stress neuroendocrine hormones and wound healing human models

... Overview of Nutrition and Wound Healing Joseph A Molnar Chapter Carbohydrates and Wound Healing 15 Carol Ireton-Jones and George U Liepa Chapter Fat and Wound Healing .27 John ... Vitamin C and Wound Healing 121 Hideharu Tanaka and Joseph A Molnar Chapter Fat-Soluble Vitamins and Wound Healing 149 Michele M Gottschlich Chapter 10 Trace Elements and Wound Healing ... of wound healing, Ann Emerg Med., 17, 1265, 1988 36 Whitney, J.D and Heitkemper, M.M., Modifying perfusion, nutrition, and stress to promote wound healing in patients with acute wounds, Heart and...

Ngày tải lên: 22/03/2014, 19:20

... edge and the nucleus (*P < 0.01) (C) Three hours after wounding, the cells were fixed and immunostained with anti-a-tubulin serum and DAPI (scale bar = 20 lm) (D) CasWt and CasKo cells were wounded, ... wounded and, h later, cells were fixed and immunostained for Cas and Nck2 (scale bars = 20 lm) (B) CasWt and CasKo cells were wounded and, h later, cells were fixed and immunostained for Nck2 (C) CasWt ... between the nucleus and wound edge to levels seen in CasKo cells (Fig 5C) These data suggest that Src phosphorylates Cas to induce cell polarization and migration during wound healing Nck2 is crucial...

Ngày tải lên: 23/03/2014, 03:20

... molecules (A and B) in the unit cell; mouse Tyr303 (human Tyr307), Leu335 (human L339) and Ser725 (human Ala729) were also involved in the case of molecule A (Fig 4A), and Met68 (human Met69), ... , ligand exposure; , receptor exposure Phe71 (human Phe72) and Leu971 (human Leu975) in molecule B (Fig 4B) Arene–arene interactions were identified with Phe332 (human Phe336) and Phe974 (human ... molecules A and B, respectively Compared with the residues reported for QZ59-RRR in [20, fig 3], mouse Ser725 (human Ala729) and Ala981 (human Ala985) for the ligand in molecule A, and Phe71 (human...

Ngày tải lên: 29/03/2014, 22:21

... to healing wounds (1–5) As the molecular and cellular regulation of wound healing becomes better understood, new approaches to enhancing wound healing will become possible Animal models of wound ... 37 Incisional Wound Healing Model and Analysis of Wound Breaking Strength Richard L Gamelli and Li-Ke He Introduction The nature and mechanism of incisional wound healing has been and continues ... Excisional Wound Healing Excisional Wound Healing An Experimental Approach Stefan Frank and Heiko Kämpfer Introduction Wound healing disorders present a serious clinical problem and are likely...

Ngày tải lên: 11/04/2014, 10:39

... yllaudividni desuoh erew slamina ehT ]5[ noitarefilorp llec fo etar rehgih a dna ,tnetnoc nietorp dna AND retaerg a ,eussit noitalunarg dezinagro-retteb fo smret ni esnopser ralullec evitceffe na eveihca...

Ngày tải lên: 07/08/2014, 18:21

... centrifuged and the supernatants were collected and analyzed for IL6, PGE2, MMP1, and MMP13 with an ELISA kit (R&D Systems, Minneapolis, MN, USA) For mRNA analysis, the cells were lysed and total ... Italy) for the Randall-Selitto test paw A total of 10 rats were studied per group and the test was performed blind Rats were starved overnight and piperine was evaluated at doses of 20 and 100 mg/kg ... piperine on days and 9, despite the statistically insignificant analgesic effect of 20 mg/kg piperine Figure Analgesic and antiarthritic effects of piperine in rat models of paw edema and arthritic...

Ngày tải lên: 09/08/2014, 14:20

... other hand, being the medical science that specializes in skin and cutaneous physiology, deals with the essential and fundamental aspects of wound healing Due to its very nature, wound healing ... Cutaneous Wound Healing, edited by Vincent Falanga (Martin Dunitz); The Molecular and Cellular Biology of Wound Repair, edited by R.A.F Clark (Plenum Press); and The Epidermis in Wound Healing ... Ryan: Wound healing and current dermatologic dressings Clinics in Dermatology : 21–29, copyright 1990, with permission from Elsevier Science; Fig 2.5 is reprinted from Germain et al: Human wound healing...

Ngày tải lên: 10/08/2014, 18:20

... ulcer and to divert its course to a pathway of normal wound healing References Mehendale F, Martin P: The cellular and molecular events of wound healing In: Falanga V (ed) Cutaneous Wound Healing, ... G: The Healing Hand Man and Wound in the Ancient World, 2nd edn Cambridge, Massachusetts: Harvard University Press 1975; pp 29–67 The Swnw (Egypt) In: Majno G: The Healing Hand Man and Wound in ... area wound healing have been established, such as the Wound Healing Society and The European Tissue Repair Society Specialized journals are now published, such as Wounds, The Journal of Wound...

Ngày tải lên: 10/08/2014, 18:20

... DJ, et al: Common complications of wound healing: prevention and management Surg Clin North Am 1991; 71 : 1323–1351 124 Barbul A, Purtill W: Nutrition in wound healing Clin Dermatol 1994; 12 : ... Frostbite and pernio (chilblains) are associated with exposure to cold Frostbite usually affects fingers, toes, ears, cheeks, and nose In pernio, the proximal phalanges of the fingers and toes and ... bacterial infections such as syphilis and tuberculosis [87] and in three patients with multiple cholesterol emboli [88] Dermatitis and excoriations: Dermatitis and excoriations around an ulcer may...

Ngày tải lên: 10/08/2014, 18:20

... could impair the normal cutaneous ulcer healing process such as hypoxia in general and smoking in particular Ulcer Measurement and Patient Assessment wounds and ulcers However, there are various ... assessment of disease progression, and may The following basic data are needed at the initial examination and during the course of follow-up to quantify wound/ ulcer healing: Precise anatomical location ... normal healing process? In the event of lower limb edema that impairs ulcer healing, a specific workup should be conducted to determine the cause of the edema and appropriate treatment Evaluation and...

Ngày tải lên: 10/08/2014, 18:20

... to assess chronic wounds Wound Rep Reg 2000; : 264–269 10 Trengove NJ, Langton SR, Stacey MC: Biochemical analysis of wound fluid from nonhealing and healing chronic leg ulcers Wound Rep Reg 1996; ... NJ: Biochemical measurements of tissue and wound fluids In: Mani R, Falanga V, Shearman CP, Sandman D (eds): Chronic wound healing Clinical measurement and basic science, 1st edn London: WB Saunders ... Impediments to wound healing. Am J Surg 1998; 176 [Suppl] : 39S–47S 53 Niinikoski J: Effect of oxygen supply on wound healing and formation of experimental granulation tissue Acta Physiol Scand 1969;...

Ngày tải lên: 10/08/2014, 18:20

... H, et al: Infection and wound healing Wounds 2001; 13 : 127–131 100 Davis SC, Mertz PM, Eaglstein WH: The wound environment: implications from research studies for healing and infection In: Krasner ... Detrimental Effects of Bacteria on Wound Healing 136 10.2 Antibiotics and Antiseptics: Definitions and Properties 136 10.3 Infected Ulcers, Clean Ulcers, and Non -Healing ‘Unclean’ Ulcers 137 Infected ... Rodeheaver GT, Baharestani M, Brabec ME, et al: Wound healing and wound management: Focus on debridement Adv Wound Care 1994; : 22–36 40 Howes EL, Mandl I, Zaffuto S, et al: The use of Clostridium...

Ngày tải lên: 10/08/2014, 18:20

... E, et al: Influence of microcrystalline collagen on wound healing I Wound closure of normal excised and burn excised wounds of rats, rabbits and pigs Proc Soc Exp Biol Med 1972; 140 : 896–900 ... Drosou A: Wound microbiology and the use of antibacterial agents In: Rovee DT, Maibach HI (eds) The Epidermis in Wound Healing Boca Raton: CRC Press 2004; pp 155-182 32 Dychdala GR: Chlorine and chlorine ... healed at six weeks and 74% by 12 weeks, compared with ulcers treated by porcine dermis, where healing rates were 29% and 46%, respectively, after and 12 weeks While pinch grafting and punch grafting...

Ngày tải lên: 10/08/2014, 18:20

... Anstead GM: Steroids, retinoids, and wound healing Adv Wound Care 1998; 11 : 277–285 121 Pollack SV: Wound healing: A review Systemic medications affecting wound healing J Dermatol Surg Oncol 1982; ... JE: Wound healing Injury and abnormal repair N Engl J Med 1958; 259 : 275–285 130 Sandberg N: Time relationship between administration of cortisone and wound healing in rats Acta Chir Scand 1964; ... factors and angiogenesis in wound healing In: Ziegler TR, Pierce GF, 15_185_192 01.09.2004 14:05 Uhr Seite 191 191 References Herndon DN (eds) Growth Factors and Wound Healing: Basic Science and...

Ngày tải lên: 10/08/2014, 18:20

... enhances wound healing and lymphocyte immune responses in humans Surgery 1990; 108 : 331–337 36 Kirk SJ, Hurson M, Regan MC, et al: Arginine stimulates wound healing and immune function in elderly human ... pp 248–273 11 Albina JE: Nutrition and wound healing J Parenteral Ent Nutr 1994; 18 : 367–376 12 Kay SP, Moreland JR, Schmitter E: Nutritional status and wound healing in lower extremity amputations ... Ruberg RL: Role of nutrition in wound healing Surg Clin North Am 1984; 64 : 705–714 26 Lindstedt E, Sandblom P: Wound healing in man: tensile strength of healing wounds in some patient groups Ann...

Ngày tải lên: 10/08/2014, 18:20

... vacuum-assisted closure versus standard therapy of chronic non -healing wounds Wounds 2000; 12 : 60–67 31 Evans D, Land L: Topical negative pressure for treating chronic wounds (Cochrane Review) In: ... et al: Technological advances in wound bed measurements Wounds 2002; 14 : 58–66 Thomas S: Wound dressings In: Rovee DT, Maibach HI (eds) The Epidermis in Wound Healing Boca Raton: CRC Press 2004; ... of dressings and preparations for the treatment of wounds by second intention based on stages in the healing process Care Sci Pract 1986; : 13–17 Stotts NA: Seeing red and yellow and black The...

Ngày tải lên: 10/08/2014, 18:20

... 30 apneic rats and 30 control rats were randomly distributed for three different assays: migration, adhesion and wound 100 SaO2 (%) 95 90 85 Page of healing assays using rat MSC and primary rat ... basic mechanisms in the response to inflammation and endothelial damage: MSC migration and adhesion to endothelial cells and endothelial wound healing Methods Application of recurrent obstructive ... computed a wound closure index by comparing the initial and final (24 h) images of the endothelial wound MetaMorph software was used to identify the initial and final limits of the wound The closure...

Ngày tải lên: 12/08/2014, 11:22

... motility and wound healing We utilized an additional Transwell of differentiated NHBE cells and applied a scrape wound in the presence of 10 g/ml of cytochaliasin-D Not surprisingly, wound healing ... differentiation, cells were randomized into one of four groups (n = 6): 1) untreated control cells, 2) scrape wound only, 3) scrape and compression wounds, and 4) compression wound only Media was changed ... ET-1, EGF and PGE2 media content at 24 and 48 hours for the scrape only, compression only, and scrape and compression treated cells are shown in Fig Active TGF-2 and ET-1 (Fig 5A and 5B) demonstrated...

Ngày tải lên: 12/08/2014, 14:20

... studying the basic biology of epidermal wound healing and the healing of burn injuries as well as the effect of jaundice and diabetes on epidermal wound healing [8-11] In this model, a prolonged ... set of wounds: the first measurements following the induction of the wound and the second measurements on the fourth day of healing (Table 1) All blister wounds were covered with an air- and water ... manuscript, and helped perform the statistical analysis FG helped make the blister wounds and measurements and helped perform the statistical analysis VK and TIA-K helped draft the manuscript and helped...

Ngày tải lên: 13/08/2014, 16:21

... expressed genes during human and murine wound healing Immunohistochemical analysis of proteins encoded by array-identified dermally expressed genes during human and murine wound healing (a-d) In agreement ... of human wound RNA (five old and five young male subjects), from 0.5 μg of human normal skin RNA (three old and three young subjects), from μg of mouse wound RNA (six intact and six oxv mice) and ... (neutrophils and macrophages) and rate of re-epithelialization early in healing (three days postwounding; D3) and fibroblasts/blood vessels during the tissue remodeling phase (three months post-wounding;...

Ngày tải lên: 14/08/2014, 08:21