cáo hóa học: " The effects of high frequency subthalamic stimulation on balance performance and fear of falling in patients with Parkinson''''s disease" docx
... Journal of NeuroEngineering and Rehabilitation 2009, 6:13 Background Postural instability is one of the cardinal symptoms of Parkinson's disease (PD), and persons with PD run an increased risk of ... activities, e.g walking and turning [3], and it is common to experience near falls and a fear of falling [2,4,5] Contributing factors to falls are numerous and affect both voluntary and reflexive movements ... posturography tests have the advantages of allowing a standardized and reproducible procedure of using external balance perturbations and a quantification of the postural responses Posturographic...
Ngày tải lên: 19/06/2014, 08:20