small cell lung cancer stage 1
Báo cáo hóa học: " Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer" pdf
... 29 Histology adeno 69 61 57 217 60 SCC 1 0 7 11 2 0 LCC 5 0 4 11 0 others 3 0 2 0 0 EGFR exon 19 29 10 18 21 55 58 21 exon 21 27 0 12 14 18 56 23 wild-type 22 51 29 296 14 5 16 7 16 IHC sensitivity overall ... sequencing EGFR EXON 19 DELETION SUBTYPE 0 1+ 2+ 3+ 15 bp N =17 0 /17 (0%) 0 /17 (0%) 2 /17 (11 %) 15 /17 (89%) 9bp N=4 2/4 (50%) 2/4(50%) 0/4 (0%) 0/4 (0%) 12 bp N =1 1 /1 (10 0%) 0 /1 (0%) 0 /1 (0%) 0 /1 (0%) 18 bp N=5 4/5 ... bp N=5 4/5 (80%) 1/ 5 (20%) 0/5 (0%) 0/5 (0%) 21 bp N =1 1 /1 (10 0%) 0 /1 (0%) 0 /1 (0%) 0 /1 (0%) 24 bp N =1 1 /1 (10 0%) 0 /1 (0%) 0 /1 (0%) 0 /1 (0%) Figure 2 IHC staining of tumor samples from lung cancer patients....
Ngày tải lên: 18/06/2014, 16:20
Báo cáo khoa học: "Clinical outcomes of stereotactic body radiotherapy for stage I non-small cell lung cancer using different doses depending on tumor size" ppsx
... (78) Gender Male 84 1 54 29 Female 40 1 31 8 Performance status 0 65 2 47 16 1 48 0 31 17 211 074 Tumor size (mm) Range (median) 12 -55 (27) 12 , 14 15 -34 (24) 31- 55 (35) Operability Operable 40 2 27 11 Non-operable ... 46 18 Squamous cell carcinoma 35 0 19 16 Unclassified NSCLC 13 0 10 3 Unproven 10 0 10 0 Tumor location Central 29 0 18 11 Peripheral 95 2 67 26 Abbreviations: NSCLC = non -small cell lung cancer. Baba ... early- stage non -small- cell lung cancer: clinical implications. Radiother Oncol 2 010 , 94 :1- 11. 27. Chen Y, Guo W, Lu Y, Zou B: Dose-individualized stereotactic body radiotherapy for T1-3N0 non-small...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: "The effect of bioequivalent radiation dose on survival of patients with limited-stage small-cell lung cancer" pdf
... interests. Received: 16 January 2 011 Accepted: 19 May 2 011 Published: 19 May 2 011 References 1. De Ruysscher D, Vansteenkiste J: Chest radiotherapy in limited -stage small cell lung cancer: facts, questions, ... 0. 713 Male 57( 81. 4)* 10 7(79.3) Female 13 (18 .6) 28(20.7) KPS Median 80 80 0 .16 3 Range 60 -10 0 60 -10 0 Weight loss>5% 0 .17 8 Yes 21( 30.0) 29( 21. 5) No 49(70.0) 10 6(78.5) LDH 0. 517 ≤220 IU/L 35(43 .1) ... radiation dose and fractionation on outcomes for limited -stage small- cell lung cancer. Int J Radiat Oncol Biol Phys 2 010 , 76 :11 21- 112 6. 18 . Schild SE, Bonner JA, Hillman S, Kozelsky TF, Vigliotti...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: " Comparison of outcomes in patients with stage III versus limited stage IV non-small cell lung cancer" docx
... manuscript. Received: 4 April 2 011 Accepted: 30 June 2 011 Published: 30 June 2 011 References 1. Jemal A, Siegel R, Xu J, Ward E: Cancer Statistics, 2 010 . CA Cancer J Clin 2 010 , 60(5):277-300, Epub 2 010 Jul 7. 2. ... Oligometastases, Non -Small Cell Lung Cancer Background Non -small cell lung cancer (NSCLC) is the leading cause of cancer mortality in the United States [1] . Patients with stage IV NSCLC typically ... 6:80 http://www.ro-journal.com/content/6 /1/ 80 Page 2 of 7 RESEARC H Open Access Comparison of outcomes in patients with stage III versus limited stage IV non -small cell lung cancer Praveena Cheruvu 1 , Su K Metcalfe 1 , Justin...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: "Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study" pps
... None Minor < ;1. 15 1. 15 1. 25 <8 8 10 <55 55–60 <4 4–6 0–20 < ;1. 15 1. 15 1. 25 <7 7–8 <65 65–70 <6 6–8 20–40 < ;1. 10 1. 10 1. 20 <6 6–6.5 <65 65–75 <8 8 10 >40 Type ... < ;12 12 14 <65 65–75 <5 5–8 0–20 < ;1. 15 1. 15 1. 25 <9 9 11 <70 70–80 <6 6 10 20–40 < ;1. 10 1. 10 1. 20 <6 6–8 <70 70–80 < ;10 10 15 >40 ... PTV (R 10 0% ) from a total of 22 patients with stage IA tumours and 4 patients with stage 1B tumours (with PTVs of 59 cc, 85 cc, 10 7 cc and 10 8 cc). 0 25 50 75 10 0 12 5 0.9 1. 0 1. 1 1. 2 1. 3 1. 4 ...
Ngày tải lên: 09/08/2014, 09:22
Báo cáo khoa học: " Stereotactic, single-dose irradiation of stage I non-small cell lung cancer and lung metastases" docx
Ngày tải lên: 09/08/2014, 10:21
báo cáo hóa học:" Randomized phase II study with two gemcitabine- and docetaxel-based combinations as first-line chemotherapy for metastatic non-small cell lung cancer" docx
... carcinoma 14 (35) 12 (29.3) Other NSCLC 4 (10 ) 6 (14 .6) Site of disease Lung ± lymph nodes 14 (35) 14 (34 .1) Lung and 1 metastatic site 12 (30) 15 (36.6) Lung and ≥ 2 metastatic sites 9 (22.5) 10 (24.4) Extra-pulmonary ... (%) Leukopenia 6 (15 ) 9 (23) 4 (10 ) 3 (8) 2 (5) 2 (5) Anemia 12 ( 31) 1 (3) 0 - 5 (13 ) 0 - 0 - Thrombocytopenia 1 (3) 2 (5) 0 - 2 (5) 0 - 0 - Neutropenia 3 (8) 7 (18 ) 14 * (36) 6 (16 ) 4 (11 ) 7 † (8) Non ... patients with advanced non -small- cell lung cancer. The European Organi- zation for Research and Treatment of Cancer Lung Cancer Cooperative Group. J Clin Oncol 19 98, 16 : 213 3- 214 1. 7. Crino L, Scagliotti...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: "Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins" ppt
... colorectal cancer. BMC Cancer 2 010 , 26 ;10 :11 7. 31. Marur S, D’Souza G, Westra WH, Forastiere AA: HPV-associated head and neck cancer: a virus-related cancer epidemic. Lancet Oncol 2 010 , 11 :7 81- 789. 32. ... from human normal lung, (GSM14 018 5-GSM14 018 9), and five sets from human SCLC, (GSM14 017 6-GSM14 018 0) [20] and analyzed data set s with GeneSpring 10 . Of the 8793 genes exam- ined, 5 61 were differentially ... 55% had HPV16 /18 DNA compared with 11 % of non cancer control subje cts. Additionally HPV 16 /18 DNA has been uniformly detected in lung tumor cells but not in the adjacent noninvolved lung tissue...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: "Prognostic Impact of MiR-155 in Non-Small Cell Lung Cancer Evaluated by in Situ Hybridization" pot
... 71 II 13 6 41 61 51 IIIa 42 12 17 23 Tumor status <0.0 01 1 85 25 19 0 74 2 18 8 56 84 57 36 219 2536 Nodal status <0.0 01 0 232 69 19 0 66 17 6233543 2 27 8 18 18 Surgical margins 0.29 Free 307 92 19 0 ... 63 ECOG 1 120 36 64 52 ECOG 2 18 5 25 33 Weight loss 0. 71 < ;10 % 303 90 12 7 58 > ;10 % 32 10 98 57 Histology 0.028 SCC 19 1 57 NR 66 Adenocarcinoma 95 34 47 41 LCC 31 9 98 56 BAC 18 NR 71 Differentiation ... <0.0 01 Poor 13 8 41 47 47 Moderate 14 4 43 19 0 64 Well 53 16 NR 68 Surgical procedure 0.004 Lobectomy + Wedge* 243 73 19 0 61 Pneumonectomy 92 27 37 47 Pathological stage <0.0 01 I 15 7 47 19 0 71 II...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " Health state utilities for non small cell lung cancer" pot
... 9.8% Student 15 .0% 1. 9% Other 11 .0% 2.3% Education – leaving age No Formal Qualifications 8.0% - GCSE/O Levels (16 yrs) 17 .0% - A Levels (18 yrs) 26.0% - Vocational or work based 11 .0% - University ... advanced non -small cell lung cancer: descriptive study based on scripted interviews. BMJ 19 98, 317 :7 71- 5. 13 . Socinski MA, Morris DE, Masters GA, Lilenbaum R: Chemothera- peutic management of stage ... 0. 016 33 99 -5. 51 <0.00 01 Fatigue -0.07346 0. 018 49 99 -3.97 0.00 01 Nausea & vomiting -0.04802 0. 016 18 99 -2.97 0.0038 Diarrhoea -0.0468 0. 015 53 99 -3. 01 0.0033 Hair loss -0.04495 0. 014 82 99 -3.03...
Ngày tải lên: 18/06/2014, 19:20
Báo cáo toán học: "Molecular Predictors of EGFR-TKI Sensitivity in Advanced Non–small Cell Lung Cancer" ppsx
... 20 01; 18 (6): 10 59-68. 3. Travis WD, Travis LB, Devesa SS. Lung cancer. Cancer. 19 95; 75 (1 Suppl): 19 1-202. 4. Franceschi S, Bidoli E. The epidemiology of lung cancer. Ann Oncol. 19 99; 10 ... gefitinib in non -small cell lung cancer cell lines. Mol Cancer Res. 2006; 4(8): 5 21- 8. 10 2. Taguchi F, Solomon B, Gregorc V, et al. Mass spectrometry to classify non -small- cell lung cancer patients ... non -small cell lung cancer. Int J Cancer. 2005; 11 3 (1) : 10 9 -15 . 98. Cappuzzo F, Magrini E, Ceresoli GL, et al. Akt phosphorylation and gefitinib efficacy in patients with advanced non -small- cell...
Ngày tải lên: 08/08/2014, 17:20
Báo cáo khoa học: "Pathological complete response induced by first-line chemotherapy with single agent docetaxel in a patient with advanced non small cell lung cancer" pptx
... advanced non small cell lung cancer Ferdinando Riccardi 1* , Giuseppe Di Lorenzo 1 , Carlo Buonerba 1 , Guglielmo Monaco 2 , Roberto Monaco 3 , Mimma Rizzo 1 , Sarah Scagliarini 1 , Florinda ... Florinda Scognamiglio 1 , Marilena Di Napoli 1 , Giacomo Carteni’ 1 Abstract Background: Defining the optimal treatment for patients with inoperable non small cell lung cancer (NSCLC), presenting ... few cycles should not automatically discourage to continue treatment. Introduction In non -small cell lung cancer (NSCLC), mediastinal lymphnode involvement comprises a wide spectrum of severity....
Ngày tải lên: 09/08/2014, 03:21
Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot
... = 11 ) pvalue* MLD 11 .59(6.53 -18 .11 ) Gy = 11 .26, SD = 2. 81 = 14 . 91, SD = 2. 91 0.0 01 NTCP 2.33% (0. 51- 9.68%) = 2. 51, SD = 1. 73 = 5.94, SD = 2.40 0.0 01 V5 58.73% (32.89-97.65%) = 58.43, SD = 16 .57 ... SD = 12 .47 0.006 V10 42 .16 %(25.28-83.34%) = 41. 13, SD = 12 .69 = 52.42, SD = 11 .05 0.0 01 V15 29.53% (16 .46-58. 51% ) = 28.94, SD = 9 .12 = 38.30, SD = 7.65 0.005 V20 18 .15 % (9.46- 31. 08%) = 18 .59, ... = 4.64 0. 011 V40 8.20% (3.29 -13 . 61% ) = 5. 91, SD = 2.48 = 9.26, SD = 3.75 0. 015 V45 7.42% (2.73 -10 .99%) = 4. 41, SD = 2.25 = 6.54, SD = 3.47 0.007 V50 7.07% (1. 94-8.82%) = 3 .15 , SD = 1. 94 = 4.89,...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo khoa học: " Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer" potx
... performance status (%) 0 31 (27) 17 1 (62) 28 (7) 31 (1) Unknown 4 (3) Weight loss before treatment (%) ≥ 10 % 24 ( 21) < 10 % 91 (79) AJCC stage grouping (%) IA/IB 22 (19 ) IIA/IIB 5 (4) IIIA 34 (30) IIIB ... failure and cancer death in such patients, suggesting little value of ENI in this cohort. Published: 30 January 2009 Radiation Oncology 2009, 4:5 doi :10 .11 86 /17 48- 717 X-4-5 Received: 19 November ... survival of patients with unre- sectable non-oat cell carcinoma of the lung: report by the Radiation Therapy Oncology Group. Cancer 19 82, 50 :10 91- 1099. 2. Bradley J, Thorstad W, Mutic S, Miller...
Ngày tải lên: 09/08/2014, 09:22
Báo cáo khoa học: "Radiotherapy quality assurance review in a multi-center randomized trial of limited-disease small cell lung cancer: the Japan Clinical Oncology Group (JCOG) trial 0202" pptx
... 2009 Radiation Oncology 2009, 4 :16 doi :10 .11 86 /17 48- 717 X-4 -16 Received: 20 February 2009 Accepted: 2 June 2009 This article is available from: http://www.ro-journal.com/content/4 /1/ 16 â 2009 Sanuki-Fujimoto ... for Cancer Control and Information Services, National Cancer Center 5 -1- 1 Tsukiji, Chuo-ku, Tokyo 10 4-0045, Japan and 3 JCOG lung cancer study group, Thoracic Oncology Division, National Cancer ... Tamura 3 Address: 1 Clinical Trials and Practice Support Division, Center for Cancer Control and Information Services, National Cancer Center, 5 -1- 1 Tsukiji, Chuo-ku, Tokyo 10 4-0045, Japan, 2 JCOG...
Ngày tải lên: 09/08/2014, 09:22