stem cell transplantation for spinal cord neurodegeneration

... without stem cell support Competing interests None declared References 10 11 12 13 14 Marmont AM, van Lint MT, Gualandi F, Bacigalupo A: Autologous marrow stem cell transplantation for severe systemic ... systemic lupus erythematosus with high-dose chemotherapy and haemopoietic stem- cell transplantation: a phase I study Lancet 2000, 356: 701-707 Traynor A, Burt RK: Haematopoietic stem cell transplantation ... hematopoietic stem cells are not necessary for re-engraftment While intensely immune suppressive, the regimen is not myeloablative and endogenous hematopoiesis would recover The hematopoietic stem cells...

Ngày tải lên: 09/08/2014, 01:23

... hematopoietic stem cell transplantation Hematopoietic stem cell transplantation (HSCT) is a complex multistep procedure involving mobilisation and harvesting of hematopoietic stem cells (HSCs) ... European Group for Blood and Marrow Transplantation, et al.: Autologous stem cell transplantation for systemic lupus erythematosus Lupus 2004, 13:168-176 Saccardi R, Kozak T, Bocelli-Tyndall C, ... Autologous stem cell transplantation in the treatment of systemic sclerosis: report from the EBMT/EULAR Registry Ann Rheum Dis 2004, 63:974-981 Tyndall A, Saccardi R: Haematopoietic stem cell transplantation...

Ngày tải lên: 09/08/2014, 10:23

... for conditioning; Phenytoin for prophylaxis of busulfan’s side affect Tacrolimus; methotrexate and mycophenolate mofetil (0.5 g twice a day on days to +28) for GVHD prophylaxis; Caspofungin for ... doi:10.1186/1756-8722-4-9 Cite this article as: Yu et al.: Allogeneic hematopoietic stem cell transplantation for acute leukemia with Gilbert’s syndrome Journal of Hematology & Oncology 2011 4:9 ... GS [8,9] List of abbreviations GS: Gilbert’s syndrome; allo-HSCT: Allogeneic hematopoietic stem cell transplantation; AML: acute myeloid leukemia; CR: complete remission; CT: Computed tomography;...

Ngày tải lên: 10/08/2014, 21:23

... data show that a cord blood with a sufficient cell number and more than out of of A, B and DRB1 loci is also a good alternative source for stem cells However, the low cell dose of cord blood results ... engraftment after haploidentical stem cell transplantation Leukemia 2004, 18:1835-1838 Passweg JR, Stern M, Koehl U, et al.: Use of natural killer cells in hematopoetic stem cell transplantation Bone Marrow ... techniques for positive selection of CD34 cells by using the CliniMACS system has provided enriched CD34+ stem cells with a powerful and reproducible TCD (median 4.5 logs) in grafts The median cell...

Ngày tải lên: 10/08/2014, 22:20

... allogeneic stem cell transplantation, severe disease is rare in patients after autologous stem cell transplantation Nevertheless, in patients with severe complications of infections after autologous stem ... relapsed and two cycles of DexaBEAM with stem cell harvest were applied We performed high-dose chemotherapy according to the BEAM protocol On day twelve after stem cell reinfusion he developed mental ... hematopoietic stem cell transplantation Leukemia 2002, 16:958-959 Vu T, Carrum G, Hutton G, Heslop HE, Brenner MK, Kamble R: Human herpesvirus-6 encephalitis following allogeneic hematopoietic stem cell transplantation...

Ngày tải lên: 12/08/2014, 04:21

... allogeneic stem cell transplantation, severe disease is rare in patients after autologous stem cell transplantation Nevertheless, in patients with severe complications of infections after autologous stem ... relapsed and two cycles of DexaBEAM with stem cell harvest were applied We performed high-dose chemotherapy according to the BEAM protocol On day twelve after stem cell reinfusion he developed mental ... hematopoietic stem cell transplantation Leukemia 2002, 16:958-959 Vu T, Carrum G, Hutton G, Heslop HE, Brenner MK, Kamble R: Human herpesvirus-6 encephalitis following allogeneic hematopoietic stem cell transplantation...

Ngày tải lên: 12/08/2014, 04:22

... blood stem cell transplantation; BMT, bone marrow transplantation; UBMT, unrelated bone marrow transplantation; T-UBMT, T -cell- depleted bone marrow transplantation; UCBT, umbilical cord blood transplantation; ... umbilical cord blood transplantation, unre­ lated BMT, and T -cell depleted unrelated BMT in chil­ dren Chronic GVHD was decreased after T -cell depleted unrelated BMT and umbilical cord blood transplantation ... odds for chronic GVHD Peripheral blood stem cell transplantation results in an increased risk for chronic GVHD compared with bone marrow transplantation Age at transplantation and a female donor...

Ngày tải lên: 12/02/2014, 19:20

... related to stem cells and Cell Transplantation, we felt it was important to take this opportunity to share these new develop‐ ments and innovations describing stem cell research in the cell transplantation ... investigating the role of stem cells in cell transplantation or regenerative medicine increased remarkably across all sections of the stem cell related journals The largest number of stem cell articles was ... interesting for our readers to follow the recent developments in the field of basic and clinical aspects of stem cells and cell transplantation Although we are close to finding pathways for stem cell...

Ngày tải lên: 18/02/2014, 04:20

... related to stem cells and Cell Transplantation, we feel it is important to take this opportunity to share these new developments and innovations describing stem cell research in the cell transplantation ... remain a stem cell, or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell Because of the unique abilities of stem cells, as ... investigating the role of stem cells in cell transplantation or regenerative medicine increased remarkably across all sections of the stem cell related journals The largest number of stem cell articles was...

Ngày tải lên: 20/02/2014, 08:20

... mis-positioning of motor neuron cell bodies outside the spinal cord By tracing the localization of BCCs with specific markers, Bron et al [8] found that these cells persist at the MEP in Npn-2 ... Boundary cap cell Axon Clustering of boundary cap cell at motor exit point (c) BCC Reverse signaling ? MIC Motor neuron ? Forward signaling Semaphorin 6A PlexinA Axon Inhibition of motor neuron cell ... wild-type mice, boundary cap cells (BCCs) express Semaphorin 6A (Sema6A) and motor neurons express members of the class A plexins Motor neuron cell bodies are caged in the spinal cord (b) Knock down of...

Ngày tải lên: 06/08/2014, 18:21

... repeats were performed for each biological replicate: this comprises gels for E6 and gels for E7 For each clone we ran three replicates for t0 (control) and three replicates for t48 hours Corresponding ... mES cells, this system allows the efficient and long-term overexpression of the transgene in a dose- and time-dependent manner It is therefore suitable for systematic expression of HSA21 cDNAs Cell ... state (that is, cells grown in the presence of Tc) with those derived from cells grown in a medium deprived of Tc for 48 hours (in other words, cells overexpressing the protein Runx1) For each of...

Ngày tải lên: 09/08/2014, 20:22

... of Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation in Experimental Lupus Nephritis Cell Transplant 2011, 20:245-257 32 Parekkadan B, Milwid JM: Mesenchymal stem cells as therapeutics ... mesenchymal stem cells generate osteosarcoma-like lesions in the lung Stem Cells 2007, 25:1586-1594 doi:10.1186/1423-0127-18-54 Cite this article as: Chang et al.: Mesenchymal stem cell transplantation ... intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke Stem Cells 2010, 28:1099-1106 Chou SH, Kuo TK, Liu M, Lee OK: In utero transplantation of human bone marrow-derived...

Ngày tải lên: 10/08/2014, 10:20

... hematopoietic stem cell transplantation (alloHSCT) provides a potentially curing treatment for refractory hematopoietic malignancies and is often the only available treatment for acute leukemia The transplantation ... Zhu P: Patterns of T -cell reconstitution by assessment of T -cell receptor excision circle and T -cell receptor clonal repertoire after allogeneic hematopoietic stem cell transplantation in leukemia ... mM MgCl2 After an initial denaturation at 95°C for min, 45 cycles consisting of 95°C for 30 s and 67°C for were performed The amplification was performed on MJ Research DNA Engine Opticon PCR cycler...

Ngày tải lên: 10/08/2014, 21:23

... post -transplantation (AML) cells and donor’s cells Polymorphism DNA repair mechanism Patient cells (pretransplantation) AML cells (posttransplantation) Donor cells XPA A23G NER Homozygous for ... informative and showed the coincidence of profile between AML blasts after transplantation and the donor’s cells, supporting full engraftment of the stem cell transplant as well as the donor cell- origin ... Homozygous for optimal DRC Homozygous for optimal DRC XRCC3 Thr243Met HRR Heterozygous for deficient DRC Homozygous for deficient DRC Homozygous for deficient DRC RAD51 G135C HRR Homozygous for optimal...

Ngày tải lên: 10/08/2014, 21:23

... disease after autologous stem cell transplantation The presence of circulating plasma cells and hyperammonemia are both known to be indicators of advanced disease Plasma cell neoplasm should be ... submission of this manuscript, which was considered by the editors to be a proxy for the patient's informed consent for the publication of the manuscript and accompanying images, in light of the ... data and the review of the manuscript RW performed immunohistochemical analysis YY drafted the manuscript and reviewed the literature, as did DA, who performed the final edits Consent The Institutional...

Ngày tải lên: 10/08/2014, 22:20

... hours for days (days -7 to -4) for a total of 16 doses, as well as cyclophosphamide 60 mg/kg IV × days (days -3 to -2) Pharmacokinetic measurements were not performed in this group Stem cell source ... disease after blood or marrow transplantation: a prospective cohort study of the European Group for Blood and Marrow Transplantation European Group for Blood and Marrow Transplantation Chronic Leukemia ... Ehninger G, Anasetti C: Conditioning with fludarabine and targeted busulfan for transplantation of allogeneic hematopoietic stem cells Blood 2003, 102:820-826 de Lima M, Couriel D, Thall PF, Wang X,...

Ngày tải lên: 10/08/2014, 22:21

... of beta cells for replacement therapy Successes and challenges for islet transplantation (a) Embryonic or induced pluripotent stem cells The first successful transplantation of islet cells into ... search for other stem/ progenitor cells in the pancreas While much attention has been paid to duct cells as the potential origin of new islets, there has also been a search for other stem cells ... rare multipotent stem cells that express insulin Cell Stem Cell 2011, 8:281-293 Ratajczak MZ, Liu R, Ratajczak J, Kucia M, Shin DM: The role of pluripotent embryonic-like stem cells residing in...

Ngày tải lên: 11/08/2014, 12:21

... Guinan EC: Multi-institutional use of defibrotide in 88 patients after stem cell transplantation Page of (page number not for citation purposes) Journal of Medical Case Reports 2009, 3:6164 http://jmedicalcasereports.com/jmedicalcasereports/article/view/6164 ... and the risk of hepatic venoocclusive disease in patients undergoing hematopoietic stem cell transplantation: a systematic review and meta-analysis Bone Marrow Transplant 2006, 37:677-686 Do you ... failure Consent Written informed consent was obtained from the patient for publication of this case report and accompanying images A copy of the written consent is available for review by the Editor-in-Chief...

Ngày tải lên: 11/08/2014, 17:21