structure activity relationships for predicting ecological effects of chemicals
Tài liệu Báo cáo khoa học: Structure-activity relationships of a-conotoxins targeting neuronal nicotinic acetylcholine receptors ppt
Ngày tải lên :
19/02/2014, 12:20
... recent discovery of GID has added to knowledge of the structure- activity relationships of a-conotoxins by revealing that the highly charged N-terminal tail contributes to a4b2 activity This was ... approach to developing structure- activity relationships of a-conotoxins has been to examine the effects of re-engineering the disulfide bonds A minimal scaffold has been found for ImI in which the ... that the diversity of conotoxin primary structures is likely to increase, and this will aid in the elucidation of structureactivity relationships and in the characterization of the nAChR subtypes...
- 7
- 492
- 0
Báo cáo khoa học: Structure–activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken docx
Ngày tải lên :
30/03/2014, 11:20
... (2001) Essential role of the conformational flexibility of Structure activity relationships of fowlicidin-1 42 43 44 45 46 47 48 helices and on the lipid binding activity of apolipophorin-III J ... Solution structure of fowlicidin-1 (A) Ribbon stereo-diagram of the restrained minimized average structure of fowlicidin-1 (B) Stereo-diagrams of the backbone trace of the 20 lowest energy structures ... Journal compilation ª 2006 FEBS Y Xiao et al Structure activity relationships of fowlicidin-1 Because of adoption of a well-defined structure in the presence of TFE or SDS, subsequent NMR experiments...
- 13
- 386
- 0
Ecological Effects of PrescribedFire Season A Literature Reviewand Synthesis for Managers
Ngày tải lên :
02/06/2014, 09:37
... The Forest Service of the U.S Department of Agriculture is dedicated to the principle of multiple use management of the Nation’s forest resources for sustained yields of wood, water, forage, ... Fuel Consumption and Fire Intensity Ecological Effects of Burning Season in Forested Ecosystems Trees Understory Vegetaton Soils Wildlife Ecological Effects of Burning Season in Chaparral and ... of burn season, we present associated data on fire severity, phenology of vegetation, and activity level/vulnerability of the fauna of interest at the time of the burns, whenever available Ecological...
- 85
- 287
- 0
Financial Frictions and Total Factor Productivity: Accounting for the Real Effects of Financial Crises pot
Ngày tải lên :
15/03/2014, 22:20
... because of the rate of growth of the price of tradable goods, which enters in the definition of the gross interest rate which governs the size of the wedge between the producer and user cost of intermediate ... data of (arguably large) Mexican firms listed on the stock market We calculate the cost of credit for the median firm as the ratio of the real value of interest payments to the real value of the ... ratio of 24 percent and can account for between 25 and 30 percent of the fall in aggregate output Higher values of κ imply a larger debt to GDP ratio, but also account for a larger fraction of the...
- 45
- 505
- 0
Báo cáo khoa học: Structure–activity relation for synthetic phenoxazone drugs Evidence for a direct correlation between DNA binding and pro-apoptotic activity pdf
Ngày tải lên :
31/03/2014, 07:20
... atmosphere of 5% CO2 in air [13] Cells were treated with drugs for 20 h Assessment of drug-induced apoptosis One of the early events of apoptosis is the loss of membrane asymmetry of phospholipids ... energy of binding of ActII–ActV to DNA per mol of ligand (Table 3) Discussion Examination of the cytotoxic effects in leukemic cells showed that cytotoxic activity (Figs and 3) was a function of ... value for DHbind for complex formation for ActIII–ActV with DNA Assuming that the nature of intercalation with DNA is similar for all the drugs investigated, then the additional enthalpy of complexation...
- 8
- 331
- 0
Báo cáo khoa học: " Dose-Incidence Relationships on the Prenatal Effects of Gamma-Radiation in Mice" pdf
Ngày tải lên :
07/08/2014, 15:20
... Fusion of thoracic vertebrae Absence of ribs Fusion of ribs Wavy ribs Hypoplasia of ribs Displasia of sternebrae Missing of sternebrae Hypoplasia of sternebrae Curvature of tibia Absence of metatarsal ... examined Fusion of cervical vertebrae Deformity of occipital bone Splitting of cervical vertebrae Separating of cervical vertebrae Abnormal ossification of coccygeal vertebrae Fusion of lumbar vertebrae ... after exposure to different doses of gamma-ray on 11.5 day of gestation Dose (Gy) Observations No of mother No of implants No of embryonic death No of fetal death No of resorption Prenatal mortality...
- 5
- 316
- 0
Báo cáo lâm nghiệp: "Use of stem diameter variations for detecting the effects of pathogens on plant water status" pptx
Ngày tải lên :
08/08/2014, 18:21
... depression of the stem, owing to the necrosis of the bark and vascular tissues They averaged 10 cm in length at the end of the experiment stem The stem diameter evolution of plants for the different ... growth was 1.57 mm for control plants, 1.44 mm for H mediterraneuminoculated plants and -0.32 mm for those inoculated with B stevensii The growth rate of the stem diameter of the non-inoculated ... sensitivity of LVDT sensors in detecting the real water status of the plant The micrometric measurement of shrinkage and swelling of stem diameter seems to be a sensitive indicator of plant response...
- 10
- 267
- 0
Báo cáo y học: "Acute phase reactants add little to composite disease activity indices for rheumatoid arthritis: validation of a clinical activity score" potx
Ngày tải lên :
09/08/2014, 06:22
... APRs provide little information on actual disease activity on top of that provided by the combination of several clinical components This was the case for all analyzed RA activity scores, despite ... disease activity A limitation of the CDAI is that many physicians not perform detailed joint counts in the assessment of RA disease activity [38] On the other hand, joint counts are also required for ... scores in this cohort would therefore be a surrogate of disease activity, rather than an independent measure of irreversible loss of function [30,31] Our introduction of the CDAI was not intended...
- 11
- 446
- 0
Báo cáo y học: " Psychiatric diagnoses and punishment for misconduct: the effects of PTSD in combatdeployed Marines" pot
Ngày tải lên :
11/08/2014, 16:22
... 992 (34.3)** AFQT, Armed Forces Qualification Test † Individuals who served
- 8
- 340
- 0
báo cáo khoa học: " Virtual harm reduction efforts for Internet gambling: effects of deposit limits on actual Internet sports gambling behavior" doc
Ngày tải lên :
11/08/2014, 18:20
... aggregates of betting activity (i.e., the aggregate number of bets, amount of money wagered, and amount of money won for fixed-odds and live-action sports betting per calendar day) for all participants ... total number of bets; (2) total amount of wagers; (3) net loss for fixedodds players (each of these groups n = 462); (4) total number of bets; (5) total amount of wagers; and (6) net loss for live-action ... message, each measure was computed for the period of time before as well as after the first receipt of a notification message (note that the day of receipt of the notification message was defined...
- 9
- 245
- 0
Báo cáo y học: "A new parameter using serum lactate dehydrogenase and alanine aminotransferase level is useful for predicting the prognosis of patients at an early stage of acute liver injury: A retrospective study" potx
Ngày tải lên :
13/08/2014, 13:20
... criteria Of course, a new strategy is required to prevent the progression of the disease The difficulty in predicting the prognosis of ALF is mainly attributable to incomplete elucidation of its ... recent reports of over-activation of macrophages in the liver, which is believed to cause hepatic hypoxia as a result of disturbance of the microcirculation [9-12] Although the importance of over-activation ... main process of ALF, at least for the nonacetaminophen type Meanwhile, LDH is an essential enzyme involved in anaerobic glycolysis and is responsible for the anaerobic transformation of pyruvate...
- 8
- 282
- 0
Báo cáo y học: "A general framework for quantifying the effects of DNA repair inhibitors on radiation sensitivity as a function of dose" pptx
Ngày tải lên :
13/08/2014, 16:21
... presence and absence of chemical inhibitors of PARP activity The variable nature and magnitude of the effects of PARP inhibition on clonogenic survival among these cell lines offered a useful setting ... radioprotective effect of the drug in this population Conventional analysis of the effects of DNA repair modifiers upon clonogenic survival is limited to quantifying the magnitude of change of a single ... untreated experiments, the merits of the approach were evaluated in terms of the capacity of the model to quantify and indicate the relative significance of the effects of PARP inhibition on the survival...
- 7
- 320
- 0
Báo cáo y học: "A proposed adaptation of the European Foundation for Quality Management Excellence Model to physical activity programmes for the elderly - development of a quality self-assessment tool using a modified Delphi process" ppt
Ngày tải lên :
14/08/2014, 08:20
... Physical Activity, Health and Leisure, Faculty of Sports, University of Porto, Porto, Portugal Department of Information Systems, University of Minho, Guimarães, Portugal Department of Physical ... contexts of PA programmes for the elderly in order to support its continuous improvement is, therefore, crucial Thus, the aim of this study was to develop a selfassessment tool for PA programmes for ... and Key performance results) 10 Discussion The main goal of this study was to describe the development of a quality selfassessment tool for PA programmes for the elderly To the best of our knowledge,...
- 30
- 369
- 0
A simplified method for conducting ecological studies of land snail communities in urban landscapes
Ngày tải lên :
14/09/2014, 20:14
... as the basis of our analysis: five units of 0.5 m2 each were searched for 15 We supplemented these data with a quadrat analysis: two quadrats of 0.0625 m2 each, with a depth of cm of soil removed ... Ecology of the city of Sofia: species and communities in an urban environment Pensoft, Sofia, pp 307–318 De Winter AJ, Gittenberger E (1998) The land-snail fauna of a square kilometre patch of rainforest ... the fauna of the sampled urban sites is representative of the common species found in semi-natural environments in this area and accounts for approximately one-third of the global fauna of the area...
- 7
- 262
- 0
Statistical learning approaches for predicting pharmacological properties of pharmaceutical agents
Ngày tải lên :
14/09/2015, 12:43
... 3.1.3.1Promiscuity nature of PXR activator structures and the selected molecular descriptors for classifying PXR activators 70 3.1.3.2 Performance of SLMs for predicting PXR activators ... profiles Historically, inappropriate pharmacological properties have been one of the primary reasons for the failure of drug candidates in the later stages of drug development Thus tools for predicting ... summarizes the performance of several regression-based SLMs for predicting pharmaceutical agents of specific pharmacokinetic, pharmacodynamic or toxicological property The performances of these studies...
- 234
- 358
- 0
(SPE 156394) A Numerical Model for Predicting the Rate of Sand Production in Injector Wells
Ngày tải lên :
26/09/2016, 11:03
... tension cut-off = initial yield tension cut-off = peak tension cut-off = residual tension cut-off = tension cut-off at HECS = tension cut-off at LECS T= square root of the second invariant of the ... Law of Conservation of Mass, the rate of the change of porosity is related to the rate of generated sand mass by the equation (Detournay et al., 2006): (6) where is the boundary surface area of ... below which the formation shouldn’t be perforated Water-weakening effect In water injectors, formation rock may lose some of its strength due to chemical and/or mechanical effects of water contact...
- 8
- 368
- 0
(SPE78168MS) New Model for Predicting the Rate of Sand Production
Ngày tải lên :
26/09/2016, 11:43
... approach between predicting the onset of sanding and its severity once it occurs The following formulation has been used for the onset of sanding calculations; i.e the calculation of the critical ... a formation element next to a circular hole The hole could be the wellbore (for open hole completion) or a perforation (for cased hole completion) The orientation of the wellbore or the perforation ... the maximum tangential total stress acting on the formation or perforation We note that for LF1 the formation is failed and sand is produced To be consistent...
- 9
- 583
- 1
ENCYCLOPEDIA OF ENVIRONMENTAL SCIENCE AND ENGINEERING - CHEMICAL EFFECTS: see EFFECTS OF CHEMICALS; AIR POLLUTANT EFFECTS; POLLUTION EFFECTS ON FISH CHEMICAL TREATMENT: see PHYSICAL AND CHEMICAL TREATMENT OF WASTEWATERS potx
Ngày tải lên :
10/08/2014, 20:20
... compares the performance of various systems Important emissions data for IGCC projects are presented at the end of the current review Additional information is presented below on the status of coal gasification ... gasification environmental effects A comparison of the impacts on water streams of various processes is given in Table Pruschek et al (1995) discusses the removal of pollutants from a coal gasification ... installation of simple cycle gas turbines for peaking power As of 1989 the maximum single gas turbine output is about 150 MW In the second phase a heat recovery boiler is used to generate steam for either...
- 5
- 439
- 0
ENCYCLOPEDIA OF ENVIRONMENTAL SCIENCE AND ENGINEERING - EFFECTS OF CHEMICALS docx
Ngày tải lên :
10/08/2014, 20:20
... There is need for more sensitive and reliable methods of testing effects of single chemicals, degradation products and mixtures External environmental effects must also be 280 EFFECTS OF CHEMICALS ... is a fungal carcinogen 278 EFFECTS OF CHEMICALS Ingestion of azoglucoside carcinogens with Cycad plants is probably the chief cause of liver cancer in Guam Cancer of the esophagus in Zambians ... determined by the food intake of that group Toxicity is the general term applied to adverse biological effects in man resulting from pollutants Effects may EFFECTS OF CHEMICALS range from lessened...
- 11
- 474
- 0
Báo cáo khoa học: MR solution structure of the precursor for carnobacteriocin B2, an antimicrobial peptide fromCarnobacterium piscicola Implications of the a-helical leader section for export and inhibition of type IIa bacteriocin activity pdf
Ngày tải lên :
07/03/2014, 15:20
... active peptide The goal of this study was determination of the 3D solution structure of preCbnB2 to assist in obtaining a molecular level understanding of the reduced activity of preCbnB2 (relative ... Fig Superimposition of preCbnB2 structures (A) Superimposition of the backbone of the leader peptide a-helix for 20 structures (B) Superimposition of the backbone of helix Both helix domains are ... importance of this helix for membrane-bound receptor recognition and consequent antimicrobial activity [2,10] For example, Fimland et al [42] have shown that interchange of large domains of different...
- 9
- 519
- 0