... SLC2A9 non-synonymous Arg265His variant and gout; evidence for a populationspecific effect on severity Jade E Hollis-Moffatt1, Peter J Gow2, Andrew A Harrison3, John Highton4, Peter BB Jones5, ... suggest that the effect of this variant is population specific, further confirming population heterogeneity in the association of SLC2A9 with gout Introduction Gout is a common inflammatory arthritis ... into non-Caucasian populations (parameters; number of populations assumed to be two, 30,000 burn-in period, 1,000,000 Markov chain Monte Carlo replications after burn-in) The 505 Caucasian control...
Ngày tải lên: 12/08/2014, 15:23
... reference population, were regressed on the conventional EBV of their 580 sires that were also included in the genomic reference population The corresponding R2 values indicate the fraction of the sons’ ... Correlations were greater than 0.9, Liu et al Genetics Selection Evolution 2011, 43:19 http://www.gsejournal.org/content/43/1/19 Page of Table Impact of reference population size on the SNP effect ... milk yield from conventional evaluations Nb of reference bulls Variance of SNP effect estimates§ Estimate of largest SNP effect$ Correlation of SNP effect estimates between evaluations B C D E F...
Ngày tải lên: 14/08/2014, 13:21
The effect of web search strategy on online purchase intention a web design element related cost benefit approach
... design on information search cost This section also discusses the cost/benefit of information search activity based on the interpersonal communication by Gatignon and Robertson (1986) Consumers’ ... expectation and determine the extent to which their expectation is confirmed Fourth, they form a satisfaction level based on their confirmation level and the expectation on which that confirmation ... …………………… …… 2.3.3 The Effect of Search Tasks on Search Strategies ………… 2.3.4 Cost and Benefit of Information Search ………………… 2.3.5 The Effects of Web Design on Information Search Cost … 2.4 Cost-Benefit...
Ngày tải lên: 15/09/2015, 17:11
Automated code generation by local search.pdf
... Population Size Generations Generational Model Generation Gap One Point Crossover Probability Point Mutation Probability Duplication Probability Pruning Probability Codons in Initial Population Maximum ... based on evolutionary computation The contribution of this paper is to describe an effective neighbourhood of a program, based on its integer string representation We also describe an effective local ... evolutionary computation By comparison, local search methodologies to automatically build systems have not yet received any significant research attention, and we see no reason why local search...
Ngày tải lên: 16/12/2012, 15:11
Investigation of thermal effect on exterior wall surface of building material at urban city area
... outdoor environment were analyzed This study can increase the awareness of urban planners, designers and decision makers on the importance of the construction material selection, which is not only for ... (Online) ©2012 International Energy & Environment Foundation All rights reserved 536 International Journal of Energy and Environment (IJEE), Volume 3, Issue 4, 2012, pp.531-540 Case 3-Foh Chong ... solar radiation (Sr) ISSN 2076-2895 (Print), ISSN 2076-2909 (Online) ©2012 International Energy & Environment Foundation All rights reserved International Journal of Energy and Environment (IJEE),...
Ngày tải lên: 05/09/2013, 15:28
Intake manifold design effect on air fuel mixing and flow for an LPG heavy duty engine
... simulation calculation ISSN 2076-2895 (Print), ISSN 2076-2909 (Online) ©2012 International Energy & Environment Foundation All rights reserved International Journal of Energy and Environment ... the combustion process As a conclusion, the distributions of the velocity fields and the air fuel friction are strongly depending on the intake manifold geometry Experimental validation To validate ... disposition on the engine test 1-Intake manifolds, 2-LPG vapo-regulator, 3-Fuel flow meter, 4-LPG pipes Figure Intake manifold effect on air-LPG ratio and SFC Conclusion The main conclusions we...
Ngày tải lên: 05/09/2013, 16:30
Báo cáo " Potential evapotranspiration estimation and its effect on hydrological model response at the Nong Son Basin" doc
... there are only four rain gauges, among those only one collects hourly data; one climatic station at Tra My; and one discharge gauge at Nong Son In general, the hydro-meteorological station network ... System) information AVHRR provides information on globe land classification at 30 s resolution [13] Fig 2.b shows the vegetation classification at 30 s resolution for the Nong Son catchment In ... hydrological response Potential description evapotranspiration model 2.1 Penman-Monteith equation Potential evapotranspiration can be calculated directly with the Penman-Monteith equation [3] as follows:...
Ngày tải lên: 05/03/2014, 16:20
Báo cáo khoa học: Deficiency in apolipoprotein E has a protective effect on diet-induced nonalcoholic fatty liver disease in mice pot
... perturbations [14,15] For this reason, it has been proposed that NAFLD should be included as a component of metabolic syndrome [16] Aging, hormonal imbalance and genetic predisposition may contribute ... separation of plasma lipoproteins by density gradient ultracentrifugation Fraction corresponds to the top fraction [containing chylomicrons (CHYL) and very low-density lipoprotein (VLDL)] HDL, high-density ... the circulation To determine the contribution of VLDL triglyceride secretion in apoE-mediated hepatic lipid accumulation, we compared the rate of hepatic VLDL triglyceride secretion between apoE)...
Ngày tải lên: 05/03/2014, 23:20
Accounting Standard (AS) 22: Accounting for Taxes on Income pdf
... Accounting Standard should be read in the context of its objective and the General Instructions contained in part A of the Annexure to the Notification.) Objective The objective of this Standard ... taxes that are payable on distribution of dividends and other distributions made by the enterprise Accounting for Taxes on Income 349 Definitions For the purpose of this Standard, the following ... to reverse first The application of the above explanation is illustrated in the Illustration attached to the Standard 352 AS 22 14 This Standard requires recognition of deferred tax for all the...
Ngày tải lên: 06/03/2014, 15:21
Working PaPer SerieS no 1150 / January 2010: Do bank loanS anD creDit StanDarDS have an effect on outPut? a Panel aPProach for the euro area doc
... securitisation, bank risk, capital and liquidity positions on monetary policy transmission See Bernanke et al (1999) for the seminal contribution on the balance sheet channel of monetary policy ... crisis have raised concerns about the e¤ectiveness with which monetary policy decisions are transmitted to the real side of the economy via its impact on banking sector conditions Monetary policy ... 1725-2806 (online) CONTENTS Abstract Non-technical summary Introduction A model on the banking lending channel 10 Data 14 Empirical methodology and results 15 Discussion 16 Conclusion 18 References...
Ngày tải lên: 15/03/2014, 10:20
Báo cáo khoa học: Betulinic acid-mediated inhibitory effect on hepatitis B virus by suppression of manganese superoxide dismutase expression pot
... expression with subsequent ROS generation in liver tissue Discussion This study demonstrates that BetA inhibits HBV replication by suppression of SOD2 expression with subsequent mitochondrial ... directly contribute to BetAinduced SOD2 suppression and HBV inhibition, whereas HBx translocation to mitochondria could be a consequence of BetA-induced SOD2 suppression and subsequent ROS generation ... BetA-mediated mitochondrial redox balance We found that BetA has a strong redox effect through suppression of SOD2 expression with subsequent mitochondrial ROS generation; even though ROS generation could...
Ngày tải lên: 16/03/2014, 01:20
Effect of Fund Size on the Performance of Mutual Funds Evidence from Iran pdf
... its effect on performance, and its relationship with the economic sphere and reducing transaction costs in a large volume Lindeen and Gros (2009) analyzed the effect of mutual fund size on performance ... fund size and performance Fund Size Fund Size Sharpe ratio Treynor Ratio Jensen differential measure Sortino Ratio Information Ratio Pearson Correlation Sig (2-tailed) Pearson Correlation Sig ... Pearson Correlation Sig (2-tailed) Pearson Correlation Sig (2-tailed) Pearson Correlation Sig (2-tailed) Pearson Correlation Sig (2-tailed) Pearson Correlation Sig (2-tailed) 0.421 (0.433) 0.227...
Ngày tải lên: 16/03/2014, 17:20
Which Aesthetic Has the Greatest Effect on Human Understanding? pdf
... three times, once for each question The order of presentation of the drawings and the questions was random, as was the orientation of the drawings The metric definitions give more detail on the extremes ... hypotheses, one for each aesthetic, first the significance of the effects of the level of diffÉculty (the q-/- dimension) needed to be confirmed After this confirmation that the q-/- dimension had ... relational reading of a graph drawing is considered, leaving the interpretive consideration of aesthetics for a later study The questions that are used in this experiment to measure relational...
Ngày tải lên: 16/03/2014, 18:20
great rock musicians their achievements and effect on music
... the attention of a record company by putting on an excellent show in a club However, unlike Dylan, the recognition they received wasn't direct They had played as the backup band on a Tony Sheridan ... Me Do" It sold like crazy locally, but only reached number 17 on the charts, still very good for a debut Their next single, "Please Please Me", made it to number one on the charts They had become ... Rock and roll has become one of America's greatest musical culture contributions Indeed, America would not be the same if it did not have rock and roll One of the reasons rock has become so great...
Ngày tải lên: 21/03/2014, 22:03
television violence and its effect on children essay
... is very impressionable Much of his personality is formed by the time he goes to his first day of kindergarten There is nothing wrong with him listening to music, watching television, or even playing ... about things Next time you wonder about how easily children can be convinced of something think of the myth of Santa Claus: One man bringing presents to the WHOLE world, in one sled, pulled by flying ... twelveth grade alone children listen to almost as many hours of rock music as they spend in school, for a full twelve years (Entertainment Monitor, 1995) As a teenager I can personally attest to...
Ngày tải lên: 21/03/2014, 22:52
television violence and its effect on children
... is very impressionable Much of his personality is formed by the time he goes to his first day of kindergarten There is nothing wrong with him listening to music, watching television, or even playing ... about things Next time you wonder about how easily children can be convinced of something think of the myth of Santa Claus: One man bringing presents to the WHOLE world, in one sled, pulled by flying ... desensitize children to violence and alter their perception of reality It can give them the idea that violence is the way to deal with problems and conflict Little is known of the actual numbers of how...
Ngày tải lên: 21/03/2014, 22:52
Báo cáo Y học: Extra terminal residues have a profound effect on the folding and solubility of a Plasmodium falciparum sexual stage-specific protein over-expressed in Escherichia coli pptx
... codon and the PCR product was cloned into the PvuII site of pRSET-C Subsequent sequence analysis as well as expression upon induction confirmed production of the fusion protein However, this construct ... a typically preferred construct This is a control construct designed to make wild-type Pfg27 without extensions or the D to N mutation Pfg27E: This construct has extensions at the N- and C-termini ... Pfg27A, we engineered two constructs Pfg27E and Pfg27F Once again, these constructs yielded only partially soluble fusion protein The postcleavage precipitation of Pfg27 from constructs Pfg27B–F indicated...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo đồ án trí tuệ nhân tạo: Mô tả không gian trạng thái bài toán người đưa thư (Travelling Saleman Problem – PST) và dùng giải thuật Local Search để giải quyết
... qua tổng độ dài đoạn đường For i = To MsgBox(duongdi(i)) g.DrawLine(pen2, point(duongdi(i)), point(duongdi(i + 1))) Next MsgBox("Tong dai doan duong la " & dodai) - Refresh lại combobox picturebox ... Dim font As New Font("arial", 16) For i = To point(i) = New Point(random(f), random(f + 1)) g.DrawEllipse(pen3, random(f) - 10, random(f + 1) - 10, 20, 20) g.DrawString(Convert.ToString(i), font, ... Continue For End If Else - Sau tìm đỉnh đến xóa hết thông tin đỉnh trước mảng a1(i,j) để đảm bảo không bị quay lại dem += duongdi(j + 2) = i For i = To a1(t2, i) = max a1(i, t2) = max Next Continue...
Ngày tải lên: 25/03/2014, 22:18
Always Leave Home Without It: A Further Investigation of the Credit-Card Effect on Willingness to Pay pptx
... than the values in the non-congruent conditions (diagonal cells versus non-diagonal cells; t 2.63, p ` 01; Wilcoxson Rank Sum: z 2.78, p ` 01) We conjecture that this effect might be due to ... card conditions For example, in the cash condition respondents may anchor their valuations using the amount of cash that they typically carry in their wallets In the credit card condition they ... study did increase donation size, the absolute amounts were small (average donations were 11¢ and 33¢ for the cash and credit card conditions) Second, Feinberg's studies only manipulated exposure...
Ngày tải lên: 29/03/2014, 03:21