... context of burden of disease and availability of effective interventions, treatment and management is crucial Yet often the capacity to carry out such planning and the appropriateness of tools ... structure to coordinate the work of a broad set of disciplines in assessing the safety, efficacy, effectiveness, costs and optimal use of technology in both populations and individual patients The ... inform the latter For HRH issues, the burden of illness might be measured in terms of shortages and unbalanced distributions of health workers Thus, the results of needs assessments can be used...
Ngày tải lên: 18/06/2014, 17:20
... Management and Law Michigan State University, East Lansing, Michigan, USA, Michel J G van Eeten, School of Technology, Policy and Management Delft University of Technology, Delft, The Netherlands and ... number of Internet users, the declining costs of storage and email access, widespread availability of malware tools, and a growing gap between the sophistication of systems and applications and ... the Financial Aspects of Network Security: Malware and Spam www.itu.int/ITU-D/cyb/cybersecurity/docs/itu-study-financial -aspects- of- malware -and- spam.pdf 3.3 The geography of malware and spam The...
Ngày tải lên: 14/02/2014, 08:20
Tài liệu Báo cáo khoa học: Crystal structures of a bacterial 6-phosphogluconate dehydrogenase reveal aspects of specificity, mechanism and mode of inhibition by analogues of high-energy reaction intermediates pdf
... key features of PDH specificity and mode of inhibition of the enzyme Results and Discussion Structural analysis and model quality Crystal structures of three different complexes of LlPDH have ... parameters (B-factors) and, where appropriate, the ligand occupancies Superposition of subunit A on B and C (468 Ca atoms) in complex II and III of LlPDH gives an rmsd of ˚ 1.6 A in each case, ... of B on C ˚ gives an rmsd of only 0.3 A We analysed this difference using the program dyndom [20] and identified a movement of the cofactor-binding domain of subunit A relative to subunits B and...
Ngày tải lên: 19/02/2014, 05:20
Tài liệu barriers to development of high technology small and medium sized enterprises potx
Ngày tải lên: 23/02/2014, 02:20
Báo cáo khoa học: Novel aspects of calmodulin target recognition and activation pptx
... recognition and activation (Eur J Biochem 270) 405 about 30 amino acids and consists of a helix-loop-helix where the two helices are arranged similar to the extended thumb and index finger of a hand: ... pentraxins, annexins and in C2 domains [36–39] The C2 domains consist of about 130 amino acids forming a compact b-sandwich composed of two four-stranded antiparallel b-sheets and bind up to three ... dominated by two EF-hand pairs forming the C- and N-terminal lobes and a long a-helix connecting the two lobes The two EF-hand pairs share 48% sequence identity and 75% sequence homology and the peptide...
Ngày tải lên: 17/03/2014, 09:20
health technology assessment and health policy making in europe potx
Ngày tải lên: 24/03/2014, 01:20
barriers to development of high technology small and medium sized enterprises docx
Ngày tải lên: 24/03/2014, 10:20
JOURNAL OF INDUSTRIAL TECHNOLOGY: Internet and Network Security docx
... firewalls, Journal of Industrial Technology proxies, and software, and (3) hardware – intelligent hubs, switches, and routers A network security policy, an auditing procedure, and a violation response ... made that all software are bug-free Understand Typical Network Functions Understanding how a network system normally functions, being aware of what is expected and unexpected, and knowing how ... confidentiality and secrecy (Sun Microsystems, 1999) Integrity Integrity includes the security of the network periphery, security of the network devices, and security of the flows of information...
Ngày tải lên: 28/03/2014, 22:20
Báo cáo khoa học: Functional aspects of the solution structure and dynamics of PAF – a highly-stable antifungal protein from Penicillium chrysogenum pdf
... charges of the adjacent Lys9 and Lys39 Similarly, Asp23 stabilizes the juxtaposed Lys15 and Lys17 side chains The hydrophobic strand b4 is located between Cys43 and Asp46 and, as a central strand of ... reduction of the protein activity (Fig 1B) accompanied by degradation of the protein (data not shown) Structure and dynamics of an antifungal protein Exposition of 104 conidiaÆmL)1 to lgÆmL)1 of PAF ... The 3D molecular structure of PAF consists of five b-strands connected by three small loops involving b-turn motifs (loops 1, and 4) and the large loop (Fig 9) The b-strands create two orthogonally...
Ngày tải lên: 29/03/2014, 23:20
Large-Scale Pyrolysis Oil Production: A Technology Assessment and Economic Analysis pptx
... environmental, safety, and health issues These issues are important to both the producer and consumer of bio-oils The producer must have a good understanding of the toxicity of bio-oil so as to design and ... Environmental, safety, and health issues For the bio-oil plant technical and economic analysis, the process is based on fast pyrolysis, which is composed of five major processing areas: feed handling and ... yields of liquid bio-oil 2) Reactor designs capable of meeting technical requirements 3) Bio-oil stability issues and recent findings that address the problem 4) Product specifications and standards...
Ngày tải lên: 01/04/2014, 00:20
Báo cáo hóa học: " Sargassum fusiforme fraction is a potent and specific inhibitor of HIV-1 fusion and reverse transcriptase" pot
... antiretroviral activity against both X4 and R5-tropic HIV-1, specificity of inhibition of viral fusion mediated against CD4 receptor, and post entry inhibition of the HIV-1 RT Compounds isolated from ... entry into cells consists of two distinct steps of 1) virus binding to the cellular receptor and coreceptor, which is followed by 2) fusion of the viral and cellular Page of (page number not for ... http://www.virologyj.com/content/5/1/8 Figure Inhibition of X4 and R5-tropic HIV-1 Inhibition of X4 and R5-tropic HIV-1 GHOST X4/R5 and GFP expressing cells were plate at × 105/well in 12-well plates and incubated at 37°C in...
Ngày tải lên: 20/06/2014, 01:20
Handbook of Reliability, Availability, Maintainability and Safety in Engineering Design - Part 84 docx
... degree 583 safety analysis 534, 537, 565 safety consequences 559 safety criticality 530 safety criticality analysis 650, 651, 654, 661 safety criticality rank 586 safety engineering 532 safety function ... 616, 634, 687, 694 logic and event symbols 546 safety and risk assessment 90 safety systems design 615 steps 88 FBC see feature-based costing FDQ see failure definition and quantification FEA see ... safety function 557, 558 safety intent specification 531 safety margin 20, 31, 67, 71, 72, 108, 416 safety protection system 616 safety risk 655 safety system 89, 688 safety systems design, cause-consequence...
Ngày tải lên: 02/07/2014, 10:20
Handbook of Reliability, Availability, Maintainability and Safety in Engineering Design - Part 1 docx
... Handbook of Reliability, Availability, Maintainability and Safety in Engineering Design Rudolph Frederick Stapelberg Handbook of Reliability, Availability, Maintainability and Safety in ... Such breadth is represented by the topics of reliability and performance, availability and maintainability, and safety and risk, in an overall concept of designing for integrity during the engineering ... examples of engineered installations that most of the problems stem from a lack of proper evaluation of their engineering integrity In determining the complexity and consequent frequent failure of...
Ngày tải lên: 02/07/2014, 10:20
Handbook of Reliability, Availability, Maintainability and Safety in Engineering Design - Part 2 docx
... List of Figures 1.1 1.2 1.3 Layout of the RAM analysis model 24 Layout of part of the OOP simulation model 25 Layout of the AIB blackboard ... diagram of a haul truck 53 Reliability of groups of series components 55 Example of two parallel components 56 Reliability of ... 4.49 4.50 4.51 List of Figures Propagation and mitigation strategy of the effect of uncertainties (Parkinson et al 1993) 436 Translation of a flowchart to a...
Ngày tải lên: 02/07/2014, 10:20
Handbook of Reliability, Availability, Maintainability and Safety in Engineering Design - Part 3 ppsx
... of inherent systems functions and their related equipment The integrity of engineering design therefore includes the design criteria of reliability, availability, maintainability and safety of ... control and instrumentation, incorrect spare parts lists, lack of proper identification of spares and facilities equipment such as manual valves and piping both on design drawings and on site, and ... and safety of these systems and equipment Reliability can be regarded as the probability of successful operation or performance of systems and their related equipment, with minimum risk of loss...
Ngày tải lên: 02/07/2014, 10:20
Handbook of Reliability, Availability, Maintainability and Safety in Engineering Design - Part 4 docx
... represented by the combined topics of reliability and performance, availability and maintainability, and safety and risk, in an overall concept of the integrity of engineering design—which has been ... and Safety The fundamental understanding of the concepts of reliability, availability and maintainability (and, to a large extent, an empirical understanding of safety) has in the main dealt with ... capabilities of the equipment In the case of MTBF and MTTR, there are no limits of capability Instead, prediction of the performance of equipment considers the effects of failure for each of the measures...
Ngày tải lên: 02/07/2014, 10:20
Handbook of Reliability, Availability, Maintainability and Safety in Engineering Design - Part 5 potx
... Assistance with and automation of complex tasks and activities of the design process where expertise is specialised and technical; • Strategies for searching in the space of alternative designs, and monitoring ... consideration of major design alternatives, and thus improves the quality of the result, the effectiveness of the design review process, and the integrity of the final design A class of AI tools ... understanding of the principles and philosophy of the use of artificial intelligence (AI) in engineering design, particularly in which new AI modelling techniques are applied, such as the inclusion of...
Ngày tải lên: 02/07/2014, 10:20
Handbook of Reliability, Availability, Maintainability and Safety in Engineering Design - Part 6 doc
... design integrity A basic and fundamental understanding of the concepts of reliability, availability and maintainability and, to a large extent, an empirical understanding of safety have in the main ... human safety factors into the design of complex engineering systems (Blandford et al 1999); R.L Pattison and J.D Andrews in their use of genetic algorithms in safety systems design (Pattison and Andrews ... Degree of automation of the application of design tool technology; Sophistication of general-purpose tools (shells); Degree of usage in engineering design organisations; Degree of understanding of...
Ngày tải lên: 02/07/2014, 10:20
Handbook of Reliability, Availability, Maintainability and Safety in Engineering Design - Part 7 docx
... distinction, and indicate significant differences in the approaches to determining the reliability of systems, compared to that of assemblies or of components They start from a prediction of reliability of ... estimation of reliability based on inferences of failure of equipment according to their statistical failure distributions (reliability assessment) and, finally, to a determination of reliability ... emphasised the consequences of unreliability of systems The consequences of systems unreliability ranged from operator safety to economic consequences of systems failure and, on a broader scale,...
Ngày tải lên: 02/07/2014, 10:20
Handbook of Reliability, Availability, Maintainability and Safety in Engineering Design - Part 8 doc
... optimum level of process reliability (and safety) However, this is misleading, as the prediction of process reliability and the inherent probability of failure not reflect reality precisely, and the ... some of the critical assemblies and components Consider the overall reliability of these sub- 3.2 Theoretical Overview of Reliability and Performance in Engineering Design 57 Reliability of N ... Probability of failure × Consequence of failure This probability and consequence of systems failure is related to process reliability and criticality at the higher systems levels (i.e process and system...
Ngày tải lên: 02/07/2014, 10:20