structure biology of disease and clinical electroretinography in human x linked retinoschisis xlrs
Báo cáo y học: " Changes in health-related quality of life and clinical implications in Chinese patients with chronic cough" pot
Ngày tải lên :
13/08/2014, 08:20
... analysis of data and took part in review of the manuscript, YW, XL and HL took part in the collection of cases and review of the manuscript, ZQ was in charge of design and coordination of the program, ... eligible for inclusion in case of the presence of an isolated persistent cough of > weeks, the absence of adventitious lung sounds on physical examination, normal findings on plain chest radiography, ... scales of SF-36, RE, GH and RP were affected in the most outstanding way (Table 2) whole, despite that the feelings of embarrassment, frustration and disturbance of sleep were more obvious in women...
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báo cáo khoa học: "Prognostic significance of STAT3 and phosphorylated STAT3 in human soft tissue tumors - a clinicopathological analysis" ppt
Ngày tải lên :
10/08/2014, 10:21
... Journal of Experimental & Clinical Cancer Research 2011, 30:56 http://www.jeccr.com/content/30/1/56 Page of Table Expression levels of STAT3 and pSTAT3 in benign, intermediate and malignant human soft ... AS and DD designed this study and carried out immnunohistochemistry staining, western blotting and RT-PCR and drafted the manuscript LM, and KB, provided the clinical samples and collected clinical ... paraffin sections stained with Hematoxylin and Eosin and the tumors were broadly classified into benign, intermediate and malignant Immunohistochemistry and evaluation Resected specimens were fixed...
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Báo cáo khoa học: " The role of NH4Cl and cysteine proteases in Human Papillomavirus type 16 infection" ppsx
Ngày tải lên :
12/08/2014, 04:21
... cathepsin B or cathepsin L protease, Figure Cathepsin B and L treatment of HPV16 increases binding Cathepsin B and L treatment of HPV16 increases binding Reporter virus binding was compared in 293 ... L enhanced infectivity by cleaving and removing a highly glycosylated mucin domain in the Ebolavirus glycoprotein and resulted in increased binding suggesting that cathepsins are indeed present ... protease treatment of HPV16 for hour can increase binding, that longer time incubation results in a loss of total binding, and that the increase in infection after protease treatment of reportervirions...
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Báo cáo khoa học: Intermodule cooperativity in the structure and dynamics of consecutive complement control modules in human C1r Structural biology docx
Ngày tải lên :
15/03/2014, 23:20
... proteases Intermodular and intramodular flexibilities are thought to be essential in these movements Expression of recombinant intact C1r [4] and its domain combinations in insect cells and bacteria, ... loop, and the presence of a tyrosine in strand C of CCP4 in place of an asparagine in C1r CCP2 (N379), and based on the results of the present perturbation study, we suggest that the inter-CCP flexibility ... buffer containing mm NaN3 in an H2O:D2O ratio of : 1, at pH values of 4.0, 4.5 and 7.0 Spectra typically contained 4K*64 data points in 2D experiments and 2K*256*64 data points in 3D experiments...
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Báo cáo khoa học: High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract Implications for Parkinson’s disease docx
Ngày tải lên :
16/03/2014, 11:20
... pathogenic agent, capable of passing the GI epithelial lining, might induce a-synuclein misfolding and aggregation in specific neurons of the intestinal neuronal plexuses and possibly also reach ... studies including investigations in human tissues, and that this has implications for how to interpret the role of the studied enzymes in health and disease Results The distribution and relative intensity ... corresponding rat tissues show expression only in duodenum, colon and rectum In both mouse and rat, Adh4 is found in the epithelial lining of upper GI tract including the tongue, esophagus and stomach,...
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Báo cáo hóa học: " Multiplexed methylation profiles of tumor suppressor genes and clinical outcome in lung cancer" potx
Ngày tải lên :
18/06/2014, 16:20
... participated in acquiring clinical samples and follow-up clinical information MSC participated in study design and coordination, data analysis and interpretation and final writing of the manuscript ... panel of candidate genes selected could be of clinical relevance for the clinicopathologic staging of human lung tumors MS-MLPA profiles for clinical outcome prognosis for lung cancer patients In ... analysis and interpretation, and drafted the manuscript PP and LG participated in acquiring clinical and laboratory data, data analysis and data interpretation and drafted the manuscript LG, JV, and...
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báo cáo hóa học: " Type D personality in the general population: a systematic review of health status, mechanisms of disease, and work-related problems" docx
Ngày tải lên :
18/06/2014, 19:20
... an independent predictor of negative health outcomes such as poor health status, (recurrent) myocardial infarction, and increased risk of mortality [4-7] Given the clinical relevance of findings ... and experimental evidence regarding the role of Type D personality in potential mechanisms of disease as well as work-related Type D personality and mechanisms of disease Type D personality and ... during experimental stress Type D was also associated with a decreased activity in the amygdala in response to fearful expressions [10], suggesting inadequate emotion-processing in the brain Finally,...
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Báo cáo y học: "Phenomenology and management of cognitive and behavioral disorders in Parkinson''''s disease. Rise and logic of dementia in Parkinson''''s disease" pptx
Ngày tải lên :
08/08/2014, 21:20
... elaboration of behavioral responses to challenging situations, including the processing of relevant information, problem solving, and planning ability Several tasks examining this require cognitive flexibility ... place of dementia in Parkinson's disease: A methodologic saga Advances in Neurology 1999, 80:403-408 Cummings JL: Intellectual impairment in Parkinson's disease: Clinical, pathologic, and biochemical ... Aarsland et al Reid et al 1988 1988 1988 1991 1992 1995 1996 1996 Retrospective, DSM-III Examination, Npsy Examination, DSM-III Examination, NPsy 2SD Examination, DSM-III Examination, DSM-IIIR Examination,...
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Báo cáo y học: "The Inventory of Personality Organisation: its psychometric properties among student and clinical populations in Japan" pptx
Ngày tải lên :
08/08/2014, 23:21
... for the primary and additional items using another randomly generated subset of students The fit of each model with the data was examined in terms of χ2 (CMIN), goodness -of- fit index (GFI), adjusted ... factor structure may emerge This issue should be studied in future works including clinical as well as non -clinical populations Our study does not prove a final model of the factor structure of the ... may be useful in both clinical and non -clinical settings as a measure of borderline personality pathology To assess predictive validity, we examined whether IPO scores at one point would predict...
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Báo cáo khoa học: "Real time PCR analyses of expression of E-cadherin, alpha-, beta- and gamma-catenin in human breast cancer for predicting clinical outcome" pps
Ngày tải lên :
09/08/2014, 07:21
... Journal of Surgical Oncology 2008, 6:56 The main structure of E-cadherin catenin complex consists of transmembrane E-cadherin, cytoplasmic proteins, called catenins (α-, β- and γ-catenin), and actin ... cut-offs for positivity and negativity We determined the expression of E-cadherin, α-, β- and γcatenin in human breast carcinomas using real time quantitative polymerase chain reaction and investigated ... counterstained in Mayer's haematoxylin and dehydrated in ascending grades of methanol before clearing in xylene and mounting under a coverslip Quantitative image analysis of immunohistochemical stains Image...
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Báo cáo y học: "Ultrasonography, magnetic resonance imaging, radiography, and clinical assessment of inflammatory and destructive changes in fingers and toes of patients with psoriatic arthritis" pot
Ngày tải lên :
09/08/2014, 10:21
... al Ratingen scoring system [11] by an experienced musculoskeletal radiologist (AV) blinded to clinical and other imaging findings Clinical examination All 25 persons underwent clinical examination ... US in 5% of the CTRL joints (6 in fingers and in MTP joints) in our study (Figure 3) Szkudlarek and colleagues found erosion-like changes in 1% of the MTP joints [14] and 0% of the finger joints ... ultrasonography, x- ray, and clinical examination, with MRI as standard reference method Sensitivities and specificities of US, x- ray, and clinical examination, with MRI as the standard reference...
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Ceftriaxone-induced up-regulation of cortical and striatal GLT1 in the R6/2 model of Huntington’s disease pps
Ngày tải lên :
10/08/2014, 05:21
... Effects of ceftriaxone on GLT1 expression in cerebral cortex and striatum at 13 weeks of age Immunoblots (A, C) and quantitative analysis (B, D) of the percentage ratio of GLT1/b-tubulin in cerebral ... dysregulation, including a possible decline in GLT1 activity, may play a role in several neurodegenerative diseases [5,24] In fact, a phase III clinical trial of ceftriaxone for treatment of amyotrophic ... blocking buffer Protein loading was normalized using b-tubulin immunoblotting as a loading control Chemiluminescent detection of HRP (SuperSignal West Pico; Pierce) was followed by exposure of...
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Báo cáo y học: "A knowledge synthesis of patient and public involvement in clinical practice guidelines: study protocol" doc
Ngày tải lên :
11/08/2014, 05:21
... and validating data extraction from publications Examples of questions in the interview guide include: descriptive information on existing PPIPs and their context of development, components of ... conceptualizing the development and effective implementation of CPGs International consensus on the importance of patient and public involvement in CPGs International experience of patient and public involvement ... in existing CPGs (e.g., prostate cancer screening) [42] In 2007, the Guideline International Network (GIN), an international network of 85 CPGs organizations, announced the creation of the GIN...
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Báo cáo khoa hoc:" Expression of estrogen and progesterone receptors in vestibular schwannomas and their clinical significance" docx
Ngày tải lên :
11/08/2014, 07:21
... immunofluorescence histochemical staining to detect estrogen-binding activity and found of tumors had estrogen-binding activity and the intensity of the staining was found to be much greater in the tumors from ... Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India The clinical parameters like age, sex, evidence of cutane- Figure Magnetic Resonance (MR) image of ... Sciences, Lucknow, India Five micron thick sections were obtained and the standard streptavidin biotin peroxidase immunohistochemical method was used for the expression of estrogen and progesterone...
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Báo cáo khoa hoc:" Histopathological grading of pediatric ependymoma: reproducibility and clinical relevance in European trial cohorts" pps
Ngày tải lên :
11/08/2014, 07:21
... resection; black line = CR-Gd II; red line = STR-Gd II; blue line = CR-Gd III; green line = STR-Gd III grade and outcome in an extensive study of children of all ages, including infants, that were ... (Figure 6) Following the joint review, discussion of (i) idiosyncratic cases encountered in clinical practice, and (ii) problems with evaluating types of necrosis in both grade II and grade III ... 8a-d) Association between outcome and clinical variables For each trial, outcome analyses were undertaken using clinical and pathological data The following clinical variables were considered:...
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báo cáo khoa học: " A knowledge synthesis of patient and public involvement in clinical practice guidelines: study protocol" ppsx
Ngày tải lên :
11/08/2014, 16:20
... and validating data extraction from publications Examples of questions in the interview guide include: descriptive information on existing PPIPs and their context of development, components of ... conceptualizing the development and effective implementation of CPGs International consensus on the importance of patient and public involvement in CPGs International experience of patient and public involvement ... in existing CPGs (e.g., prostate cancer screening) [42] In 2007, the Guideline International Network (GIN), an international network of 85 CPGs organizations, announced the creation of the GIN...
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Báo cáo y học: "Differential cytopathogenesis of respiratory syncytial virus prototypic and clinical isolates in primary pediatric bronchial epithelial cells" pdf
Ngày tải lên :
11/08/2014, 21:22
... passaging of RSV BT2a does not affect growth kinetics Differential chemokine/cytokine secretion following RSV A2 and clinical isolate infection Chemokines/cytokines are important mediators of innate ... adapted in limited passages on HEp-2 cells Indeed, a relatively low binding affinity to HS might explain the limited infectivity of the clinical isolates in our PBEC model Experiments are ongoing ... remain to be elucidated and are the subject of ongoing research As a prototypic strain, RSV A2 has been extensively passaged in vitro in continuous cell lines, such as HEp2 In contrast, the clinical...
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Báo cáo y học: "Molecular characterization of hepatitis A virus isolates from environmental and clinical samples in Greece" pptx
Ngày tải lên :
12/08/2014, 01:21
... (sewage sample from the Alexandroupolis treatment plant), KOM94-KOM89KOM64, XAN64-XAN65 and ALE05- ALE10 (clinical strains from the cities of Komotini, Xanthi and Alexandroupolis, respectively) ... (environmental and clinical) by employing previously validated primer sets [9] Sequencing and analysis of viral genomes All positive samples (environmental and clinical) were confirmed by sequencing of the ... population of about 250,000 inhabitants Sewage samples were also collected from both the entry and exit-points of the treatment plant of Alexandroupolis, a city of approximately 50,000 inhabitants...
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