stability of the steady state solutions

... value of ~ can be used as a cut-off to demarcate the plastic zone from the rest of the domain, the cut-off used here being 3% of the maximum value of ~, over the domain Results and discussion The ... is the unit outward normal to the interface (iii) Separation force (S) The separation force is the resultant of the vertical component of the stress vector on the upper half of the die Since the ... for four sets of process variables, these four sets being so chosen that comparison of the contours of the first set with any of the successive sets illustrates the effect of one of the three process...

Ngày tải lên: 24/11/2016, 18:09

... step in the events that lead to aggregation and amyloid fibril formation [12,13,23] In the case of T70N, although the stability of the native state is lower than that of the WT protein, the transient ... between the levels of expression in the different experiments (Table 2) The results show a clear relationship between the thermal stability of each variant and the level of protein secreted to the ... investigating the secreted levels of a larger number of lysozyme variants, a highly significant correlation has been identified between the level of secreted protein and the thermostability of the native state...

Ngày tải lên: 19/02/2014, 08:20

... enables the assessment of test coverage and the further elaboration on the test, i.e., the verification of the test design and the synthesis of concrete stimuli that comply to it by covering the ... of the subsystems that contribute to the processing of the test signals in the system under test 5.1.2 Limitations of the concept The procedure is based on the uniformity hypothesis and can therefore ... let the frequency bin number k of the DFT of one frame of signal x at discrete time n be Xn (k) Let Yn(k) be the according value of signal y Then, the corresponding frequency bin Hn(k) of the...

Ngày tải lên: 20/06/2014, 22:20

... carried out the mathematical calculations, participated in the interpretations of the results and drafted the manuscript JJAG conceived of the study, participated in the analysis of the results ... precedence of the heat flux vector to the temperature gradient at all In fact, whether the heat flux vector precedes the temperature gradient or not depends on the combined effects of the thermal ... the difference of the time delays t = tq-tT These studies have pointed out that the usefulness of the Cattaneo-Vernotte and DPL exact models is limited In this study, by means of the method of...

Ngày tải lên: 21/06/2014, 04:20

... noise Therefore, if the frequency range of interest is from f1 to f2 (where f1 > and f2 ≥ f1 + T −1 ) and the desired RMS of the synthesized signal is r, then the target values for the synthesis ... section describes the synthesis of a signal that allows measuring the frequency response over the whole bandwidth of the hearing instrument under test The idea is to measure the effect of the noise reduction ... smoothing [21] These windows were taken from the last five seconds of the test run in order to observe the steadystate condition The result of this measurement is shown in Figure 3: the shown frequency...

Ngày tải lên: 21/06/2014, 22:20

... level of steady state reduction of 8thioacetamido-FAD However, the truncation of the activation domain resulted in much lower rate of superoxide generation (Fig 2) and a very low steady state ... domain in p67phox regulates the steady state reduction of FAD in gp91phox 29 Table Effects of cytosolic factors on NADPH oxidase activity and on the steady state reduction of FAD and heme 8Thioacetamido-FAD ... of 8-thioacetamido-FAD (Fig 3) The activation domain is not involved in the interaction with Rac1 or p47phox [10] Therefore, the truncation of the activation domain suppresses the reduction of...

Ngày tải lên: 07/08/2014, 14:22

... meaning This is the antithesis of the universe of meaning in which existed the medieval society following the Papal Revolution.37 The ‘General Will’ as the source of the sovereignty of the nation ... market The laws of commerce were the laws of nature which were the laws of God The consequent de-moralisation of the economy represented the institutional separation of politics from the economy, ... by the bonds of sociality’ Independent states were to obey the laws of nature which were akin to the natural laws of the Hobbesian presocial man in the war of all against all.9 This idea of nature...

Ngày tải lên: 01/11/2013, 08:20

... of history upon an attempted synchronisation of the nation and the state The nation is the biological, organic cement of the state Hegel’s writing on the topic embodied the nationalist view of ... was sought through the vehicle of the state 9.2 Logical aspects of the modern state In sharp contrast to the shared myths, language and genealogy of the nation or tribe, the state can be something ... constitutes the concept of the power of the crown and which, as the ideality of the whole state, has not up to this point attained its right or its existence’.52 For Hegel, the subjectivity of the nation...

Ngày tải lên: 01/11/2013, 08:20

... table The calculating results based on the elastic theory are presented in table Figure is graph of the elasto-plastic instability case The comparison between the elasto-plastic instability and the ... remarks as follows a) The critical loads determined according to the elastic theory are much greater than those according to the theory of elasto-plastic processes when the thickness of cylindrical ... value, the difference between the critical loads found by basing on two theories is very little Therefore for the slender cylindrical shells, calculating based on the elastic theory is reliable c) The...

Ngày tải lên: 13/02/2014, 04:20

... and provide independent evidence for heterogeneity of the A -state A -state stability Figure shows the thermal denaturation profiles of the A -state of cytochrome c, as obtained from ellipticity values ... in favor of the LS (IHM) A -state (that characterized by the native Met80–heme bonding) In the case of the K88E ⁄ T89K mutant, the presence of a relevant amount of LS species already in the aciddenatured ... destabilization of the HS acid-denatured form, with further formation of the LS (IHH) A -state; (b) for the slow phase, to formation of the LS native-like (IHM) A -state Unlike wild-type cytochrome c, once the...

Ngày tải lên: 19/02/2014, 05:20

... binding of the polyadenylated rpsO RNA We have shown that the presence of the remainder of the acidic tail results in the thermodynamic stabilization of Hfq by 1.8 kcalÆmol)1 A comparison of the ... full-length protein Based on the analysis of the transition region, the conformational stability of the proteins can be calculated [29]: the free energy when Ó FEBS 2004 The role of the C-terminal domain ... noted that the C-terminal domain of Hfq seems to be located at the same position as that of the Sm-like SmAP3 of the archaea P aerophilum [31] and, as in the case of SmAP3, the possibility of two...

Ngày tải lên: 19/02/2014, 12:20

... destabilize the folded state The temperature of maximal stability in scHPr, Ts, was 292 K (Table 2) (the average of the values obtained at the different urea concentrations) The stability of scHPr ... any relationship between the presence of those states and the different conformational stability between the HPr species [32] Thus, the study of the stability among the different HPr members ... determine the cold-denaturation at this urea concentration were unsuccessful, probably because of the absence of enough data in the cold-denaturation region of the curve (Fig 5B) b The values of the thermodynamic...

Ngày tải lên: 19/02/2014, 12:20

... of wild-type ALP I On the other hand, the Tm of D266N/Y269A-ALP I increased by only °C The denaturation temperature indicates the stability of the structure of the protein The difference of the ... surrounding residues of the depression, and the side chain of the mutated residue might restrain the mobility of the N-terminal region on the surface by interaction with the main chain of Lys26 by van ... wildtype enzyme, the side chain of Asp266 interacted with the amino group of the main chain at Glu268 The oxygen of the main chain at Asp266 was bound to amino groups of main chain of Tyr269 and...

Ngày tải lên: 21/02/2014, 03:20

... This paper is based on the talk given at the Conference on Mathematics, Mechanics, and Informatics, Hanoi, 7/10/2006, on the occasion of 50th Anniversary of Department of Mathematics, Mechanics ... Tran Kim Thanh, On the characterization of the distribution of the composed random variables and their stabilities Dotor thesis, Hanoi 2000 [2] Tran Kim Thanh, Nguyen Huu Bao, On the geometric composed ... composed variables and the estimate of the stable degree of the Renyi’s characteristic theorem, Acta Mathemaica Vietnamica 21 (1996) 269 [3] C G Essen, Fourier analysis of distribution functions,...

Ngày tải lên: 14/03/2014, 13:20

... between the two proteins (as indicated by the values of DGwater, Cm and Tg) hence arise from the changes in the surface of the protein because of the interactions of the cofactor with the protein ... are comparable, the Tg values of the proteins vary slightly; there is a difference of almost C between the Tg values of the proteins, the value being higher for the holo form There have been ... conformational equilibrium between the two states [24,25] These two states have been identied as the major and the minor forms of the holoACP structure, on the basis of their percentage contributions...

Ngày tải lên: 16/03/2014, 10:20

... substrate to one of the two domains can also stabilize the structure of the other domain [32–34] Often the results of studies with the solubilized PGK not support the suggestion from the X-ray crystallographic ... not the clarification of the overall mechanism of thermal unfolding We have restricted ourselves to the question of whether unfolding of the two domains is (even slightly) separated Therefore, thermal ... favour of a highly co-operative thermal unfolding of the two domains in case of both enzyme forms, although the stabilities of the whole molecules differ from each other and from that of the wild-type...

Ngày tải lên: 16/03/2014, 18:20

... requires the occupation of the E2 state The severely impaired ADP-dependent dephosphorylation indicates that also the E1 state of the mutant differs from that of the wild-type Interestingly, the nearby ... plays a role in the transition between the states E1 and E2 Together with the recent determination of the crystal structure of the sarcoplasmic Ca-ATPase [4], analysis of these and other WD mutant ... enzymes The ATPase activity (percentage of the activity of the wild-type) present in membranes shown The ATPase activity present in the absence of zinc has been subtracted The concentration of zinc...

Ngày tải lên: 17/03/2014, 17:20

... District of Columbia has the TOC Chair and the Commonwealth of Virginia has the Vice Chair In April 2010, the Commonwealth of Virginia will assume the Chair and the State of Maryland will have the ... District of Columbia Department of Transportation, the Secretary of Transportation of the State of Maryland, and the Secretary of Transportation of the Commonwealth of Virginia This amendment provides ... completed at the end of 2012, FTA decided to add a new element to the scope of the audit: the effectiveness of the relationship between the SSO agency and the rail transit agency This audit of TOC,...

Ngày tải lên: 23/03/2014, 04:20

... that, unlike the wild-type, the C-terminal domain deleted KcsA cannot form tetramers in vivo Nevertheless, whether the lack of expression of the tetramer is caused by the absence of the tetramerization ... thermostabilities of the wild-type and mutant KcsA constructs were compared at basic and acidic pHs because the stability of KcsA depends on the pH of the solution: the tetrameric form of the wild-type ... control of the excitability of membrane, release of neurotransmitter, regulation of osmotic pressure and regulation of the size of cell) A structural and functional understanding of these channels...

Ngày tải lên: 23/03/2014, 06:20

... dependence of the heat capacity of the initial and final conformations (Cp,N2 and Cp,U), the heat capacity of the native state was taken to be a linear function of temperature and that of the unfolded state ... responsible for the higher stability of the wild-type protein compared to the mutant Thus, the value of 1.8 kJÆmol)1 could be taken as being the maximum cost of the disruption of the K13-E34 salt ... Nevertheless, there is no commonly held view in the literature on the energetic advantages of solvent-exposed salt bridges as the disruption of a salt bridge by the substitution of one of the...

Ngày tải lên: 23/03/2014, 12:20