study laboratory experiments and meta analysis

... oils’’ ‘‘(1) AND (2)’’ OR ‘‘(1) AND (3)’’ OR ‘‘(1) AND (4)’’ OR ‘‘(1) AND (5)’’ 0174 January 2007 | Volume | Issue | e20 Tobacco and Biomass Smoke and TB Figure Flow Diagram of Study Steps and Exclusions ... Extraction and Quality Assessment For every eligible study, we collected detailed information on year and country of study, study design, study population, sample size, choice of controls, definition and ... Peto, N Shetty, and M Tipayamongkholgul) of this study for helping with data collection Author contributions HHL, ME, and MM conceived of the study and devised the search and analysis strategies...

Ngày tải lên: 15/03/2014, 20:20

... sensitivity and specificity) and because substantial between -study heterogeneity is common, meta- analysis of diagnostic accuracy requires different and more complex methods than traditional meta- analytic ... hierarchical regression approach to metaanalysis of diagnostic test accuracy evaluations Stat Med 2001; 20: 2865–84 31 Harbord R, Whiting P Metandi: meta- analysis of diagnostic accuracy using ... random effects regression and HSROC analyses, we used the user-written ‘‘metandi’’ program for Stata [31] Data Synthesis and Meta- Analysis Multiple sources of heterogeneity frequently exist when summarizing...

Ngày tải lên: 22/03/2014, 18:20

... transplant) and 2007 to evaluate the effectiveness of pretransplant tuberculosis skin testing and LTBI treatment, the prevalence and outcome of MTB infections, and the effects of patient factors and ... vaccinations and tuberculin skin tests JAMA 1985;253:3438-3439 140 Menzies D, Pai M, Comstock G Meta- analysis: new tests for the diagnosis of latent tuberculosis infection: areas of uncertainty and recommendations ... 926 had a TST placed (31%), and 124 were positive (13% of those tested) Seven studies evaluated the efficacy of isoniazid LTBI treatment in liver transplant candidates and recipients with a known...

Ngày tải lên: 29/03/2014, 03:20

... for the integrity of the analysis DW, UM and MVG extracted and analysed the data All authors collaborated in interpreting the data and writing the manuscript and read and approved the final manuscript ... performed metaregression analysis with the proportion of never-smokers and with the years of asbestos-exposed occupation All calculations were performed with the software Comprehensive Meta- Analysis ... Medicine and Toxicology 2011, 6:21 http://www.occup-med.com/content/6/1/21 Page of 16 We have conducted a systematic review and a metaanalysis of the literature with the aim of identifying and quantifying...

Ngày tải lên: 20/06/2014, 00:20

... parental death and 5.9% (n = 838) in participants who reported both parents alive Figure shows weighted ORs and 95% CIs for HIV prevalence in each study Results from a random-effects meta- analysis ... geographic areas Seventh, one study accounted for the majority of participants included in this meta- analysis [34] However, after omitting this study from the meta- analysis, the overall effect ... orphans and double orphans These findings are summarized in Table 3, along with the number and gender of participants for each study Table STI and pregnancy among orphans versus non-orphans Study...

Ngày tải lên: 20/06/2014, 08:20

... This meta- analysis shows that the fewer Table Summary of the meta- analyses Comparison Summary effect 95% CI p-value for heterogeneity test Model used

Ngày tải lên: 20/06/2014, 15:20

... of an influence analysis in which the metaanalysis is re-estimated omitting each study in turn Rerunning the analysis without the study by Mathias and Kent [32] increased the standardised mean ... of this study on the overall meta- analysis, the meta- analysis was repeated excluding one study at a time to ensure that the results were not biased by a single outlier Rerunning the analysis ... (Stata, College Station, TX, USA) using the user-contributed commands for meta- analyses: ‘metan’ [19], ‘metainf’ [20], ‘metabias’ [21] and ‘metatrim’ [22] In order to estimate whether the IQ of those...

Ngày tải lên: 09/08/2014, 01:21

... with planning the study, data extraction, analysis, and preparing the manuscript; SD with data extraction, analysis, and writing; GTM with planning, data extraction, analysis, and writing the manuscript; ... intention-to-treat (number of patients randomised and receiving at least one dose of trial drug) analysis Homogeneity tests and funnel plots, though commonly used in meta- analysis, were not used here because ... arthritis Patients and study personnel were blinded to the identification of medication throughout the study, and if randomisation blind was broken, the patient was removed from the study Discontinuation...

Ngày tải lên: 09/08/2014, 06:22

Ngày tải lên: 09/08/2014, 07:20

... antibody therapy in rheumatoid arthritis and the risk of serious infections and malignancies Systemic review and meta- analysis of rare harmful effects in randomized controlled trials JAMA 2006, ... effects in randomized controlled trials JAMA 2006, 295:2275-2286 Stern R, Wolfe F: Infliximab dose and clinical status: results of studies in 1642 patients with rheumatoid arthritis J Rheumatol 2004,...

Ngày tải lên: 09/08/2014, 08:22

... concerning MMF in lupus nephritis from randomised trials and observational studies Materials and methods QUOROM (quality of reporting of meta- analyses) and MOOSE (meta- analysis of observational studies ... to whether they were randomised, double-blind, and accounted for withdrawals or drop-outs and to whether the methods of randomisation and double-blinding were described and appropriate No scoring ... planning the study, data extraction, and analysis, and preparing a manuscript SD was involved with data extraction, analysis, and writing Both authors read and approved the final manuscript Page...

Ngày tải lên: 09/08/2014, 08:23

... study and participated in its design, coordination, data acquisition and analysis, and in manuscript preparation CPW and ELM participated in the study design, data acquisition and analysis, and ... the overall meta- analysis results in the randomized clinical trials Comparison of (a) the forced vital capacity (FVC) and (b) the diffusing overall meta- analysis results in the randomized clinical ... randomized controlled trials on this topic is a limitation, and larger randomized controlled trials are needed to better understand the role of CYC in the care of these patients In our meta- analysis, ...

Ngày tải lên: 09/08/2014, 13:22

... review and meta- analysis of randomized trials Mayo Clinic Proc 2008, 83(4):418-430 20 Pittas AG, Siegel RD, Lau J: Insulin therapy for critically ill hospitalized patients: a meta- analysis of randomized ... significantly weighted by one study, the Lazar (2004) study, and the times spent in CCU/ ICU vary dramatically between groups in a meta- analysis [14,16-18] (n = 582), and the results are shown in ... data as a median and range, and asked if they could provide their data as means and standard deviations, unfortunately, these data were not available Therefore, we conducted a meta- analysis of the...

Ngày tải lên: 10/08/2014, 09:23

... all diagnostic imaging features associated with CPHP and evaluate study findings by meta- analysis where appropriate Methods Search strategy and eligibility criteria A systematic review was conducted ... was greater than 50% and the Chi2 test indicated statistically significant heterogeneity (P < 0.1) Meta- analysis by the randomeffect method incorporates heterogeneity into the analysis, resulting ... groups may be overestimated by meta- analysis [18] Eligibility criteria, quality assessment procedures and methods of data analysis were specified prospectively and outlined in an unpublished...

Ngày tải lên: 10/08/2014, 21:24

... Wolf and colleagues [8] used a modified Heidelberg foot model where the distance and rotations between the calcaneus and st and th metatarsal head markers were used to Table Description and methodological ... [8,23] Wegener and co-investigators [23] used a foot model of rearfoot (three calcaneal markers), forefoot (markers located at the navicular, th metatarsal head and st metatarsal head) and hallux ... than 25%, a random effects model analysis was used Where I2 was less than 25%, a fixed-effects model was used When necessary, reported measures were converted to standard units, and standard errors...

Ngày tải lên: 10/08/2014, 21:24

... (France and Tunisia) Within the meta- analysis, this study was treated as two separate studies Of the remaining six studies the country of origin of two studies was USA [24,25] and there was one study ... revised all versions of the manuscript KN and DG contributed to study selection, study quality assessments and data extraction MM contributed to study selection, study quality assessments, interpreting ... medication and we could not conduct moderator analysis exploring the extent of its effects Despite some similar labels, it should be kept in mind while interpreting the meta- analysis that the rating and...

Ngày tải lên: 11/08/2014, 15:22

... with “nicotine” AND “smoking” AND “gum OR Patch OR spray OR inhalers OR Tablet OR lozenge” AND “random*” 280 abstacts were obtained when using “bupropion” and “smoking” and “random” and “clinical ... http://www.harmreductionjournal.com/content/6/1/25 Figure Random2effects meta- analysis of all NRT trials combined versus all inert controls at weeks Random effects meta- analysis of all NRT trials combined versus ... Jorenby DE 2.77 (1.79, 4.2 Figure Random4effects meta- analysis of smoking cessation with bupropion versus controls at 4-weeks post-TQD Random effects meta- analysis of smoking cessation with bupropion...

Ngày tải lên: 11/08/2014, 18:20

... http://respiratory-research.com/content/11/1/12 Authors’ contributions CJR and DDS conceived the study design CJR and SN performed the search and data abstraction All authors participated in data analysis and interpretation All authors ... [7,8] A meta- analysis by Macchia et al in 2007 included some patients with non-PAH pulmonary hypertension and the results of several trials have been reported since this publication [7] A meta- analysis ... abstraction, and methodologic grading were performed independently by two authors (CJR and SN) using a predefined standardized data abstraction form All discrepancies were resolved by iteration and consensus...

Ngày tải lên: 12/08/2014, 11:20

... inverse variance of each study IV, inverse variance (method); SD, standard deviation; Std mean difference, standardised mean differences; random, random effects model; SD, standard deviation; total, ... inverse variance of each study IV, inverse variance (method); SD, standard deviation; Std mean difference, standardised mean differences; random, random effects model; SD, standard deviation; total, ... (internal and external validity) of the randomised controlled trials' analysis Author, year Adequate randomisation Adequate allocation concealment Blinding of assessor Intention-to-treat analysis...

Ngày tải lên: 12/08/2014, 12:20

... original Strachan and Cook systematic review and meta- analysis [3] was repeated in the current study and included a comprehensive literature search of MEDLINE (1997 to November 2010) and EMBASE (1997 ... studies included in updated meta- analysis 31 studies included from Strachan and Cook Review 60 studies included in updated meta- analysis Figure Flow diagram of included and excluded studies Jones ... since the original systematic review was published however, and the updated systematic review and meta- analysis described in the present study combines data from 31 of the studies used in the original...

Ngày tải lên: 12/08/2014, 13:22