... 69 61 57 21 7 60 SCC 1 0 7 1 12 0 LCC 5 0 4 11 0 others 3 0 2 0 0 EGFR exon 19 29 10 18 21 55 58 21 exon21 27 0 12 14 18 56 23 wild-type 22 51 29 29 6 145 167 16 IHC sensitivity overall 92% delE746-A750 ... non -small- cell lung cancer. Clin Cancer Res 20 09, 15:3 023 -3 028 . 13. Motoi N, Szoke J, Riely GJ, Seshan VE, Kris MG, Rusch VW, Gerald WL, Travis WD: Lung adenocarcinoma: modification of the 20 04 ... anticancer agents. Nat Rev Cancer 20 10, 10 :24 1 -25 3. 2. Sharma SV, Bell DW, Settleman J, Haber DA: Epidermal growth factor receptor mutations in lung cancer. Nat Rev Cancer 20 07, 7:169-181. 3. Kosaka...
Ngày tải lên: 18/06/2014, 16:20
... non -small- cell lung cancer. Int J Radiat Oncol Biol Phys 20 02, 52: 3 82- 389. 16. Qiao X, Tullgren O, Lax I, Sirzén F, Lewensohn R: The role of radiotherapy in treatment of stage I non -small cell lung ... phase II trial of medically inoperable stage I non -small- cell lung cancer patients treated with stereotactic body radiotherapy. J Clin Oncol 20 09, 27 : 329 0- 329 6. 6. Takeda A, Sanuki N, Kunieda E, ... size (mm) Range (median) 12- 55 (27 ) 12, 14 15-34 (24 ) 31-55 (35) Operability Operable 40 2 27 11 Non-operable 84 0 58 26 Histology Adenocarcinoma 66 2 46 18 Squamous cell carcinoma 35 0 19 16 Unclassified...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: "The effect of bioequivalent radiation dose on survival of patients with limited-stage small-cell lung cancer" pdf
... 106(78.5) LDH 0.517 22 0 IU/L 35(43.1) 34(35.3) > ;22 0 IU/L 25 (26 .4) 78 (22 .6) Unknown 10(30.5) 23 ( 42. 1) ISN 0.190 Yes 8(11.4) 25 (18.5) No 62( 88.6) 110(81.5) CHT cycles 0. 620 Median 4 6 Range ... in lung cancer: small- cell lung cancer (SCLC). Int J Radiat Oncol Biol Phys 20 08, 72: 327 -334. 33. Roof KS, Fidias P, Lynch TJ, Choi NC: Radiation dose intensification in limited -stage small- cell ... limited -stage small cell lung cancer. [http:// clinicaltrials.gov/ct2/show/NCT00433563]. 27 . Three different radiation therapy regimens in treating patients with limited -stage small cell lung cancer...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: " Comparison of outcomes in patients with stage III versus limited stage IV non-small cell lung cancer" docx
... Non -Small Cell Lung Cancer Background Non -small cell lung cancer (NSCLC) is the leading cause of cancer mortality in the United States [1]. Patients with stage IV NSCLC typically have a poor prognosis, ... April 20 11 Accepted: 30 June 20 11 Published: 30 June 20 11 References 1. Jemal A, Siegel R, Xu J, Ward E: Cancer Statistics, 20 10. CA Cancer J Clin 20 10, 60(5) :27 7-300, Epub 20 10 Jul 7. 2. Greene ... Oncology 20 11, 6:80 http://www.ro-journal.com/content/6/1/80 Page 2 of 7 RESEARC H Open Access Comparison of outcomes in patients with stage III versus limited stage IV non -small cell lung cancer Praveena...
Ngày tải lên: 09/08/2014, 09:20
Báo cáo khoa học: "Recommendations for implementing stereotactic radiotherapy in peripheral stage IA non-small cell lung cancer: report from the Quality Assurance Working Party of the randomised phase III ROSEL study" pps
... > 18 to 22 25 > 25 to 28 Oesophagus 1 24 > 24 to 27 27 > 27 to 28 .5 Ipsilateral Brachial Plexus 1 24 > 24 to 26 27 > 27 to 29 Heart 1 24 > 24 to 26 27 > 27 to 29 Trachea ... body radiotherapy for stage I non -small cell lung cancer. Radiother Oncol 20 07, 85: 429 -434. 39. Sinha B, McGarry RC: Stereotactic body radiotherapy for bilat- eral primary lung cancers: the Indiana ... and 108 cc)Figure 5 Percent of lung (both lungs minus GTV) receiving 20 Gy or more (V 20 Gy ) from a total of 22 patients with stage I tumours and 4 patients with stage 1B tumours (with PTVs of...
Ngày tải lên: 09/08/2014, 09:22
Báo cáo khoa học: " Stereotactic, single-dose irradiation of stage I non-small cell lung cancer and lung metastases" docx
Ngày tải lên: 09/08/2014, 10:21
báo cáo hóa học:" Randomized phase II study with two gemcitabine- and docetaxel-based combinations as first-line chemotherapy for metastatic non-small cell lung cancer" docx
... (OS) (B). 0 4 8 121 620 2 428 323 6404448 52 Weeks 0 0 .2 0.4 0.6 0.8 1 TTP Patients Events (%) Arm A 35 33 (94.3) Arm B 34 32 (94.1) A 0 4 8 12 16 20 24 28 32 36 40 44 48 52 Weeks 0 0 .2 0.4 0.6 0.8 1 Survival Patients ... Estimating the world cancer burden: Globocan 20 00. Int J Cancer 20 01, 94:153-156. 2. Non -small Cell Lung Cancer Collaborative Group: Chemotherapy in non small cell lung cancer: a meta-analysis ... chemotherapy in patients with advanced non -small cell lung cancer: a lung cancer Galician group phase II study. Cancer Chemother Pharma- col 20 07, 60: 725 -7 32. 20 . Binder D, Sailer V, Schweigert M,...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: "Involvement of aryl hydrocarbon receptor signaling in the development of small cell lung cancer induced by HPV E6/E7 oncoproteins" ppt
... risk marker of lung cancer in Taiwan. Cancer 20 03, 97:1558-1563. 11. Klein F, Amin Kotb WF, Petersen I: Incidence of human papilloma virus in lung cancer. Lung Cancer 20 09, 65:13-18. 12. Zochbauer-Muller ... are often divided into two broad categories: small cell lung cancer (SCLC) and non -small cell lung cancer (NSCLC). All major histological types of lung cancer are associated with smoking, although ... liver carcinogenesis. Cancer Res 20 10, 70 :21 2 -22 0. 34. Puga A, Xia Y, Elferink C: Role of the aryl hydrocarbon receptor in cell cycle regulation. Chem Biol Interact 20 02, 141:117-130. 35. Chang...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: "Prognostic Impact of MiR-155 in Non-Small Cell Lung Cancer Evaluated by in Situ Hybridization" pot
... with bevacizumab for non -small- cell lung cancer. N Engl J Med 20 06, 355 :25 42- 50. 21 . Besse B, Ropert S, Soria JC: Targeted therapies in lung cancer. Ann Oncol 20 07, 18(Suppl 9):ix135-ix1 42. 22 . Scagliotti ... Wedge* 24 3 73 190 61 Pneumonectomy 92 27 37 47 Pathological stage <0.001 I 157 47 190 71 II 136 41 61 51 IIIa 42 12 17 23 Tumor status <0.001 1 85 25 190 74 2 188 56 84 57 3 621 925 36 Nodal ... status <0.001 0 23 2 69 190 66 17 623 3543 2 27 8 18 18 Surgical margins 0 .29 Free 307 92 190 58 Not free 28 8 47 47 Vascular infiltration <0.001 No 28 4 85 190 58 Yes 51 15 27 32 NR, not reached. *...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " Health state utilities for non small cell lung cancer" pot
... A, Ward E, Thun MJ: Cancer statistics, 20 03. CA Cancer J Clin 20 03, 53:5 -26 . 5. Busick NP, Fretz PC, Galvin JR, Peterson MW: Staging of small cell and non -small cell lung cancer. University of ... NSCLC. Background In 20 02, approximately 29 ,000 people died from lung cancer in England and Wales[1] and it is the most com- mon and the most life-threatening form of cancer in Scot- land [2] . Lung cancer ... Lilenbaum R: Chemothera- peutic management of stage IV non -small cell lung cancer. Chest 20 03, 123 :22 65-435. Health and Quality of Life Outcomes 20 08, 6:84 http://www.hqlo.com/content/6/1/84 Page 7...
Ngày tải lên: 18/06/2014, 19:20
Báo cáo toán học: "Molecular Predictors of EGFR-TKI Sensitivity in Advanced Non–small Cell Lung Cancer" ppsx
... Biol. 20 01; 2( 2): 127 -37. 11. Scagliotti GV, Selvaggi G, Novello S, et al. The biology of epi- dermal growth factor receptor in lung cancer. Clin Cancer Res. 20 04; 10( 12 Pt 2) : 422 7s-32s. 12. ... advanced non -small- cell lung cancer previously treated with platinum-containing chemotherapy regimens. The TAX 320 Non -Small Cell Lung Cancer Study Group. J Clin Oncol. 20 00; 18( 12) : 23 54- 62. 7. ... gefitinib in non -small cell lung cancer cell lines. Mol Cancer Res. 20 06; 4(8): 521 -8. 1 02. Taguchi F, Solomon B, Gregorc V, et al. Mass spectrometry to classify non -small- cell lung cancer patients...
Ngày tải lên: 08/08/2014, 17:20
Báo cáo khoa học: "Pathological complete response induced by first-line chemotherapy with single agent docetaxel in a patient with advanced non small cell lung cancer" pptx
... agent docetaxel in a patient with advanced non small cell lung cancer Ferdinando Riccardi 1* , Giuseppe Di Lorenzo 1 , Carlo Buonerba 1 , Guglielmo Monaco 2 , Roberto Monaco 3 , Mimma Rizzo 1 , Sarah ... treatment. Introduction In non -small cell lung cancer (NSCLC), mediastinal lymphnode involvement comprises a wide spectrum of severity. In fact, while 9% of patients with IIIA-N2 NSCLC is candidate for ... Carteni’ 1 Abstract Background: Defining the optimal treatment for patients with inoperable non small cell lung cancer (NSCLC), presenting with metastatic mediastinal lymph nodes, is challenging. Nevertheless,...
Ngày tải lên: 09/08/2014, 03:21
Báo cáo khoa học: "Analysis of clinical and dosimetric factors associated with severe acute radiation pneumonitis in patients with locally advanced non-small cell lung cancer treated with concurrent chemotherapy and intensity-modulated radiotherapy" pot
... 7.09 0.0 02 V25 12. 96% (5.90 -26 .26 %) = 12. 88, SD = 4. 42 = 20 .91, SD = 6.98 0.001 V30 10.00% (4.68 -21 .43%) = 9. 72, SD = 3.45 = 15.69, SD = 6.00 0.008 V35 9. 92% (3.89-18.65%) = 7.57, SD = 2. 86 = ... 11 .26 , SD = 2. 81 = 14.91, SD = 2. 91 0.001 NTCP 2. 33% (0.51-9.68%) = 2. 51, SD = 1.73 = 5.94, SD = 2. 40 0.001 V5 58.73% ( 32. 89-97.65%) = 58.43, SD = 16.57 = 69 .23 , SD = 12. 47 0.006 V10 42. 16% (25 .28 -83.34%) ... 42. 16% (25 .28 -83.34%) = 41.13, SD = 12. 69 = 52. 42, SD = 11.05 0.001 V15 29 .53%(16.46-58.51%) = 28 .94, SD = 9. 12 = 38.30, SD = 7.65 0.005 V20 18.15% (9.46-31.08%) = 18.59, SD = 6.03 = 28 . 02, SD...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo khoa học: " Exclusion of elective nodal irradiation is associated with minimal elective nodal failure in non-small cell lung cancer" potx
... (IAEA) consultants' meeting on elective nodal irradiation in lung cancer: non -small cell lung cancer (NSCLC). Int J Radiat Oncol Biol Phys 20 08, 72( 2):335-3 42. 6. Therasse P, Arbuck SG, Eisenhauer EA, Wanders ... (37) Squamous cell carcinoma 39 (34) Large cell carcinoma 3 (3) Mixed 2 (2) Non -small cell not otherwise specified 28 (24 ) Grade (%) Well-differentiated 7 (6) Moderately differentiated 12 (10) Poorly ... Clin Oncol 20 05, 28 :597-6 02. 15. Chang JY, Liu HH, Komaki R: Intensity modulated radiation therapy and proton radiotherapy for non -small cell lung can- cer. Curr Oncol Rep 20 05, 7 :25 5-9. 16....
Ngày tải lên: 09/08/2014, 09:22
Báo cáo khoa học: "Radiotherapy quality assurance review in a multi-center randomized trial of limited-disease small cell lung cancer: the Japan Clinical Oncology Group (JCOG) trial 0202" pptx
... JCOG 020 2 seemed to be acceptable, providing reliable results. Published: 2 June 20 09 Radiation Oncology 20 09, 4:16 doi:10.1186/1748-717X-4-16 Received: 20 February 20 09 Accepted: 2 June 20 09 This ... trial of limited-disease small cell lung cancer: the Japan Clinical Oncology Group (JCOG) trial 020 2 Naoko Sanuki-Fujimoto †1 , Satoshi Ishikura* †1 ,2 , Kazushige Hayakawa 2 , Kaoru Kubota 3 , ... periodically at least twice a month by the RT Schema of JCOG 020 2Figure 1 Schema of JCOG 020 2. Abbreviations. LD-SCLC, limited- disease small cell lung cancer; PS, performance status; EP, etoposide; CDDP,...
Ngày tải lên: 09/08/2014, 09:22