small cell lung cancer survivors

... Evalution of surface-based deformable image registration for adaptive radiotherapy of non-small cell lung cancer (NSCLC) Matthias Guckenberger*, Kurt Baier, Anne Richter, Juergen Wilbert and Michael ... performance of surface-based deformable image registration (DR) for adaptive radiotherapy of non-small cell lung cancer (NSCLC) Methods: Based on 13 patients with locally advanced NSCLC, CT images acquired ... relationship between the target and the parotid glands [8] Similar findings were made for non-small-cell lung cancer (NSCLC), where a continuous tumor regression during radiotherapy was observed [9]

Ngày tải lên: 09/08/2014, 10:20

... 157,300 deaths from lung cancer [4]. Lung cancer has traditionally been dichotomized into two groups based on the histological features of the tumor: small cell and non-small cell lung cancer. NSCLC ... non-small cell lung cancer comprise the majority of cases annotated within the database. Other cancers contained in the database include small cell lung cancer, mesothelioma, esophageal cancer, ... this article as: Surati et al.: Proteomic characterization of non-small cell lung cancer. .. cell lung cancer in a comprehensive translational thoracic oncology database

Ngày tải lên: 10/08/2014, 09:22

... levels in normal lung tissues, and nonsmall cell lung cancers. Jpn J Cancer Res 1999, 90:1338-43. 11. Tsujii M, Kawano S, DuBois RN: Cyclooxygenase-2 expression in human colon cancer cells increases ... protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner. Cancer Res 2005, 65(14):6275-81. 24. Kang ... prognosis and short survival of lung cancer patients [7]. However, although altered COX -2 activity is associated with malignant progression in non-small cell lung cancer (NSCLC), the intrinsic

Ngày tải lên: 10/08/2014, 10:20

... Clinical Cancer Research 2011, 30:20 http://www.jeccr.com/content/30/1/20 RESEARCH Open Access Upregulation of microRNA-451 increases cisplatin sensitivity of non-small cell lung cancer cell line ... sensitivity of non-small cell lung cancer (NSCLC) cells to cisplatin (DDP) remains unclear The aim of this study is to evaluate the roles of miR-451 in the sensitivity of NSCLC cells to DDP Methods: ... Maintenance chemotherapy in non-small cell lung cancer J Natl Compr Canc Netw 2010, 8:815-821 Kostova I: Platinum complexes as anticancer agents Recent Pat Anticancer Drug Discov 2006, 1:1-22

Ngày tải lên: 10/08/2014, 10:21

... non small -cell lung cancer Clin Lung Cancer... subgroup analysis of tribute, a phase III trial of erlotinib plus carboplatin and paclitaxel in non-small cell lung cancer Clin Cancer ... non-small cell lung cancer Clin Cancer Res 2006, 12:3078-3084 Aviel-Ronen S, Blackhall FH, Shepherd FA, Tsao MS: K-ras mutations in non-small- cell lung carcinoma: a review Clin Lung ... estimated 29% of all cancer deaths [1]. World-wide, the impact of lung cancer is enor- mous, with 1.35 million cases and approximately 1.18 million deaths [2]. Non-small cell lung cancer (NSCLC),

Ngày tải lên: 10/08/2014, 22:20

... several key studies in non-small-cell lung cancer (NSCLC) The purpose of this article is to review several important abstracts that were presented in different lung cancer tracts, which may influence ... Mirshahidi* and Chung T Hsueh Abstract We have reviewed the pivotal presentations in non-small cell lung cancer (NSCLC) from the 2009 annual meeting of the American Society of Clinical Oncology ... http://www.jhoonline.org/content/3/1/18 JOURNAL OF HEMATOLOGY & ONCOLOGY Open Access REVIEW Updates in non-small cell lung cancer - insights from the 2009 45th annual meeting of the American Society of Clinical

Ngày tải lên: 10/08/2014, 22:21

... included mixed groups of patients with primary small or non-small cell lung cancer (NSCLC) and lung metastases, and did not compare VOC levels in lung cancer patients with those in asymptomatic smokers ... Zylak C: THE LUNG SCREENING STUDY RESEARCH GROUP. Final results of the Lung Screening Study, a randomized feasibility study of spiral CT versus chest X-ray screening for lung cancer. Lung Cancer 2005, ... Respiratory Research Open Access Research Exhaled volatile organic compounds in patients with non-small cell lung cancer: cross sectional and nested short-term follow-up study Diana Poli 1,2 , Paolo Carbognani

Ngày tải lên: 12/08/2014, 18:21

... Calpha in non-small-cell lung cancer Clin Lung Cancer 2004, 6:184-189 Brognard J, Dennis PA: Variable apoptotic response of NSCLC cells to inhibition of the MEK/ERK pathway by small molecules ... mitotic catastrophe in non-small cell lung cancer cells Int J Cancer 2006, 119:1028-1038 Adjei AA, Hidalgo M: Intracellular signal transduction pathway proteins as targets for cancer therapy J Clin ... of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung Cancer Res 1993, 53:2379-2385 Price JT, Wilson HM, Haites NE: Epidermal

Ngày tải lên: 13/08/2014, 16:21

... receptordouble stranded RNAsmall interference RNAnon small cell lung cancer Abstract Lung cancer has emerged as a leading cause of cancer death in the world. Non-small cell lung cancer (NSCLC) accounts ... purposes) Background Lung cancer is a leading cause of cancer death in Australia and the world [1,2]. There are two types of lung cancers, non small cell (NSCLC) and small cell (SCLC). NSCLC accounts ... tyrosine kinase inhibitors in cancer therapy Cancer Cell 2002, 1:117-123 Baselga J: The EGFR as a target for anticancer therapy – focus on cetuximab Eur J Cancer 2001, 37:S16-22 Tamm

Ngày tải lên: 14/08/2014, 19:22

... Facts: Non-Small-Cell Lung Cancer T cell receptor Antigen T cell OFF PD-1 Tumor cell PD-L1 Tumor cell T cell ON Anti-PD-1 Anti-PD-L1 Figure 5.1 Tumor cells can present antigen to activated T cells ... PD-1 is an inhibitory cell-surface receptor that is expressed on activated T cells, B cells, natural killer cells, monocytes and dendritic cells The effector function of T cells that express PD-1 ... T cells Upon T cell activation, programmed cell death (PD-1) receptors are expressed on T cells When coupled to the programmed cell death ligand (PD-L1) receptor on the tumor cell, the normal

Ngày tải lên: 21/01/2020, 11:49

... Non-small-cell lung cancer (NSCLC), which includes adenocarcinoma, squamous cell carcinoma and large cell carcinoma, accounts for approximately 80–85% of all lung cancers Small-cell lung cancer ... stage I non-small cell lung carcinoma Oncol Rev 2014;8:234–41 11 Ginsberg RJ, Rubinstein LV Randomized trial of lobectomy versus limited resection for T1 N0 non-small cell lung cancer Lung Cancer ... patients with lung cancer Thorax 2010;65 Suppl 3:iii1–27 Howington JA, Blum MG, Chang AC et al Treatment of stage I and II non-small cell lung cancer: diagnosis and management of lung cancer, 3rd

Ngày tải lên: 23/01/2020, 14:49

... survival rate Keywords: Immunoassay, Early stage lung cancer, Detection, Biomarkers, Proteomics, Diagnostic tests, Non-small cell lung cancer Background Lung cancer is a pervasive disease that is commonly ... rate; FPR: False positive rate; LC: Lung cancer; LCDT1: Lung cancer detector test 1; LDCT: Low-dose spiral computed tomography; NSCLC: Non-small cell lung cancer; PET: Positron emission tomography; ... American Cancer Society predicts about 228,150 new cases and 142,670 deaths for 2019 in the United States On average, 422 Americans die every day of lung cancer (LC) Non-small Cell Lung Cancer

Ngày tải lên: 17/06/2020, 03:04

... metastatic non-small cell lung cancer: are patients undertreated? Cancer 2015;121(15):2562–9 https://doi.org/10.1002/cncr 29386 38 Scarpace SL Metastatic squamous cell non-small-cell lung cancer (NSCLC): ... Akerley W, Bepler G, et al Non-small cell lung cancer J Natl Compr Cancer Netw 2010;8(7):740–801 Gaughan EM, Costa DB Genotype-driven therapies for non-small cell lung cancer: focus on EGFR, KRAS ... latest mortality projections, lung cancer agestandardized mortality rate will surpass breast cancer mortality rate before 2030 in many countries [3] Nonsmall cell lung cancer (NSCLC) accounts for

Ngày tải lên: 17/06/2020, 11:28

... critical to non- T small cell lung cancer Cancer Lett 2018;434:132–43 Asamura H, Chansky K, Crowley J, et al The International Association for the Study of Lung Cancer lung Cancer staging project: ... stated in a credit line to the data Xu et al BMC Cancer (2020) 20:262 Background Non-small cell lung cancer (NSCLC) is the most common type of lung cancer Chemotherapy and radiotherapy, have reached ... role in cancer cell migration and invasion by repressing TP63 expression in breast and kidney cancer cells [7] Increased CHD4 expression has also been detected in ovarian and oral cancer cells

Ngày tải lên: 17/06/2020, 11:36

... Keywords: Locally advanced, Non-small-cell lung cancer, ECOG 2, Chemoradiotherapy, Efficacy, Toxicity Background Non-small-cell lung cancer (NSCLC) accounts for 85% of all lung cancers [1], and approximately ... Abbreviations ECOG: Eastern Cooperative Oncology Group; NSCLC: Non-small-cell lung cancer; LA-NSCLC: locally advanced non-small-cell lung cancer; CCRT: Concurrent chemoradiotherapy; 3D-CRT: three-dimensional ... locally advanced nonsmall-cell lung cancer J Clin Oncol 2010;28(13):2181–90 Lilenbaum RC, Cashy J, Hensing TA, Young S, Cella D Prevalence of poor performance status in lung cancer patients: implications

Ngày tải lên: 17/06/2020, 11:38

... afatinib in patients with advanced non-small-cell lung cancer harbouring uncommon EGFR mutations: a combined post-hoc analysis of LUX-lung 2, LUX-lung 3, and LUX-lung Lancet Oncol 2015;16(7):830–8 ... Yamaguchi T, et al Gefitinib in patients with brain metastases from non-small-cell lung cancer: review of 15 clinical cases Clin Lung Cancer 2004;6(2):123–8 Porta R, Sanchez-Torres JM, Paz-Ares L, Massuti ... receptor tyrosine kinase inhibitors for brain metastasis in non-small cell lung cancer patients harboring either exon 19 or 21 mutation Lung Cancer 2012;77(3):556–60 Wu YL, Zhou C, Cheng Y, Lu S, Chen

Ngày tải lên: 17/06/2020, 18:13

... chemotherapy for PD-L1-positive non-small-cell lung Cancer N Engl J Med 2016;375(19):1823–33 Remon J, Vilarino N, Reguart N Immune checkpoint inhibitors in non-small cell lung cancer (NSCLC): approaches ... Genomic features of response to combination immunotherapy in patients with advanced nonsmall-cell lung Cancer Cancer Cell 2018;33(5):843–52 e844 Brody R, Zhang Y, Ballas M, Siddiqui MK, Gupta P, Barker ... Combination therapy of radiotherapy and anti-PD-1/PD-L1 treatment in nonsmall-cell lung Cancer: a mini-review Clin Lung Cancer 2018;19(1):12–6 Adams DL, Adams DK, He J, Kalhor N, Zhang M, Xu T,

Ngày tải lên: 17/06/2020, 18:37

... anticancer activity of DS and DDC In contrast, modification of the ethyl groups had no significant effect on their anticancer activity Methods Cell line and reagents The non-small cell lung cancer ... path for translation of DS into cancer therapeutics Keywords: Disulfiram, Cancer stem cells, Copper, Non-small cell lung cancer, Reactive oxygen species, Diethyldithiocarbamate, S-methyl-diethyldithiocarbamate ... pathways [13] It eradicates cancer stem cells (CSCs) and significantly reverses chemoresistance in resistant cancer cell lines [9–11, 13] Its cytotoxicity in cancer cells is copper dependent [8,

Ngày tải lên: 03/07/2020, 01:05

... the most common tumor type [1] Small cell lung cancer (SCLC) accounts for approximately 15% of new cases of annually diagnosed lung cancer, and up to 25% of lung cancer deaths each year [2] Approximately ... platinum easier Keywords: Small cell lung cancer, Extensive-staged, Irinotecan, Etoposide, Meta-analysis Background Lung cancer, which represents 13% of newly diagnosed cancers worldwide, is the ... databases were used to perform an electronic search by combining following words: “small cell lung cancer” or “small cell lung carcinoma,” “irinotecan” or “CPT-11,” and “etoposide” or “VP-16” To limit

Ngày tải lên: 03/07/2020, 01:36

... in non-small cell lung cancer cells by promoting ubiquitin-proteasomal degradation via inhibition of the Raf-MEK-ERK (Raf/mitogen-activated extracellular signal-regulated kinase/extracellular ... subtypes and at a cancer progression stage (e.g SCC tumors infected with BLV, PlpPV1, and STLV, and metastatic lung cancer with Y73SV, and primary NSCLC with HTLV-1) The cell types of lung cancer have ... Magliocco G, Thissen JB, Antonia S Molecular evidence of viral DNA in non-small cell lung cancer and non-neoplastic lung Br J Cancer 2016; 115(4):497–504 Hasegawa Y, Ando M, Kubo A, Isa S, Yamamoto

Ngày tải lên: 03/07/2020, 01:48