small cell lung cancer symptoms and signs

... J Cancer 2001, 94:153-156. 2. Non -small Cell Lung Cancer Collaborative Group: Chemotherapy in non small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomized ... Tonato M: Gemcitabine and cisplatin versus mito- mycin, ifosfamide, and cisplatin in advanced non -small- cell lung cancer: a randomized phase III study of the Italian Lung Cancer Project. J Clin ... sur- vival and improve quality of life in non -small cell lung cancer: a review of the literature and future directions. Clin Cancer Res 1998, 4:1087-1100. 4. Le Chevalier T, Brisgand D, Douillard...

Ngày tải lên: 18/06/2014, 15:20

... stage small cell lung cancer. Int J Radiat Oncol Biol Phys 1999, 43:39-45. 31. Rancati T, Ceresoli GL, Gagliardi G, Schipani S, Cattaneo GM: Factors predicting radiation pneumonitis in lung cancer ... locally advanced non -small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy Anhui Shi, Guangying Zhu*, Hao Wu, Rong Yu, Fuhai Li and Bo Xu Abstract Background: ... dosimetric factors and severe acute radiation pneumonitis (SARP) in patients with locally advanced non -small cell lung cancer (LANSCLC) treated with concurrent chemotherapy and intensity-modulated...

Ngày tải lên: 09/08/2014, 08:23

Ngày tải lên: 09/08/2014, 10:21

Ngày tải lên: 10/08/2014, 10:21

Ngày tải lên: 10/08/2014, 10:21

Ngày tải lên: 10/08/2014, 10:21

Ngày tải lên: 10/08/2014, 10:21

Ngày tải lên: 11/08/2014, 08:21

Ngày tải lên: 11/08/2014, 12:20

Ngày tải lên: 12/08/2014, 18:21

... mutations in lung cancer patients. Methods: EGFR mutation status was analyzed by DNA assays, and compared with IHC results in five non -small- cell lung cancer (NSCLC) cell lines and tumor samples ... Non -small- cell lung cancer harbouring mutations in the EGFR kinase domain. Clin Transl Oncol 2010, 12:75-80. 9. Gazdar AF: Activating and resistance mutations of EGFR in non -small- cell lung cancer: ... analyses [10,11]. Methods Sources of cell lines and culture The PC-9 lung tumor cell line was kindly provided by Roche (Basel, Switzerland); the A549 and H460 cell lines were purchased from the...

Ngày tải lên: 18/06/2014, 16:20

... and for clinical-pathological reasons are often divided into two broad categories: small cell lung cancer (SCLC) and non -small cell lung cancer (NSCLC). All major histological types of lung cancer ... oesophagus, head and neck cancer. HPV has also been speculated to have a role in the pathogenesis of lung cancer. To validate the hypothesis of HPV involvement in small cell lung cancer pathogenesis ... pathogenesis of lung cancer. Annu Rev Physiol 2002, 64:681-708. 13. Syrianen KJ: HPV infections and lung cancer. J Clin Pathol 2002, 55:885-891. 14. zur Hausen H: Papillomaviruses and cancer: from...

Ngày tải lên: 18/06/2014, 16:20

... tumor cells versus stromal cells in non small cell lung cancer. Clin Cancer Res 2007, 13:6649-57. 24. World Health Organization: Histological Typing of Lung and Pleural Tumours. Geneva, Switzerland: ... isoforms, PTEN and PI3K in tumor epithelial cells and stromal compartment in non -small cell lung cancer. Anticancer Res 2009, 29:4175-83. 28. Al-Saad S, Al-Shibli K, Donnem T, Andersen S, Bremnes ... histology. Lung Cancer 2010. 31. Donnem T, Al-Saad S, Al-Shibli K, Andersen S, Busund LT, Bremnes RM: Prognostic impact of platelet-derived growth factors in non -small cell lung cancer tumor and stromal...

Ngày tải lên: 18/06/2014, 16:20

... Staging of small cell and non -small cell lung cancer. University of Iowa Virtual Hos- pital; 1999. 6. Hopwood P, Stephens RJ: Symptoms at presentation for treat- ment in patients with lung cancer: ... the most life-threatening form of cancer in Scot- land [2]. Lung cancer is also a major cause of death throughout the rest of the world [3,4]. Non -small cell lung cancer (NSCLC) has a poor progno- sis. ... disease progression and severe toxicities in NSCLC. Background In 2002, approximately 29,000 people died from lung cancer in England and Wales[1] and it is the most com- mon and the most life-threatening...

Ngày tải lên: 18/06/2014, 19:20

... Lung cancer is one of the most common human cancers and the leading cause of cancer death world- wide (1). Lung cancer is generally classified into two histological types, small cell lung cancer ... gefitinib in non -small cell lung cancer cell lines. Mol Cancer Res. 2006; 4(8): 521-8. 102. Taguchi F, Solomon B, Gregorc V, et al. Mass spectrometry to classify non -small- cell lung cancer patients ... factor receptor and non -small- cell lung cancer. J Med Genet. 2007; 44(3): 166-72. 41. Riely GJ, Pao W, Pham D, et al. Clinical course of patients with non -small cell lung cancer and epidermal...

Ngày tải lên: 08/08/2014, 17:20

... by first-line chemotherapy with single agent docetaxel in a patient with advanced non small cell lung cancer Ferdinando Riccardi 1* , Giuseppe Di Lorenzo 1 , Carlo Buonerba 1 , Guglielmo Monaco 2 , ... treatment. Introduction In non -small cell lung cancer (NSCLC), mediastinal lymphnode involvement comprises a wide spectrum of severity. In fact, while 9% of patients with IIIA-N2 NSCLC is candidate for surgery ... Carteni’ 1 Abstract Background: Defining the optimal treatment for patients with inoperable non small cell lung cancer (NSCLC), presenting with metastatic mediastinal lymph nodes, is challenging. Nevertheless,...

Ngày tải lên: 09/08/2014, 03:21

... non -small cell lung cancer. Lung Cancer 2003, 41:1-11. 17. Shibamoto Y, Yukawa Y, Tsutsui K, Takahashi M, Abe M: Variation in the hypoxic fraction among mouse tumors of different types, sizes, and sites. ... non -small- cell lung cancer: clinical implications. Radiother Oncol 2010, 94:1-11. 27. Chen Y, Guo W, Lu Y, Zou B: Dose-individualized stereotactic body radiotherapy for T1-3N0 non -small cell lung ... (SBRT) for lung t umors wasintroducedinthemid1990s[1],andithasbeen performed in many institutions as a new treatment modality for stage I primary lung cancer and oligometa- static lung cancer. Promising...

Ngày tải lên: 09/08/2014, 09:20

... properties, and morphological characteristics of permanent human small cell lung cancer cell lines. J Cancer Res Clin Oncol 1987, 113:31-40. 16. NCCN guidelines for small- cell lung cancer. [http://www.nccn.org/ professionals/physician_gls/f_guidelines.asp]. 17. ... limited-stage small- cell lung cancer. Int J Radiat Oncol Biol Phys 2003, 56:355-359. 5. Roof KS, Fidias P, Lynch TJ, Choi NC: Radiation dose escalation in limited- stage small- cell lung cancer. Int ... in limited-stage small cell lung cancer: facts, questions, prospects. Radiother Oncol 2000, 55:1-9. 2. Murray N, Turrisi AT: A review of first-line treatment for small- cell lung cancer. J Thorac...

Ngày tải lên: 09/08/2014, 09:20

... Stereotactic Body Rad iotherapy, Oligometastases, Non -Small Cell Lung Cancer Background Non -small cell lung cancer (NSCLC) is the leading cause of cancer mortality in the United States [1]. Patients ... limited stage IV non -small cell lung cancer Praveena Cheruvu 1 , Su K Metcalfe 1 , Justin Metcalfe 1 , Yuhchyau Chen 1 , Paul Okunieff 2 and Michael T Milano 1* Abstract Background: Standard therapy ... Milano 1* Abstract Background: Standard therapy for metastatic non small cell lung cancer (NSCLC) includes palliative systemic chemotherapy and/ or radiotherapy. Recent studies of patients with limited...

Ngày tải lên: 09/08/2014, 09:20

... surgery in patients with operable lung cancer. A randomized phase III trial of Radiosurgery Or Surgery for operable Early stage (stage 1A) non -small cell Lung cancer (ROSEL, ClinicalTrials.gov ... and the Dutch Lung Cancer Research Group. The primary study objectives are to compare local and regional control, qual- ity of life and treatment costs at 2 and 5 years in patients who are randomized ... Therefore, an additional planning study was performed in 22 stage IA and 4 stage 1B non -small cell lung cancer patients in order to develop and evaluate the planning guidelines differentiated according...

Ngày tải lên: 09/08/2014, 09:22