structural centralization extending the reach of the appeal courts and people apos s courts
STUDYING THE IMPACT OF HUMOR APPEAL IN TVC ON CONSUMER’S ATTITUDE TOWARDS BEER BRAND THE CASE OF HEINEKEN BEER
Ngày tải lên :
11/04/2016, 16:26
... advertisements is sometimes presented without any seriousness; (4) something ludicrous, which is just used for the purpose to laugh; (5) a satire, as sarcasm is used in some of the humorous advertisements ... Analysis By applying SPSS software to analyze: Descriptive Statistics: Descriptive statistics are used to describe the basic features of the data in a study They provide simple summaries about the ... about the sample and the measures Descriptive statistics provides frequencies, measures of central tendency and dispersion Together with simple graphics analysis, they form the basis of virtually...
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the politics of decentralization forests, power, and people
Ngày tải lên :
01/06/2014, 11:14
... At the same time, the state establishes all criteria and standards: classifying forests, and setting criteria and standards for all forest tariffs, forest products and forest areas (Resosudarmo, ... makes some suggestions for the future THE ISSUE OF DECENTRALIZATION Many of the studies discussed are based on the Center for International Forestry Research s (CIFOR s) study of the role of local ... ORGANIZATION OF THE BOOK The remainder of this book is organized into three main parts The first, focusing on thematic issues, raises important cross-cutting questions The second part offers case studies...
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báo cáo khoa học: " LgR5 expression and cancer stem cell hypothesis: clue to define the true origin of esophageal adenocarcinomas with and without Barrett’s Esophagus?" ppsx
Ngày tải lên :
10/08/2014, 10:21
... fluorescence of the reporter reaches a fixed threshold The difference (ΔCt) between the average Ct values of the samples in the target wells and those of the housekeeping gene (GAPDH) was assessed, ... 0.4643) Discussion Similar to other solid tumor entities [8], a stem cell hypothesis has been proposed for Barrett s esophagus (BE) and its association with EAC [13] However, this hypothesis has not ... to substantiate these findings Page 10 of 11 Acknowledgements The authors thank the assistance of Mrs Manuela Schneider and Mrs Sabine Gahn for their technical support This publication was funded...
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Regulation of DNA (cytosine 5) methyltransferase 1 in the cell cycle and its role(s) in doxorubicin mediated micronuclei formation
Ngày tải lên :
14/09/2015, 14:13
... correlates with their transcriptional silencing Transcriptionally active euchromatin regions such as CpG islands in the first exons and promoters of housekeeping and tissue-specific genes are usually ... protocols including cell synchronization studies, transient over-expression, siRNA-mediated depletion and luciferase reporter assays, the roles of the transcription factors E2F1 and Sp1, and the ... consensus sequence on the p21WAF1 promoter will not influence Sp1/Sp3 binding and transcription activity By contrast, methylation of CpG sites outside the consensus Sp1/Sp3 binding sites has been...
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Examination of Returns, Appeal Rights, and Claims for Refund pdf
Ngày tải lên :
06/03/2014, 19:20
... if the United States establishes that its position was substantially justified The position of the United States is presumed not to be substantially justified if the IRS: • Did not follow its ... another provision of the tax laws requires a specific burden of proof with respect to that issue Use of statistical information In the case of an individual, the IRS has the burden of proof in ... • All other cases, unless you qualify for the small case request procedure, or other special appeal procedures such as requesting Appeals consideration of liens, levies, seizures, or installment...
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Tài liệu Báo cáo khoa học: Structural insights into the substrate specificity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria ppt
Ngày tải lên :
18/02/2014, 16:20
... at the bottom of the subsite is conserved in ervatamins Compared to a Ser in the equivalent position of papain, the role of Leu here is to restrict the size and depth of the S2 subsite The S2 subsites ... us are used for investigation of the catalytic mechanism and substrate specificity and to understand the differences therein for this class of enzymes In order to identify the subsites of the ervatamins ... aromatic side chain at the P2 position of the substrate in the case of papain [26,41] Ervatamin-B shows Pro specificity at the P2 position of the substrate The S2 subsite of ervatamin-B is lined...
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Tài liệu Báo cáo khoa học: Influence of modulated structural dynamics on the kinetics of a-chymotrypsin catalysis Insights through chemical glycosylation, molecular dynamics and domain motion analysis pptx
Ngày tải lên :
19/02/2014, 05:20
... and protonation rates of Ser195 thus reducing the kinetics of catalysis The results also suggest that the dynamics of the calcium binding site in this structural class of proteins (chymotrypsin-fold ... molecular masses [36,37] These were employed in this work to address experimentally the questions of whether and how the enzymes structural dynamics inuence the kinetics of a-CT catalysis This was done ... between the proteins surface glycosylation, the resulting structural dynamic changes, and the inuence of these on the enzymes collective dynamics and catalytic residues Results and Discussion Chemical...
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Tài liệu Báo cáo khoa học: Mutational analysis of plasminogen activator inhibitor-1 Interactions of a-helix F and its neighbouring structural elements regulates the activity and the rate of latency transition pdf
Ngày tải lên :
20/02/2014, 11:20
... numbering is according to PAI-1 [29] The alignment is based on the three-dimensional structures of the relaxed conformations of the serpins (see text for details) Also shown is the serpin consensus sequence ... the serpin consensus and replaced them with the corresponding residues from the representative inhibitory serpins a1PI and ATIII As there are no discrepancies between the PAI-1 sequence and the ... insertion K325 is also conserved among serpins (K335 in a1PI) [2] and its substitution for A in a1PI, a1ACT and ATIII has been suggested to stabilize the stressed conformation of these serpins...
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Tài liệu Báo cáo Y học: Structural determinants of the half-life and cleavage site preference in the autolytic inactivation of chymotrypsin pdf
Ngày tải lên :
22/02/2014, 07:20
... FEBS 2001 cleavages of the sites were in the order: Tyr146/Asn147 ! Phe114 ! other sites The weakness of bands of fragments I and IV and the appearance of fragment II in the degradation of the ... amounts of trypsin (Table 2) The cleavage of the interdomain and autolysis loops To follow the autolysis of D-chymotrypsin and the mutants, the gel-electrophoretic patterns of their digests were ... !His/Asn147 !Ser D-chymotrypsin mutants displayed the same half-life and kinetics in both the presence and the absence of Ca21 ions, indicating that the Tyr146 !His and the Asn147 !Ser substitutions altered...
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The Power of “Independence”: Defending and Extending the Jurisdiction of Accounting in the UK pdf
Ngày tải lên :
06/03/2014, 15:21
... rehearsed within the sociology of the professions - such as the growth of corporate capitalism, the favourable terms of the Companies Acts, the closeness of accountants to their clients and the business ... executives- are themselves members of the same profession, and often the same association, as their major providers, such as their auditors Moreover, whilst the movement of accountants from industry ... regulators and clients In Abbott s model of ‘ the system of professions’, and in his three detailed case studies, there is scant consideration of the micropolitics of how professions actually organize...
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Báo cáo khoa học: NMR and molecular dynamics studies of an autoimmune myelin basic protein peptide and its antagonist Structural implications for the MHC II (I-Au)–peptide complex from docking calculations ppt
Ngày tải lên :
07/03/2014, 16:20
... distant from the side chain of Arg78 The side chain of Arg78 is less well defined, as in the case of aqueous solution, because of the absence of interactions with the side chains of Asp81 (in the ... defined by the backbone of the peptide The origin of this structural orientation in Me2SO is also the strong electrostatic interactions of the side chain of Arg78 with the side chains of Asp81 and Glu82 ... solute–box of 14 A The various systems comprised 3899 and 4516 SPC molecules for the agonist and the antagonist in water, respectively, and 817 and 927 Me2SO molecules for the agonist and the antagonist,...
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Báo cáo khoa học: Structural features in the C-terminal region of the Sinorhizobium meliloti RmInt1 group II intron-encoded protein contribute to its maturase and intron ppt
Ngày tải lên :
15/03/2014, 09:20
... transiently singlestranded DNA target sites, and that priming may include random nonspecific opposite-strand nicks, a nascent leading strand or de novo initiation of cDNA synthesis Because most of ... contains sequence motifs characteristic of the H-N-H family of endonucleases, interspersed with two pairs of cysteine residues [11,14,15] Deletion of the conserved En domain abolishes bottom-strand ... plasmid without the DNA target (pJBD129) was used as a negative control in the assays Schematic diagrams of the mobility assays are shown at the top (not drawn to scale) The SalI restriction sites...
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Báo cáo khoa học: The structural basis for catalytic function of GMD and RMD, two closely related enzymes from the GDP-D-rhamnose biosynthesis pathway pdf
Ngày tải lên :
16/03/2014, 01:20
... vectors encode N-terminal His6-tag fusions of their respective RMD proteins The enzymes used for in vitro assays were the N-terminal His6-tagged fusions of the P aeruginosa proteins Unless otherwise ... relative positions of the corresponding side chain, Arg220, the NADPH cofactor and the substrate analog hexose in the MUR1 structure (Fig 11) Some of the distances between these groups are rather long ... analysis indicates that the closest paralog of RMD is GMD The similarity of these proteins is also suggested by the fact that a number of GMDs are bifunctional, being able to catalyze the same stereospecific...
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Báo cáo khoa học: Structural basis for the erythro-stereospecificity of the L-arginine oxygenase VioC in viomycin biosynthesis docx
Ngày tải lên :
16/03/2014, 02:20
... describes the number of residues of the sequence used for the alignment The query and target structures are aligned in three dimensions on the basis of spatial closeness, minimizing rmsd, and ... previously for the substrate-binding residues in the active sites of CSL oxygenases [18], as they differ in regard to the sites of interaction with the substrate s side chain Most nonheme oxygenases ... acceptable substrates A challenging task for synthetic chemists is still the stereoselective synthesis of b-hydroxylated amino acids, given that these compounds are of significant interest, due to their...
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Báo cáo khoa học: Role of the structural domains in the functional properties of pancreatic lipase-related protein 2 pot
Ngày tải lên :
16/03/2014, 06:20
... uncovers the active site in the presence only of the bile compounds [32] The accessibility of E600 to the N2 active site is considerably increased in the presence of bile salts, which masks the slight ... concentrations only in the presence of colipase and bile salt, whereas the accessibility of the NcC2 active site depended only on the presence of bile salt The accessibility of the N2C2 and N2Cc active sites ... sensitivity of the Nc active site to E600 inhibition in the presence of bile salt Discussion Despite their structural similarities, the PLRP 2s form a subfamily that is clearly distinct from the...
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Báo cáo khóa học: Characterization of novel structural features in the lipopolysaccharide of nondisease associated nontypeable Haemophilus influenzae pptx
Ngày tải lên :
16/03/2014, 16:20
... b and d strains [7,8] Gene functions have been identified in those strains that are responsible for most of the steps in the biosynthesis of the oligosaccharide portions of the LPS molecules The ... (Micromass, Manchester, UK) in the negative ion Ó FEBS 2004 LPS glycoforms of nondisease associated NTHi strains (Eur J Biochem 271) 943 mode LPS-OH and OS samples were dissolved in a mixture of water/acetonitrile ... as in 11-OS-1 (data not shown) NMR spectroscopy on OS samples The 1H NMR resonances of OS material were assigned using chemical shift correlation techniques (DQF-COSY and TOCSY experiments) and...
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Báo cáo Y học: Monitoring the structural consequences of Phe12 fi D-Phe and Leu15 fi Aib substitution in human/rat corticotropin releasing hormone Implications for design of CRH antagonists pdf
Ngày tải lên :
17/03/2014, 10:20
... check the stereochemical quality of the peptide structure and provide the elements of the secondary structure, as well as other statistical parameters RESULTS NMR spectra–proton assignment The spin ... different resonances in the region 1.70–1.90 p.p.m Moreover, the stereospecific assignment of these methyl groups was achieved through analysis of the observed spin couplings and the intensities of dbN(i,i ... novel residues in the sequence of the molecule and the differences between the CRH analogue and the native structure [15] are also discussed The major goal of our study is the solution structure...
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Báo cáo Y học: Structural and serological relatedness of the O-antigens of Proteus penneri 1 and 4 from a novel Proteus serogroup O72 pptx
Ngày tải lên :
17/03/2014, 17:20
... 1H,13C HMQC spectrum The spin system of Glc was distinguished from those of Gal and GalNAc on the basis of the 3JH,H coupling constants values [18], and the spin systems of two GalNAc residues were ... highmolecular-mass LPS species of P penneri and but only weakly bound to low-molecular-mass LPS species These data ®tted well with a marked similarity of the structures and of the O-speci®c polysaccharides of ... O-antisera against these strains showed no signi®cant cross-reactivity with O-antigens of any strain from the other known Proteus serogroups Based on these data, we propose to classify P penneri and...
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Báo cáo Y học: Unique structural determinants in the signal peptides of ‘spontaneously’ inserting thylakoid membrane proteins pptx
Ngày tải lên :
18/03/2014, 01:20
... Primary sequences of signal peptides and translocated regions within spontaneously-inserting proteins, and structures of PsbX mutants (A) The figure shows the sequences of the signal peptides and ... regions of the mature proteins of Arabidopsis PsbX, Arabidopsis PsbW and spinach CFoII Also shown are the two signal peptides within the Arabidopsis PsbY polyprotein and the N-terminal regions of the ... The studies on the PsbW truncations focused on the role of basic residues in the N-domain, because previous work on M13 procoat and Sec-type signal peptides has shown that basic residues in the...
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