small cell lung cancer metastasis to bone

Ngày tải lên: 11/08/2014, 12:20

Ngày tải lên: 11/08/2014, 19:21

... Estimating the world cancer burden: Globocan 2000. Int J Cancer 2001, 94:153-156. 2. Non -small Cell Lung Cancer Collaborative Group: Chemotherapy in non small cell lung cancer: a meta-analysis ... G, Gozzelino F, Tonato M: Gemcitabine and cisplatin versus mito- mycin, ifosfamide, and cisplatin in advanced non -small- cell lung cancer: a randomized phase III study of the Italian Lung Cancer Project. ... Di Costanzo F, Frontini L, Tonato M: Italian Lung Cancer Project. Phase III randomized trial comparing three platinum-based doublets in advanced non small- cell lung cancer. J Clin Oncol 2002,...

Ngày tải lên: 18/06/2014, 15:20

... epidermal growth factor receptor mutation-specific antibodies for non -small cell lung cancer: immunohistochemistry as a possible screening method for epidermal growth factor receptor mutations. J ... Non -small- cell lung cancer harbouring mutations in the EGFR kinase domain. Clin Transl Oncol 2010, 12:75-80. 9. Gazdar AF: Activating and resistance mutations of EGFR in non -small- cell lung cancer: ... Haluska FG, et al: Activating mutations in the epidermal growth factor receptor underlying responsiveness of non -small- cell lung cancer to gefitinib. N Engl J Med 2004, 350:2129-2139. 5. Paez JG, Janne...

Ngày tải lên: 18/06/2014, 16:20

... Martinelli 1,4* Abstract Background: Lung cancers consist of four major types that and for clinical-pathological reasons are often divided into two broad categories: small cell lung cancer (SCLC) and non -small cell lung cancer ... oesophagus, head and neck cancer. HPV has also been speculated to have a role in the pathogenesis of lung cancer. To validate the hypothesis of HPV involvement in small cell lung cancer pathogenesis ... according to sub- cellular localization. The genes in this pathway have ascribed not only to detoxification mechanism, but also to functions such as cell cycle progression, cance r and cell proliferation....

Ngày tải lên: 18/06/2014, 16:20

... marker expression in tumor cells versus stromal cells in non small cell lung cancer. Clin Cancer Res 2007, 13:6649-57. 24. World Health Organization: Histological Typing of Lung and Pleural Tumours. ... in non -small cell lung cancer. Clin Cancer Res 2008, 14:5220-7. 30. Andersen S, Eilertsen M, Donnem T, et al: Diverging prognostic impacts of hypoxic markers according to NSCLC histology. Lung Cancer ... the cytoplasm of most neo- plastic tumor cells and to a lesser extent expressed in the cytoplasm of normal epithelial cells in lung tissue. Based on m orphological cr iteria, infla mmatory cells (macrophages,...

Ngày tải lên: 18/06/2014, 16:20

... Staging of small cell and non -small cell lung cancer. University of Iowa Virtual Hos- pital; 1999. 6. Hopwood P, Stephens RJ: Symptoms at presentation for treat- ment in patients with lung cancer: ... breast cancer. Br J Cancer 2006, 95(6):683-90. 17. Cancer Research UK [http://www.cancerresearchuk.org ] 18. Cancer Help [http://www.cancerhelp.org.uk ] 19. Association for International Cancer ... life-threatening form of cancer in Scot- land [2]. Lung cancer is also a major cause of death throughout the rest of the world [3,4]. Non -small cell lung cancer (NSCLC) has a poor progno- sis. On average,...

Ngày tải lên: 18/06/2014, 19:20

... sensitivity to gefitinib in non -small cell lung cancer cell lines. Mol Cancer Res. 2006; 4(8): 521-8. 102. Taguchi F, Solomon B, Gregorc V, et al. Mass spectrometry to classify non -small- cell lung cancer ... cause of cancer death world- wide (1). Lung cancer is generally classified into two histological types, small cell lung cancer (SCLC) and non small cell lung cancer (NSCLC). NSCLC accounts for ... growth factor receptor and non -small- cell lung cancer. J Med Genet. 2007; 44(3): 166-72. 41. Riely GJ, Pao W, Pham D, et al. Clinical course of patients with non -small cell lung cancer and...

Ngày tải lên: 08/08/2014, 17:20

... obtain a response after the first few cycles should not automatically discourage to continue treatment. Introduction In non -small cell lung cancer (NSCLC), mediastinal lymphnode involvement comprises ... agent docetaxel in a patient with advanced non small cell lung cancer Ferdinando Riccardi 1* , Giuseppe Di Lorenzo 1 , Carlo Buonerba 1 , Guglielmo Monaco 2 , Roberto Monaco 3 , Mimma Rizzo 1 , Sarah Scagliarini 1 , ... Carteni’ 1 Abstract Background: Defining the optimal treatment for patients with inoperable non small cell lung cancer (NSCLC), presenting with metastatic mediastinal lymph nodes, is challenging. Nevertheless,...

Ngày tải lên: 09/08/2014, 03:21

... Xu Abstract Background: To evaluate the association between the clinical, dosimetric factors and severe acute radiation pneumonitis (SARP) in patients with locally advanced non -small cell lung cancer (LANSCLC) ... of unresectable locally advanced non- small cell lung cancer (NSCLC). Unfortunately, the longer survival is achieved at the price of greater toxicity of the lung and the esophageal mucosa [3-5]. * ... Venkatraman ES, Burman CM, Leibel SA, Ling CC: Dose-volume factors contributing to the incidence of radiation pneumonitis in non -small- cell lung cancer patients treated with three-dimensional conformal...

Ngày tải lên: 09/08/2014, 08:23

... 75:343-347. 11. Baba F, Shibamoto Y, Tomita N, Ikeya-Hashizume C, Oda K, Ayakawa S, Ogino H, Sugie C: Stereotactic body radiotherapy for stage I lung cancer and small lung metastasis: evaluation of ... non -small- cell lung cancer. Int J Radiat Oncol Biol Phys 2002, 52:382-389. 16. Qiao X, Tullgren O, Lax I, Sirzén F, Lewensohn R: The role of radiotherapy in treatment of stage I non -small cell lung ... non -small- cell lung cancer: clinical implications. Radiother Oncol 2010, 94:1-11. 27. Chen Y, Guo W, Lu Y, Zou B: Dose-individualized stereotactic body radiotherapy for T1-3N0 non -small cell lung...

Ngày tải lên: 09/08/2014, 09:20

... morphological characteristics of permanent human small cell lung cancer cell lines. J Cancer Res Clin Oncol 1987, 113:31-40. 16. NCCN guidelines for small- cell lung cancer. [http://www.nccn.org/ professionals/physician_gls/f_guidelines.asp]. 17. ... interruptions to palliate the toxicity from concurrent chemoradiation for limited small cell lung cancer decreases survival and disease control. Lung Cancer 2001, 33:249-258. 26. Cisplatin, etoposide, ... in limited-stage small cell lung cancer: facts, questions, prospects. Radiother Oncol 2000, 55:1-9. 2. Murray N, Turrisi AT: A review of first-line treatment for small- cell lung cancer. J Thorac...

Ngày tải lên: 09/08/2014, 09:20

... Stereotactic Body Rad iotherapy, Oligometastases, Non -Small Cell Lung Cancer Background Non -small cell lung cancer (NSCLC) is the leading cause of cancer mortality in the United States [1]. Patients ... progression and was postulated to be a poor prognostic factor in lung cancer. Similarly, Bradley et al. demonstrated the prognostic value of GTV determined on planning CT scans to be associated with OS ... treatments have shown to be beneficial. Ser- ies describing surgical metastectomy have the largest patient numbers and longest follow up [12-14]. Surgical metastatectomy is proposed to be a curative...

Ngày tải lên: 09/08/2014, 09:20

... 18 to 22 25 > 25 to 28 Oesophagus 1 24 > 24 to 27 27 > 27 to 28.5 Ipsilateral Brachial Plexus 1 24 > 24 to 26 27 > 27 to 29 Heart 1 24 > 24 to 26 27 > 27 to 29 Trachea and ... contrast to the ITV to PTV margin discussed previously, the CTV to PTV margin needed here should take the tumour motion into account. However, similar to the reasoning given for the ITV to PTV margin, ... [33]. Also, patient set-up corrections due to tumour shifts lead to a change in the dose given to the OAR. To avoid exces- sive doses to OAR, it is recommended to evaluate the impact of such shifts...

Ngày tải lên: 09/08/2014, 09:22

... when treating non -small cell lung carcinoma (NSCLC) to deliver 40 to 50 Gy to the uninvolved regional lymph nodes. Known as elective nodal irradiation (ENI), this therapy is targeted to ipsilateral ... Jeremic B: Report from the international atomic energy agency (IAEA) consultants' meeting on elective nodal irradiation in lung cancer: non -small cell lung cancer (NSCLC). Int J Radiat Oncol Biol ... Komaki R, Cox JD: Intrathoracic patterns of fail- ure for non -small- cell lung cancer with position-emission tomography/computed tomography defined target delinea- tion. Int J Radiat Oncol Biol...

Ngày tải lên: 09/08/2014, 09:22

... multi-center randomized trial of limited-disease small cell lung cancer: the Japan Clinical Oncology Group (JCOG) trial 0202 Naoko Sanuki-Fujimoto †1 , Satoshi Ishikura* †1,2 , Kazushige Hayakawa 2 , ... for Cancer Control and Information Services, National Cancer Center 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan and 3 JCOG lung cancer study group, Thoracic Oncology Division, National Cancer ... III non -small cell lung cancer; however, due to excessive serious adverse events, the trial was terminated early when 46 patients were reg- istered. By retrospective RT QA review, a protocol viola- tion...

Ngày tải lên: 09/08/2014, 09:22

... Corresponding author Abstract Background: To evaluate the performance of surface-based deformable image registration (DR) for adaptive radiotherapy of non -small cell lung cancer (NSCLC). Methods: Based ... not possible in all patients and these OARs were included into the GTV. This was done because the OARs were too small for manual and automatic segmentation or because separa- tion of GTV and OARs ... par- tially in 9/13 patients. To cope with this issue, DR algo- rithms needed to know that one voxel can belong to two different organs with different corresponding deforma- tion vectors. Major disadvantage...

Ngày tải lên: 09/08/2014, 10:20

Ngày tải lên: 09/08/2014, 10:21

Ngày tải lên: 09/08/2014, 10:21

Ngày tải lên: 09/08/2014, 10:21