small cell lung cancer spread to bones life expectancy
báo cáo hóa học:" Randomized phase II study with two gemcitabine- and docetaxel-based combinations as first-line chemotherapy for metastatic non-small cell lung cancer" docx
Ngày tải lên :
18/06/2014, 15:20
... Estimating the world cancer
burden: Globocan 2000. Int J Cancer 2001, 94:153-156.
2. Non -small Cell Lung Cancer Collaborative Group: Chemotherapy
in non small cell lung cancer: a meta-analysis ... G,
Gozzelino F, Tonato M: Gemcitabine and cisplatin versus mito-
mycin, ifosfamide, and cisplatin in advanced non -small- cell
lung cancer: a randomized phase III study of the Italian Lung
Cancer Project. ... Di Costanzo F, Frontini L, Tonato M: Italian
Lung Cancer Project. Phase III randomized trial comparing
three platinum-based doublets in advanced non small- cell
lung cancer. J Clin Oncol 2002,...
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Báo cáo hóa học: " Detection of EGFR mutations with mutation-specific antibodies in stage IV non-small-cell lung cancer" pdf
Ngày tải lên :
18/06/2014, 16:20
... epidermal growth factor
receptor mutation-specific antibodies for non -small cell lung cancer:
immunohistochemistry as a possible screening method for epidermal
growth factor receptor mutations. J ... Non -small- cell lung cancer harbouring mutations in the EGFR
kinase domain. Clin Transl Oncol 2010, 12:75-80.
9. Gazdar AF: Activating and resistance mutations of EGFR in non -small- cell
lung cancer: ... Haluska FG, et al:
Activating mutations in the epidermal growth factor receptor
underlying responsiveness of non -small- cell lung cancer to gefitinib. N
Engl J Med 2004, 350:2129-2139.
5. Paez JG, Janne...
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Báo cáo hóa học: "Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins" ppt
Ngày tải lên :
18/06/2014, 16:20
... Martinelli
1,4*
Abstract
Background: Lung cancers consist of four major types that and for clinical-pathological reasons are often divided
into two broad categories: small cell lung cancer (SCLC) and non -small cell lung cancer ... oesophagus, head and
neck cancer. HPV has also been speculated to have a role in the pathogenesis of lung cancer. To validate the
hypothesis of HPV involvement in small cell lung cancer pathogenesis ... according to sub-
cellular localization. The genes in this pathway have
ascribed not only to detoxification mechanism, but also
to functions such as cell cycle progression, cance r and
cell proliferation....
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Báo cáo hóa học: "Prognostic Impact of MiR-155 in Non-Small Cell Lung Cancer Evaluated by in Situ Hybridization" pot
Ngày tải lên :
18/06/2014, 16:20
... marker expression in tumor cells versus stromal cells in non
small cell lung cancer. Clin Cancer Res 2007, 13:6649-57.
24. World Health Organization: Histological Typing of Lung and Pleural
Tumours. ... in
non -small cell lung cancer. Clin Cancer Res 2008, 14:5220-7.
30. Andersen S, Eilertsen M, Donnem T, et al: Diverging prognostic impacts of
hypoxic markers according to NSCLC histology. Lung Cancer ... the cytoplasm of most neo-
plastic tumor cells and to a lesser extent expressed in
the cytoplasm of normal epithelial cells in lung tissue.
Based on m orphological cr iteria, infla mmatory cells
(macrophages,...
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báo cáo hóa học: " Health state utilities for non small cell lung cancer" pot
Ngày tải lên :
18/06/2014, 19:20
... Staging of small cell
and non -small cell lung cancer. University of Iowa Virtual Hos-
pital; 1999.
6. Hopwood P, Stephens RJ: Symptoms at presentation for treat-
ment in patients with lung cancer: ... Research and Treatment of
Cancer Quality-of -Life Questionnaire -Lung Cancer- 17
items; EQ-5D: EuroQoL-5 Dimensions; HRQL: Health-
related Quality of Life; NSCLC: Non -Small Cell Lung Can-
cer; SF-36: ... breast cancer. Br J Cancer 2006,
95(6):683-90.
17. Cancer Research UK [http://www.cancerresearchuk.org
]
18. Cancer Help [http://www.cancerhelp.org.uk
]
19. Association for International Cancer...
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Báo cáo toán học: "Molecular Predictors of EGFR-TKI Sensitivity in Advanced Non–small Cell Lung Cancer" ppsx
Ngày tải lên :
08/08/2014, 17:20
... sensitivity to gefitinib in non -small cell lung cancer
cell lines. Mol Cancer Res. 2006; 4(8): 521-8.
102. Taguchi F, Solomon B, Gregorc V, et al. Mass spectrometry to
classify non -small- cell lung cancer ... cause of cancer death world-
wide (1). Lung cancer is generally classified into two
histological types, small cell lung cancer (SCLC) and
non small cell lung cancer (NSCLC).
NSCLC accounts
for ... growth
factor receptor and non -small- cell lung cancer. J Med Genet.
2007; 44(3): 166-72.
41. Riely GJ, Pao W, Pham D, et al. Clinical course of patients with
non -small cell lung cancer and...
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Báo cáo khoa học: "Pathological complete response induced by first-line chemotherapy with single agent docetaxel in a patient with advanced non small cell lung cancer" pptx
Ngày tải lên :
09/08/2014, 03:21
... obtain a response after the first few cycles should not
automatically discourage to continue treatment.
Introduction
In non -small cell lung cancer (NSCLC), mediastinal
lymphnode involvement comprises ... agent
docetaxel in a patient with advanced non small
cell lung cancer
Ferdinando Riccardi
1*
, Giuseppe Di Lorenzo
1
, Carlo Buonerba
1
, Guglielmo Monaco
2
, Roberto Monaco
3
,
Mimma Rizzo
1
, Sarah Scagliarini
1
, ... Carteni’
1
Abstract
Background: Defining the optimal treatment for patients with inoperable non small cell lung cancer (NSCLC),
presenting with metastatic mediastinal lymph nodes, is challenging. Nevertheless,...
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Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot
Ngày tải lên :
09/08/2014, 08:23
... symptoms of radiation pneu-
monitis can lead to a poor quality of life for lung cancer
patients. Severe radiation pneumonitis after CCRT can
be life- threatening if patients are not responsive to ... of unresectable locally advanced non-
small cell lung cancer (NSCLC). Unfortunately, the longer
survival is achieved at the price of greater toxicity of the
lung and the esophageal mucosa [3-5].
* ... Venkatraman
ES, Burman CM, Leibel SA, Ling CC: Dose-volume factors contributing to
the incidence of radiation pneumonitis in non -small- cell lung cancer
patients treated with three-dimensional conformal...
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Báo cáo khoa học: "Clinical outcomes of stereotactic body radiotherapy for stage I non-small cell lung cancer using different doses depending on tumor size" ppsx
Ngày tải lên :
09/08/2014, 09:20
... non -small- cell lung
cancer. Int J Radiat Oncol Biol Phys 2002, 52:382-389.
16. Qiao X, Tullgren O, Lax I, Sirzén F, Lewensohn R: The role of radiotherapy
in treatment of stage I non -small cell lung ... non -small- cell lung cancer: clinical implications. Radiother Oncol
2010, 94:1-11.
27. Chen Y, Guo W, Lu Y, Zou B: Dose-individualized stereotactic body
radiotherapy for T1-3N0 non -small cell lung ... M, Yamazaki K, Onodera Y, Taguchi H, Katoh N,
Hommura F, Oizumi S, Nishimura M, Shirato H: Steep dose-response
relationship for stage I non -small- cell lung cancer using
hypofractionated high-dose...
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Báo cáo khoa học: "The effect of bioequivalent radiation dose on survival of patients with limited-stage small-cell lung cancer" pdf
Ngày tải lên :
09/08/2014, 09:20
... morphological characteristics of
permanent human small cell lung cancer cell lines. J Cancer Res Clin
Oncol 1987, 113:31-40.
16. NCCN guidelines for small- cell lung cancer. [http://www.nccn.org/
professionals/physician_gls/f_guidelines.asp].
17. ... interruptions to palliate the
toxicity from concurrent chemoradiation for limited small cell lung
cancer decreases survival and disease control. Lung Cancer 2001,
33:249-258.
26. Cisplatin, etoposide, ... in limited-stage small
cell lung cancer: facts, questions, prospects. Radiother Oncol 2000, 55:1-9.
2. Murray N, Turrisi AT: A review of first-line treatment for small- cell lung
cancer. J Thorac...
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Báo cáo khoa học: " Comparison of outcomes in patients with stage III versus limited stage IV non-small cell lung cancer" docx
Ngày tải lên :
09/08/2014, 09:20
... Stereotactic Body Rad iotherapy, Oligometastases, Non -Small Cell Lung Cancer
Background
Non -small cell lung cancer (NSCLC) is the leading
cause of cancer mortality in the United States [1].
Patients ... progression and was postulated
to be a poor prognostic factor in lung cancer. Similarly,
Bradley et al. demonstrated the prognostic value of
GTV determined on planning CT scans to be associated
with OS ... treatments have shown to be beneficial. Ser-
ies describing surgical metastectomy have the largest
patient numbers and longest follow up [12-14]. Surgical
metastatectomy is proposed to be a curative...
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Báo cáo khoa học: "Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study" pps
Ngày tải lên :
09/08/2014, 09:22
... 18 to 22 25 > 25 to 28
Oesophagus 1 24 > 24 to 27 27 > 27 to 28.5
Ipsilateral Brachial Plexus 1 24 > 24 to 26 27 > 27 to 29
Heart 1 24 > 24 to 26 27 > 27 to 29
Trachea and ... contrast to the ITV to
PTV margin discussed previously, the CTV to PTV margin
needed here should take the tumour motion into account.
However, similar to the reasoning given for the ITV to PTV
margin, ... [33].
Also, patient set-up corrections due to tumour shifts lead
to a change in the dose given to the OAR. To avoid exces-
sive doses to OAR, it is recommended to evaluate the
impact of such shifts...
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Báo cáo khoa học: " Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer" potx
Ngày tải lên :
09/08/2014, 09:22
... when
treating non -small cell lung carcinoma (NSCLC) to
deliver 40 to 50 Gy to the uninvolved regional lymph
nodes. Known as elective nodal irradiation (ENI), this
therapy is targeted to ipsilateral ... Jeremic B:
Report from the international atomic energy agency (IAEA)
consultants' meeting on elective nodal irradiation in lung
cancer: non -small cell lung cancer (NSCLC). Int J Radiat Oncol
Biol ... Komaki R, Cox JD: Intrathoracic patterns of fail-
ure for non -small- cell lung cancer with position-emission
tomography/computed tomography defined target delinea-
tion. Int J Radiat Oncol Biol...
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Báo cáo khoa học: "Radiotherapy quality assurance review in a multi-center randomized trial of limited-disease small cell lung cancer: the Japan Clinical Oncology Group (JCOG) trial 0202" pptx
Ngày tải lên :
09/08/2014, 09:22
... multi-center
randomized trial of limited-disease small cell lung cancer: the Japan
Clinical Oncology Group (JCOG) trial 0202
Naoko Sanuki-Fujimoto
†1
, Satoshi Ishikura*
†1,2
, Kazushige Hayakawa
2
, ... for Cancer Control and
Information Services, National Cancer Center 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan and
3
JCOG lung cancer study group, Thoracic
Oncology Division, National Cancer ... III non -small cell lung
cancer; however, due to excessive serious adverse events,
the trial was terminated early when 46 patients were reg-
istered. By retrospective RT QA review, a protocol viola-
tion...
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Báo cáo khoa học: " Evalution of surface-based deformable image registration for adaptive radiotherapy of non-small cell lung cancer (NSCLC)" pptx
Ngày tải lên :
09/08/2014, 10:20
... Corresponding author
Abstract
Background: To evaluate the performance of surface-based deformable image registration (DR)
for adaptive radiotherapy of non -small cell lung cancer (NSCLC).
Methods: Based ... not possible
in all patients and these OARs were included into the
GTV. This was done because the OARs were too small for
manual and automatic segmentation or because separa-
tion of GTV and OARs ... par-
tially in 9/13 patients. To cope with this issue, DR algo-
rithms needed to know that one voxel can belong to two
different organs with different corresponding deforma-
tion vectors.
Major disadvantage...
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