staphylococcus aureus and nosocomial infection

... rate constants are similar between NP and MP and 2248 between HP and HPO in accordance with the similar shapes and sizes between NP and MP and between HP and HPO The different Kd values are proportional ... via the deprotonation and re-protonation of C2¢ and report a comprehensive equilibrium and kinetic study of SaDHNA and EcDHNA, which represent DHNAs from Gram-positive and Gram-negative bacteria, ... HP and 20 mM GA The reaction was initiated with 10 lM SaDHNA at 25 °C and quenched with M HCl The reverse reaction generated both DHNP and DHMP HP, DHNP, and DHMP were oxidized to HPO, NP, and...

Ngày tải lên: 19/02/2014, 00:20

... HR, Tice A, Cosgrove SE, S aureus Endocarditis and Bacteremia Study Group: Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus N Engl J Med 2006, ... more cases of MRSA strain infections have been shown in epidemiological studies [6,3] Sternal infection with S aureus is associated with high morbidity and mortality and carries a worse prognosis ... incidence of sternal wound infection after cardiac surgery is reported to be 0.4-5% [5] and Staphylococcus aureus is the most common pathogen isolated from sternal wound infections after cardiac...

Ngày tải lên: 10/08/2014, 09:22

... staphylococcal infections and biofilm of Staphylococcus aureus Figure 1.2 Conversed motifs of DEAD-box proteins Figure 1.3 The current model of Bacillus subtilis and Staphylococcus aureus ... complementary single-stranded DNA (ssDNA) and strand exchange on short double-stranded DNA (dsDNA) These DNA strand annealing and exchange activities are independent of Mg2+ or ATP binding and hydrolysis ... to severe life-threatening infections S aureus is a prominent infectious bacterium that causes nosocomial and post-surgical wound infections S aureus can cause minor infections as food poisoning...

Ngày tải lên: 20/05/2016, 15:28

... virulence factors during S aureus infections Calander and colleagues [29], using wild-type S aureus strain 8325-4 and its mutants lacking aureolysin, serine protease, and cysteine protease, demonstrated ... and 2000, and 52% had a different primary site of infection identified, 70% of which were S aureuspositive and 17% of which were methicillin-resistant In a retrospective analysis by Moumile and ... ofdifference ular-weight Staphylococcus aureus (MMP)-1 and MMP-3 mRNA in response to Staphylococcus aureus components separated by molecular-weight difference Fractionated S aureus culture supernatant...

Ngày tải lên: 09/08/2014, 08:23

... Meticillin-resistant Staphylococcus aureus (MRSA) is a prototypical nosocomial pathogen However, over the past few years, it is being increasingly reported as an important cause of serious skin and soft tissue infections ... skin and soft tissue infections have CA-MRSA infection [7] Reliable data on the prevalence of CA-MRSA infection in developing countries are lacking In two small studies from India, 1.4% and 11% ... haemoptysis and pulmonary aspiration She was intubated and mechanically ventilated By this time, the blood cultures drawn at admission were growing meticillin-resistant Staphylococcus aureus (MRSA)...

Ngày tải lên: 11/08/2014, 19:21

... methicillin-resistant Staphylococcus aureus J Hosp Infect 2000, 46:43-49 Lee SC, Chen KS, Tsai CJ, Lee CC, Chang HY, See LC, Kao YC, Chen SC, Wang CH: An outbreak of methicillin-resistant Staphylococcus aureus infections ... 25:678-684 Hospital Infection Society and British Society for Antimicrobial Chemotherapy: Revised guidelines for the control of methicillin-resistant Staphylococcus aureus infection in hospitals ... methicillin-resistant Staphylococcus aureus in ICU patients: morbidity, mortality and glycopeptide use Infect Control Hosp Epidemiol 2001, 22:687-692 Boyce JM: Methicillin-resistant Staphylococcus aureus: ...

Ngày tải lên: 12/08/2014, 20:21

... Gram-positive and Gram-negative bacteria and exerts bactericidal effects [68] Iclaprim is active against MSSA, community- and nosocomial- MRSA, VISA, VRSA, groups A and B streptococci, and pneumococci, and ... data for dalbavancin include phase II and III trials in both uncomplicated and complicated skin and skin structure infections, and catheter-related bloodstream infections Dalbavancin has been well-tolerated ... HR, Tice A, Cosgrove SE; S aureus Endocarditis and Bacteremia Study Group: Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus N Engl J Med 2006,...

Ngày tải lên: 13/08/2014, 18:22

... 1.4 Interaction of Staphylococcus aureus and macrophages Staphylococcus aureus (S aureus) is a Gram-positive pathogen and can be found as part of the resident flora of humans S aureus permanently ... Proteins influenced in abundance by infection with S aureus at h and/ or 24 h post infection 74 Table 18: Proteins influenced in abundance by infection with S aureus and IFN-γ stimulation 75 iv Summary ... were allowed to internalize Staphylococcus aureus and changes in the proteome were analyzed h and 24 h after exposure of BMMs to S aureus With an LC-MS/MS approach, 13 and 45 proteins of IFN-γ activated...

Ngày tải lên: 12/05/2016, 21:57

... E, Jarvinen A, Valtonen V, Ruutu P Trends and outcome of nosocomial and community-acquired bloodstream infections due to Staphylococcus aureus in Finland, 1995-2001 Eur J Clin Microbiol Infect ... superficial infections regarding anti PG and TA antibody levels (Fig 5) Discussion Staphylococcus aureus is a major human pathogen causing significant morbidity and mortality in both community and hospital ... Granstrom M, Julander I, Mollby R Serological diagnosis of deep Staphylococcus aureus infections by enzyme-linked immunosorbent assay (ELISA) for staphylococcal hemolysins and teichoic acid Scand J Infect...

Ngày tải lên: 02/11/2012, 11:08

... II and III, the only physical connection between domains G and II and domains III, IV and V In the S aureus EF-G structure, this loop has a bent conformation, and packs against domain III and ... structure of Staphylococcus aureus EF-G 3797 3798 S aureus [27,35] S aureus [27,35] S aureus [35] S aureus [27,35] S typhimurium [34] Leu456 His457 Leu461a Arg464 S aureus [27] S typhimurium [34] ... not conserved between S aureus and T thermophilus S typhimurium [34] Met670 a C S aureus [27] Gly666 Ile C S aureus [27] Gly664 Val B, C S aureus [27] Ser660 Ser Ala B S aureus [27] Arg659 Pro...

Ngày tải lên: 06/03/2014, 22:21

... 442–455 Lowy FD (1998) Staphylococcus aureus infections N Engl J Med 339, 520–532 Valdvogel FA (1995) Staphylococcus aureus (including toxic shock syndrome) In Principles and Practice of Infectious ... FnBPA and FnBPB from S aureus G Provenza et al B C D E F A490 nm A490 nm A Fig 15E11 epitopes are displayed on the surface of S aureus strains Attachment of S aureus to surface-coated elastin and ... compilation ª 2010 FEBS 4499 FnBPA and FnBPB from S aureus G Provenza et al Table S aureus and E coli strains used in this work Strain Relevant genotype Properties S aureus 8325-4 Wild type 8325-4...

Ngày tải lên: 06/03/2014, 22:21

... strand) and )33G, )35G, )46G, )56G and )68G (top strand) (Fig 3B) All the protected guanine bases except )56G are located in and around O1 and O2 Interestingly, )35G, )41G and )43G in O1 and ... to )48 and )52 to )87 regions of the top strand and )24 to )53 and )58 to )87 regions of the bottom strand were protected by CI (Fig 3B) The centers of these two sites harbor the 15 bp O1 and O2, ... 13 of Staphylococcus aureus 8325 Gene 289, 109–118 Das M, Ganguly T, Chattoraj P, Chanda PK, Bandhu A, Lee CY & Sau S (2007) Purification and characterization of repressor of temperate S aureus...

Ngày tải lên: 07/03/2014, 00:20

... stearothermophilus and 37 o C for Staphylococcus aureus Cells were harvested and resuspended in sterile water 100 µl suspension containing 10 cells of Bacillus stearothermophilus and Staphylococcus aureus ... stearothermophilus and (b) Staphylococcus aureus Figure SEM photographs of heat-treated bacteria at 140 °C for 20 seconds: (a) Bacillus stearothermophilus and (b) Staphylococcus aureus SEM images ... either 20 s (Figs 3a and 3b) or 10 (Figure 4a and b) show that Bacillus stearothermophilus still retained its typical rod shaped form (Figure 3a and 4a) and Staphylococcus aureus 62 Natura Montenegrina...

Ngày tải lên: 18/05/2014, 20:29

... of Methicillin-resistant Staphylococcus aureus in hospitals In J Hosp Infect Volume 39 British Society for antimicrobial Chemotherapy, hospital Infection society and the Infection Control Nurses ... impact of Methicillin Resistance in Staphylococcus aureus Bacteremia on Patient Outcomes: Mortality, Length of Stay, and Hospital Charges Infection Control and Hospital Epidemiology 26:166-174 ... RP, Perl TM: The significance of nasal carriage of Staphylococcus aureus and the incidence of postoperative wound infection Journal of Hospital Infection 1995, 31(1):13-24 12 Holden MTG, Feil EJ,...

Ngày tải lên: 20/06/2014, 04:20

... Hochkeppel, H and Doring, G Staphylococcus aureus capsular types and antibody response to lung infections in patients with cystic fibrosis J Clin Microbiol 1988, 26, 2205-2209 Anderson, J C Veterinary ... clinical isolates of Staphylococcus aureus Diagn Microbiol Infect Dis 1984, 2, 85-91 Baddour, L M., Lowrence, C., Albus, A., Lowrance, J H., Anderson, S K and Lee, J C Staphylococcus aureus microcapsule ... polysaccharides of Staphylococcus aureus Semin Infect Dis 1982, 4, 285-293 Keller, G M., Hanson, R S and Bergdoll, M S Molar growth yields and enterotoxin B production of Staphylococcus aureus S-6 with...

Ngày tải lên: 07/08/2014, 14:23

... 270 and 320 bp for and 10 isolates, respectively On the other hand, different sized amplicons of 100, 150, 200, 230, 240, 250, 270, 290 and 340 bp were observed for 8, 1, 1, 1, 2, 1, 1, and S aureus ... seg, sei and tst seemed to be the predominant toxin genes of S aureus isolated in Hesse, Germany The combined occurrence of the toxin genes seg and sei, sed and sej, sec and tst of S aureus, observed ... Table Pheno- and genotypic characteristics of S aureus isolates from Central Java, Indonesia and Hesse, Germany Comparative studies on pheno- and genotypic properties of Staphylococcus aureus isolated...

Ngày tải lên: 07/08/2014, 17:22

... studied (Table 1), 60.3% were Staphylococcus aureus and 39.7% coagulase-negative staphylococci Of these 35.1% were methicillin-resistant Staphylococcus aureus (MRSA) and 22.5% were methicillin-resistant ... methicillin-resistant and methicillin-sensitive S aureus clinical and carrier isolates Occurrence of multidrug resistance in methicillin-resistant and methicillin-sensitive S aureus clinical and carrier ... of S aureus isolates It has successfully been used to study the epidemiology of S aureus nosocomial infection and methicillin resistance [40,57-59] Nevertheless, PFGE is time-consuming and labor...

Ngày tải lên: 08/08/2014, 19:20

... prevalence and the severity of septic arthritis (a) The prevalence and (b) the severity of septic arthritis in NMRI mice (n = 19–30) on days and 10 following intravenous infection with S aureus strain ... scoring system Scand J Infect Dis 1994, 26:85-93 Kaandorp CJ, Dinant HJ, van de Laar MA, Moens HJ, Prins AP, Dijkmans BA: Incidence and sources of native and prosthetic joint infection: a community ... arthritis between days and 10 following S aureus infection in NMRI mice (n = 19–30) All treatments were initiated on day following intravenous inoculation of bacteria and continued until day...

Ngày tải lên: 09/08/2014, 03:24

... that SFK and Btk play differential roles in arachidonate release induced by Staphylococcus aureus (S aureus) and yeast-derived zymosan beads and that SFK act upstream of PI3K, PLCγ2 and MAP kinases, ... cellwall particles) and the Gram-positive bacterium S aureus, is differentially dependent on SFK and the Tec kinase Btk Src kinases act upstream of both Btk and the MAP kinases ERK and p38, thereby ... http://www.journal-inflammation.com/content/3/1/8 Figure Inhibition by PP2 or SKI-1 of zymosan- and S aureus- induced release of arachidonate Inhibition by PP2 or SKI-1 of zymosan- and S .aureus- induced release of arachidonate Macrophages...

Ngày tải lên: 11/08/2014, 08:21

... Gauduchon V, Vandenesch F, Etienne J: Involvement of Panton-Valentin leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia Clin Infect Dis 1999, 29:1128-1132 Labandeira-Rey ... interests Authors' contributions JCS, FE, and DH collected all data and drafted the manuscript DH and WW performed the PCR demonstration of the respective PVL-genes and subjected the respective isolates ... JC, Lina G, Bes M, Vandenesh F, Piemont Y, Brousse N, Floret D, Etienne J: Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotizing...

Ngày tải lên: 11/08/2014, 10:22