stage 4 small cell lung cancer clinical trials

Báo cáo khoa học: "Clinical outcomes of stereotactic body radiotherapy for stage I non-small cell lung cancer using different doses depending on tumor size" ppsx

Báo cáo khoa học: "Clinical outcomes of stereotactic body radiotherapy for stage I non-small cell lung cancer using different doses depending on tumor size" ppsx

... 70 all patients stage IA patients treated with 48 Gy in 4 fractions stage IB patients treated with 52 Gy in 4 fractions all patients stage IA patients treated with 48 Gy in 4 fractions stage IB patients ... IA Stage IB Prescribed dose (in 4 fractions) All 44 Gy 48 Gy 52 Gy Patient number 1 24 2 85 37 Age (years) Range (median) 29-89 (77) 67, 70 58-87 (77) 29-89 (78) Gender Male 84 1 54 29 Female 40 ... 65 2 47 16 1 48 0 31 17 2110 74 Tumor size (mm) Range (median) 12-55 (27) 12, 14 15- 34 ( 24) 31-55 (35) Operability Operable 40 2 27 11 Non-operable 84 0 58 26 Histology Adenocarcinoma 66 2 46 18 Squamous...

Ngày tải lên: 09/08/2014, 09:20

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Báo cáo hóa học: " Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer" pdf

Báo cáo hóa học: " Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer" pdf

... lung cancer patients. Methods: EGFR mutation status was analyzed by DNA assays, and compared with IHC results in five non -small- cell lung cancer (NSCLC) cell lines and tumor samples from 78 stage ... 70 343 1 94 340 60 Age, years range 36-85 42 -83 27-88 median 64 67 59.9 Sex male 28 31 36 female 50 30 34 Ethnicity Caucasian 78 61 0 0 0 Asian 0 0 70 343 60 Smoking history smokers 33 37 41 non-smokers ... Non -small- cell lung cancer harbouring mutations in the EGFR kinase domain. Clin Transl Oncol 2010, 12:75-80. 9. Gazdar AF: Activating and resistance mutations of EGFR in non -small- cell lung cancer: ...

Ngày tải lên: 18/06/2014, 16:20

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Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot

Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot

... = 4. 64 0.011 V40 8.20% (3.29-13.61%) = 5.91, SD = 2 .48 = 9.26, SD = 3.75 0.015 V45 7 .42 % (2.73-10.99%) = 4. 41, SD = 2.25 = 6. 54, SD = 3 .47 0.007 V50 7.07%(1. 94- 8.82%) = 3.15, SD = 1. 94 = 4. 89, ... = 2 .40 0.001 V5 58.73% (32.89-97.65%) = 58 .43 , SD = 16.57 = 69.23, SD = 12 .47 0.006 V10 42 .16%(25.28-83. 34% ) = 41 .13, SD = 12.69 = 52 .42 , SD = 11.05 0.001 V15 29.53%(16 .46 -58.51%) = 28. 94, ... limited stage small cell lung cancer. Int J Radiat Oncol Biol Phys 1999, 43 :39 -45 . 31. Rancati T, Ceresoli GL, Gagliardi G, Schipani S, Cattaneo GM: Factors predicting radiation pneumonitis in lung...

Ngày tải lên: 09/08/2014, 08:23

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Báo cáo khoa học: "The effect of bioequivalent radiation dose on survival of patients with limited-stage small-cell lung cancer" pdf

Báo cáo khoa học: "The effect of bioequivalent radiation dose on survival of patients with limited-stage small-cell lung cancer" pdf

... limited -stage small cell lung cancer. [http:// clinicaltrials.gov/ct2/show/NCT0 043 3563]. 27. Three different radiation therapy regimens in treating patients with limited -stage small cell lung cancer ... limited -stage small- cell lung cancer. Int J Radiat Oncol Biol Phys 2003, 56:355-359. 5. Roof KS, Fidias P, Lynch TJ, Choi NC: Radiation dose escalation in limited- stage small- cell lung cancer. ... in lung cancer: small- cell lung cancer (SCLC). Int J Radiat Oncol Biol Phys 2008, 72:327-3 34. 33. Roof KS, Fidias P, Lynch TJ, Choi NC: Radiation dose intensification in limited -stage small- cell...

Ngày tải lên: 09/08/2014, 09:20

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Báo cáo khoa học: " Comparison of outcomes in patients with stage III versus limited stage IV non-small cell lung cancer" docx

Báo cáo khoa học: " Comparison of outcomes in patients with stage III versus limited stage IV non-small cell lung cancer" docx

... prospective clinical studies are needed. Keywords: Stereotactic Body Rad iotherapy, Oligometastases, Non -Small Cell Lung Cancer Background Non -small cell lung cancer (NSCLC) is the leading cause of cancer ... limited metastatic stage IV. Fifty-five of the 94 patients with initial stage III NSCLC ( 74% ) developed radiographically apparent metastases, of whom 44 developed limited metastatic stage IV disease ... of 7 RESEARC H Open Access Comparison of outcomes in patients with stage III versus limited stage IV non -small cell lung cancer Praveena Cheruvu 1 , Su K Metcalfe 1 , Justin Metcalfe 1 , Yuhchyau...

Ngày tải lên: 09/08/2014, 09:20

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Báo cáo khoa học: "Clinical Analysis of stereotactic body radiation therapy using extracranial gamma knife for patients with mainly bulky inoperable early stage non-small cell lung carcinoma" pot

Báo cáo khoa học: "Clinical Analysis of stereotactic body radiation therapy using extracranial gamma knife for patients with mainly bulky inoperable early stage non-small cell lung carcinoma" pot

... .002 .961 4. 638 .031 .895 . 344 3~5 cm .002 .961 10.977 .001 4. 541 .033 5~7 cm 4. 638 .031 10.977 .001 .108 . 742 >7 cm .895 . 344 4. 541 .033 .108 . 742 Wu et al. Radiation Oncology 2011, 6: 84 http://www.ro-journal.com/content/6/1/ 84 Page ... limited stage small cell lung cancer: analysis of CALGB phase III trial 9235. Lung Cancer 2008, 62:92-98. 9. Paumier A, Le Pechoux C: Radiotherapy in small- cell lung cancer: where should it go? Lung ... limited-disease small cell lung cancer: the Japan Clinical Oncology Group (JCOG) trial 0202. Radiation Oncology 2009, 4. 11. Ball D: Stereotactic radiotherapy for nonsmall cell lung cancer. Current Opinion...

Ngày tải lên: 09/08/2014, 09:20

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Báo cáo khoa học: "Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study" pps

Báo cáo khoa học: "Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study" pps

... patients with operable lung cancer. A randomized phase III trial of Radiosurgery Or Surgery for operable Early stage (stage 1A) non -small cell Lung cancer (ROSEL, ClinicalTrials.gov ID = NCT00687986) has ... body radiotherapy for stage I non -small cell lung cancer. Radiother Oncol 2007, 85 :42 9 -43 4. 39. Sinha B, McGarry RC: Stereotactic body radiotherapy for bilat- eral primary lung cancers: the Indiana ... inoperable early -stage lung cancer. J Clin Oncol 2006, 24: 4833 -48 39. 43 . Senan S, Haasbeek NJ, Smit EF, Lagerwaard FJ: Stereotactic radio- therapy for centrally located early -stage lung tumors. J...

Ngày tải lên: 09/08/2014, 09:22

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Báo cáo khoa học: "Radiotherapy quality assurance review in a multi-center randomized trial of limited-disease small cell lung cancer: the Japan Clinical Oncology Group (JCOG) trial 0202" pptx

Báo cáo khoa học: "Radiotherapy quality assurance review in a multi-center randomized trial of limited-disease small cell lung cancer: the Japan Clinical Oncology Group (JCOG) trial 0202" pptx

... committee, Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center 5-1-1 Tsukiji, Chuo-ku, Tokyo 1 04- 0 045 , Japan and 3 JCOG lung cancer ... Tamura 3 Address: 1 Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center, 5-1-1 Tsukiji, Chuo-ku, Tokyo 1 04- 0 045 , Japan, 2 JCOG ... time 21 – 42 days NA > 42 days Interfraction interval ≥ 5.5 hrs 4 – 5.5 hrs or < ;4 hrs (once) < 4 hrs more than once Organs at risk Spinal cord ≤ 36 Gy Neither PP nor VU > 39 Gy Lung ≤...

Ngày tải lên: 09/08/2014, 09:22

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báo cáo hóa học:" Randomized phase II study with two gemcitabine- and docetaxel-based combinations as first-line chemotherapy for metastatic non-small cell lung cancer" docx

báo cáo hóa học:" Randomized phase II study with two gemcitabine- and docetaxel-based combinations as first-line chemotherapy for metastatic non-small cell lung cancer" docx

... (B). 0 4 8 121620 242 8323 640 444 852 Weeks 0 0.2 0 .4 0.6 0.8 1 TTP Patients Events (%) Arm A 35 33 ( 94. 3) Arm B 34 32 ( 94. 1) A 0 4 8 12 16 20 24 28 32 36 40 44 48 52 Weeks 0 0.2 0 .4 0.6 0.8 1 Survival Patients ... 14 (35) 12 (29.3) Other NSCLC 4 (10) 6 ( 14. 6) Site of disease Lung ± lymph nodes 14 (35) 14 ( 34. 1) Lung and 1 metastatic site 12 (30) 15 (36.6) Lung and ≥ 2 metastatic sites 9 (22.5) 10 ( 24. 4) Extra-pulmonary ... Estimating the world cancer burden: Globocan 2000. Int J Cancer 2001, 94: 153-156. 2. Non -small Cell Lung Cancer Collaborative Group: Chemotherapy in non small cell lung cancer: a meta-analysis...

Ngày tải lên: 18/06/2014, 15:20

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Báo cáo hóa học: "Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins" ppt

Báo cáo hóa học: "Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins" ppt

... for clinical- pathological reasons are often divided into two broad categories: small cell lung cancer (SCLC) and non -small cell lung cancer (NSCLC). All major histological types of lung cancer ... pathogenesis of lung cancer. Annu Rev Physiol 2002, 64: 681-708. 13. Syrianen KJ: HPV infections and lung cancer. J Clin Pathol 2002, 55:885-891. 14. zur Hausen H: Papillomaviruses and cancer: from ... development of small cell lung cancer induced by HPV E6/E7 oncoproteins Tonia Buonomo 1 , Laura Carraresi 2 , Mara Rossini 3 , Rosanna Martinelli 1 ,4* Abstract Background: Lung cancers consist...

Ngày tải lên: 18/06/2014, 16:20

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