small cell lung cancer spread to brain and liver

Ngày tải lên: 11/08/2014, 12:20

... G, Gozzelino F, Tonato M: Gemcitabine and cisplatin versus mito- mycin, ifosfamide, and cisplatin in advanced non -small- cell lung cancer: a randomized phase III study of the Italian Lung Cancer Project. ... J Cancer 2001, 94:153-156. 2. Non -small Cell Lung Cancer Collaborative Group: Chemotherapy in non small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomized ... Di Costanzo F, Frontini L, Tonato M: Italian Lung Cancer Project. Phase III randomized trial comparing three platinum-based doublets in advanced non small- cell lung cancer. J Clin Oncol 2002,...

Ngày tải lên: 18/06/2014, 15:20

... non -small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy Anhui Shi, Guangying Zhu*, Hao Wu, Rong Yu, Fuhai Li and Bo Xu Abstract Background: To evaluate ... clinical, dosimetric factors and severe acute radiation pneumonitis (SARP) in patients with locally advanced non -small cell lung cancer (LANSCLC) treated with concurrent chemotherapy and intensity-modulated ... standard method for the management of unresectable locally advanced non- small cell lung cancer (NSCLC). Unfortunately, the longer survival is achieved at the price of greater toxicity of the lung...

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Ngày tải lên: 10/08/2014, 10:21

Ngày tải lên: 10/08/2014, 10:21

Ngày tải lên: 10/08/2014, 10:21

Ngày tải lên: 10/08/2014, 10:21

Ngày tải lên: 11/08/2014, 08:21

Ngày tải lên: 11/08/2014, 19:21

Ngày tải lên: 12/08/2014, 18:21

... mutations in lung cancer patients. Methods: EGFR mutation status was analyzed by DNA assays, and compared with IHC results in five non -small- cell lung cancer (NSCLC) cell lines and tumor samples ... Non -small- cell lung cancer harbouring mutations in the EGFR kinase domain. Clin Transl Oncol 2010, 12:75-80. 9. Gazdar AF: Activating and resistance mutations of EGFR in non -small- cell lung cancer: ... epidermal growth factor receptor mutation-specific antibodies for non -small cell lung cancer: immunohistochemistry as a possible screening method for epidermal growth factor receptor mutations. J...

Ngày tải lên: 18/06/2014, 16:20

... Martinelli 1,4* Abstract Background: Lung cancers consist of four major types that and for clinical-pathological reasons are often divided into two broad categories: small cell lung cancer (SCLC) and non -small cell lung cancer ... Schwemberger S, Tomlinson CR, Sartor MA, et al: Ligand-independent regulation of transforming growth factor β1 expression and cell cycle progression by the aryl hydrocarbon receptor. Mol Cell Biol ... cancers, and might have a role in other malignancies including vulva, skin, oesophagus, head and neck cancer. HPV has also been speculated to have a role in the pathogenesis of lung cancer. To...

Ngày tải lên: 18/06/2014, 16:20

... tumor cells versus stromal cells in non small cell lung cancer. Clin Cancer Res 2007, 13:6649-57. 24. World Health Organization: Histological Typing of Lung and Pleural Tumours. Geneva, Switzerland: ... according to NSCLC histology. Lung Cancer 2010. 31. Donnem T, Al-Saad S, Al-Shibli K, Andersen S, Busund LT, Bremnes RM: Prognostic impact of platelet-derived growth factors in non -small cell lung cancer ... various histological subtypes and stages of lung cancer may help to predict thetoxicityandsusceptibility to future RNA targeted therapies. Figure 2 Disease-specific survival curves according to miR-155 expression...

Ngày tải lên: 18/06/2014, 16:20

... approximately 29,000 people died from lung cancer in England and Wales[1] and it is the most com- mon and the most life-threatening form of cancer in Scot- land [2]. Lung cancer is also a major cause ... Staging of small cell and non -small cell lung cancer. University of Iowa Virtual Hos- pital; 1999. 6. Hopwood P, Stephens RJ: Symptoms at presentation for treat- ment in patients with lung cancer: ... were randomized into two selections (A and B) of progressive, stable and responding health states and toxic- ities. All participants were randomly assigned to rate the following: stable and responding...

Ngày tải lên: 18/06/2014, 19:20

... Lung cancer is one of the most common human cancers and the leading cause of cancer death world- wide (1). Lung cancer is generally classified into two histological types, small cell lung cancer ... sensitivity to gefitinib in non -small cell lung cancer cell lines. Mol Cancer Res. 2006; 4(8): 521-8. 102. Taguchi F, Solomon B, Gregorc V, et al. Mass spectrometry to classify non -small- cell lung cancer ... growth factor receptor and non -small- cell lung cancer. J Med Genet. 2007; 44(3): 166-72. 41. Riely GJ, Pao W, Pham D, et al. Clinical course of patients with non -small cell lung cancer and epidermal...

Ngày tải lên: 08/08/2014, 17:20

... tumor shrinkage, with no additional toxicity, and gave the patient the possibility to undergo a lobectomy rather than a pneumectomy, with the obvious advantages of a less invasive and more limited surgical ... agent docetaxel in a patient with advanced non small cell lung cancer Ferdinando Riccardi 1* , Giuseppe Di Lorenzo 1 , Carlo Buonerba 1 , Guglielmo Monaco 2 , Roberto Monaco 3 , Mimma Rizzo 1 , Sarah Scagliarini 1 , ... obtain a response after the first few cycles should not automatically discourage to continue treatment. Introduction In non -small cell lung cancer (NSCLC), mediastinal lymphnode involvement comprises...

Ngày tải lên: 09/08/2014, 03:21

... non -small cell lung cancer. Lung Cancer 2003, 41:1-11. 17. Shibamoto Y, Yukawa Y, Tsutsui K, Takahashi M, Abe M: Variation in the hypoxic fraction among mouse tumors of different types, sizes, and sites. ... 75:343-347. 11. Baba F, Shibamoto Y, Tomita N, Ikeya-Hashizume C, Oda K, Ayakawa S, Ogino H, Sugie C: Stereotactic body radiotherapy for stage I lung cancer and small lung metastasis: evaluation ... non -small- cell lung cancer: clinical implications. Radiother Oncol 2010, 94:1-11. 27. Chen Y, Guo W, Lu Y, Zou B: Dose-individualized stereotactic body radiotherapy for T1-3N0 non -small cell lung...

Ngày tải lên: 09/08/2014, 09:20

... interruptions to palliate the toxicity from concurrent chemoradiation for limited small cell lung cancer decreases survival and disease control. Lung Cancer 2001, 33:249-258. 26. Cisplatin, etoposide, and ... morphological characteristics of permanent human small cell lung cancer cell lines. J Cancer Res Clin Oncol 1987, 113:31-40. 16. NCCN guidelines for small- cell lung cancer. [http://www.nccn.org/ professionals/physician_gls/f_guidelines.asp]. 17. ... in limited-stage small cell lung cancer: facts, questions, prospects. Radiother Oncol 2000, 55:1-9. 2. Murray N, Turrisi AT: A review of first-line treatment for small- cell lung cancer. J Thorac...

Ngày tải lên: 09/08/2014, 09:20

... Stereotactic Body Rad iotherapy, Oligometastases, Non -Small Cell Lung Cancer Background Non -small cell lung cancer (NSCLC) is the leading cause of cancer mortality in the United States [1]. Patients ... and was postulated to be a poor prognostic factor in lung cancer. Similarly, Bradley et al. demonstrated the prognostic value of GTV determined on planning CT scans to be associated with OS and ... limited stage IV non -small cell lung cancer Praveena Cheruvu 1 , Su K Metcalfe 1 , Justin Metcalfe 1 , Yuhchyau Chen 1 , Paul Okunieff 2 and Michael T Milano 1* Abstract Background: Standard therapy...

Ngày tải lên: 09/08/2014, 09:20