... metal– thiolate clusters; protein structure; zinc Correspondence P. Faller, CNRS, LCC 205, route de Narbonne, 31 077 Toulouse, France Fax: +33 5 61 55 30 03 Tel: +33 5 61 33 31 62 E-mail: peter.faller@lcc-toulouse.fr *This ... Zn 4 cluster of Cu 4 Zn 4 MT -3 [32 ] formation of Cu 4 Zn 3 MT -3 with disulfide Not studied K d of Cu(I) K d estimated to be 1 · 10 )19 M Stronger Cu(I) affinity? [35 ] Weaker Cu(I) affinity? [35 ] Cu(II) ... with human apo-T3 and its separate domains reproduced closely the features of the isolated native MT3 forms (bovine, equine) [32 ,33 ]. Moreover, titration experiments of Cu(I) to apo-T3 (or to apo- a-...
Ngày tải lên: 16/02/2014, 15:20
Tài liệu Báo cáo khoa học: The crystal structure of human a-amino-b-carboxymuconatee-semialdehyde decarboxylase in complex with 1,3-dihydroxyacetonephosphate suggests a regulatory link between NAD synthesis and glycolysis ppt
... at a resolution of 2.0 A ˚ . The monomer present in the asymmetric unit contains 33 2 residues out of 33 6, one zinc ion, one DHAP molecule, one glyc- erol molecule and a total of 216 solvent molecules. ... significant depletion of the NAD+ level [31 ,33 ]. We propose that hACMSD inhi- bition could result in alleviation of cerebral malaria symptoms by controlling both PA and NAD levels [7 ,34 36 ]. Recently, ... 2.0 Observations 63 794 Unique reflections 24 525 Rmerge 0.124 Multiplicity 2.6 Completeness (%) 94 Number of protein atoms 2 635 Number of solvent molecules 216 Number of DHAP ⁄ Zn atoms 10 ⁄ 1 Number of glycerol...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Critical Miscellanies (Vol. 3 of 3) Essay 10: Auguste Comte ppt
... COMTE. PAGE Introduction 33 7 Influence of Saint Simon 34 0 Marriage 34 3 Serious illness 34 5 Official work 34 7 Completion of Positive Philosophy 34 9 J. S. Mill 35 0 Question of Subsidy 35 2 Money 35 3 Literary method 35 4 Hygiène ... 35 4 Hygiène cérébrale 35 6 Madame de Vaux 35 6 Positive Polity 35 8 Death 35 9 Comte's philosophic consistency 36 0 Early writings 36 1 Law of the Three States 36 3 Classification of sciences 36 6 Miscellanies ... MISCELLANIES (3 OF 3) *** ***** This file should be named 29 033 -8.txt or 29 033 -8.zip ***** This and all associated files of various formats will be found in: http://www.gutenberg.org/2/9/0 /3/ 29 033 / Produced...
Ngày tải lên: 18/02/2014, 12:20
Tài liệu Báo cáo khoa học: Crystal structure of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase complexed with an analogue of 1,3-bisphospho-D-glyceric acid Selective inhibition by structure-based design docx
... methods Sources of substrates, cofactors and inhibitors The synthesis of 1 ,3- BPGA analogues used in this study has been described elsewhere [30 32 ]. NADH, NAD + , 3- phosphoglycerate (3- PGA), ATP, ... Biochemistry 34 , 14975–14986. 23. Due ´ e, E., Olivier-Deyris, L., Fanchon, E., Corbier, C., Branlant, G. & Dideberg, O. (1996) Comparison of the structures of wild- type and a N313T mutant of Escherichia ... endowment of unique kinetic and Correspondence to S. Ladame, University Chemical Laboratory, Cambridge University, Lensfield Road, Cambridge CB2 1EW, UK. Fax: + 44 12 23 336 9 13, Tel.: + 44 12 23 762 933 , E-mail:...
Ngày tải lên: 20/02/2014, 02:21
Tài liệu Báo cáo khoa học: Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid doc
... 20 03, revised 28 March 20 03, accepted 2 April 20 03) Eur. J. Biochem. 270, 231 2– 232 1 (20 03) Ó FEBS 20 03 doi:10.1046/j.1 432 -1 033 .20 03. 036 01.x This study reports the three-dimensional structure of IPDC ... (19 93) A thiamin diphosphate binding fold revealed by comparision of the crystal structures of transketolase, pyruvate oxidase and pyruvate decarboxylase. Structure 1, 95–1 03. Ó FEBS 20 03 3D structure ... consistent with a role of this helix in closure of the active site [36 ]. A model of the a-carbanion/enamine intermediate of the substrate indole -3- pyruvate with ThDP in the active site of IPDC was built...
Ngày tải lên: 20/02/2014, 11:20
Báo cáo khoa học: Crystal structure of salt-tolerant glutaminase from Micrococcus luteus K-3 in the presence and absence of its product L-glutamate and its activator Tris pdf
... determined part of the C-termi- nal domain in the T and TG structures suggests a revised F structure (PDB 3if5). There are disordered regions in the F (35 4-4 03 and 449- 456 aa), N (35 4 -37 6, 39 5-401 and ... residues Tyr27 c 1. 43 Tyr37 - d Tyr191 0.16 Tyr201 0.20 Tyr2 43 0 .33 Tyr2 53 1.16 Average ± SD 0.25 ± 0.12 0.68 ± 0.68 a Backbone atoms of the N-terminal domains (1 -30 5 aa) in the T and TG structures are ... (98.6) R merge (%) a,b Overall 11.1 12.4 11.9 13. 1 Highest-resolution shell 54.6 49.2 35 .6 41.2 Lowest-resolution shell 6.1 8.2 8.7 5.7 Multiplicity a 3. 6 (3. 6) 3. 7 (3. 7) 3. 5 (3. 5) 3. 1 (2.8) Unit-cell constants a(A ˚ )...
Ngày tải lên: 06/03/2014, 09:22
Báo cáo " Experiment for Bending Analysis of 3-phase Composite Plate in Ship Structure " doc
... 6,57 7,75 6, 73 5,56 - Experiment * 6,0 12 ,3 19,2 29,0 33 ,0 Analysis 6,5 13, 4 21,0 31 ,6 - 20%TiO 2 + 20%W800 + 60% AKAVINA polyester (sample type B) Error % 8 ,33 8,94 9 ,30 8,96 - Note: ... ) =+ ∂∂ ∂ + + ∂ ∂ + ∂ ∂ − ∂∂ ∂ ++ ∂ ∂ =+ ∂∂ ∂ + + ∂ ∂ + ∂ ∂ − ∂∂ ∂ ++ ∂ ∂ −= ∂ ∂ + ∂ ∂ 0 12 2 0 12 2 2 2 55 1 2 2 44 2 2 44 1 32 3 ,1 3 3 2 2 44 1 2 2 55 2 2 55 1 32 3 ,1 3 3 2 ψ ψψψ ϕ ϕϕϕ ψϕ I yxA DD xA D yA D I hyx w DD y w D I yxA DD yA D xA D I hyx w DD x w D hI z yx xyxyy yxy xyxyy yxx (3) ... bending deflection 3- phase composite Concentrate force Deflection (mm) 1kN 3kN 6kN 10kN Ultimate deflection Experiment * 7,6 14,2 20,8 32 ,4 34 ,3 Analysis 8,1 15 ,3 22,2 34 ,2 - 10%TiO 2 ...
Ngày tải lên: 14/03/2014, 13:20
Báo cáo khoa học: ˚ Crystal structure at 3 A of mistletoe lectin I, a dimeric type-II ribosome-inactivating protein, complexed with galactose pdf
Ngày tải lên: 31/03/2014, 01:20
Three essays on the credit growth and banking structure of Central and Eastern European countries
Ngày tải lên: 03/06/2014, 02:21
Báo cáo nghiên cứu khoa học: " Experiment for Bending Analysis of 3-phase Composite Plate in Ship Structure" potx
Ngày tải lên: 21/07/2014, 16:21
Báo cáo y học: " Crystal structure of an FIV/HIV chimeric protease complexed with the broad-based inhibitor, TL-3" docx
Ngày tải lên: 13/08/2014, 09:20
How to write a five paragraph essay
... effective five paragraph essay places the thesis, or argument, at the beginning of the essay so the writer can offer support for the argument in subsequent paragraphs. The essay also has ... five paragraph essay shows not only a writer’s ability to make an argument but organizational skills as well. A well-structured essay should draw the reader in, reveal a strong argument, offer ... serve as a map for the rest of the essay. It must be narrowly focused and able to be supported with evidence in subsequent paragraphs. A good thesis statement offers reasons , or “because...
Ngày tải lên: 19/08/2013, 14:15
Characterization of the Carbon Stable Isotope Ratio and Fatty Acid Structure of Zostera japonica in Coastal Areas
Ngày tải lên: 05/09/2013, 10:17
the meaning and structure of a narrative a systemic functional analysis
Ngày tải lên: 07/09/2013, 13:48
STRUCTURE OF POLYSACCHARIDES
... the extraction of cellulose. 2.1.2 β -(1 3) -Glucans There are a number of structural variations within the class of polysaccharides classified as β -(1 3) -glucans. The group of β -(1 3, 1→6) linked ... Chemical structure of alginate 2.1 Structural Features 9 Fig. 2.4. Structure of pullulan The polysaccharide possesses hydroxyl groups at position 2, 3 and 4 of different reactivity (Fig. 2.4). The structure ... solution of acetic acid. Chitin containing about 40% of GlcNAc moieties is insoluble while the soluble polysaccharide is named chitosan [38 ]. Fig. 2.10. Structure of chitin consisting of N-acetylglucosamin...
Ngày tải lên: 25/10/2013, 16:20
Structure of vibrated powders – numerical results
... Figs. 3. 13a 3. 13b, clusters of approximately 30 0 spheres which represent the corresponding structures are shown. It is evident that the two structures are fundamentally different, with the structure ... correctly, care must be 3. 2 The structure of shaken sand – some simulation results 39 0 0.05 0.1 0.15 0.2 0 0.1 0.2 0 .3 0.4 r P(r) Fig. 3. 9 Distribution functions F(r) for the radii r of the overlapping ... forma- tion of cooperative structures such as bridges [33 ], or indeed the very existence [21] of an angle of repose [ 23] ; neither would be possible in the presence of Brownian motion. In this...
Ngày tải lên: 01/11/2013, 08:20
A discourse analysis of college admissions essays in english
Ngày tải lên: 26/11/2013, 13:31