splinting for patients with rheumatoid arthritis of the hands amp wrists

... treatment strategy of RA [7,8] Further, the disease course of RA is heterogeneous and about one-third of RA patients not experience joint damage [9,10] Thus, the identification of patients prone ... immunoglobulin; RA = rheumatoid arthritis; RF = rheumatoid arthritis Page of (page number not for citation purposes) Arthritis Research & Therapy Vol 11 No Bøyesen et al levels of anti-CCP, RF, ESR ... anti-resorptive treatment Further, there were no available specifications on the different DMARDs used during the five-year period The menopausal status of the patients was not known The DXR-BMD loss was...

Ngày tải lên: 09/08/2014, 14:22

... their content to the ICF and to appraise the currently available evidence of the quality of their measurement properties in order to offer recommendations for the use of PF scales for various purposes ... of searches was performed with the names of the retained questionnaires as search terms in addition to the words rheumatoid arthritis and references of included studies and studies citing the ... for PF, while factor analysis had indicated the presence of multiple dimensions Inappropriate statistical methods were used for the TFCQ, the sample size was < 50 patients for the MHIQ, and for...

Ngày tải lên: 12/08/2014, 00:20

... given the limited data Bentler’s CFI was 0.99 for the PRE module and 0.88 for the POST module; the NFI was 0.96 for the PRE module and 0.76 for the POST module; the RMSEA was 0.06 for the PRE ... conducted with a new group of patients Five patients with CD and five patients with RA took part in these cognitive debriefing interviews Six of these participants were female, and the mean age ... refinement of the SIAQv1.0 Patient data obtained with the POST module at the first SIV (SIV-1) were used for an exploratory factor analysis to evaluate the hypothetical structure of the SIAQv1.0...

Ngày tải lên: 20/06/2014, 15:20

... HRG contributed to the revision of the draft of the manuscript GDK contributed substantially to the conception and design of the project and to the revision of the draft of the manuscript All ... comparison of our results with those of other studies in RA and other conditions However, for the purpose of completeness, we have also analysed the data on the basis of other metabolic syndrome ... compared with NE (P = 0.026) The NCEP III cut off for hypertension was present in a significantly higher proportion of patients in the ME group (P = 0.027) but not in the LE group The other individual...

Ngày tải lên: 09/08/2014, 01:22

... determined by the duration of the inflammatory process The relation between the presence of rheumatoid factor and the frequency of the CD4+CD28– lymphocytes was evaluated A higher frequency of these ... populations of CD4+CD28– T cells [9] In patients with coronary artery disease, the frequency of these cells correlates with the risk of acute coronary syndromes [6] Such syndromes develop if the atheroscle- ... factor To examine whether the presence of large numbers of CD4+CD28– T cells in patients with RA is predictive of disease manifestation, the patients were allocated according to their disease pattern,...

Ngày tải lên: 09/08/2014, 01:22

... fluid of patients with RA [20] The presence of high levels of these soluble ligands in RA patients provides a basis for increased consumption of the sRAGE by interaction, followed by elimination of ... Radiographs of the hands and feet were obtained from all RA patients Criteria for the erosive disease were the presence of one or more bone erosions, defined as loss of cortical definition of the joint ... Thirty-nine patients out of 62 had erosive disease The presence of rheumatoid factor of any of the immunoglobulin isotypes was considered positive Thirty-eight patients had seropositive RA Data of patients...

Ngày tải lên: 09/08/2014, 06:23

... (10.8%) of the healthy controls included in the present study Three of these resulted in amino acid substitutions Nine (8.8%) of the RA patients from the present study exhibited five of these new ... padi4_96 The approach used therefore allowed a very detailed analysis of this part of the PADI4 gene that was implicated in influencing RA susceptibility Of these SNPs, the frequencies of padi4_89A→G, ... previously [8] These samples were analysed in our previous study for genetic variability of exons 2, 3, and of the PADI4 gene [8] Samples from 102 RA patients were enrolled to this study from the Department...

Ngày tải lên: 09/08/2014, 07:20

... Clinical characteristics of patients with rheumatoid arthritis and control subjects Patients with early rheumatoid arthritis (n = 89) Patients with long-standing rheumatoid arthritis (n = 66) Control ... gender with the entire group of RA patients and thus predictably did not exactly match with either the early or late RA groups Minor differences between the groups were dealt with by the use of multivariable ... concentrations and the calculation of low-density lipoprotein (LDL) RA measurements of disease activity and other outcomes In patients with RA, disease activity was measured with the use of the disease...

Ngày tải lên: 09/08/2014, 08:23

... meta-analysis [10,16,19] There have been a number of hypothesized explanations for the differences in the risk of certain malignancies in patients with RA compared with patients without the disease Possible ... risk of non-Hodgkin lymphoma in patients with rheumatoid arthritis compared with the general population CI, confidence interval; DMARDs, lymphoma in patients with rheumatoid arthritis compared with ... parity for the risk of overall malignancies (Figure 7) The random effects model provided a summary estimate of 1.05 (95% CI 1.01 to 1.09) Several of the studies examined the risk of malignancy in patients...

Ngày tải lên: 09/08/2014, 10:23

... satisfied the EULAR criteria for moderate or good response or ACR20 response criteria within weeks Similar to experience with other biologics for the treatment of RA patients, there was a subset of patients ... drawn, because of the small sample size (n = 6) of the cohorts treated with 0.3, 1, and mg/kg ACZ885 The onset of action in those who responded was found to be rapid The majority of these responders ... because of the skewness of the CRP measurements, the analysis was performed on the loge scale and results were back-transformed onto the original scale The inclusion of six patients per dose group...

Ngày tải lên: 09/08/2014, 10:23

... shown The relative band intensity is higher for the α-pGSN antibody for all of the SF samples and the plasma sample but much lower for the platelet lysate, which contains mainly the cGSN isoform ... present in synovial fluids of rheumatoid arthritis patients Various amounts of actin were detected in SFs of 77 of the 81 RA patients and in plasmas of 19 of the 78 patients by immunoblotting ... isoform This indicates the specificity of the α-pGSN antibody for the pGSN isoform and shows that the main isoform in SF is pGSN (n = 3; 24 SF samples were analyzed) RA, rheumatoid arthritis; rhpGSN,...

Ngày tải lên: 09/08/2014, 13:22

... HRG contributed to the revision of the draft of the manuscript GDK contributed substantially to the conception and design of the project and to the revision of the draft of the manuscript All ... comparison of our results with those of other studies in RA and other conditions However, for the purpose of completeness, we have also analysed the data on the basis of other metabolic syndrome ... compared with NE (P = 0.026) The NCEP III cut off for hypertension was present in a significantly higher proportion of patients in the ME group (P = 0.027) but not in the LE group The other individual...

Ngày tải lên: 09/08/2014, 13:22

... by the patients For older patients and those with poor eyesight, the responses were performed with the assistance of relatives who accompanied them and of rheumatology nurses at the clinics The ... correlation with all domains of the Thai HAQ These correlations emphasized the importance of function on the overall health status of patients with RA Floor and ceiling effects of the Thai HAQ ... (18.3%) in the North, 11 (8.7%) in the Northeast or East, and 31 (24.6%) in the Southern part of Thailand The mean (SD) age of the studied patients was 50.5 (13.0) years One hundred fourteen patients...

Ngày tải lên: 09/08/2014, 14:22

... the design and conduction of the study and drafted the manuscript PS participated in the design of the study, performed the statistical analysis of the data and drafted the manuscript GB performed ... cells in the PB and the bone marrow (BM) of rheumatoid arthritis (RA) patients (a) The percentage of PB (n = 11) CD19+ B cells was significantly reduced following months of treatment with rituximab ... specific effect of rituximab therapy To test whether B-cell depletion is specific to rituximab, we examined the effect of anti-TNF therapy on B cells in the PB of RA patients with active disease...

Ngày tải lên: 09/08/2014, 14:22

... in the MSUS assessment of the forefoot of patients with RA This work forms part of an ultrasound based research programme investigating the clinical relevance of soft tissue inflammation within ... MSUS2image of the plantar aspect of the right forefoot A MSUS image of the plantar aspect of the right forefoot The MSUS image demonstrates synovial thickening, joint effusion and bone changes within the ... relating to the sample should also be highlighted The sample was relatively small and comprised patients with severe disease therefore generalizibility to the whole population of patients with RA...

Ngày tải lên: 10/08/2014, 21:23

... in the monitoring of biologic therapy [14-16] The aim of this study was to evaluate by means of US, the effects of antiTNF therapy in RA patients with specific focus on the forefoot using the ... participated in the clinical assessment of foot status and drafted the manuscript CE participated in the design of the study, carried out the assessment of eligibility of RA patients for anti-TNF therapy ... relating to the sample and time frame also have to be highlighted The sample was relatively small; therefore generalizibility to the whole population of patients with RA needs to be confirmed The time...

Ngày tải lên: 10/08/2014, 21:24

... related to the foot include the presence and severity of disease activity in the foot joints, the presence and severity of structural foot deformities and the magnitude of pressure under the forefoot ... baseline (before the start of the intervention) and at final follow up (directly after the end of the intervention period) The intervention period consisted of one or more appointments with the podiatrist ... differences of rehabilitation intervention with their implications for required sample sizes using WOMAC and SF-36 quality of life measurement instruments in patients with osteoarthritis of the lower...

Ngày tải lên: 10/08/2014, 21:24

... treating these patients with anti-TNFα However, this treatment might be the best therapeutic option for their inflammatory disease Information regarding the safety of biologic agents prescribed to patients ... less than 5% of the patients Our statistical analysis plan therefore stipulated to perform a nested case control study as our main analysis of the risk of incident cancer For each case with an incident ... cancer), and the one patient under treatment with anakinra (lung cancer) died All other patients with recurrences were still alive at the time of the analysis Incidence of tumors in patients without...

Ngày tải lên: 12/08/2014, 11:22

... Nurmohamed MT: EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis Ann Rheum Dis 2010, 69:325-331 doi:10.1186/ar3186 ... as: Gonzalez-Gay MA, et al.: Role of carotid ultrasonography in the evaluation of cardiovascular risk in patients with rheumatoid arthritis Arthritis Research & Therapy 2010, 12:409 ... correlates with accelerated atherogenesis in patients with rheumatoid arthritis J Rheumatol 2005, 32:1219-1223 Gonzalez-Juanatey C, Llorca J, Martin J, Gonzalez-Gay MA: Carotid Page of intima-media...

Ngày tải lên: 12/08/2014, 15:22

... in the present study For a major proportion, 1,918 of the total of 2,419 patients known to the register, the year of RA diagnosis had been reported by the managing rheumatologist, or the patients ... age for all observed patients in the cohort at the start of each calendar year factor (TNF) inhibitors in the standard of care of patients with severe RA These agents were introduced in the late ... On the other hand, the precision of the estimates in the present study are limited due to the small sample size Finally, there was no decrease in the incidence of RA related TKA in Denmark in the...

Ngày tải lên: 12/08/2014, 15:23